BioAdvance
Venture capitalConshohocken · Pre-Seed–Late Stage · 16 people tracked
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Investment thesis
BioAdvance backs early-stage life-science companies in the U.S. Mid-Atlantic region with the potential to enhance human well-being and quality of life. Structured as an evergreen fund, it takes a long-term investment perspective and continues to grow and reinvest over time. Its portfolio companies span therapeutics, medical devices, diagnostics, and digital health, and collectively have attracted over $4.4 billion of external follow-on capital to support their growth.
Source: firm website, verified Aug 3, 2026.
Team · 16 people
from the firm's website & curated & public directoriesWhat they invest in
from 36 of 63 portfolio companiesBiotech ×26Healthtech ×18Medical Devices ×11Deep Tech ×6Digital Health ×6SaaS ×4AI & Machine Learning ×2Cybersecurity ×2
HQs:United States×32United Kingdom×1Italy×1
Who they back
founder profiles across 13 portfolio companiesFounding team size:solo founder×82 founders×43 founders×1
Investments · 63 tracked
founders shown can be your intro pathBy year:2026 · 22025 · 12024 · 12022 · 32021 · 12020 · 12018 · 12017 · 32015 · 12014 · 12011 · 116 dated
Immunome develops oncology therapies, including varegacestat, an oral gamma secretase inhibitor in late-stage development for desmoid tumors, and antibody-drug conjugates and radioligand therapies in earlier clinical stages targeting various cancer indications.
Clay Siegall(President, Chief Executive Officer and Chairman)
Palvella Therapeutics develops QTORIN™, a targeted topical formulation of rapamycin designed to treat rare skin diseases including microcystic lymphatic malformations and cutaneous venous malformations by delivering the active ingredient to the dermal layers with minimal systemic absorption.
BiotechDigital HealthHealthtechMedical DevicesWayne, US
Wesley H. Kaupinen(President, Chief Executive Officer and Director)Matthew E. Korenberg(Chief Financial Officer, Treasurer and Secretary)inKathleen Goin(Chief Operating Officer)inJeffrey Martini(Chief Scientific Officer)inAshley Kline(Chief Commercial Officer)in
Co-investorsFrazier Life SciencesSamsara BioCapitalAgent Capital
QR Pharma is a clinical-stage biopharmaceutical company developing buntanetap, an orally administered small molecule that inhibits the synthesis of multiple neurotoxic proteins implicated in Alzheimer's disease and Parkinson's disease.
BiotechBerwyn, US
Maria Maccecchini(Executive Officer, Director)
BoardDhesh Govender(Director)Michael Hoffman(Director)Franz F. Hefti(Director)
Co-investorsKeiretsu ForumBen Franklin Technology Partners
Relmada is a clinical-stage biopharmaceutical company developing therapies including NDV-01, a sustained-release intravesical formulation of gemcitabine and docetaxel for non-muscle invasive bladder cancer, and Sepranolone, a candidate targeting compulsive behaviors via GABAA receptor modulation.
BiotechHealthtechNew York, US
Sergio Traversa(Executive Officer, Director)Paul Kelly(Director)Maged Shenouda(Director)inEliseo O. Salinas(President and Chief Scientific Officer)inDouglas Beck(Chief Financial Officer)Charles Ence(Chief Accounting and Compliance Officer)
Co-investorsBAM ElevateBraidwellCommodore CapitalJanus Henderson InvestorsOrbiMedRA Capital+2 more
RiboNova is a biopharmaceutical company developing small molecule drugs and precision medicines targeting transfer RNA for the treatment of mitochondrial disease.
BiotechDeep TechMedical DevicesWynnewood, US
Co-investorsMilitia Hill Ventures
Accelerated Biosciences commercializes human trophoblast stem cells (hTSC) and derived platforms for therapeutic development, serving pharmaceutical and biotech partners seeking accelerated pathways to clinical products.
BiotechHealthtechMedical Devices
Bainbridge Health provides software solutions for hospital pharmacy operations, including infusion safety analytics, IV formulation management, and drug library development.
