Fundraising Fox

BioAdvance

Venture capital

Conshohocken · Pre-Seed–Late Stage · 16 people tracked

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Investment thesis

BioAdvance backs early-stage life-science companies in the U.S. Mid-Atlantic region with the potential to enhance human well-being and quality of life. Structured as an evergreen fund, it takes a long-term investment perspective and continues to grow and reinvest over time. Its portfolio companies span therapeutics, medical devices, diagnostics, and digital health, and collectively have attracted over $4.4 billion of external follow-on capital to support their growth.

Source: firm website, verified Aug 3, 2026.

Stage
Pre-Seed–Late Stage
Check
$500K – $1.5M
HQ
Conshohocken, Pennsylvania, US
Leads rounds
Leads
Instruments
Equity
Founded
2002
Last 12 months
2 investments
AUM
$80M
Tracked investments
60

Team · 16 people

from the firm's website & curated & public directories
Adam Glasofer· Entrepreneur-in-Residence
Jen Gilburg· Board of Directors; Deputy Secretary, Office of Technology & Entrepreneurship, PA DCED
Jonathan Epstein· Board of Directors; Dean of the School of Medicine and EVP of the Health System, University of Pennsylvania
Roy M. Rosen· Board of Directors; Partner, First Round Capital
Steven Nichtberger· Board of Directors; Chairman & CEO, Cabaletta Bio

What they invest in

from 28 of 60 portfolio companies

Biotech ×22Healthtech ×11Medical Devices ×9Deep Tech ×5Digital Health ×4SaaS ×3AdTech ×1AI & Machine Learning ×1

HQs:United States×25United Kingdom×1

Who they back

founder profiles across 13 portfolio companies
62%
solo founders
8 of 13 mapped founding teams

Founding team size:solo founder×82 founders×43 founders×1

Investments · 60 tracked

founders shown can be your intro path

By year:2026 · 22025 · 12024 · 12022 · 12018 · 12017 · 32015 · 12014 · 111 dated

ImmunomeNASDAQ: IMNM
Palvella TherapeuticsNASDAQ: PVLA

Co-investorsFrazier Life Sciences

Relmada TherapeuticsNASDAQ: RLMD

BiotechNew York, US

Sergio Traversa(Executive Officer, Director)Eliseo O. Salinas(President and Chief Scientific Officer)Douglas Beck(Chief Financial Officer)Charles Casamento(Director)Paul Kelly(Director)Maged Shenouda(Director)

Ribonovaribonova.com✓ verified

RiboNova is a biopharmaceutical company developing small molecule drugs and precision medicines targeting transfer RNA for the treatment of mitochondrial disease.

BiotechDeep TechMedical DevicesWynnewood, US

Co-investorsMilitia Hill Ventures

Accelerated Biosciencesacceleratedbio.comin𝕏

Accelerated Biosciences commercializes human trophoblast stem cells (hTSC) and derived platforms for therapeutic development, serving pharmaceutical and biotech partners seeking accelerated pathways to clinical products.

BiotechHealthtechMedical Devices

Acuity Pharmaceuticals
Allevi
Alteris
Annovis
Atalan

Nurse retention platform designed to identify risk up to 12 months in advance.

Bainbridge Healthbainbridgehealth.comin

Bainbridge Health provides software solutions for hospital pharmacy operations, including infusion safety analytics, IV formulation management, and drug library development.

Data & InfrastructureDigital HealthEnterprise SoftwareHealthtechMedical DevicesPhiladelphia, US

Sam Wilson(Executive Officer)Joseph Kaupp(Executive Officer, Director)Sean O'Neill(Executive Officer, Director)

BoardAmy Gallagher(Director)Shahram Hejazi(Director)Thomas Lynch(Director)

Co-investorsChestnut Street Ventures

BobcatBioFeb 2025

BiotechHummelstown, US

Stephen C. Rocamboli(Executive Officer, Director)Rifat Pamukcu(Director)Robert Towarnicki(Executive Officer, Director)Roger Sawhney(Director)

BoardTim Van Treuren(Director)John Fucci(Director)in

Co-investorsLife Sciences Greenhouse InvestmentsBios Partners

Ceptaris

Co-investorsOsage Venture Partners

Cohero Health

HealthtechNew York, US

Melissa P. Manice(Executive Officer, Director)Daniel Weinstein(Executive Officer, Director)

BoardSteve Agular(Director)Sean Kearney(Director)

Concarloconcarlo.comin𝕏Mar 2017

Concarlo Therapeutics develops cancer therapeutics that target CDK4/6-driven cell proliferation and CDK2-driven resistance, focusing on improving outcomes for cancer patients through novel approaches in p27 biology.

BiotechBrooklyn, US

Stacy Blain(Founder and CEO)LisaMarie Casey(President and Manager)

Co-investorsCreative Destruction Lab (CDL)Raptor Group

CrossBridge
Eliksa Therapeuticseliksa.comin𝕏

Eliksa Therapeutics develops innovative treatments for rare diseases with unmet medical needs.

