Medicxi
Venture capitalLondon · Pre-Seed–Late Stage · 34 people tracked
Also known as MEDICXI VENTURES MANAGEMENT (JERSEY) LIMITED
Investment thesis
Medicxi invests in life sciences companies focused on drug discovery and development of therapeutics addressing unmet medical needs. The firm leverages deep domain expertise from its founders' 20+ year track record in the sector and manages a portfolio of investments alongside its institutional capital base, which includes support from major pharmaceutical and life sciences companies including GlaxoSmithKline, Johnson & Johnson, Novartis, and Verily.
Source: firm website, verified Aug 7, 2026.
Team · 34 people
from the firm's websiteWhat they invest in
from 10 of 29 portfolio companiesBiotech ×9AdTech ×1Enterprise Software ×1Healthtech ×1Medical Devices ×1SaaS ×1
HQs:United States×9
Investments · 29 tracked
founders shown can be your intro pathBiotechWaltham, US
Jan Van Heek(Director)Joseph Reilly(Executive Officer)Nico Vandervelpen(Director)Geoff Race(Executive Officer)Fred Ahlholm(Executive Officer)Remy Luthringer(Executive Officer, Director)
Board seatFrancesco De Rubertis· per SEC Form D · $31M raise · filed Mar 2015
BiotechSouth San Francisco, US
Tracy Saxton(Director)Grant E Pickering(Executive Officer, Director, Promoter)Jeff Fairman(Executive Officer)Ashish Khanna(Executive Officer)William Newell(Director)Kurt von Emster(Director)
Board seatMoncef Slaoui· per SEC Form D · $110M raise · filed Apr 2020
BiotechCambridge, US
Raj Parekh, Ph.D.(Director)Michael Wyzga(Executive Officer)Joel Jean-Mairet, Ph.D.(Director)Jose' Baselga, Ph.D.(Director)Dale Pfost, Ph.D.(Director)Alan E. Walts, Ph.D.(Director)
BiotechCollege Park, US
John Clerici(Executive Officer)Nicholas Williams(Director)Andrew Drechsler(Executive Officer)Seth Rudnick(Director)Jon Edwards(Director)Brett Giroir(Executive Officer, Director)
Board seatMoncef Slaoui· per SEC Form D · $75M raise · filed Feb 2026
Bothell, US
Board seatGiovanni MariggiMoncef Slaoui· per SEC Form D · $84.8M raise · filed Mar 2025
BiotechPhiladelphia, US
Kim Blackwell(Director)Michael Byrnes(Director)Erez Chimovits(Director)Giovanni Mariggi(Director)Dieter Weinand(Director)William Hinshaw(Executive Officer, Director)
Board seatGiovanni Mariggi· per SEC Form D · $46M raise · filed May 2025
BiotechHenrico, US
Timothy E Ladin(Executive Officer)Andrew N Fleischman(Executive Officer, Director)Maneka Mirchandaney(Director)Giovanni Mariggi(Director)Ted Love(Director)
Board seatGiovanni Mariggi· per SEC Form D · $69M raise · filed May 2026
BiotechCharlottesville, US
Allen Cunningham(Executive Officer, Director)Nancy Hargreaves(Executive Officer)Jayson Dallas(Executive Officer, Director)Shaharyar Khan(Executive Officer, Director)Patrick Enright(Director)
Board seatFrancesco De Rubertis· per SEC Form D · $57M raise · filed Jan 2025
BiotechDallas, US
Yisroel Brumer(Director)Jeff Sherman(Executive Officer)David Morgan(Executive Officer)Ken Samet(Director)Sol Barer(Director)Grant Verstandig(Director)
Board seatMoncef Slaoui· per SEC Form D · $120.7M raise · filed Mar 2024
PartnerGiovanni Mariggi· led
A therapeutics company developing checkpoint agonist antibodies for autoimmune disease treatment based on Oxford University research (exited August 2022).
PartnerGiovanni Mariggi· led
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.
Public market activity · per SEC filings
what is this? ⓘ11 insider ownership filings (Forms 3/4/5)
at Centessa Pharmaceuticals plc (CNTA), RAPT Therapeutics, Inc. (RAPT), Phathom Pharmaceuticals, Inc. (PHAT)
Files 13F institutional holdings reports · latest Apr 2026
From the firm's own SEC EDGAR filings — stakes and insider roles in public companies, typically portfolio companies after an IPO. Not a portfolio list published by the firm.
Frequently asked questions
- What stage does Medicxi invest at?
- Medicxi invests at the Pre-Seed, Seed, Series A, Series B, Series C, Growth, Late Stage stages.
- What sectors does Medicxi focus on?
- Medicxi focuses on Biotech, Digital Health, Medical Devices.
- Where is Medicxi located?
- Medicxi is headquartered in London, GB.
- Does Medicxi lead rounds?
- Medicxi typically participates in rounds rather than leading them.
Media · Podcasts & interviews
featuring the teamGateway to Translation Webinar: Dr Francesco De Rubertis - Medicxi - YouTube
Translation Manchester · Francesco De Rubertis
Fireside Chat Francesco de Rubertis, Co-Founder & Partner of Medicxi and Mike Ward, Clarivate - YouTube
Optimum Strategic Communications · Francesco De Rubertis
How risky is it to invest in biotech? Where are the opportunities? - Francesco De Rubertis, Medicxi - YouTube
SuperReturnTV · Francesco De Rubertis
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