/Investor DB

RA Capital — 2025 Investments

24 investments dated 2025 · listed companies and verified rows first · show all

Adagio Medical HoldingsNASDAQ: ADGMOct 2025

Adagio Medical Holdings develops and commercializes catheter-based ablation devices using proprietary Ultra-Low Temperature Ablation technology to treat ventricular tachycardia, a life-threatening abnormal heart rhythm, primarily in patients with structural heart disease.

HealthtechLaguna Hills, US

Todd Usen(Executive Officer, Director)inDeborah Kaster(Executive Officer)in

BoardKeyvan Mirsaeedi-Farahani(Director)Orly Mishan(Director)James L. Cox(Director)Timothy P. Moran(Director)

Damora TherapeuticsNASDAQ: DMRANov 2025 · $284.9M

Damora Therapeutics is a preclinical-stage biotechnology company that discovers and develops therapeutic candidates, including DMR-001, DMR-002, and DMR-003, with the goal of advancing treatments through investigational drug applications and clinical trials.

BiotechCopenhagen, US

Garrett Winslow(Executive Officer)inLori Firmani(Executive Officer)inHans T. Schambye(Executive Officer, Director)Jennifer Jarrett(President, Chief Executive Officer and Director)inBecker Hewes(Chief Medical Officer)Sherwin Sattarzadeh(Chief Operating Officer)

Co-investorsAccess BiotechnologyViking GlobalAndreessen HorowitzBAM ElevateBay City CapitalCommodore Capital+8 more

Rani Therapeutics HoldingsNASDAQ: RANIOct 2025

Rani Therapeutics is a clinical-stage biopharmaceutical company developing oral delivery technologies for biologics and drugs, primarily through its proprietary RaniPill capsule platform, which comes in two configurations (RaniPill GO for up to 3 mg microtablet doses and RaniPill HC for up to 200µL liquid doses).

BiotechSan Jose, US

Talat Imran(Executive Officer, Director)inSvai Sanford(Executive Officer)inMir Hashim(Executive Officer)in

BoardAbraham Bassan(Director)Vasudev Bailey, M.D.(Director)Mir Imran(Director)

Co-investorsInCube Ventures

Bambusa Therapeuticsbambusatx.cominFeb 2025✓ verified

Bambusa Therapeutics develops bispecific antibodies for immunological and inflammatory (I&I) disorders, using antibody engineering to target multiple I&I indications.

BiotechHealthtechMedical DevicesAustin, US

Shanshan Xu(Founder & Chief Executive Officer)inHelmut Jeggle(Co-Founder)inThang Ho(Chief Development Officer)inCrystal MacKay(Chief Operating Officer)in

Board seatDerek DiRocco· per SEC Form D

Co-investorsINCE CapitalSalviaBiotechnology Value FundJanus Henderson InvestorsREDMILE

HYKU Bioscienceshykubiosciences.cominDec 2025✓ verified

Hyku Biosciences develops small molecule therapeutics with novel mechanisms of action designed to covalently bind non-cysteine amino acids and inactivate disease-driving proteins.

BiotechDeep TechMedical DevicesBurlington, US

KLEEM CHAUDHARY(Executive Officer, Director, Promoter)inKu-Lung (Ken) Hsu, PhD(Scientific Founder)Kleem Chaudhary, PhD(President & CEO)

BoardJOHN GUSTOFSON(Director)LAURA BRASS(Director)inLAURA TADVALKAR(Director)in

Co-investorsDroia VenturesEisai Innovation, Inc.Novartis Venture Fund

Indapta Therapeuticsindapta.comMay 2025 · $50M✓ verified

Indapta Therapeutics develops an off-the-shelf, allogeneic FcRγ-deficient natural killer (g-NK) cell therapy derived from healthy donors to treat cancer and autoimmune diseases.