BiotechDigital HealthMedical Devices

Co-investorsMilitia Hill VenturesBen Franklin Technology Partners

ENB Therapeuticsenbpharma.comin

ENB Therapeutics develops small molecules targeting the endothelin B receptor (ETBR) in the tumor microenvironment to treat drug-resistant cancers by restoring immune cell infiltration and promoting tertiary lymphoid organ formation.

BiotechHealthtechNew York, US

Sumayah Jamal(President, Co-founder & Chief Scientific Officer)Robert Schneider(Co-founder & Chair of Scientific Advisory Board)Sandy Harm(Chief Operating Officer)Fumitaka Mori(Director)Albert Sokol(Executive Officer)

BoardBarbara Schilberg(Director)

Co-investorsRemiges Ventures, Inc.

Halo Labs
hanimunehanimunetherapeutics.com

Hanimune Therapeutics develops therapeutics for food allergy prevention and tolerance support for pediatric and adult patients, drawing on immunological science and food protein research.

BiotechFoodTechHealthtechMedical Devices

Co-investorsRobin Hood Ventures

HealthQxMar 2015

King Of Prussia, US

William M Conlan(Executive Officer, Director)William Conlan(Executive Officer, Director)Mark McAdoo(Executive Officer, Director)MARK MCADOO(Executive Officer)

BoardDavid Tamburri(Director)Mike Kane(Director)

HueDx
ImmuneJul 2026 · $15.1M

Boston, US

Ariana Thacker(Executive Officer)

ImmunoGenesis
InfraScan
InnervaceAug 2022

BiotechNew York, US

Nader Halim(Executive Officer, Director)Althea Stillman(Executive Officer, Director)

BoardJonathan Leff(Director)David Greenwald(Director)in

Co-investorsDeerfield Management Company

Intezyne
IVIEW Therapeuticsiviewtherapeutics.comin

BiotechCranbury, US

Bo Liang(Executive Officer, Director)Houman Hemmati(Executive Officer, Director)Wei Wang(Executive Officer, Director)John J Baldwin(Director)Tao Du(Director)

BoardQi Zhu(Director)

KaloCytekalocyte.cominApr 2018

KaloCyte develops ErythroMer, a dried, shelf-stable artificial red blood cell for use in emergency and trauma care when stored blood is unavailable or in short supply.

BiotechDeep TechHealthtechMedical DevicesBaltimore, US

Allan Doctor(Co-Founder & CSO)inDipanjan Pan(Co-Founder, Chief Technical Officer)inPhilip Spinella(Co-Founder, Chief Medical Officer)inDaniel Getman(Director)Gregory Lanza(Director)

Co-investorsBioGenerator VenturesMaryland TEDCONYBC VenturesOld Line Capital PartnersTEDCO

Kayothera
Keriton LLCkeriton.comin

Keriton offers a software platform for neonatal and pediatric hospital settings that supports safe infant feeding practices, milk management (donor human milk, formula, and parental human milk), and family engagement through features like secure photo sharing, e-journaling, and clinician messaging.

BiotechDigital HealthHealthtechSaaSPhiladelphia, US

Vidur Shailendra Bhatnagar(Manager)

Co-investorsBroad Street AngelsDorm Room37 Angels

Ladder Bio
Latus

Gene therapy company; recently appointed Bethany Mancilla as Chief Business Officer.

Loudmarkloudmark.comin𝕏

Loudmark is a marketing and design agency that provides advertising, branding, graphic design, web development, event production, and packaging services to clients.

AdTechMarketing TechPeachtree City, US

Co-investorsFitz Gate Ventures

LumenVu
Mebias Discovery

BiotechPhiladelphia, US

Shariff S. Bayoumy(Executive Officer)Brett A. Tounge(Executive Officer, Director)Lawrence C. Kuo(Executive Officer)Michael Serrano-Wu(Director)

BoardBarbara Schilberg(Director)

Melior Discoverymeliordiscovery.comin𝕏

Melior Discovery provides in vivo pharmacology services and phenotypic screening platforms for pharmaceutical and biopharmaceutical companies to evaluate candidate therapeutics in animal disease models.

AI & Machine LearningBiotechDeep TechHealthtechMedical Devices

Andrew Reaume(President and CEO, Co-Founder)Andrew Reaume, PhD, MBA(President and CEO, Co-Founder)

Midway PharmaceuticalsApr 2017

BiotechSpring House, US

Rifat Pamukcu(Executive Officer, Director)

BoardHarry Arader(Director)

Novira TherapeuticsDec 2014

BiotechDoylestown, US

Osvaldo Flores(Executive Officer, Director)Daniel E. Geffken(Executive Officer)George Hartman(Executive Officer)Gregory Korbel(Executive Officer)

BoardTim Shannon(Director)Scott Rocklage(Director)

Co-investorsCanaan Partners5AM VenturesVersant Ventures

NuPathe
Oncora Medical

Co-investorsCota Capital

Onspira Therapeutics

BiotechWayne, US

Roy Levitt(Executive Officer, Director)Stephen Tullman(Executive Officer, Director)Paul Barone(Executive Officer, Director)Brian Lortie(Executive Officer, Director)Douglas Gessl(Executive Officer)

OpsidioSep 2017

BiotechBryn Mawr, US

Martin D. Phillips(Executive Officer, Director)Nicholas W. Lukacs(Director)Frank Marcoux(Director)Alan E. Casnoff(Director)

Ossianixossianix.co.uk

Ossianix develops TXP1, a brain-selective shuttle based on a deimmunised VNAR antibody scaffold that targets TfR1 to carry therapeutic payloads across the blood-brain barrier.

