How many investments has First In Ventures made?

First In Ventures has 26 tracked investments.

What stage does First In Ventures invest at?

First In Ventures invests at the Pre-Seed, Seed stages.

What is First In Ventures's typical check size?

First In Ventures typically writes checks of $50K – $200K.

Where is First In Ventures located?

First In Ventures is headquartered in Middletown, US.

Does First In Ventures lead rounds?

Yes, First In Ventures leads investment rounds.

Who does First In Ventures co-invest with?

First In Ventures most often shares deals with Better Ventures Central Llc, Illumina Ventures, Entrepreneur First, among 24 tracked co-investors.

First In Ventures

Venture capital

Middletown · Pre-Seed–Seed · 5 people tracked

★ Follow + Add to CRM ⤳ Find an introduction

✨ Fox Verdict

Investment thesis

A Middletown, Delaware–based firm specializing in early-stage biotech and life sciences.

Invests inAI & Machine Learning Biotech Data & Infrastructure Healthtech Medical Devices Middletown United States

Source: firm website, verified Aug 7, 2026.

Stage

Pre-Seed–Seed

Check

$50K – $200K

Middletown, Delaware, US

Leads rounds

Leads

Instruments

Equity

Founded

2020

Tracked investments

Team · 5 people

from the firm's website & public directories

Kyle Rusconi· Founder· Concord, Massachusetts, United Statesin

Founder of First In Ventures who began his career on early high-frequency trading desks and led trading teams across Asia and North America over seventeen years in banking. He is now CEO of Cognitive Genetics, which went through the Illumina Accelerator, an experience that inspired the creation of First In Ventures.

Scott Roth· Managing Member· Greenwich, CTin

An investor who founded two large institutional hedge funds (Severn River and Sagamore Hill) managing billions in assets from 1999 to 2014, and now runs his family office investing in public and private securities. He previously worked as a nuclear engineer for the Navy, a proprietary trader at Goldman Sachs, and attended Harvard Business School.

Andrew Sieghart· Investment Committee

A former Lehman Brothers executive in global real estate and principal transactions, later holding senior roles at Nomura Securities and G2 Investment Group focused on structured asset-based equity and debt investments. He is currently Managing Partner at Framework Capital Partners, a family office.

Richard D. Levinson· Investment Committee

A founding partner of Canaras Capital Management, a New York SEC RIA focused on corporate credit, and a principal of Sage Group advising on structured finance. He previously spent 18 years at Citibank in senior treasury and structured finance roles and holds degrees from Union College and the Wharton School.

Ven Medabalmi· Investment Committee

A serial entrepreneur and operator who invests through his family office with a portfolio of over 50 startup investments. He holds bioengineering and law degrees from the University of Pennsylvania and Columbia University, with experience spanning startups, IP and venture law, and operational management.

What they invest in

from 20 of 27 portfolio companies

Biotech ×19Deep Tech ×8Healthtech ×8AI & Machine Learning ×5Digital Health ×5Medical Devices ×4AgTech ×2Climate Tech ×2

HQs:United States×5United Kingdom×1India×1

Investments · 27 tracked

founders shown can be your intro path

By year:2023 · 1 2021 · 1 2020 · 13 dated

Humacytehumacyte.com in 𝕏NASDAQ: HUMA

Humacyte is a regenerative medicine company that develops a bioengineered, human-derived Acellular Tissue Engineered Vessel (ATEV) along with a scalable cell sourcing and manufacturing platform.

BiotechHealthtechMedical DevicesMorrisville, US

Laura E. Niklason(Director)Ted Lithgow(Executive Officer)Paul Boyer(Executive Officer)Carrie S. Cox(Executive Officer, Director)

BoardRobert Anderson(Director)Robert Langer(Director)

Co-investorsFresenius Medical Care Ventures Oberland Capital

Pluton Biosciencesplutonbio.com in✓ verified

Pluton Biosciences develops novel microbes and scales them to industrial volumes at commodity pricing for agriculture and climate applications.

