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InCube Ventures

Venture studio

San Jose · Seed–Late Stage · 3 people tracked

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Investment thesis

InCube Labs is a life sciences innovation lab, not the expected InCube Ventures firm. It identifies major unsolved clinical problems in healthcare and develops novel therapies, spinning research projects into portfolio companies for product development, clinical trials, regulatory approval, and commercialization. Focus areas span urology, gastroenterology, women's health, CNS disorders, musculoskeletal conditions, metabolic diseases, and cancer, often via implantable devices, drug-delivery combinations, and biomaterials. It collaborates with affiliated entities InCube Ventures, VentureHealth, and Modulus for funding and manufacturing support.

Source: firm website, verified Aug 2, 2026.

Stage
Seed–Late Stage
HQ
San Jose, TX, US
Instruments
Equity
Founded
1995
Last 12 months
1 investment
AUM
$125M
Tracked investments
22

Team · 3 people

from the firm's website

What they invest in

from 5 of 22 portfolio companies

Healthtech ×3Biotech ×2Medical Devices ×2Deep Tech ×1Robotics ×1

HQs:United States×4

Investments · 22 tracked

founders shown can be your intro path
Rani Therapeutics HoldingsNASDAQ: RANIOct 2025SEC filingmedium confidence

BiotechSan Jose, US

Talat Imran(Executive Officer, Director)Svai Sanford(Executive Officer)Mir Hashim(Executive Officer)

BoardAbraham Bassan(Director)Vasudev Bailey, M.D.(Director)

Board seatMir Imran· per SEC Form D · $60.3M raise · filed Nov 2025

Rani Therapeuticsranitherapeutics.cominNASDAQ: RANI

HealthtechSan Jose, US

Mir Hashim(Executive Officer, Director)

BoardMir Imran(Executive Officer, Director)Andrew Farquharson(Director)

Co-investorsVHM

Neptune Medicalneptunemedical.comin✓ verified

Neptune Medical is a medical device company developing GI endoscopy products based on its Dynamic Rigidization technology, including the FDA-cleared Pathfinder endoscope and the Triton robotic endoscopy system for colon navigation.

HealthtechMedical DevicesRoboticsSilicon Valley, US

Alex Tilson(Founder & CEO)

Co-investorsSonder CapitalMighty CapitalShangBay Capital LLC

Cardiac Pathwaysacquired by Boston Scientific

Pioneered endocardial mapping and ablation technologies for cardiac arrhythmias; acquired by Boston Scientific.

Corhythm

Early-stage company developing a novel therapy for atrial fibrillation.

Entrack

Developing novel treatments for gastrointestinal disorders including Crohn's disease and ulcerative colitis.

Fe3

Early-stage company developing a novel transdermal therapy for iron deficiency anemia.

Fe3 Medical
iBridge

Developing a remote patient monitoring system to wirelessly manage patients with active implants.

IntraPace

Developing a gastric stimulation product platform (abiliti) for the treatment of obesity.

Neurolink

Early-stage company developing a novel therapy for the treatment of epilepsy.

NFocusacquired by Covidien

Developed the LUNA embolization device for brain aneurysms; acquired by Covidien (then Medtronic).

Percusurgeacquired by Medtronic

Pioneered embolic protection in interventional cardiology with its Guardwire product; acquired by Medtronic.

Physiometrixacquired by Hospira

Developed neuro-diagnostic devices including depth-of-anesthesia sensors; went public in 1996 and later acquired by Hospira.

Python

Developing innovations for gastrointestinal disorders, including post-surgical leak resolution and bioresorbable healing devices.

Rani

Developing a disruptive technology for oral delivery of biologics.

Co-investorsSamsara BioCapital

SacraMed

Medical technology company developing a neuromodulation system to treat overactive bladder (OAB).

SafeViewacquired by L-3 Communications

Developed mm-wave radar imaging technology for homeland security screening; acquired by L-3 Communications in 2006.

Symic Biomedical

BiotechSan Francisco, US

KENNETH N. HORNE(Executive Officer, Director)KATE STUART(Executive Officer)ALYSSA PANITCH(Director)JOHN PADERI(Director)

Co-investorsMitsui Global InvestmentAlly Bridge GroupLilly Ventures

Theracletheracle.com

A medtech company developing a platform focused on treating neurological conditions and neurotherapeutics.

Deep TechHealthtechMedical Devices

Vidamedacquired by Medtronic

Developed a non-surgical transurethral needle ablation therapy for benign prostatic hyperplasia; acquired by Medtronic.

Zonareacquired by Mindray

Developed compact ultrasound systems using Zone Sonography imaging; acquired by Mindray.

Co-investorsApposite Capital

Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.

Exits · 9

IPOs and acquisitions across the tracked portfolio

Rani Therapeutics HoldingsNASDAQ: RANIRani TherapeuticsNASDAQ: RANICardiac Pathwaysacq. by Boston ScientificNFocusacq. by CovidienPercusurgeacq. by MedtronicPhysiometrixacq. by HospiraSafeViewacq. by L-3 CommunicationsVidamedacq. by MedtronicZonareacq. by Mindray

Portfolio news

latest coverage across their companies

Frequently asked questions

How many investments has InCube Ventures made?
InCube Ventures has 19 tracked investments, 7 of which have exited via acquisition or IPO.
What stage does InCube Ventures invest at?
InCube Ventures invests at the Seed, Series A, Late Stage stages.
What sectors does InCube Ventures focus on?
InCube Ventures focuses on Biotech, Healthtech, Medical Devices.
Where is InCube Ventures located?
InCube Ventures is headquartered in San Jose, US.

Images

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