BiotechDeep TechHealthtech

Frank S Walsh(CEO (Founder))J Lynn Rutkowski(CSO (Founder))Steve Moore(COO)Pawel Stocki(VP Research)

Phrase Healthphrasehealth.comin

Phrase Health provides analytics tools for health systems to reduce unwarranted clinical variation within the electronic health record (EHR), aiming to lower costs and improve patient outcomes.

Digital HealthHealthtechSaaSPhiladelphia, US

Marc Tobias, MD, FAMIA(Founder)inMichael Zeidlhack(Executive Officer, Director)Marc Tobias(Founder)inNaveen Muthu(Director)in

Co-investorsLionBird

Pillo

New York, US

Emanuele Musini(CEO and Director)James Wyman(CFO and Director)

BoardYogendra Jain(Director)

Co-investorsHackensack Meridian Health Bear's Den

Protez Pharmaceuticals
Renovacorrenovacorinc.comin

BiotechGreenwhich, US

Wendy DiCicco(Ms. DiCicco is the Secretary and Treasurer of the Issuer.)Arthur Feldman(Director)Magdalene Cook(Executive Officer, Director)Campbell Murray(Director)Edward J. Benz, Jr.(Director)Thomas Needham(Director)

Co-investorsElysia Capital

Ride Health
Senzo
Strados
The One Health Company
Tolerancetolerance.appOct 2024

Tolerance is a compliance platform that runs continuous automated checks against the NIST 800-171 standard and collects assessor-ready evidence for teams handling Controlled Unclassified Information (CUI).

CybersecurityGovTechSaaS

Co-investorsDorm RoomAmadeus Capital PartnersBen Franklin Technology PartnersColumbus Venture PartnersCriteria Bio VenturesEast Innovate+4 more

Tolerance Biotolerancebio.cominJun 2026

BiotechPhiladelphia, US

Francisco Leon(Executive Officer, Director)Philip Ball(Executive Officer, Director)Justin Vogel(Executive Officer, Director)

BoardDamia Tormo Carulla(Director)Pablo Cironi(Director)inRobert Goldstein(Director)

Co-investorsCriteria Bio Ventures

Treventis
Venatorx Pharmaceuticals

Developing ceftibuten-ledaborbactam etzadroxil, a clinical phase 3-ready oral beta-lactam/beta-lactamase inhibitor combination for complicated urinary tract infections.

Malvern, US

Co-investorsAMR Action FundForesite Capital

Vesteck</a> (Copy)vesteck.comin

Vesteck develops medical device technology in the cardiovascular/endovascular space.

HealthtechMedical DevicesWest Chester, US

JOSEPH W. RAFFERTY(Executive Officer, Director, Promoter)Rafferty Joseph(Executive Officer, Director)Edward Wulfman(Executive Officer)John Edoga(Director)JOHN DIEDERICH(Director)THIERRY RICHARD(Director)

Co-investorsNew World AngelsOcean Azul PartnersRobin Hood Ventures

Vittoriabiovittoriabio.comin

Vittoria develops immunotherapies, specifically CAR T-cell therapies, to treat difficult-to-treat diseases including cancers beyond B-cell types.

BiotechDeep TechMedical Devices

Co-investorsGlobal BioAccess FundAgent Capital

Wellsheet

Exits · 3

IPOs and acquisitions across the tracked portfolio

ImmunomeNASDAQ: IMNMPalvella TherapeuticsNASDAQ: PVLARelmada TherapeuticsNASDAQ: RLMD

Portfolio news

latest coverage across their companies

Frequently asked questions

How many investments has BioAdvance made?
BioAdvance has 57 tracked investments, including 1 dated in the last 24 months.
What stage does BioAdvance invest at?
BioAdvance invests at the Pre-Seed, Seed, Series A, Late Stage stages.
What is BioAdvance's typical check size?
BioAdvance typically writes checks of $500K – $1.5M.
What sectors does BioAdvance focus on?
BioAdvance focuses on Biotech, Digital Health, Healthtech, Longevity, Medical Devices.
Where is BioAdvance located?
BioAdvance is headquartered in Conshohocken, US.
Does BioAdvance lead rounds?
Yes, BioAdvance leads investment rounds.
Who does BioAdvance co-invest with?
BioAdvance most often shares deals with Militia Hill Ventures, Robin Hood Ventures, BioGenerator Ventures, among 28 tracked co-investors.

Media · Podcasts & interviews

featuring the team

Shahram Hejazi & Rick Jones of BioAdvance - 2020 Speaker Series - January 30th

Jefferson Innovation · Shahram Hejazi

Images

BioAdvance photo

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