Fundraising Fox

AME Cloud Ventures

Venture capital

Palo Alto · Seed–Late Stage · 10 people tracked

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Investment thesis

AME Cloud Ventures backs seed to later stage companies building infrastructure and value chains around data. It favors technology-heavy startups that gather or create unique data across every layer of the data stack — from infrastructure through applications, mobile, and sensors. The firm believes advances in data, cloud, and hardware create major opportunities to build great companies, and it centers its approach on backing exceptional entrepreneurs. Beyond capital, AME offers operational and business experience plus networks of mentors and international partners, with particular strength in China and Asia.

Source: firm website, verified Aug 3, 2026.

Stage
Seed–Late Stage
Check
$1M – $10M
HQ
Palo Alto, California, US
Leads rounds
Leads
Instruments
Equity
Founded
2012
Tracked investments
31

Team · 10 people

from the firm's website & public directories
Wretch Chien· Principalin𝕏
Nick Adams· Venture Partnerin𝕏

What they invest in

from 23 of 31 portfolio companies

AI & Machine Learning ×15Biotech ×11Deep Tech ×8Healthtech ×8Medical Devices ×6Data & Infrastructure ×5Digital Health ×4Enterprise Software ×4

HQs:United States×23

Investments · 31 tracked

founders shown can be your intro path
Freenomefreenome.cominNASDAQ: FRNM

Freenome develops early-stage cancer detection technology using blood tests to identify cancer in its earliest, most treatable phases.

AI & Machine LearningBiotechDigital HealthHealthtechMedical DevicesLondon

Riley Ennis(Co-Founder and Chief Product Officer)Stuart Lawson(Director)Charles Roberts(Director)Gabriel Otte(Director)

Nautilus Biotechnologynautilus.bioin𝕏NASDAQ: NAUT

Nautilus develops proteomics technology to unlock the complexity of the human proteome for biomedical research and diagnostics.

BiotechDeep TechMedical DevicesSeattle, US

Sujal Patel(Founder & CEO)inParag Mallick(Founder & Chief Scientist)inMelissa Epperly(Director)inNicholas Nelson(Executive Officer)Subra Sankar(Executive Officer)Farzad Nazem(Director)in

Vicarious SurgicalOTC: RBOT

HealthtechWaltham, US

Joseph Doherty(Director)David Ho(Director)Adam Sachs(President)Stephen From(Chief Executive Officer)Beverly Huss(Director)Fuad Ahmad(Director)

Accion Systems

Boston, US

Robert Smith(Executive Officer)Natalya Brikner(Executive Officer, Director)

BoardDarren Garber(Executive Officer, Director)Danil Subkhankulov(Director)Robert Kaemmerer(Director)Greg Nixon(Director)

Asimovtryasimov.aiin𝕏

Asimov collects real-world human activity data at scale from diverse environments to create annotated datasets for training robotics AI models.

Advanced ManufacturingAI & Machine LearningData & InfrastructureRoboticsSan Francisco, US

Lyem Ningthou(Founder)in

Asimovasimov.comin𝕏

Asimov develops a computer-aided design platform for genetic engineering, enabling designers to program living cells by applying abstraction, standardization, and modeling to biology.

AI & Machine LearningBiotechDeveloper ToolsBoston, US

Chris Voigt(Co-founder)Doug Densmore(Co-founder)Alec Nielsen(Co-founder & CEO)Raja Srinivas(Co-founder)

Asimovasimov.ioin𝕏

Asimov builds a computer-aided design platform for genetic engineering and synthetic biology, enabling genetic designers to program living cells through automated circuit design and computational modeling.

AI & Machine LearningBiotechDeep TechBoston, US

Chris Voigt(Co-founder)Doug Densmore(Co-founder)Alec Nielsen(Co-founder & CEO)Raja Srinivas(Co-founder)

BigHat Biosciencesbighatbio.comin𝕏

Big Hat Bio develops therapeutics under development across multiple programs.

AI & Machine LearningBiotechDeep TechSan Francisco, US

Peyton Greenside(Executive Officer, Director)Steve Kafka(Director)Vineeta Agarwala(Director)Robert Chess(Director)Mark DePristo(Executive Officer, Director)

BoardFrancisco Gimenez(Director)

Calacala.aiin

Cala provides verified, structured data from public sources including financial filings, market data, regulatory information, news, and business registries to AI agents and applications through an API.

AI & Machine LearningData & InfrastructureEnterprise Software

Calacalahealth.comin

Cala Health develops non-invasive prescription therapies for movement disorders, starting with a treatment for hand tremor and essential tremor.