AgTechBiotechClimate TechDeep TechSt. Louis, US

Barry Goldman(Co-founder)Elizabeth Gallegos(Chief Executive Officer)Jerry Steiner(Executive Chair)Charlie Walch(Executive Officer, Director)Glendon Schuster(Director)

Co-investorsIllumina Ventures Radicle Growth Better Ventures Fall Line Capital Grantham Foundation RA Capital +4 more

Gliknikgliknik.comJun 2023

Baltimore-based immunology company focused on treatments for cancer and autoimmune disorders; raised an $11.5 million Series C led by First In Ventures.

BiotechBaltimore, US

David S. Block(Executive Officer, Director)Elizabeth C. Block(Executive Officer)Raymond Shinazi(Director)Joseph Klein(Director)Elizabeth Block(Executive Officer)Mark Lerner(Director)

Board seatKyle Rusconi· per SEC Form D

Co-investorsBrace Pharma

4BaseCare4basecare.com in

4baseCare develops AI-powered precision oncology tools that combine genomic data, clinical history, and real-world evidence to support cancer treatment decisions, molecular tumor board collaboration, biomarker discovery, and clinical trial design.

AI & Machine LearningBiotechDigital Health

Hitesh Goswami(CEO)Kshitij Rishi(COO)Puneet Pantane(CDO)

Co-investorsMerak Ventures Mount Judi Ventures Season Two Ventures Yali Capital

Aarogyaaarogya.ai

Biotaxbiotax.co in

EcoBiotaX develops a microbial ecology platform that uses AI (its ecoSat computational platform) and biological methods to discover and construct natural bacterial communities for specific biological functions.

AgTechAI & Machine LearningBiotech

Naama Geva-Zatorsky(Co-Founder)Shay Hilel(Co-Founder & CEO)Dean Light(Co-Founder & CTO)

Co-investorsZORA

Broken String Biosciencesbrokenstringbio.com in

Broken String Bio provides off-target analysis for gene editing using its INDUCE-seq technology, which detects genome-wide DNA double-strand break events through a wet-lab assay paired with a bioinformatics platform.

AI & Machine LearningBiotechData & InfrastructureDeep TechMedical Devices

Co-investorsHeran Partners Illumina Ventures Korys Mérieux Equity Partners

Celldomcelldom.com in

Celldom builds a live single-cell biology platform that uses microwell arrays in standard culture plate format, automated imaging, incubation, and real-time analysis to measure morphology, phenotypes, secreted proteins, gene expression, and cell-cell interactions across more than 100,000 cells per plate.

BiotechDeep TechHardware

Co-investorsTSVC

Cognitivegeneticscognitivegenetics.com

Doloromicsdoloromics.com

Epicombiepicombi.ai

Felix Biotechnologyfelixbt.com in 𝕏Defunct

Felix Biotechnology develops a digital platform for designing viruses intended to combat antimicrobial resistance.

BiotechHealthtechSan Francisco, US

Robert McBride(Founder)inVivek Mutalik(Founder)inPaul Turner(Founder)in

Co-investorsPoint72 Ventures Y Combinator

Flightpathflightpath.bio in

Flightpath Biosciences develops Targeted Bacterial Deletion, a platform that selectively removes harmful gram-negative bacteria while sparing the surrounding microbiome to interrupt infection-driven disease.

BiotechDeep TechHealthtech

Co-investorsID Ventures Michigan Rise

Futuragenomicsfuturagenomics.com

Futura Genomics offers direct-to-consumer genetic testing, starting with a basic cheek-swab DNA test and over 24 additional unlockable tests delivered through an online dashboard.

BiotechConsumerDigital Health

Lassogenlassogen.com in 𝕏Sep 2020

Lassogen is a biotechnology company focused on developing new treatments for disease.

BiotechDeep TechSan Diego, US

Mark J Burk(Executive Officer)

Co-investorsBetter Ventures Central Llc Playground Global

Lightspeedbiolightspeedbio.com in 𝕏

Alpenglow Biosciences develops the Aurora 3D spatial biology platform, combining open-top light-sheet microscopy, volumetric data processing, and AI analysis to turn intact tissue into quantitative 3D data.

AI & Machine LearningBiotechMedical Devices

Mablemeetmable.com

Mable provides software for food and beverage distributors in the United States, supporting online ordering and catalog management.

