Lifeforce Capital
Venture capitalChevy Chase · Seed–Series C · 3 people tracked
Also known as LIFEFORCE CAPITAL MANAGEMENT, LLC
Investment thesis
Lifeforce Capital focuses on backing software companies aiming to reshape and modernize the status quo within healthcare's largest markets.
Source: firm website, verified Aug 25, 2026.
Team · 3 people
from public directoriesWhat they invest in
from 43 of 50 portfolio companiesHealthtech ×34Digital Health ×26Biotech ×19AI & Machine Learning ×17Medical Devices ×16Deep Tech ×10Mental Health ×6Wellness & Fitness ×4
HQs:United States×30United Kingdom×1
Who they back
founder profiles across 33 portfolio companiesFounding team size:solo founder×152 founders×93 founders×64+ founders×3
Where their founders studiedfrom 16 founders with education data
University of Cambridge ×3Yale University ×3Harvard University ×2University of California, Berkeley ×2
Where their founders worked beforefrom 20 founders with career history
Google ×2Harvard Medical School ×2Skadden, Arps, Slate, Meagher & Flom LLP and Affiliates ×2Stanford University ×2University of California, San Francisco ×2
Accelerator rootsportfolio companies that came through a program
Investments · 50 tracked
founders shown can be your intro pathBy year:2026 · 12024 · 12021 · 22020 · 22019 · 17 dated
Heartflow provides an AI-based analysis that converts a coronary CTA scan into a personalized 3D model of the heart, assessing anatomy and physiology to help diagnose and manage coronary artery disease (CAD).
AI & Machine LearningBiotechDigital HealthHealthtechMedical DevicesRedwood City, US
Christopher K. Zarins(Executive Officer, Director)Charles A. Taylor(Executive Officer, Director)Nicky Espinosa Hayes(Executive Officer)John Stevens(Executive Officer, Director)H. Baird Radford, III(Executive Officer)John Farquharin
Co-investorsBain Capital Life SciencesBlue Venture FundsEmergent Medical Partners, LLPKhosla VenturesLotus CapitalSilver Lake Partners+1 more
Senti Bio develops cell and gene therapies for cancer and difficult-to-treat diseases using synthetic biology and engineered Gene Circuits to enhance precision, control, and selectivity in targeting tumor cells.
BiotechDeep TechMedical DevicesSouth San Francisco, US
Tim Lu(Co-Founder and Chief Executive Officer)inPhilip Lee(Executive Officer)Kanya Rajangam(President, Head of Research & Development and Chief Medical Officer)Yvonne Li(Executive Officer)James Collins(Director)
BoardDonald Tang(Director)
Co-investorsEvolution VC PartnersFlucas VenturesLux CapitalMenlo VenturesNew Enterprise Associates (NEA)NSG Ventures+2 more
Aspen Neuroscience develops iPSC-derived autologous cell therapies for neurological diseases, with a lead product (ANPD001) in Phase 1/2a clinical trials for Parkinson's disease.
BiotechDeep TechDigital HealthMedical Devices
Andrés Bratt-Leal(Co-Founder and Senior Vice President, Research & Development)Damien McDevitt(President and Chief Executive Officer)
Co-investorsARCH Venture PartnersOrbiMedDomain AssociatesEDB InvestmentsSection 32Frazier Life Sciences+3 more
64x develops infrastructure and manufacturing systems for next-generation medicines, focusing on genetic engineering, cell line development, and computational biology to enable scalability of advanced therapies.
AI & Machine LearningBiotechDeep TechHealthtechMedical DevicesSan Francisco, US
Lexi Rovner(Co-founder & CEO)in
Co-investorsFifty YearsFuture VenturesRaptor GroupY CombinatorRefactor Capital
Able Health provides software for physician organizations to administer value-based care programs, including quality measure calculation and health plan coordination to reduce administrative overhead.
