First In Ventures
Venture capitalActively deployingMiddletown · Pre-Seed–Seed · 7 people tracked
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873 people in our graph share verified history with the First In Ventures team — schools, employers, funds. One of them is your warm intro.
Investment thesis
A Middletown, Delaware–based firm specializing in early-stage biotech and life sciences.
Source: firm website, verified Aug 7, 2026.
Team · 7 people
from the firm's website & public directoriesWhat they invest in
from 24 of 30 portfolio companiesBiotech ×20Healthtech ×12AI & Machine Learning ×10Medical Devices ×8Digital Health ×7Deep Tech ×6Enterprise Software ×3AgTech ×2
HQs:United States×9United Kingdom×2India×1South Africa×1
Who they back
founder profiles across 10 portfolio companiesFounding team size:solo founder×42 founders×43 founders×2
What their founders studiedfrom 12 founders with field-of-study data
Life Sciences ×5Engineering ×4Computer Science ×2
Where their founders worked beforefrom 11 founders with career history
Technion ×2Yale University ×2
Investments · 30 tracked
founders shown can be your intro pathBy year:2025 · 12023 · 22022 · 22021 · 12020 · 17 dated
Humacyte is a regenerative medicine company that develops a bioengineered, human-derived Acellular Tissue Engineered Vessel (ATEV) along with a scalable cell sourcing and manufacturing platform.
BiotechHealthtechMedical DevicesMorrisville, US
Laura E. Niklason(Director)inLaura Niklason, MD, PhD(Founder)inTed Lithgow(Executive Officer)inPaul Boyer(Executive Officer)inCarrie S. Cox(Executive Officer, Director)Dale A. Sander(Chief Financial Officer, Chief Corporate Development Officer and Treasurer)in
Co-investorsFresenius Medical Care VenturesOberland Capital
Pluton is developing a sun-powered, soil-surface biological nutrient system that uses photosynthetic microbial consortia to fix atmospheric nitrogen, improve phosphorus availability, and add carbon to soil for crop growers.
AgTechBiotechClimate TechSt. Louis, US
Barry Goldman(Co-founder)inElizabeth Gallegos(Chief Executive Officer)inJerry Steiner(Executive Chair)inCharlie Walch(Executive Officer, Director)inGlendon Schuster(Director)
Co-investorsIllumina VenturesRadicle GrowthFall Line CapitalGrantham FoundationRA CapitalThe Yield Lab+3 more
Baltimore-based immunology company focused on treatments for cancer and autoimmune disorders; raised an $11.5 million Series C led by First In Ventures.
BiotechBaltimore, US
David S. Block(Executive Officer, Director)Elizabeth C. Block(Executive Officer)Raymond Shinazi(Director)Joseph Klein(Director)Mark Lerner(Director)
BoardCharles Polsky(Director)
Board seatKyle Rusconi· per SEC Form D
Co-investorsBrace Pharma
4baseCare delivers personalized cancer care using genomic data, AI analytics, and clinico-genomic datasets tailored to different populations.
AI & Machine LearningBiotechDigital HealthHealthtechMedical Devices
Hitesh Goswami(Founder/CEO)inKshitij Rishi(COO)inPuneet Pantane(CDO)inDr. Giridharan Periyasamy
Co-investorsgrowX VenturesMerak VenturesMount Judi VenturesSeason Two VenturesYali Capital
N-able delivers unified cybersecurity and data protection solutions including endpoint management (N-central), AI-powered threat detection and response (Adlumin), and disaster recovery services (Cove).
AI & Machine LearningCloud ComputingCybersecurityEnterprise SoftwareAlexandria, US
Robert S. Jonhston(Executive Officer, Director)
Co-investorsBankTech VenturesJHH vcSyn Ventures Seed Management LlcFirst InLeawood Venture Capital Llc
Antithesis provides deterministic simulation testing software that automatically finds and reproduces bugs in mission-critical software systems.
AI & Machine LearningDeveloper ToolsEnterprise SoftwareSaaS
Will Wilson(CEO & Co-Founder)inDave Scherer(Co-Founder)Nick Lavezzo(Founder)in
Co-investorsAmplify PartnersTamarack GlobalBoulder VenturesFrontline VenturesNat TurnerOlima Ventures+4 more
EcoBiotaX develops a microbial ecology platform that uses AI (its ecoSat computational platform) and biological methods to discover and construct natural bacterial communities for specific biological functions.
AgTechAI & Machine LearningBiotech
Naama Geva-Zatorsky(Co-Founder)inShay Hilel(Co-Founder & CEO)inDean Light(Co-Founder & CTO)in
Co-investorsZORA
Broken String Biosciences develops tools for genome-wide on- and off-target analysis in gene editing, enabling in-house detection and characterization of gene editing-induced DNA breaks.
AI & Machine LearningBiotechDeep Tech
Co-investorsHeran PartnersIllumina VenturesKorysMérieux Equity Partners
Felix Biotechnology develops a digital platform for designing viruses intended to combat antimicrobial resistance.
BiotechHealthtechSan Francisco, US
Robert McBride(Founder)inVivek Mutalik(Founder)inPaul Turner(Founder)in
Co-investorsPoint72 VenturesY CombinatorAgrolimen VenturesPioneer
Flightpath Biosciences develops microbiome-sparing, pathogen-specific drug candidates to treat infection-associated diseases by selectively targeting harmful bacteria while preserving healthy microbial communities.
