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AME Cloud Ventures

Palo Alto ยท Seedโ€“Late Stage ยท 5 people tracked

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Investment thesis

AME Cloud Ventures believes that data, cloud, and hardware advances will drive significant value creation. The firm seeks technology-heavy companies gathering or creating unique data at every stage of the data stack, from infrastructure through applications, mobile, and sensors. The firm emphasizes identifying and supporting true entrepreneurs with strong operational support, business expertise, and networks extending into Asia and China.

Source: firm website, verified Jul 20, 2026.

Stage
Seedโ€“Late Stage
HQ
Palo Alto, US
Founded
2012
Tracked investments
29

Team ยท 5 people

from the firm's website
Jerry Yangยท Founder & Co-Founder

Co-founder of Yahoo! in 1995 who served on its Board and executive team until 2012. Yang built Yahoo's relationships with Yahoo! Japan and Alibaba, and is a thought leader in China and Asia. He currently sits on the Board of Directors for Workday and Alibaba.

Jeffยท Investment Partner

Jeff joined AME Cloud Ventures in 2013 and is focused on empowering companies in frontier technologies spanning manufacturing, biology, infrastructure, and consumer experiences. Prior to AME, he was a growth stage investor at Silver Lake and earned his BS from UC Berkeley and MBA from Harvard. He sits on the Board for Savioke, an autonomous service robot company.

Wretchยท Investment Partner

Wretch joined AME Cloud Ventures in 2014 and is drawn to white space innovators in large markets without established competitors, such as aerospace, intelligent robotics, and next-generation medical devices. He previously founded and led wretch.cc, Taiwan's first and largest blogging platform serving 6 billion page views monthly before its acquisition by Yahoo!, and earned his MBA from Stanford.

Nickยท Venture Partner

Nick joined AME Cloud Ventures in 2012 and has a technical background focused on automation, machine learning, and software-defined infrastructure. He previously spent five years in China and India leading business development for Cloud Valley and founding two startups. He earned his Masters in Engineering from Imperial College and as of 2020 stepped back from investing in new companies while remaining with the firm.

Cathyยท Operations Manager

Cathy manages the firm's operations, organizes special events, and assists in portfolio activities. She previously spent nine years at Yahoo! as a Senior Executive Administrator supporting Jerry Yang. She earned her Bachelors degree from San Francisco State University.

What they invest in

from 19 of 29 portfolio companies

AI & Machine Learning ร—13Biotech ร—9Deep Tech ร—7Data & Infrastructure ร—5Healthtech ร—5Medical Devices ร—5Enterprise Software ร—4Developer Tools ร—3

HQs:United Statesร—13

Investments ยท 29 tracked

founders shown can be your intro path
Accion Systems
Asimovtryasimov.aiin๐•

Asimov collects real-world human activity data at scale from diverse environments to create annotated datasets for training robotics AI models. The company operates both as a data collection platform where individuals earn money for recording their activities and as a service for businesses whose workers perform physical tasks, offering zero-cost labor in exchange for recording data.

Advanced ManufacturingAI & Machine LearningData & InfrastructureRoboticsSan Francisco, US

Lyem Ningthou(Founder)in

Asimovasimov.io

Asimov builds a computer-aided design platform for genetic engineering and synthetic biology, enabling genetic designers to program living cells through automated circuit design and computational modeling.

AI & Machine LearningBiotechDeep TechBoston, US

Chris Voigt(Co-founder)Doug Densmore(Co-founder)Alec Nielsen(Co-founder & CEO)Raja Srinivas(Co-founder)

Asimovasimov.com

Asimov develops a computer-aided design platform for genetic engineering, enabling designers to program living cells by applying abstraction, standardization, and modeling to biology. The company serves genetic engineers and biotechnology researchers building engineered biological systems.

AI & Machine LearningBiotechDeveloper ToolsBoston, US

Chris Voigt(Co-founder)Doug Densmore(Co-founder)Alec Nielsen(Co-founder & CEO)Raja Srinivas(Co-founder)

BigHat Biosciencesbighatbio.comin๐•

Big Hat Bio develops therapeutics under development across multiple programs. The company is a STEM-focused team working on therapeutic discovery and development.

AI & Machine LearningBiotechDeep TechSan Francisco, US

Calacala.aiin

Cala provides verified, structured data from public sources including financial filings, market data, regulatory information, news, and business registries to AI agents and applications through an API.

AI & Machine LearningData & InfrastructureEnterprise Software

Calacalahealth.comin

Cala Health develops non-invasive prescription therapies for movement disorders, starting with a treatment for hand tremor and essential tremor. The company serves patients with chronic neurological and related conditions using bioelectronic medicine technology.

Deep TechDigital HealthHealthtechMedical DevicesSilicon Valley, US

Deanna Harshbarger(Chief Executive Officer)Kate Rosenbluth, PhD(President & Chief Innovation Officer)

Canvas Technology
Capella Space
Cleanlabcleanlab.ai

Cleanlab develops machine learning tools for data quality and model improvement, serving enterprises and ML practitioners across industries. The company provides automated solutions for identifying and fixing data errors using confident learning technology.