HealthtechSan Francisco, US
Rachel Katz(Founder/CEO)inSteve Daniels(Founder/President)in
Co-investorsY CombinatorRefactor Capital
Nashville-based provider of home and outpatient community-based palliative care for seriously ill patients, acquired by Anthem in 2018.
Digital HealthHealthtechNashville, US
Brad Smith(Executive Officer, Director)Andrew Lasher(Executive Officer)Diane Seloff(Executive Officer)William Frist(Director)William Anderson(Executive Officer)
BoardAnn Lamont(Director)
Co-investorsFrist Cressey VenturesGV (Google Ventures)Mountain Group CapitalOak HC/FT
Bayesian Health develops clinical artificial intelligence for real-time patient monitoring and clinical decision support.
AI & Machine LearningDigital HealthHealthtechMedical Devices
Dr. Suchi SariaSuchi Saria(Founder and CEO)in
Co-investorsAndreessen HorowitzCatalio Capital Management, LPEpsilon Health InvestorsHealth2047 Capital Partners LLCMemorialCare Innovation Fund
Carecube is a medical device developed for hospitals, emergency responders, and care settings to support infectious disease response and preparedness.
HardwareHealthtechMedical Devices
Co-investorsSchooner CapitalVery Serious Ventures
Character Bio is a precision medicine company that integrates genomics, longitudinal clinical data, imaging, and AI-based biomarker analysis to identify genetic drivers of progressive polygenic eye diseases such as age-related macular degeneration and glaucoma.
AI & Machine LearningBiotechDigital HealthJersey City, US
Cheng Zhang(Executive Officer, Director)
BoardVivek Garipalli(Director)Nick Olsen(Director)Peter DiLaura(Director)
Co-investorsaMoonCantos VenturesCatalio Capital Management, LPDuke Capital PartnersSanofi VenturesCatalio Capital Management+3 more
Circle Pharma develops cancer treatments using macrocycle therapies designed to reduce side effects compared to conventional therapies.
BiotechDigital HealthHealthtechMedical DevicesSouth San Francisco, US
Matthew P. Jacobson(Co-founder)Scott R. Lokey(Director)Matthew Jacobson(Director)David J. Earp(President & CEO)Paul Park(Executive Officer)
BoardThilo Schroeder(Director)in
Co-investorsBerkeley CatalystMission Bay CapitalMission BiocapitalNextech InvestPandect BioventuresThe Column Group+1 more
Cityblock provides primary care and health services focused on making healthcare accessible as a basic right, particularly serving underserved and marginalized communities with an emphasis on trust-based, inclusive care.
Digital HealthHealthtechImpact & Social GoodMental HealthBrooklyn, US
Dr. Toyin Ajayi(Co-founder & CEO)Iyah Romm(Executive Officer, Director)Toyin Ajayi(Founder)inMat Balez(Founder)in
BoardAndy Slavitt(Director)inAmbar Bhattacharyya(Director)
Co-investors8VCEcho Health VenturesGeneral CatalystKinnevikMaverick VenturesOpen Opportunity Fund+4 more
Clover Health is a health insurance provider offering low-cost plans with minimal premiums, copays, and prescription drug costs.
Digital HealthHealthtechInsurTechJersey City, US
Vivek Garipalli(Executive Officer, Director)Andrew ToyinKris Gale(Executive Officer, Director)
BoardNat Turner(Director)Mike Dixon(Director)Josh Kopelman(Director)in
Co-investorsFirst Round CapitalFloodgateGV (Google Ventures)Toba CapitalRefactor CapitalSequoia Capital+1 more
Cricket Health provides value-based kidney care, using a holistic approach to treat people with chronic kidney disease and related cardiovascular conditions.
