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InCube Ventures

Venture studio

San Jose · Seed–Late Stage · 3 people tracked

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Investment thesis

InCube Labs is a life sciences innovation lab, not the expected InCube Ventures firm. It identifies major unsolved clinical problems in healthcare and develops novel therapies, spinning research projects into portfolio companies for product development, clinical trials, regulatory approval, and commercialization. Focus areas span urology, gastroenterology, women's health, CNS disorders, musculoskeletal conditions, metabolic diseases, and cancer, often via implantable devices, drug-delivery combinations, and biomaterials. It collaborates with affiliated entities InCube Ventures, VentureHealth, and Modulus for funding and manufacturing support.

Source: firm website, verified Aug 2, 2026.

Stage
Seed–Late Stage
HQ
San Jose, TX, US
Instruments
Equity
Founded
1995
Last 12 months
1 investment
AUM
$125M
Tracked investments
23

Team · 3 people

from the firm's website

What they invest in

from 6 of 23 portfolio companies

Biotech ×4Medical Devices ×4Healthtech ×3Deep Tech ×2Digital Health ×1Robotics ×1

HQs:United States×5

Investments · 23 tracked

founders shown can be your intro path
Rani Therapeutics HoldingsNASDAQ: RANIOct 2025SEC filingmedium confidence

BiotechSan Jose, US

Talat Imran(Executive Officer, Director)inSvai Sanford(Executive Officer)inMir Hashim(Executive Officer)in

BoardAbraham Bassan(Director)Vasudev Bailey, M.D.(Director)

Board seatMir Imran· per SEC Form D · $60.3M raise · filed Nov 2025

Co-investorsRA Capital

Rani Therapeuticsranitherapeutics.cominNASDAQ: RANI

Rani Therapeutics develops oral drug delivery technology using robotic capsules to replace injectable biotherapeutics, addressing the challenge of delivering biologics through the gastrointestinal tract without needles.

BiotechDigital HealthHealthtechMedical DevicesSan Jose, US

Mir Hashim(Executive Officer, Director)in

BoardMir Imran(Founder)Andrew Farquharson(Director)

Co-investorsRA CapitalVHM

Neptune Medicalneptunemedical.comin✓ verified

Neptune Medical is a medical device company developing GI endoscopy products based on its Dynamic Rigidization technology, including the FDA-cleared Pathfinder endoscope and the Triton robotic endoscopy system for colon navigation.

HealthtechMedical DevicesRoboticsSilicon Valley, US

Alex Tilson(Founder & CEO)in

Co-investorsSonder CapitalMighty CapitalShangBay Capital LLC

Cardiac Pathwaysacquired by Boston Scientific

Pioneered endocardial mapping and ablation technologies for cardiac arrhythmias; acquired by Boston Scientific.

Corhythm

Early-stage company developing a novel therapy for atrial fibrillation.

Entrack

Developing novel treatments for gastrointestinal disorders including Crohn's disease and ulcerative colitis.

Fe3

Early-stage company developing a novel transdermal therapy for iron deficiency anemia.

Fe3 Medical
iBridge

Developing a remote patient monitoring system to wirelessly manage patients with active implants.

IntraPace

Developing a gastric stimulation product platform (abiliti) for the treatment of obesity.

Metagenomimetagenomi.coin𝕏

Metagenomi Therapeutics is an in vivo genome editing company that uses genetic material sourced from natural environments (metagenomics) to develop a toolbox of editing tools for deletion, integration, and correction of genetic mutations.

BiotechDeep TechMedical DevicesBerkeley, US

Brian Thomas(Executive Officer, Director, Promoter)in

BoardAndrew Farquharson(Director)Jak Knowles(Director)

Co-investorsCatalio Capital Management, LPRA CapitalSozo VenturesAgent CapitalFrazier Life SciencesHumboldt+5 more

Neurolink

Early-stage company developing a novel therapy for the treatment of epilepsy.

NFocusacquired by Covidien

Developed the LUNA embolization device for brain aneurysms; acquired by Covidien (then Medtronic).

Percusurgeacquired by Medtronic

Pioneered embolic protection in interventional cardiology with its Guardwire product; acquired by Medtronic.

Physiometrixacquired by Hospira

Developed neuro-diagnostic devices including depth-of-anesthesia sensors; went public in 1996 and later acquired by Hospira.

Python

Developing innovations for gastrointestinal disorders, including post-surgical leak resolution and bioresorbable healing devices.

Rani

Developing a disruptive technology for oral delivery of biologics.

Co-investorsSamsara BioCapital

SacraMed

Medical technology company developing a neuromodulation system to treat overactive bladder (OAB).

SafeViewacquired by L-3 Communications

Developed mm-wave radar imaging technology for homeland security screening; acquired by L-3 Communications in 2006.

Symic Biomedical

Biotechnology company developing therapeutics that target the extracellular matrix in acute and chronic diseases.

BiotechSan Francisco, US

KENNETH N. HORNE(Executive Officer, Director)ALYSSA PANITCH(Director)JOHN PADERI(Director)KATE STUART(Executive Officer)

Co-investorsMitsui Global InvestmentAlly Bridge GroupLilly Ventures

Theracletheracle.com

A medtech company developing a platform focused on treating neurological conditions and neurotherapeutics.

Deep TechHealthtechMedical Devices

Vidamedacquired by Medtronic

Developed a non-surgical transurethral needle ablation therapy for benign prostatic hyperplasia; acquired by Medtronic.

Zonareacquired by Mindray

Developed compact ultrasound systems using Zone Sonography imaging; acquired by Mindray.

Co-investorsApposite Capital

Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.

Exits · 9

IPOs and acquisitions across the tracked portfolio

Rani Therapeutics HoldingsNASDAQ: RANIRani TherapeuticsNASDAQ: RANICardiac Pathwaysacq. by Boston ScientificNFocusacq. by CovidienPercusurgeacq. by MedtronicPhysiometrixacq. by HospiraSafeViewacq. by L-3 CommunicationsVidamedacq. by MedtronicZonareacq. by Mindray

Portfolio news

latest coverage across their companies

Frequently asked questions

How many investments has InCube Ventures made?
InCube Ventures has 19 tracked investments, 7 of which have exited via acquisition or IPO.
What stage does InCube Ventures invest at?
InCube Ventures invests at the Seed, Series A, Late Stage stages.
What sectors does InCube Ventures focus on?
InCube Ventures focuses on Biotech, Healthtech, Medical Devices.
Where is InCube Ventures located?
InCube Ventures is headquartered in San Jose, US.

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