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BioAdvance

Venture capital

Conshohocken · Pre-Seed–Late Stage · 19 people tracked

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Investment thesis

BioAdvance backs early-stage life-science companies in the U.S. Mid-Atlantic region with the potential to enhance human well-being and quality of life. Structured as an evergreen fund, it takes a long-term investment perspective and continues to grow and reinvest over time. Its portfolio companies span therapeutics, medical devices, diagnostics, and digital health, and collectively have attracted over $4.4 billion of external follow-on capital to support their growth.

Source: firm website, verified Sep 27, 2026.

Stage
Pre-Seed–Late Stage
Check
$500K – $1.5M
HQ
Conshohocken, Pennsylvania, US
Leads rounds
Leads
Instruments
Equity
Founded
2002
Last 12 months
3 investments
AUM
$80M
Tracked investments
67
IPOs
4
Acquisitions
1

Team · 19 people

from the firm's website & curated & public directories
Adam Glasofer· Entrepreneur-in-Residence
Jonathan Epstein· Board of Directors; Dean of the School of Medicine and EVP of the Health System, University of Pennsylvania
Philip P. Gerbino· Board of Directors; President Emeritus, University of the Sciences
Roy M. Rosen· Board of Directors; Partner, First Round Capital

What they invest in

from 45 of 67 portfolio companies

Biotech ×34Healthtech ×23Medical Devices ×13Digital Health ×9Deep Tech ×8AI & Machine Learning ×7SaaS ×4Cybersecurity ×2

HQs:United States×39United Kingdom×1Italy×1

Who they back

founder profiles across 24 portfolio companies
63%
solo founders
15 of 24 mapped founding teams
19%
repeat founders
of 16 founders with career history
~2 yrs
old at investment
median across 14 dated deals

Founding team size:solo founder×152 founders×83 founders×1

Where their founders studiedfrom 18 founders with education data

Princeton University ×3The Wharton School ×3University of Pennsylvania ×3

What their founders studiedfrom 17 founders with field-of-study data

Life Sciences ×7Economics ×4Computer Science ×3Business & Management ×2Medicine ×2

Where their founders worked beforefrom 16 founders with career history

Harvard John A. Paulson School of Engineering and Applied Sciences ×2

Investments · 67 tracked

founders shown can be your intro path

By year:2026 · 32025 · 12024 · 12023 · 12022 · 32021 · 12020 · 12019 · 12018 · 22017 · 52016 · 12015 · 123 dated

Immunomeimmunome.comin𝕏NASDAQ: IMNM

Immunome is a clinical-stage oncology company developing targeted cancer therapies, including antibody-drug conjugates (ADCs) and small molecules, to address unmet medical needs in cancers such as lymphoma and bladder cancer.

BiotechHealthtechExton, US

Scott K. Dessain(Executive Officer, Director)inDennis H Giesing(Executive Officer)inCorleen Roche(Executive Officer)inMichael J Morin(Executive Officer)Purnanand Sarma(Executive Officer, Director)inGeorge Hobbs(Executive Officer)

Co-investorsDelaware Crossing Investor GroupEvolution VC PartnersMilitia Hill VenturesPivotal Life SciencesRobin Hood VenturesT. Rowe Price

Palvellatxpalvellatx.comin𝕏NASDAQ: PVLA

Palvella Therapeutics develops QTORIN™, a targeted topical formulation of rapamycin designed to treat rare skin diseases including microcystic lymphatic malformations and cutaneous venous malformations by delivering the active ingredient to the dermal layers with minimal systemic absorption.