AI & Machine LearningDigital HealthHealthtechSan Francisco, US
Arvind Rajan(Executive Officer, Director)Dr. Carney Taylor(Chief Medical Officer)Dr. Terry Ketchersid(Senior Vice President, Medical Office)Dr. Julie Dominguez(Vice President, Medical Office)
BoardVincent Kim(Director)
Co-investorsNext Play VenturesNFX
Vivante Health offers a digital platform providing clinician-backed, personalized care for digestive and gastrointestinal health, covering issues from bloating and women's digestive health to chronic conditions like IBS and IBD.
Digital HealthHealthtechWellness & Fitness
Co-investorsCorewell Health VenturesMercato Partners
HealthtechGrand Cayman
Thomaz Srougi(Director)inJuan Carlos Moreno(Director)Luiz Claudio Nacimento(Director)Juan Vergara(Director)Renato Velloso(Director)
BoardHernan Kazah(Director)in
Co-investorsKaszek VenturesLightrock
Eko develops FDA-cleared digital stethoscopes and AI-powered software that enables healthcare professionals to detect and diagnose cardiovascular disease with greater accuracy.
AI & Machine LearningDigital HealthHealthtechMedical Devices
Connor Landgraf(Co-Founder and CEO)Tyler CrouchJason Bellet(Co-Founder and Chief Business Officer)in
Co-investorsQuesta CapitalHighland Capital PartnersArtis VenturesBetter Ventures Central LlcDigiTx Partners LLCEvolution VC Partners+7 more
Viswa Colluru, PhD(Founder)in
Co-investorsAir Street CapitalCatalio Capital Management, LPFPVHummingbird VenturesJAZZ Venture PartnersKinnevik+6 more
Fathom provides autonomous medical coding software for healthcare organizations, using AI to automate the assignment of medical codes.
AI & Machine LearningDigital HealthHealthtech
Co-investorsAlkeon InnovationGreat Oaks Venture CapitalInflect HealthMBX Capital
Fauna Bio applies AI and computational analysis to its proprietary biobank of data from extreme mammals such as hibernating species to identify drug targets that are conserved across species including humans.
AI & Machine LearningBiotechDeep TechHealthtechEmeryville, US
Linda Goodman(Founder)inAshley(CEO)
Co-investorsage1Farvatn VentureGRIDS CapitalMetaplanetVibe CapitalBeagle Ventures+3 more
Floreo builds a library of immersive VR lessons designed to help develop social and behavioral regulation skills.
Digital HealthEdTechHealthtech
Co-investorsCity LightColopl NextPresence Capital
Galileo operates a medical practice combining a technology platform with in-house primary and multi-specialty clinicians to provide accessible, lower-cost care.
Digital HealthHealthtech
Tom X Lee(Founder)
Co-investorsMcKesson VenturesOak HC/FTScale Venture PartnersVamosVenturesAmex VenturesBattery Ventures+6 more
Included Health provides healthcare navigation and delivery services—including care guidance, billing and claims support, and virtual and in-person care spanning primary, behavioral, urgent, and specialty care—for employees and members of health plans and employers.
Digital HealthHealthtechMental HealthSan Francisco, US
Owen Tripp(Co-Founder & CEO)inLawrence Hofmann(Co-Founder, Grand Rounds)Adam Jackson(Co-Founder, Doctor On Demand)Jay McGraw(Co-Founder, Doctor On Demand)Phil McGraw(Co-Founder, Doctor On Demand)Colin Quinn(Executive Officer, Director)
Co-investorsAdams Street PartnersAlpha PartnersB CapitalBlackRockFelicis VenturesGaingels+15 more
Iora Health was a primary care company focused on value-based care for Medicare-eligible seniors, operating clinics with a team-based model including health coaches.
Digital HealthHealthtechWellness & FitnessSan Francisco, US
RUSHIKA FERNANDOPULLE(Executive Officer, Director)CHRISTOPHER J. MCKOWN(Executive Officer, Director)DAVID FIELDING(Executive Officer)ALEXANDER PACKARD(Executive Officer)DAVID JUDGE(Executive Officer)
BoardSTEPHEN KNIGHT(Director)in
Co-investors.406 VenturesDag VenturesF-Prime CapitalFlare Capital PartnersGV (Google Ventures)Maverick Ventures+5 more
MindRight offers nonclinical emotional support delivered by text message, matching members with a personal emotional support partner drawn from their community for up to seven days a week of check-ins.