BiotechHealthtechHouston, US

Guy DiPierro(Chief Operating Officer & Co-Founder)inSungjin Kim(Scientific Founder)John Sunwoo(Scientific Founder)Mark W. Frohlich(Chief Executive Officer)Stefanie Mandl-Cashman(Acting Chief Scientific Officer)

BoardLori Hu(Director)in

Co-investorsLeaps by BayerVertex Ventures HC

Rivus Pharmaceuticals, Inc.rivuspharma.comin𝕏Jan 2025SEC filingmedium confidence

Rivus Pharmaceuticals develops mitochondrial-targeted therapies to treat cardiometabolic diseases.

BiotechDigital HealthHealthtechMedical DevicesCharlottesville, US

Francisco Portell(Co-founder & Vice President, Pharmaceutical Development)Allen Cunningham(Co-founder & Chief Operating Officer)inNancy Hargreaves(Executive Officer)Jayson Dallas(Executive Officer, Director)inShaharyar Khan(Co-founder & Chief Scientific Officer)in

BoardFrancesco De Rubertis(Director)in

Board seatDerek DiRocco· per SEC Form D · $57M raise · filed Jan 2025

Co-investorsMedicxiBain Capital Life SciencesLongitude Capital

Superluminal Medicinessuperluminalrx.cominAug 2025

Uses ML and big data to accelerate drug development.

AI & Machine LearningBiotechDeep TechHealthtechMedical DevicesWaltham, US

Ajay Yekkirala, PhD(Founder)inRyan Bloom(Founder)inCATHERINE RIESEN(Executive Officer)CONY D'CRUZ(Executive Officer, Director, Promoter)inCRAIG RANDALL(Executive Officer)Ajay Yekkirala(Founder)

Board seatNandita ShangariAndrew Levin· per SEC Form D

Co-investorsGaingelsInsight PartnersNVenturesNVIDIA

Ambagon Therapeuticsambagontx.comin𝕏Jan 2025

Ambagon develops small molecule stabilizers of 14-3-3 protein complexes to modulate disease-related protein interactions, targeting therapeutic areas including cancer, metabolic disorders, neurodegenerative and infectious diseases.

BiotechDeep TechMedical DevicesEindhoven, US

Christian Ottmann(Executive Officer)inJosh Seidenfeld(Executive Officer)Michelle Arkin(Director)Nancy Pryer(Executive Officer)Margarita Chavez(Director)Bryan Miller(Executive Officer)

Co-investorsDroia VenturesInkefMission BiocapitalMRL Ventures FundNextech Invest

Ambros Therapeuticsambrostherapeutics.comDec 2025acquired by Werewolf Therapeutics · Aug 2026 · $500M

Ambros Therapeutics is a therapeutics company.

BiotechHealthtechSan Diego, US

Joseph (Jay) Hagan(President and Chief Executive Officer)

Co-investorsLifeSci Venture PartnersBAM ElevateJanus Henderson InvestorsPatient Square Capital

Arterialarterial.usinJul 2025 · $14M

Arterial automates roadway asset inventory, inspection, and condition assessment by passively collecting data from vehicles already driving a network, detecting and ranking infrastructure problems like potholes for public agencies.

AI & Machine LearningConstruction TechData & InfrastructureGovTechMobility & TransportationBoulder, US

Wade Turner(Founder)in

Co-investorsTechstarsAN Venture Partners

Artios Pharmaartios.comin𝕏Nov 2025 · $115M

Artios develops DNA damage response (DDR)-based medicines targeting patients with high unmet need cancers.

BiotechHealthtechMedical Devices

Co-investorsAndera PartnersDementia Discovery FundM VenturesNovartis Venture FundPfizer Venture InvestmentsSofinnova Partners+6 more

Azalea Therapeuticsazaleatx.cominNov 2025

Azalea Therapeutics develops precision genome editing therapies that engineer T cells directly inside the patient's body to create cancer immunotherapies, using proprietary delivery vehicles to target and modify specific genetic loci without ex vivo cell manipulation.

AI & Machine LearningBiotechMedical DevicesSan Francisco, US

Jennifer Doudna(Co-founder, Nobel Laureate in Chemistry and Li Ka Shing Chancellor's Chair in Biomedical and Health Sciences, UC Berkeley)Rodolphe Barrangou(Co-founder, Associate Professor of Medicine, UCSF)Krishnendu Roy(Co-founder, Professor of Bioengineering, Stanford University)Connor Tsuchida(Scientific Cofounder)in

Co-investorsThird Rock VenturesSozo VenturesYosemite

Commons Cliniccommonsclinic.comJan 2025

Commons Clinic is an orthopedic care provider offering treatment for spine, joint, and sports medicine conditions, along with preventive health services such as full-body MRI and biomarker labs.