BiotechDigital HealthHealthtechMedical DevicesWayne, US

Wesley H. Kaupinen(President, Chief Executive Officer and Director)Matthew E. Korenberg(Chief Financial Officer, Treasurer and Secretary)inKathleen Goin(Chief Operating Officer)inJeffrey Martini(Chief Scientific Officer)inAshley Kline(Chief Commercial Officer)in

Co-investorsFrazier Life SciencesSamsara BioCapitalAgent Capital

QR Pharmaqrpharma.comNYSE: ANVS

QR Pharma is a clinical-stage biopharmaceutical company developing buntanetap, an orally administered small molecule that inhibits the synthesis of multiple neurotoxic proteins implicated in Alzheimer's disease and Parkinson's disease.

BiotechBerwyn, US

Maria Maccecchini(Executive Officer, Director)

BoardDhesh Govender(Director)Michael Hoffman(Director)Franz F. Hefti(Director)

Co-investorsKeiretsu ForumBen Franklin Technology PartnersRobin Hood Ventures

Relmada Therapeuticsrelmada.comNASDAQ: RLMD

Relmada is a clinical-stage biopharmaceutical company developing therapies including NDV-01, a sustained-release intravesical formulation of gemcitabine and docetaxel for non-muscle invasive bladder cancer, and Sepranolone, a candidate targeting compulsive behaviors via GABAA receptor modulation.

BiotechHealthtechNew York, US

Sergio Traversa(Executive Officer, Director)Paul Kelly(Director)Maged Shenouda(Director)inEliseo O. Salinas(President and Chief Scientific Officer)inDouglas Beck(Chief Financial Officer)Charles Ence(Chief Accounting and Compliance Officer)

Co-investorsBAM ElevateBraidwellCommodore CapitalJanus Henderson InvestorsOrbiMedRA Capital+2 more

Ribonovaribonova.com✓ verified

RiboNova is a biopharmaceutical company developing small molecule drugs and precision medicines targeting transfer RNA for the treatment of mitochondrial disease.

BiotechDeep TechMedical DevicesWynnewood, US

Co-investorsMilitia Hill Ventures

Accelerated Biosciencesacceleratedbio.comin𝕏

Accelerated Biosciences commercializes human trophoblast stem cells (hTSC) and derived platforms for therapeutic development, serving pharmaceutical and biotech partners seeking accelerated pathways to clinical products.

BiotechHealthtechMedical Devices

Atalanatalantech.cominMay 2023

Atalan Tech develops clinician retention intelligence solutions for healthcare systems and organizations seeking to identify at-risk clinicians early, understand underlying causes of burnout and turnover, and implement targeted interventions to improve workforce sustainability.

AI & Machine LearningDigital HealthEnterprise SoftwareHealthtechHR TechCalifornia, US

Tiffany ChaninSisi HuinTim Russo(Senior Healthcare Technology Executive)inSteven Strongwater(Director)Bob Saunders(Director)B. Bobby Bahram(Director)

Co-investorsBroad Street AngelsEarly Light VenturesExcelerate Health VenturesVTC VenturesOCA Ventures

Bainbridge Healthbainbridgehealth.cominJun 2018 · $1.6M

Bainbridge Health provides software solutions for hospital pharmacy operations, including infusion safety analytics, IV formulation management, and drug library development.

Data & InfrastructureDigital HealthEnterprise SoftwareHealthtechMedical DevicesPhiladelphia, US

Sam Wilson(Executive Officer)inJoseph Kaupp(Executive Officer, Director)Sean O'Neill(Executive Officer, Director)

BoardAmy Gallagher(Director)Shahram Hejazi(Director)Thomas Lynch(Director)

Co-investorsAlumni VenturesChestnut Street Ventures

Concarloconcarlo.comin𝕏Mar 2017

Concarlo Therapeutics develops cancer therapeutics that target CDK4/6-driven cell proliferation and CDK2-driven resistance, focusing on improving outcomes for cancer patients through novel approaches in p27 biology.

BiotechBrooklyn, US

Stacy Blain(Founder, CEO)inLisaMarie Casey(President and Manager)

BoardJason Mraz(Executive Board Member)in

Co-investorsCreative Destruction Lab (CDL)Raptor Group

Eliksa Therapeuticseliksa.comin𝕏Nov 2022

Eliksa Therapeutics develops innovative treatments for rare diseases with unmet medical needs.