Digital HealthMental HealthWellness & Fitness
Co-investorsDigitalDx Ventures
BiotechWaltham, US
Brian Fiske(Executive Officer, Director)George Eliades(Executive Officer, Director)inSandra Poole(Executive Officer)Alex Nichols(Executive Officer, Director, Promoter)
BoardBryan Roberts(Director)Peter Hecht(Director)
Co-investorsHemi Ventures, LlcRefactor CapitalVenrock Associates
Notable Labs operates an automated laboratory that tests combinations of existing drugs against individual patients' blood cancer cells to identify effective treatment options for patients whose cancers have become resistant to standard therapies.
BiotechHealthtechMedical DevicesSan Francisco, US
Matthew De Silva(Founder/CEO)inPete Quinzio(Founder)in
Co-investors11.2 CapitalBuilders VCFundersClubHemisphere Ventures LLCY CombinatorAmplify Partners+3 more
Ochre Bio develops RNA therapeutics and drug discovery platforms targeting liver disease, combining proprietary human liver datasets with AI-driven causal prediction and human tissue validation models.
AI & Machine LearningBiotechHealthtechMedical DevicesLondon, GB
Quin Wills(Founder/CSO)inJack O'Meara(Founding CEO)in
BoardChinwe UkomaduElaine SullivanEliot ForsterJack Castle
Co-investorsBackedBeast VenturesCoastCapEntrepreneur FirstExpaHoxton Ventures+6 more
People Science runs real-world clinical research for the health and wellness industry, offering a decentralized clinical trial platform (Chloe Clinical) and a real-world data collection tool (Chloe LiveLab) alongside clinical research services.
Digital HealthHealthtechWellness & Fitness
Noah Craft(Founder)in
Co-investorsAcre Venture PartnersFTW VenturesNoeticBluestein VenturesSUPPLY CHANGE CAPITAL
Positive Development provides autism therapy and developmental care services for neurodivergent children and their families.
Digital HealthHealthtechMedical DevicesMental HealthMclean, US
Mike Suiters(Executive Officer, Director)Nick Whitehead(Director)
BoardAdam Seabrook(Director)inDaniel Gebremedhin(Director)John Banta(Director)Brenton Fargnoli(Director)in
Co-investorsAlleyCorpB Capital GroupB4 CapitalFlare Capital PartnersObvious VenturesAlley Robotics Ventures+2 more
Postera uses artificial intelligence and computational chemistry to accelerate drug discovery for pharmaceutical companies.
AI & Machine LearningBiotechDeep TechHealthtechMedical DevicesBoston, US
Aaron Morris(Founder)inAlpha Lee(Founder)inMatthew Robinson(Founder)in
Co-investorsBreyer CapitalHOF CapitalMetaplanetY CombinatorACE & Company
Reverie Labs develops cancer treatments designed to cross the blood-brain barrier and treat tumors in the central nervous system.
AI & Machine LearningBiotechHealthtechBoston, US
Ankit Gupta(Founder/CTO)inConnor Duffy(Founder)inJonah Kallenbach(Founder)in
Co-investorsDorm RoomRuvento Ventures Pte Ltd.Wireframe VenturesY CombinatorFirst Round CapitalNeo
Riva Health offers a program that measures and manages cardiovascular health using a smartphone.
Digital HealthHealthtechMedical Devices
Tuhin Sinha, PhD(Founder)in
Co-investorsBaruch Future VenturesTop Corner CapitalMenlo Ventures
Co-investorsPfizer Venture InvestmentsDigitalis Ventures
Sempre Health provides digital health solutions focused on patient engagement and outcomes management for the healthcare industry.