BiotechDeep TechDigital HealthHealthtechMedical DevicesBirmingham, US
Matt Tindall(Founder)inMark P. de Souza(Executive Officer, Director)
BoardCurtis Scribner(Director)Cristina Larkin(Director)
Co-investorsID VenturesMichigan RiseWMU Biosciences Research & Commercialization CenterActive Capital
Flowscope deploys AI agents that learn how businesses operate and automate work on top of existing systems within days.
AI & Machine LearningDeveloper ToolsEnterprise SoftwareSan Francisco, US
Samuel Mirpuri(Founder)inJavier Leguina(Founder)in
Co-investorsY Combinator
Futura Genomics provides accredited genetic testing services that deliver personalized health and ancestry insights tailored to diverse populations, with particular focus on African heritage.
BiotechConsumerDigital HealthHealthtech
Lassogen engineers lasso peptides — structurally unique 3D scaffolds — into therapeutics it calls Lassotides, designed to combine the strengths of antibodies and small molecules.
AI & Machine LearningBiotechSan Diego, US
Mark J Burk(Executive Officer)in
Co-investorsBetter Ventures Central LlcPlayground Global
Alpenglow Biosciences develops the Aurora 3D spatial biology platform, combining open-top light-sheet microscopy, volumetric data processing, and AI analysis to turn intact tissue into quantitative 3D data.
AI & Machine LearningBiotechMedical Devices
Mable is a genomics-based telehealth platform that provides personalized migraine care by analyzing patients' genetic and biomarker data to inform individualized treatment plans.
AI & Machine LearningBiotechDigital HealthHealthtechMedical DevicesLondon, GB
Roman Rothaermel(Founder)inInna Thalmann(Founder)inChris EijsboutsinKumeren Govnder
Co-investorsInitialized CapitalUnderscore VCVenrockY CombinatorArkitekt VenturesHarvard Management Company
Medic Life Sciences applies CRISPR functional genomics in 3D patient tumor-like cancer models to identify biomarkers, synthetic lethality, and resistance mutations for oncology drug development.
BiotechDeep TechHealthtech
Kyuho Han(Chief Executive Officer/Co-Founder)Hong-Pyo Lee(Chief Technology Officer/Co-Founder)
Co-investorsBig Basin CapitalSazze
Mitra develops a non-invasive skin diagnostics platform that combines clinical trials, skin sampling, next-generation sequencing, and data science to guide the design of age-rejuvenating skincare compounds.
BiotechDeep TechDigital HealthHealthtechLongevityMedical DevicesLondon, GB
Shakiba Kaveh(CEO)inCristiana Banila(CTO)in
Co-investorsEntrepreneur FirstMerian Ventures
MultiplAI Health is developing an RNA-sequencing and AI-based whole blood screening test to detect complex diseases, with a focus on cardiovascular disorders and cancer.
AI & Machine LearningBiotechDigital Health
Parallel Health offers a skincare product line addressing aging through microbiome science, including peptide creams and cleansers designed to target the hallmarks of skin aging.
BiotechConsumerDigital HealthDirect to ConsumerHealthtechWellness & Fitness
Nathan Brown(Founder)in
Co-investorsAxial VCHyphen Capital
Stem Pharm develops therapeutics using stem cell technology for disease treatment and drug discovery.
BiotechDeep TechHealthtechMedical DevicesNew MaterialsMadison, US
Connie Lebakken(COO)inBill Murphy(CSO)inSteven Visuri(CEO)inRyan Gordon(Sr. V.P. of Business Development and Commercialization)in
Tailor Bio develops targeted cancer therapies for tumors characterized by chromosomal instability, working in the field of precision oncology.
BiotechHealthtech
Co-investorsJIC Venture Growth InvestmentsANRINew Enterprise Associates (NEA)Spiral CapitalY Combinator
Yali develops fermentation technology to produce sustainable fats and lipids for alternative dairy products like ice cream, butter, and milk, using fewer inputs than conventional sources.
BiotechCleantechClimate TechFoodTech
Co-investorsFTW VenturesS2G InvestmentsCRCM VenturesThird Kind Venture Capital
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
AarogyaCognitivegeneticsDoloromicsEpicombiPrenomeWellsimbiotech
Exits · 2
1 IPOs · 1 acquisitions · showing 1HumacyteNASDAQ: HUMA
Portfolio news
latest coverage across their companiesflowscope · ycombinator.com · May 11, 2026
Antithesis · prnewswire.com · Dec 3, 2025
Frequently asked questions
- How many investments has First In Ventures made?
- First In Ventures has 30 tracked investments, 2 of which have exited, including 1 dated in the last 24 months.
- What stage does First In Ventures invest at?
- First In Ventures invests at the Pre-Seed, Seed stages.
- What is First In Ventures's typical check size?
- First In Ventures typically writes checks of $50K – $200K.
- What sectors does First In Ventures focus on?
- First In Ventures focuses on AI & Machine Learning, Biotech, Data & Infrastructure, Healthtech, Medical Devices.
- Where is First In Ventures located?
- First In Ventures is headquartered in Middletown, US.
- Does First In Ventures lead rounds?
- Yes, First In Ventures leads investment rounds.
- Who does First In Ventures co-invest with?
- First In Ventures most often shares deals with Better Ventures Central Llc, Illumina Ventures, Entrepreneur First, among 29 tracked co-investors.
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