BiotechDigital HealthMedical Devices

Co-investorsMilitia Hill VenturesBen Franklin Technology Partners

ENB Therapeuticsenbpharma.comin

ENB Therapeutics develops small molecules targeting the endothelin B receptor (ETBR) in the tumor microenvironment to treat drug-resistant cancers by restoring immune cell infiltration and promoting tertiary lymphoid organ formation.

BiotechHealthtechNew York, US

Sumayah Jamal(President, Co-founder & Chief Scientific Officer)inRobert Schneider(Co-founder & Chair of Scientific Advisory Board)inSandy Harm(Chief Operating Officer)inFumitaka Mori(Director)Albert Sokol(Executive Officer)

BoardBarbara Schilberg(Director)

Co-investorsAvestria VenturesRemiges Ventures, Inc.

FidoCurefidocure.comin𝕏Seed

One Health operates a clinical trial platform using canine cancer data to accelerate and de-risk human oncology drug development.

AI & Machine LearningBiotechDigital HealthHealthtechMedical DevicesSan Francisco, US

Christina Lopes(Co-Founder & CEO)inBenjamin Lewis(Co-Founder)inchristina lopes(Founder)in

Co-investorsAndreessen HorowitzaVentureCivilization Ventures Management, LlcGlobal BrainIKJ CapitalMaC Venture Capital+13 more

hanimunehanimunetherapeutics.com

Hanimune Therapeutics develops therapeutics for food allergy prevention and tolerance support for pediatric and adult patients, drawing on immunological science and food protein research.

BiotechFoodTechHealthtechMedical Devices

Meenal Lele(Founder)in

Co-investorsRobin Hood Ventures

ImmunoGenesisimmunogenesis.comin

ImmunoGenesis is a clinical-stage immuno-oncology biopharmaceutical company developing immune therapies for immune-excluded tumors, which resist standard PD-1 blockade.

BiotechHealthtechMedical DevicesDoylestown, US

Michael A. Curran(Director)inJennifer Barlow(Executive Officer, Director)Clifford Stocks(Director)James Barlow(Executive Officer, Director)Jeremy Barton(Executive Officer)Federica O'Brien(Executive Officer)

Co-investors3Spoke CapitalAdit Ventures Management, LlcAngel Physicians FundCancer FocusService Provider CapitalTexas HALO Fund

InnervaceinAug 2022 · $40M

BiotechNew York, US

Nader Halim(Executive Officer, Director)Althea Stillman(Executive Officer, Director)

BoardJonathan Leff(Director)David Greenwald(Director)in

Co-investorsDeerfield Management Company

IVIEW Therapeuticsiviewtherapeutics.comin

BiotechCranbury, US

Bo Liang(Executive Officer, Director)Houman Hemmati(Executive Officer, Director)Wei Wang(Executive Officer, Director)John J Baldwin(Director)Tao Du(Director)

BoardQi Zhu(Director)

KaloCytekalocyte.cominApr 2018

KaloCyte develops ErythroMer, a dried, shelf-stable artificial red blood cell for use in emergency and trauma care when stored blood is unavailable or in short supply.

BiotechDeep TechHealthtechMedical DevicesBaltimore, US

Allan Doctor(Co-Founder & CSO)inDipanjan Pan(Co-Founder, Chief Technical Officer)inPhilip Spinella(Co-Founder, Chief Medical Officer)inDaniel Getman(Director)Gregory Lanza(Director)

Co-investorsBioGenerator VenturesDelaware Crossing Investor GroupMaryland TEDCONYBC VenturesOld Line Capital PartnersTEDCO+1 more

KayoTherakayothera.com

Kayo Therapeutics is a biotechnology company developing therapeutics, with a scientific and clinical focus that includes areas such as metabolic disease and oncology.