Co-investorsG20 Ventures NFX Underscore VC Arkitekt Ventures Venrock Y Combinator

Medic Life Sciencesmedic-life-sciences.com

Medic Life Sciences applies CRISPR functional genomics in 3D patient tumor-like cancer models to identify biomarkers, synthetic lethality, and resistance mutations for oncology drug development.

BiotechDeep TechHealthtech

Mitra Biomitrabio.tech in

Mitra develops a non-invasive skin diagnostics platform that combines clinical trials, skin sampling, next-generation sequencing, and data science to guide the design of age-rejuvenating skincare compounds.

BiotechDeep TechDigital HealthHealthtechLongevityMedical DevicesLondon, GB

Shakiba Kaveh(CEO)inCristiana Banila(CTO)in

Co-investorsEntrepreneur First Merian Ventures

Multiplaihealthmultiplaihealth.com in 𝕏

MultiplAI Health is developing an RNA-sequencing and AI-based whole blood screening test to detect complex diseases, with a focus on cardiovascular disorders and cancer.

AI & Machine LearningBiotechDigital Health

Neurolytic Healthcareneurolytic-healthcare.comDec 2021

HealthtechLondon

Roman Rothaermel(Executive Officer, Director, Promoter)Tom Kent(Executive Officer, Director, Promoter)Inna Thalmann(Executive Officer, Director, Promoter)Parul Singh(Director)

Parallelhealthparallelhealth.io

Parallel Health is a licensed teledermatology practice offering the MD-03 Protocol, a three-step system combining whole genome microbiome sequencing, 1:1 clinical consultations, and custom phage-based serums.

BiotechDigital HealthDirect to Consumer

Co-investorsAxial VC Hyphen Capital

Prenome

Startup developing a way to help pregnant women predict and manage gestational diabetes; participated in TechCrunch Disrupt Startup Battlefield.

Stempharmstempharm.com in 𝕏

Stem Pharm develops human neural organoids featuring microglia and chemically-defined synthetic hydrogel substrates for in vitro modeling of neuroinflammatory diseases.

BiotechDeep TechHealthtech

Tailortailor.bio

Tailor Bio develops targeted cancer therapies for tumors characterized by chromosomal instability, working in the field of precision oncology.

BiotechHealthtech

Wellsimbiotechwellsimbiotech.com

Yali Bioyalibio.com in

Yali Bio develops climate-friendly fats and lipids designed for alternative dairy products such as butter, ice cream, milk, and cheese, using fewer inputs than conventional sources.

BiotechClimate TechFoodTech

Co-investorsFTW Ventures S2G Investments

Exits · 1

IPOs and acquisitions across the tracked portfolio

HumacyteNASDAQ: HUMA

Frequently asked questions

How many investments has First In Ventures made?: First In Ventures has 26 tracked investments.
What stage does First In Ventures invest at?: First In Ventures invests at the Pre-Seed, Seed stages.
What is First In Ventures's typical check size?: First In Ventures typically writes checks of $50K – $200K.
What sectors does First In Ventures focus on?: First In Ventures focuses on AI & Machine Learning, Biotech, Data & Infrastructure, Healthtech, Medical Devices.
Where is First In Ventures located?: First In Ventures is headquartered in Middletown, US.
Does First In Ventures lead rounds?: Yes, First In Ventures leads investment rounds.
Who does First In Ventures co-invest with?: First In Ventures most often shares deals with Better Ventures Central Llc, Illumina Ventures, Entrepreneur First, among 24 tracked co-investors.

Images

Similar investors

GoAhead Ventures

GoAhead Ventures is a venture capital firm that operates like a startup, using a streamlined one-way video pitch process where all three managing partners review every submission and deliver fast investment decisions.

$500K – $1M

Khosla Ventures

Khosla Ventures is a venture capital firm that invests in early-stage companies focused on technology, mobile, and clean energy sectors, including biotechnology applications. The firm provides capital and strategic support to entrepreneurs developing breakthrough technologies across multiple markets.

IDG Capital is a multi-strategy investment platform founded in 1993 that supports entrepreneurs across the full business lifecycle, bridging East and West with a global presence and over 300 professionals.

$3M – $200M

Mitsui Global Investment

Mitsui Global Investment is an investment firm that provides capital and hands-on support to entrepreneurs, helping innovative teams scale their businesses onto the global stage.

$500K – $10M