Digital HealthHealthtechWellness & FitnessAustin, US

Brad Hively(Director)inNick Aubin(Founder)inPaulo Marques Da Costa(Executive Officer, Director)Prithviraj Singha Roy(Director)in

BoardJohn Loser(Director)inDavid Berry(Director)in

Co-investorsCourtside VenturesFloating PointGaingelsNorth South VenturesSteelSky VenturesTime BioVentures+2 more

Curevo Vaccinecurevovaccine.cominMar 2025 · $110M

Curevo Vaccine is a biotech company developing next-generation non-mRNA vaccines, with a focus on infectious diseases.

BiotechHealthtech

George Simeon(CEO)inGregory S. Curhan(CFO)Guy De La Rosa(CMO)in

Co-investorsAdjuvant CapitalOrbiMedSanofi VenturesHBM Healthcare InvestmentsJanus Henderson InvestorsMedicxi

Electra Therapeuticselectra-therapeutics.cominOct 2025

Electra Therapeutics develops antibody therapeutics targeting Signal Regulatory Protein (SIRP) for immunological diseases and cancer treatment.

BiotechHealthtechMedical DevicesSouth San Francisco, US

Adam Rosenthal(Co-founder and former CEO; Director)inQuehuong (Kathy) Dong, Pharm.D.(Executive Officer, Director)Kathy Dong(President, Chief Executive Officer and Director)in

BoardBeth Seidenberg, M.D.(Director)Thomas Geninatti, Ph.D.(Director)Carl Gordon, Ph.D.(Director)

Co-investorsHBM Healthcare InvestmentsHBM PartnersOrbiMedWestlake Village BioPartnersKleiner PerkinsNVIDIA

EvodiaBioevodiabio.cominDec 2025

Evodia is a Danish aroma company that uses precision fermentation with proprietary yeast strains to produce monoterpenes, the natural molecules behind flavor and aroma, as a sustainable alternative to plant-derived ingredients.

BiotechCleantechClimate TechDeep TechFoodTechCopenhagen, DK

Co-investorsNordic Foodtech VCPINCThe March Group

Imbriaimbria.cominNov 2025 · $57.5M

Imbria Pharmaceuticals develops novel cardiovascular disease treatments that target cardiac energy metabolism, with a lead drug candidate, ninerafaxstat, in clinical trials for non-obstructive hypertrophic cardiomyopathy.

BiotechDigital Health

Alvin Shih(CEO)inAlbert M. Kim(Chief Medical Officer)in

Co-investorsAN Venture PartnersCatalio Capital Management, LPSanofi VenturesSV Health InvestorsCatalio Capital Management

Reframe Systemsreframe.systemsin𝕏Aug 2025 · $20M

Reframe helps developers and builders deliver construction projects—from small multi-unit builds to community-scale developments—with more predictable timelines and outcomes.

Climate TechConstruction TechPropTechRobotics

Aaron Small(Founder)in

Co-investorsCubit CapitalEnergy Impact PartnersFoundamentalGlobal BrainService Provider CapitalVoLo Earth Ventures+2 more

Star Therapeuticsstar-therapeutics.comSep 2025

Star Therapeutics develops treatments aimed at addressing real-world patient needs.

BiotechSouth San Francisco, US

Adam Rosenthal(Founder & CEO)inNancy Stagliano(Director)inMichelle Carpenter(Executive Officer)Sandip Panicker(Executive Officer)Scott Robertson(Executive Officer)inGary Patou(Executive Officer)in

Co-investorsFrazier Life SciencesOrbiMedSanofi VenturesSofinnova VenturesViking GlobalAgent Capital+11 more

Other

Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.

NanoMosaicVaxess Technologies, Inc.Imbria PharmaceuticalsVitriVax

Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.