BiotechHealthtechSeattle, US

Mark Esposito(CSO, Co-Founder and Board Member)inYibin Kang(Chair, Scientific Advisory Board and Co-Founder)Kendall Mohler(Executive Officer, Director)Thong Q. Le(President and CEO, Board Member)Ian Howes(Chief Financial Officer)Merika Koday(COO and Board Member)in

Co-investors7G BioVenturesFoundation Venture Capital Group, LLC

Keriton LLCkeriton.comin

Keriton offers a software platform for neonatal and pediatric hospital settings that supports safe infant feeding practices, milk management (donor human milk, formula, and parental human milk), and family engagement through features like secure photo sharing, e-journaling, and clinician messaging.

BiotechDigital HealthHealthtechSaaSPhiladelphia, US

Vidur Shailendra Bhatnagar(Manager)

Co-investors37 AngelsBroad Street AngelsDorm Room

Latuslatusbio.cominMay 2026 · $97M

Latus develops gene therapy research and development capabilities leveraging cell and gene therapy expertise.

AI & Machine LearningBiotechDeep TechHealthtechPhiladelphia, US

Co-investorsHatch BioFund8VCDCVC (Data Collective)DCVC BioGaingelsKorea Development Bank+1 more

Latus Biolatus.bioin

Latus develops gene therapies based on novel AAV capsid variants matched to optimized routes of administration, aiming to target specific cell types and tissues to lower dose requirements, toxicity, and manufacturing costs.

AI & Machine LearningBiotechDeep Tech

Co-investors8VCDCVC (Data Collective)Modi Ventures

Loudmarkloudmark.comin𝕏

Loudmark is a marketing and design agency that provides advertising, branding, graphic design, web development, event production, and packaging services to clients.

AdTechMarketing TechPeachtree City, US

Co-investorsFitz Gate Ventures

Melior Discoverymeliordiscovery.comin𝕏

Melior Discovery provides in vivo pharmacology services and phenotypic screening platforms for pharmaceutical and biopharmaceutical companies to evaluate candidate therapeutics in animal disease models.

AI & Machine LearningBiotechDeep TechHealthtechMedical Devices

Andrew Reaume(President and CEO, Co-Founder)inAndrew Reaume, PhD, MBA(President and CEO, Co-Founder)

Oncora Medical, LLConcora.aiAug 2017

HealthtechWilmington, US

Christopher Berlind(Executive Officer, Director)inDavid Lindsay, Jr.(Executive Officer, Director)

BoardGary Kurtzman(Director)

Co-investorsCota CapitalDorm Room

Ossianixossianix.co.ukin

Ossianix develops TXP1, a brain-selective shuttle based on a deimmunised VNAR antibody scaffold that targets TfR1 to carry therapeutic payloads across the blood-brain barrier.

BiotechDeep TechHealthtech

Frank S Walsh(CEO (Founder))J Lynn Rutkowski(CSO (Founder))inSteve Moore(COO)inPawel Stocki(VP Research)in

Phrase Healthphrasehealth.comin

Phrase Health provides analytics tools for health systems to reduce unwarranted clinical variation within the electronic health record (EHR), aiming to lower costs and improve patient outcomes.

Digital HealthHealthtechSaaSPhiladelphia, US

Marc Tobias, MD, FAMIA(Founder)inMichael Zeidlhack(Executive Officer, Director)Marc Tobias(Founder)inNaveen Muthu(Director)in

Co-investorsLionBird

Pilloermit.itinMay 2019 · $11M

Ermit designs and manufactures connected hardware devices with embedded software and AI capabilities, serving companies building IoT and field-operated products.

