Karyopharm Therapeutics
Newton, US · Founded 2008 · 4 known investors
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Karyopharm is a pharmaceutical company developing drugs based on its SINE (Selective Inhibitor of Nuclear Export) technology, with medicines targeting cancers including multiple myeloma and diffuse large B-cell lymphoma. It serves patients and healthcare providers in oncology.
Founders & leadership


Board
Investors · 4
How we know: Avoro Capital Advisors's portfolio page · Not right? Tell us
How we know: Foresite Capital's portfolio page · Not right? Tell us
How we know: HEALTHCARE ROYALTY PARTNERS's portfolio page · Not right? Tell us
How we know: investing.com · funding news · Not right? Tell us
Funding
SEC filings, press & company announcements$165M disclosed across 1 of 2 rounds · 2022–2026
- Undisclosed amountprivate placementMar 2026Source ↗
▶$165MraisedDec 2022 · 33 investors · PharmaceuticalsRule 506(b)
- Peter HonigDirector
- Barry E. GreeneDirector
- Stuart PoultonExecutive Officer
- Michael ManoExecutive Officer
- Reshma RangwalaExecutive Officer
- Richard PaulsonExecutive Officer, Director
- Deepika R. PakianathanDirector
- Chen SchorDirector
- Stephen MitchenerExecutive Officer
- Michael MasonExecutive Officer
- Mansoor Raza MirzaDirector
- Garen G. BohlinDirector
- Christy J. OligerDirector
- Sohanya ChengExecutive Officer
- Offering amount
- $165M
- Amount sold
- $165M
- Sales commissions
- $9.9M
- Placement agents
- Robert W. Baird & Co. Incorporated, Piper Sandler & Co., Jefferies LLC, Barclays Capital, Inc., H.C. Wainwright & Co. LLC
- First sale
- Dec 2022
- Incorporated
- Corporation, Delaware
- Federal exemptions
- 06b
Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.
Related companies · 3
Companies working in the same space as Karyopharm Therapeutics.
Non-dilutive funding · 2 SBIR/STTR awards
Federal grants — no equity taken| Agency | Phase | Year | Amount |
|---|---|---|---|
| National Institutes of Health (NIH)National Institutes of Health | Phase II | 2018 | $2M |
| National Institutes of Health (NIH)National Institutes of Health | Phase I | 2016 | $225K |
Source: SBIR.gov award data (U.S. Small Business Administration). SBIR/STTR awards are competitive federal R&D grants and contracts — non-dilutive capital alongside any venture rounds above.
In the news
Frequently asked questions
- What does Karyopharm Therapeutics do?
- Karyopharm is a pharmaceutical company developing drugs based on its SINE (Selective Inhibitor of Nuclear Export) technology, with medicines targeting cancers including multiple myeloma and diffuse large B-cell lymphoma. It serves patients and healthcare providers in oncology.
- Who are Karyopharm Therapeutics's investors?
- Karyopharm Therapeutics's investors include Avoro Capital Advisors, Foresite Capital, HEALTHCARE ROYALTY PARTNERS, RA Capital.
- How much funding has Karyopharm Therapeutics raised?
- Karyopharm Therapeutics has disclosed $165M raised across 1 of its 2 known rounds.
- Where is Karyopharm Therapeutics headquartered?
- Karyopharm Therapeutics is headquartered in Newton, US.