Digital HealthHealthtechColorado Springs, US
Anurati Mathur(Founder)inRobert S. Spalding(Executive Officer, Director)
BoardTyler Rowe(Director)Benjamin J. Doramus(Director)Kelsey Gorman(Director)
Co-investorsCencora VenturesCerity Partners VenturesEcho Health VenturesRethink ImpactSterling RoadIndustry Ventures
Serna builds a platform to unlock the transcriptome as a drug target for drug discovery.
AI & Machine LearningBiotechDeep TechHealthtechOntario, US
Rabia Khan(Founder)in
Co-investorsBackedHummingbird VenturesY Combinator
Sonoma Biotherapeutics develops engineered regulatory T cell therapies to treat autoimmune and inflammatory diseases.
BiotechHealthtechMedical DevicesSouth San Francisco, US
Jeffrey Bluestone(Executive Officer, Director, Promoter)
BoardFan Yu(Director)Maggie Wilderotter(Director)Toni Hoover(Director)Terry Rosen(Director)Richard Klausner(Director)
Co-investors8VCARCH Venture PartnersFrazier Life SciencesJDRF T1D FundLAVLilly Asia Ventures+1 more
Sunstone Therapies is a clinical research organization with expertise in psychedelic and consciousness research, operating with teams that include researchers from institutions like Johns Hopkins Center for Psychedelic and Consciousness Research and the Dana-Farber Cancer Institute.
BiotechDigital HealthHealthtechMedical DevicesMental HealthRockville, US
Manish Agrawal(CEO)inKimberly Roddy(Executive Officer, Director)Paul Thambi(Executive Officer, Promoter)
BoardRiaz Valani(Director)Omar Njie(Director)in
Co-investorsAlleyCorpAlley Robotics Ventures
Synapticure provides virtual care services for individuals and families with neurodegenerative conditions, offering access to expert-led care, cutting-edge treatments, clinical trials, and wraparound support across all 50 US states through a network of local partners.
AI & Machine LearningDigital HealthHealthtechChicago, US
Peter Wallach(Founding CEO, Founder)Brian Wallach(Founder)inMartina de Majo(Founder)inSandra Abrevaya(Co-Founder, Chief Executive Officer)Jason Langheier(Co-Founder, Board Co-Chair)Jaimie Hatcher-Martin(Dr.)
Co-investorsGeneral AtlanticSV AngelB Capital GroupB4 CapitalCVS Health VenturesMartin Ventures+2 more
Valo builds an AI-driven drug discovery and development platform that combines real-world human data, causal inference, statistical genetics, and predictive chemistry to identify disease targets and engineer small-molecule compounds.
AI & Machine LearningBiotechDeep Tech
Co-investorsTachyon Ventures
Topography Health operated a site business unit that was acquired by FOMAT Medical Research.
Medical DevicesWilmington, US
N. Alexander Saint-Amand(Executive Officer, Director, Promoter)Alexander Saint-Amand(Founder)Andrew P. Kirchner(Executive Officer, Director, Promoter)Joshua M. Parish(Executive Officer, Director, Promoter)
Co-investorsAndreessen HorowitzValspring Capital75 & SunnyBain Capital Ventures
Transition Bio applies methods from physics, chemistry, biology, and machine learning to study protein biophysics—including protein aggregation, self-assembly, and protein-protein interactions—for developing therapeutics targeting health and disease.
AI & Machine LearningBiotechDeep TechCambridge, US
Tuomas Knowles(Executive Director, Co-Founder & Chief Technology Officer)Samuel Cohen(Executive Director & Co-Founder)G. Kelly Martin(Executive Chairman & Co-Founder)George Martin(Executive Officer, Director)Stephanie Torruella(Executive Officer)Preet Makkar(Executive Officer)
Co-investorsNorthpond VenturesMagnetic VenturesTaiho Ventures, LLCDolby Family Ventures
Verge Labs builds AI models trained on multimodal human patient data to predict drug targets and patient populations for clinical development, primarily in neuroscience and central nervous system (CNS) disease.