CybersecurityHardwareIoTNew York, IT

Emanuele Musini(CEO and Director)James Wyman(CFO and Director)

BoardYogendra Jain(Director)

Co-investorsCivilization Ventures Management, LlcHackensack Meridian Health Bear's DenHikma VenturesSamsung VenturesStanley Ventures

Renovacorrenovacorinc.comin

BiotechGreenwhich, US

Wendy DiCicco(Ms. DiCicco is the Secretary and Treasurer of the Issuer.)inArthur Feldman(Director)Magdalene Cook(Executive Officer, Director)Campbell Murray(Director)Edward J. Benz, Jr.(Director)Thomas Needham(Director)in

Co-investorsBroadview VenturesElysia CapitalInnogest CapitalNew Leaf Venture PartnersNovartis Venture Fund

Ride Healthridehealth.comJan 2020 · $6.2M

Ride Health connects healthcare organizations with transportation services to ensure patients, particularly older adults and people with disabilities, can reliably access medical care.

B2B MarketplacesHealthtechLogistics & Supply ChainSaaSSan Francisco, US

Imran Cronk(Founder)inDaniel Faath(Executive Officer, Director)Michael Reardon(Executive Officer)Cindy Nguyen(Executive Officer)

BoardTodd Pietri(Director)inSamir Malik(Director)

Co-investorsExcelerate Health VenturesTopmark PartnersActivate Venture PartnersActivate VenturesBridge BankLeading Edge Ventures+2 more

Spirovantspirovant.comin𝕏

Spirovant is a gene therapy company developing treatments for cystic fibrosis and other respiratory diseases, including viral vector-based therapies for airway epithelia.

BiotechHealthtechPhiladelphia, US

Joan Lau(Co-founder & Chief Executive Officer)Eric Yuen(Co-founder & Chief Medical Advisor (former CMO))inJane Hollingsworth(Co-founder & Executive Chair of the Board)inRoland Kolbeck(Chief Scientific Officer & Co-owner)inEric Pastor(Chief Technology Officer)inDavid Whitwell(Chief Financial Officer)in

Co-investorsMilitia Hill Ventures

Strados Labsstradoslabs.comin𝕏

Strados Labs builds wearable biosensors and a cloud platform that continuously capture and analyze respiratory data — including cough, spirometry, FeNO, and eCOA endpoints — in patients' daily lives.

AI & Machine LearningBiotechDigital HealthMedical DevicesPhiladelphia, US

Nick Delmonico(CEO & Co-founder)Yu Kan Au(Clinician Co-founder)Richard Powers(Executive Officer, Director)Steve Bishop(Director)Robert Ball(Director)Alex Levit(Director)

Co-investorsBand of AngelsBrincBroad Street AngelsCathexis VenturesNeer Venture PartnersNextFab Ventures+3 more

Tolerancetolerance.appOct 2024

Tolerance is a compliance platform that runs continuous automated checks against the NIST 800-171 standard and collects assessor-ready evidence for teams handling Controlled Unclassified Information (CUI).

CybersecurityGovTechSaaS

Co-investorsDorm RoomAmadeus Capital PartnersBen Franklin Technology PartnersColumbus Venture PartnersCriteria Bio VenturesEast Innovate+5 more

Tolerance Biotolerancebio.cominJun 2026

Tolerance Bio develops therapeutics targeting the thymus—the regulator of immune tolerance—to preserve, restore, and manipulate its function and extend health span.

BiotechDeep TechLongevityPhiladelphia, US

Francisco Leon(Executive Officer, Director)inPhilip Ball(Executive Officer, Director)Justin Vogel(Executive Officer, Director)in

BoardDamia Tormo Carulla(Director)Pablo Cironi(Director)inRobert Goldstein(Director)

Co-investorsCriteria Bio VenturesBen Franklin Technology PartnersColumbus Venture Partners

VENATORX PHARMACEUTICALS INCvenatorx.com

Developing ceftibuten-ledaborbactam etzadroxil, a clinical phase 3-ready oral beta-lactam/beta-lactamase inhibitor combination for complicated urinary tract infections.