Deep TechDigital HealthHealthtechMedical DevicesSilicon Valley, US

Kate Rosenbluth, PhD(President & Chief Innovation Officer)Deanna Harshbarger(Chief Executive Officer)

Canvas Technology
Capella Spacecapellaspace.comin𝕏

Palo Alto, US

Payam Banazadeh(Executive Officer, Director)William Woods(Director)Chris Boshuizen(Director)Nabeel Hyatt(Director)

Cleanlabcleanlab.ai

Cleanlab develops machine learning tools for data quality and model improvement, serving enterprises and ML practitioners across industries.

AI & Machine LearningData & InfrastructureDeveloper ToolsEnterprise SoftwareSaaS

Curtis NorthcuttinJonas Mueller(Co-founder)inAnish AthalyeinAnishathalye(Co-founder)Ulyana Tkachenko(Co-founder)in

Code Fourcodefour.usin𝕏

Code Four develops AI-powered investigation software for police departments that automates evidence processing and fuses data from body-worn cameras, records management systems, phone dumps, recorded audio, and case files.

AI & Machine LearningGovTechSan Francisco, US

George Cheng(Founder)inDylan Nguyen(Founder)in

CrowdAIcrowdai.comin𝕏

CrowdAI provides a no-code platform that enables organizations to build and deploy computer vision applications without requiring deep technical expertise.

AI & Machine LearningEnterprise SoftwareSan Francisco, US

Devaki Raj(Founder/CEO)inNic Borensztein(Founder/CTO)inPablo Garcia(Founder)inMohammad Islam(Director)

Elegenelegenbio.comin𝕏

Elegant Bio develops DNA synthesis technology and services, offering ENFINIA™ DNA synthesis at scale for biotech and research applications.

BiotechDeep TechSan Carlos, US

Matthew Hill(Executive Officer, Director)Peter Zhou(Director)Jonathan Sheena(Director)Cain McClary(Director)

Elementum
Endpoint Healthendpointhealth.comin𝕏

Endpoint Health develops immunology-focused therapeutics paired with diagnostic tests designed to match individual patients with treatments suited to their biology for critical and chronic illnesses.

BiotechHealthtechSan Francisco, US

Diego Rey(Founder/CSO)inJeff Osborn(Founder)Jason Springs(Founder)inLeonardo Teixeira(Founder)in

Geopipegeopipe.aiin

Geopipe creates digital twin technology that generates immersive 3D models of real-world cities and environments for use in games, simulations, training, and architecture.

AI & Machine LearningData & InfrastructureDeep TechGamingNew York City, US

Christopher Mitchell(CEO and Co-Founder)Thomas Dickerson(CSO and Co-Founder)Dickerson Dickerson(Executive Officer, Director, Promoter)Joshua Duyan(Director)

Holbertonin𝕏

EdTechSan Francisco, US

Julien Barbier(Executive Officer, Director)Sylvain Kalache(Former Director)Eustache Besancon(Director)Marie Ekeland(Director)Manoel Lemos(Director)Marc Verstaen(Director)

Inscopixinscopix.com

Inscopix develops advanced microscopy and neural circuit analysis technologies to understand brain function and disease mechanisms for neuroscience research.

AI & Machine LearningBiotechDeep TechMedical DevicesMountain View, US

Kunal Ghosh(Founder & CEO)Abbas El Gamal(Co-founder & Director)Mark Schnitzer(Scientific Cofounder & Board Observer)

MegaBots

Hayward, US

Guilherme Cavalcanti(Executive Officer, Director)Matthew Oehrlein(Executive Officer, Director)Joshua Adler(Director)

Nervana Systems
Osaroosaro.comin𝕏

OSARO designs AI-powered robotic systems for warehouse automation and fulfillment.

AI & Machine LearningLogistics & Supply ChainRoboticsSan Francisco, US

Scott Banister(Director)Michael Kahane(Executive Officer, Director)inDerik Pridmore(Executive Officer, Director)in

Osmindosmind.orgin𝕏

Osmind is a public benefit corporation developing technology and research infrastructure to accelerate evidence-based mental health treatments, including therapies like ketamine, and to improve patient access to care.

AI & Machine LearningBiotechDigital HealthHealthtechMedical DevicesMental HealthSaaSSan Francisco, US

Lucia Huang(Founder)inJimmy Qian(Founder)in

Pepperdatapepperdata.comin𝕏

Pepperdata provides real-time, automated resource optimization software for data workloads running on Kubernetes and YARN, helping enterprises reduce infrastructure costs by up to 30% without manual intervention.