AI & Machine LearningBiotechDeep TechDigital HealthHealthtechSan Francisco, US
Alice Zhang(Founder/CEO)inJason Chen(Cofounder)Emily Ripka(Head of Product & Engineering)
Co-investorsBOLD LongevityDraper AssociatesFitz Gate VenturesGreat Oaks Venture CapitalKarlin VenturesTenmile+5 more
Wavebreak is a biotech company developing a drug discovery platform that uses biophysics to target transient toxic protein oligomers in amyloid disease pathways with small-molecule drugs.
BiotechDeep TechHealthtech
Co-investorsSchooner Capital
Zing Health offers Medicare Advantage health insurance plans, providing members with coverage tools including a mobile app, member portal, provider search, and prescription cost estimator.
Digital HealthHealthtechInsurTech
Co-investorsHealth2047Health2047 Capital Partners LLC
Exits · 4
IPOs and acquisitions across the tracked portfolioHeartFlowNASDAQ: HTFLSenti BiosciencesNASDAQ: SNTIAspire Healthacq. by CareMore Health (Anthem)Iora Healthacq. by One Medical
Portfolio news
latest coverage across their companiesHeartFlow · seekingalpha.com · Aug 16, 2026
Cylinder Health · fiercehealthcare.com · Aug 5, 2026
Senti Biosciences · kalkine.com.au · Jul 31, 2026
Included Health · PE Hub · Jul 29, 2026
64x Bio · businesswire.com · Jun 29, 2026
Carecubes · tipranks.com · Jun 3, 2026
PostEra · cen.acs.org · Jun 2, 2026
Frequently asked questions
- How many investments has Lifeforce Capital made?
- Lifeforce Capital has 50 tracked investments, 6 of which have exited via acquisition or IPO, including 2 dated in the last 24 months.
- What stage does Lifeforce Capital invest at?
- Lifeforce Capital invests at the Seed, Series A, Series B, Series C stages.
- What is Lifeforce Capital's typical check size?
- Lifeforce Capital typically writes checks of $500K – $5M.
- What sectors does Lifeforce Capital focus on?
- Lifeforce Capital focuses on Digital Health, Healthtech, SaaS.
- Where is Lifeforce Capital located?
- Lifeforce Capital is headquartered in Chevy Chase, US.
- Does Lifeforce Capital lead rounds?
- Lifeforce Capital typically participates in rounds rather than leading them.
- Who does Lifeforce Capital co-invest with?
- Lifeforce Capital most often shares deals with Y Combinator, GV (Google Ventures), Catalio Capital Management, LP, among 162 tracked co-investors.
Co-investors · 6
Entrepreneur First (EF) is a talent investor that helps individuals build and launch startups, providing support such as US visa guidance, office space, fundraising preparation, and investor introductions culminating in a San Francisco Demo Day.
Builders VC is a venture firm run by operators and investors that backs founders solving complex, mission-critical problems in industries dominated by legacy systems.
Industry Ventures is an investment firm founded in 2000 that provides flexible capital solutions across the venture life cycle, from seed and early-stage investing to late-stage secondaries and tech buyouts of VC-backed companies.
KdT Ventures is an early-stage venture firm investing in frontier science and technology startups, backing founders building platforms that engineer matter, energy, and information across biology, chemistry, physics, and computation.
Lookout Ventures provides seed-stage funding to enterprise technology companies outside Silicon Valley, with partner expertise in AI, cybersecurity, infrastructure software, and vertical SaaS.
Bija invests in computationally-enabled therapeutic platforms, supporting biotech companies from development candidate stage through first-in-human trials.
Firms observed investing alongside Lifeforce Capital, from public investor directories. Shared companies are the overlap with Lifeforce Capital's recorded portfolio.
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