BiotechMalvern, US

Christopher J. Burns(Executive Officer, Director)Daniel C. Pevear(Executive Officer)Michael Diem(Director)Vincent J. Milano(Director)Ezra Felker(Executive Officer)Shelley Chu(Director)

Co-investorsAMR Action FundForesite CapitalVersant Ventures

Vesteck</a> (Copy)vesteck.comin

Vesteck develops medical device technology in the cardiovascular/endovascular space.

HealthtechMedical DevicesWest Chester, US

JOSEPH W. RAFFERTY(Executive Officer, Director, Promoter)inRafferty Joseph(Executive Officer, Director)inEdward Wulfman(Executive Officer)John Edoga(Director)JOHN DIEDERICH(Director)THIERRY RICHARD(Director)

Co-investorsNew World AngelsOcean Azul PartnersRobin Hood Ventures

Vittoria Biotherapeutics, Incvittoriabio.cominJul 2021

Vittoria develops immunotherapies, specifically CAR T-cell therapies, to treat difficult-to-treat diseases including cancers beyond B-cell types.

BiotechDeep TechMedical DevicesPhiladelphia, US

Nicholas Siciliano(Director)inPreston Noon(Executive Officer)

BoardGeeta Vemuri(Executive Officer, Director)Bruce Peacock(Executive Officer, Director)Leon Moulder(Director)

Co-investorsAgent CapitalGlobal BioAccess FundHatch BioFund

Wellsheetwellsheet.comin𝕏Oct 2017

Wellsheet builds a clinical workflow support system that uses machine learning to predict physicians' information needs and present a structured, comprehensive view of patient data at the point of care.

AI & Machine LearningDigital HealthHealthtechNew York, US

Craig Limoli(Executive Officer, Director, Promoter)inDaniel Larkin(Executive Officer, Director, Promoter)

Co-investorsBeni Venture CapitalReal-Life InnovationsREDO VenturesSpringTide VenturesNewark Venture PartnersNVP Capital

Other

Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.

Acuity PharmaceuticalsAggamin BiologicsAlleviAlterisAnnovisAvid RadiopharmaceuticalsBobcatBioCeptarisCohero HealthCrossBridgeHalo LabsHealthQxHueDxImmuneInfraScanIntezyneLadder BioLumenVuMebias DiscoveryMidway PharmaceuticalsNovira TherapeuticsNuPatheOnspira TherapeuticsOpsidioPalvella TherapeuticsProtez PharmaceuticalsSenzoStradosThe One Health CompanyTreventis

Exits · 5

4 IPOs · 1 acquisitions

ImmunomeNASDAQ: IMNMPalvellatxNASDAQ: PVLAQR PharmaNYSE: ANVSRelmada TherapeuticsNASDAQ: RLMDNovira Therapeuticsacq. by Johnson & Johnson (Janssen)

Portfolio news

latest coverage across their companies

Frequently asked questions

How many investments has BioAdvance made?
BioAdvance has 67 tracked investments, 5 of which have exited, including 5 dated in the last 24 months.
What stage does BioAdvance invest at?
BioAdvance invests at the Pre-Seed, Seed, Series A, Late Stage stages.
What is BioAdvance's typical check size?
BioAdvance typically writes checks of $500K – $1.5M.
What sectors does BioAdvance focus on?
BioAdvance focuses on Biotech, Digital Health, Healthtech, Longevity, Medical Devices.
Where is BioAdvance located?
BioAdvance is headquartered in Conshohocken, US.
Does BioAdvance lead rounds?
Yes, BioAdvance leads investment rounds.
Who does BioAdvance co-invest with?
BioAdvance most often shares deals with Robin Hood Ventures, Broad Street Angels, Militia Hill Ventures, among 67 tracked co-investors.

Media · Podcasts & interviews

featuring the team

Shahram Hejazi & Rick Jones of BioAdvance - 2020 Speaker Series - January 30th

Jefferson Innovation · Shahram Hejazi

Images

BioAdvance photo

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