Cloud ComputingData & InfrastructureDeveloper ToolsEnterprise SoftwareSaaSSilicon Valley, US

SEAN A. SUCHTER(Executive Officer, Director)ANDY LUDWICK(Director)PETER WAGNER(Director)CHARLES C. CARSON, JR.(Executive Officer, Director)ED CLUSS(Director)

Rigetti Quantum Computing
Savioke

Deploys autonomous service robots.

Synthegosynthego.comin𝕏

Synthego provides CRISPR genome engineering products and solutions at scale, supporting research and therapeutic development from discovery through clinical applications.

BiotechDeep TechHealthtechRedwood City, US

Paul John Dabrowski(Executive Officer, Director)Michael Jakub Dabrowski(Executive Officer, Director)Drew Oetting(Director)Scott Nolan(Director)

Transcriptictranscriptic.comin𝕏

Strateos operates a cloud lab platform offering laboratory automation-as-a-service, using high-throughput robotics that let scientists design, run, and analyze experiments remotely via a web browser.

AI & Machine LearningBiotechHealthtechRoboticsSan Francisco, US

Max Hodak(Founder/CEO)in

Viz Aiviz.aiin𝕏

Viz.ai uses artificial intelligence to accelerate care coordination in healthcare settings, reducing delays between patients and life-saving treatments.

AI & Machine LearningDigital HealthHealthtechMedical DevicesPalo Alto, US

Chris Mansi(Co-founder)David Golan(Co-founder)DROR BERMAN(APPOINTMENT EFFECTIVE UPON THIS FINANCING.)MICHAEL O'DONNELL(Executive Officer)

Frequently asked questions

What stage does AME Cloud Ventures invest at?
AME Cloud Ventures invests at the Seed, Series A, Series B, Series C, Growth, Late Stage stages.
What is AME Cloud Ventures's typical check size?
AME Cloud Ventures typically writes checks of $1M – $10M.
What sectors does AME Cloud Ventures focus on?
AME Cloud Ventures focuses on AI & Machine Learning, Cloud Computing, Data & Infrastructure, Deep Tech, Hardware, IoT, Medical Devices, Robotics, Space Tech.
Where is AME Cloud Ventures located?
AME Cloud Ventures is headquartered in Palo Alto, US.
Does AME Cloud Ventures lead rounds?
Yes, AME Cloud Ventures leads investment rounds.

Media · Podcasts & interviews

featuring the team

Journey to AME Cloud Ventures and Meeting Jerry Yang

Glasp · Jerry Yang

Co-investors · 182

Andreessen Horowitz

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$500K – $50M
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Both backed · 4
$5M – $25M
GV (Google Ventures)

GV (formerly Google Ventures) is a venture investment firm that backs founders across many industries, aiming to build long-term relationships and support companies across multiple stages and milestones.

Both backed · 2
$250K – $50M
Menlo Ventures

Menlo Ventures is a venture capital firm that backs transformative, early-stage technology companies reshaping how people live and work.

Both backed · 2
$1M – $20M
General Catalyst

General Catalyst is a venture capital and investment firm that backs founders across industries, with a strong focus on AI-driven transformation, fintech, healthcare, and other sectors.

Both backed · 1
$30M
Founders Fund

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Both backed · 1
$500K – $5M
Khosla Ventures

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Both backed · 1
$5K – $50M
Techstars

Techstars is a startup accelerator and early-stage investor that funds ambitious founders and provides capital, mentorship, and access to a global network of investors, operators, and corporate partners.

Both backed · 1
$220K
Kleiner Perkins

Kleiner Perkins is a venture capital firm that backs founders across technology and life sciences, with a portfolio of companies from early stage through growth.

Both backed · 1
$500K – $15M
Canaan Partners

Canaan is an early-stage venture capital firm backing founders with transformative ideas across technology and healthcare.

Both backed · 1
$500K – $20M
Tiger Global Management

Tiger Global is a research-driven investment firm that partners with innovative, high-quality companies over the long term across various stages of their lifecycle.

Both backed · 1
$1M – $100M
Susa Ventures

Susa Ventures operates two early-stage technology funds that invest in companies leveraging data, network effects, and economies of scale.

Both backed · 1
$1M – $5M
170 more co-investors

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Firms observed investing alongside AME Cloud Ventures, from public investor directories. Shared companies are the overlap with AME Cloud Ventures's recorded portfolio.

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