AI & Machine LearningData & InfrastructureDeveloper ToolsEnterprise SoftwareSaaS

Curtis NorthcuttJonas Mueller(Co-founder)inAnish AthalyeAnishathalye(Co-founder)

Code Fourcodefour.usin๐•

Code Four develops AI-powered investigation software for police departments that automates evidence processing and fuses data from body-worn cameras, records management systems, phone dumps, recorded audio, and case files. The platform extracts entities, builds timelines, and generates investigative documents to accelerate criminal inquiries.

AI & Machine LearningGovTechSan Francisco, US

George Cheng(Founder)inDylan Nguyen(Founder)in

CrowdAIcrowdai.comin๐•

CrowdAI provides a no-code platform that enables organizations to build and deploy computer vision applications without requiring deep technical expertise. The platform covers the full lifecycle of vision AI projects, from data labeling and model training to deployment and real-time decision-making across visual data.

AI & Machine LearningEnterprise SoftwareSan Francisco, US

Devaki Raj(Founder/CEO)inNic Borensztein(Founder/CTO)inPablo Garcia(Founder)in

Elegenelegenbio.com

Elegant Bio develops DNA synthesis technology and services, offering ENFINIAโ„ข DNA synthesis at scale for biotech and research applications.

BiotechDeep Tech

Elementum
Endpoint Healthendpointhealth.comin๐•

Endpoint Health develops immunology-focused therapeutics paired with diagnostic tests designed to match individual patients with treatments suited to their biology for critical and chronic illnesses.

BiotechHealthtechSan Francisco, US

Diego Rey(Founder/CSO)inJeff Osborn(Founder)Jason Springs(Founder)inLeonardo Teixeira(Founder)in

Freenome
Geopipegeopipe.aiin

Geopipe creates digital twin technology that generates immersive 3D models of real-world cities and environments for use in games, simulations, training, and architecture. The company serves developers, architects, and enterprises building virtual representations of physical locations.

AI & Machine LearningData & InfrastructureDeep TechGamingNew York City, US

Christopher Mitchell(CEO and Co-Founder)Thomas Dickerson(CSO and Co-Founder)

Inscopixinscopix.com

Inscopix develops advanced microscopy and neural circuit analysis technologies to understand brain function and disease mechanisms for neuroscience research. The company works with academic institutions, biopharmaceutical companies, and government agencies to translate research into therapies for neurological and psychiatric disorders including depression, Parkinson's, Alzheimer's, and PTSD.

AI & Machine LearningBiotechDeep TechMedical DevicesMountain View, US

Kunal Ghosh(Founder & CEO)Abbas El Gamal(Co-founder & Director)Mark Schnitzer(Scientific Cofounder & Board Observer)

MegaBots
Nautilus Biotechnologynautilus.bioin๐•

Nautilus develops proteomics technology to unlock the complexity of the human proteome for biomedical research and diagnostics. The company targets pharmaceutical, biotechnology, academic, clinical, and government sectors with advanced protein quantification and analysis platforms.

BiotechDeep TechMedical Devices

Sujal Patel(Founder & CEO)Parag Mallick(Founder & Chief Scientist)

Nervana Systems
Osaroosaro.comin๐•

OSARO designs AI-powered robotic systems for warehouse automation and fulfillment. The company provides adaptable automation solutions for product picking and handling in logistics and supply chain operations.

AI & Machine LearningLogistics & Supply ChainRobotics

Osmindosmind.orgin๐•

Osmind is a public benefit corporation developing technology and research infrastructure to accelerate evidence-based mental health treatments, including therapies like ketamine, and to improve patient access to care.

AI & Machine LearningBiotechDigital HealthHealthtechMedical DevicesMental HealthSaaSSan Francisco, US

Lucia Huang(Founder)inJimmy Qian(Founder)in

Pepperdatapepperdata.com

Pepperdata provides real-time, automated resource optimization software for data workloads running on Kubernetes and YARN, helping enterprises reduce infrastructure costs by up to 30% without manual intervention. The platform is used by large-scale data operations at Fortune 500 companies and has saved customers over $250 million cumulatively.

Cloud ComputingData & InfrastructureDeveloper ToolsEnterprise SoftwareSaaSSilicon Valley, US

Rigetti Quantum Computing
Synthego
Transcriptictranscriptic.comin๐•

Transcriptic operates a platform that lets researchers conduct experiments using remote robotic laboratory equipment, integrated through a web-based interface that connects instruments and automation for drug discovery and biotech research.

BiotechHealthtechRoboticsSan Francisco, US

Max Hodak(Founder/CEO)in

Vicarious Surgical
Vizviz.aiin๐•

Viz.ai uses artificial intelligence to accelerate care coordination in healthcare settings, reducing delays between patients and life-saving treatments. The company transforms clinical workflows to improve patient outcomes.

AI & Machine LearningDigital HealthHealthtechMedical Devices

Chris Mansi(Co-founder)David Golan(Co-founder)

Frequently asked questions

What stage does AME Cloud Ventures invest at?
AME Cloud Ventures invests at the Seed, Series A, Series B, Series C, Growth, Late Stage stages.
What sectors does AME Cloud Ventures focus on?
AME Cloud Ventures focuses on AI & Machine Learning, Cloud Computing, Data & Infrastructure, Deep Tech, Hardware.
Where is AME Cloud Ventures located?
AME Cloud Ventures is headquartered in Palo Alto, US.

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