/Companies

Karyopharm Therapeutics

Newton, US · Founded 2008 · 4 known investors

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Karyopharm is a pharmaceutical company developing drugs based on its SINE (Selective Inhibitor of Nuclear Export) technology, with medicines targeting cancers including multiple myeloma and diffuse large B-cell lymphoma. It serves patients and healthcare providers in oncology.

Founders & leadership

SPStuart Poulton
Stuart PoultonExecutiveStuart Poulton is Executive Vice President and Chief Development Officer at Karyopharm Therapeutics, overseeing global clinical development operations. He previously led strategic portfolio management at AbbVie and brings experience spanning drug development across oncology, bone health, cardiovascular, diabetes, anti-infectives, immunology, and neuroscience throughout his pharmaceutical industry career.
MM
Michael ManoExecutiveExecutive Officer at Karyopharm
RRReshma Rangwala
Reshma RangwalaExecutiveRangwala holds an MD with specialization in medical oncology and a doctorate in cell biology/neurosciences, with extensive clinical development experience in oncology and immunology spanning multiple cancer indications including lung, hepatocellular, ovarian, and melanoma, as well as expertise in immunotherapy, companion diagnostics, and regulatory interactions with health agencies.
RPRichard Paulson
Richard PaulsonCEORichard Paulson has spent over 25 years in the life sciences industry in various roles across global organizations. He serves as Executive Officer and Director at Karyopharm, a pharmaceutical company developing SINE technology-based medicines for oncology indications including multiple myeloma and diffuse large B-cell lymphoma.
SMStephen Mitchener
Stephen MitchenerExecutiveExecutive Officer at Karyopharm
MM
Michael MasonExecutiveExecutive Officer at Karyopharm
PH
Peter HonigNamed on SEC filing
CS
Chen SchorNamed on SEC filing

Board

DR
Deepika R. PakianathanBoard director
BE
Barry E. GreeneBoard director
MR
Mansoor Raza MirzaBoard director
GG
Garen G. BohlinBoard director

Investors · 4

Funding

SEC filings, press & company announcements

$165M disclosed across 1 of 2 rounds · 2022–2026

▶$165MraisedDec 2022 · 33 investors · Pharmaceuticals
Rule 506(b)
Officers, directors & promoters on the filing
  • Peter HonigDirector
  • Barry E. GreeneDirector
  • Stuart PoultonExecutive Officer
  • Michael ManoExecutive Officer
  • Reshma RangwalaExecutive Officer
  • Richard PaulsonExecutive Officer, Director
  • Deepika R. PakianathanDirector
  • Chen SchorDirector
  • Stephen MitchenerExecutive Officer
  • Michael MasonExecutive Officer
  • Mansoor Raza MirzaDirector
  • Garen G. BohlinDirector
  • Christy J. OligerDirector
  • Sohanya ChengExecutive Officer
Offering amount
$165M
Amount sold
$165M
Sales commissions
$9.9M
Placement agents
Robert W. Baird & Co. Incorporated, Piper Sandler & Co., Jefferies LLC, Barclays Capital, Inc., H.C. Wainwright & Co. LLC
First sale
Dec 2022
Incorporated
Corporation, Delaware
Federal exemptions
06b
Full filing on SEC EDGAR ↗

Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.

Related companies · 3

Companies working in the same space as Karyopharm Therapeutics.

Non-dilutive funding · 2 SBIR/STTR awards

Federal grants — no equity taken
AgencyPhaseYearAmount
National Institutes of Health (NIH)National Institutes of HealthPhase II2018$2M
National Institutes of Health (NIH)National Institutes of HealthPhase I2016$225K

Source: SBIR.gov award data (U.S. Small Business Administration). SBIR/STTR awards are competitive federal R&D grants and contracts — non-dilutive capital alongside any venture rounds above.

In the news

Frequently asked questions

What does Karyopharm Therapeutics do?
Karyopharm is a pharmaceutical company developing drugs based on its SINE (Selective Inhibitor of Nuclear Export) technology, with medicines targeting cancers including multiple myeloma and diffuse large B-cell lymphoma. It serves patients and healthcare providers in oncology.
Who are Karyopharm Therapeutics's investors?
Karyopharm Therapeutics's investors include Avoro Capital Advisors, Foresite Capital, HEALTHCARE ROYALTY PARTNERS, RA Capital.
How much funding has Karyopharm Therapeutics raised?
Karyopharm Therapeutics has disclosed $165M raised across 1 of its 2 known rounds.
Where is Karyopharm Therapeutics headquartered?
Karyopharm Therapeutics is headquartered in Newton, US.