Data & InfrastructureDigital HealthEnterprise SoftwareHealthtechMedical DevicesPhiladelphia, US
Sam Wilson(Executive Officer)inJoseph Kaupp(Executive Officer, Director)Sean O'Neill(Executive Officer, Director)
BoardAmy Gallagher(Director)Shahram Hejazi(Director)Thomas Lynch(Director)
Co-investorsChestnut Street Ventures
Concarlo Therapeutics develops cancer therapeutics that target CDK4/6-driven cell proliferation and CDK2-driven resistance, focusing on improving outcomes for cancer patients through novel approaches in p27 biology.
BiotechBrooklyn, US
Stacy Blain(Founder, CEO)inLisaMarie Casey(President and Manager)
BoardJason Mraz(Executive Board Member)in
Co-investorsCreative Destruction Lab (CDL)Raptor Group
Eliksa Therapeutics develops innovative treatments for rare diseases with unmet medical needs.
BiotechDigital HealthMedical Devices
Co-investorsMilitia Hill VenturesBen Franklin Technology Partners
ENB Therapeutics develops small molecules targeting the endothelin B receptor (ETBR) in the tumor microenvironment to treat drug-resistant cancers by restoring immune cell infiltration and promoting tertiary lymphoid organ formation.
BiotechHealthtechNew York, US
Sumayah Jamal(President, Co-founder & Chief Scientific Officer)inRobert Schneider(Co-founder & Chair of Scientific Advisory Board)inSandy Harm(Chief Operating Officer)inFumitaka Mori(Director)Albert Sokol(Executive Officer)
BoardBarbara Schilberg(Director)
Co-investorsRemiges Ventures, Inc.
Hanimune Therapeutics develops therapeutics for food allergy prevention and tolerance support for pediatric and adult patients, drawing on immunological science and food protein research.
BiotechFoodTechHealthtechMedical Devices
Meenal Lele(Founder)in
Co-investorsRobin Hood Ventures
ImmunoGenesis is a clinical-stage immuno-oncology biopharmaceutical company developing immune therapies for immune-excluded tumors, which resist standard PD-1 blockade.
BiotechHealthtechMedical DevicesDoylestown, US
Michael A. Curran(Director)inJennifer Barlow(Executive Officer, Director)Clifford Stocks(Director)James Barlow(Executive Officer, Director)Jeremy Barton(Executive Officer)Federica O'Brien(Executive Officer)
Co-investorsAdit Ventures Management, LlcAngel Physicians FundService Provider CapitalTexas HALO Fund
BiotechNew York, US
Nader Halim(Executive Officer, Director)Althea Stillman(Executive Officer, Director)
BoardJonathan Leff(Director)David Greenwald(Director)in
Co-investorsDeerfield Management Company
BiotechCranbury, US
Bo Liang(Executive Officer, Director)Houman Hemmati(Executive Officer, Director)Wei Wang(Executive Officer, Director)John J Baldwin(Director)Tao Du(Director)
BoardQi Zhu(Director)
KaloCyte develops ErythroMer, a dried, shelf-stable artificial red blood cell for use in emergency and trauma care when stored blood is unavailable or in short supply.
BiotechDeep TechHealthtechMedical DevicesBaltimore, US
Allan Doctor(Co-Founder & CSO)inDipanjan Pan(Co-Founder, Chief Technical Officer)inPhilip Spinella(Co-Founder, Chief Medical Officer)inDaniel Getman(Director)Gregory Lanza(Director)
Co-investorsBioGenerator VenturesMaryland TEDCONYBC VenturesOld Line Capital PartnersTEDCO
Keriton offers a software platform for neonatal and pediatric hospital settings that supports safe infant feeding practices, milk management (donor human milk, formula, and parental human milk), and family engagement through features like secure photo sharing, e-journaling, and clinician messaging.
BiotechDigital HealthHealthtechSaaSPhiladelphia, US
Vidur Shailendra Bhatnagar(Manager)
Co-investors37 AngelsBroad Street AngelsDorm Room
Loudmark is a marketing and design agency that provides advertising, branding, graphic design, web development, event production, and packaging services to clients.
AdTechMarketing TechPeachtree City, US
Co-investorsFitz Gate Ventures
Melior Discovery provides in vivo pharmacology services and phenotypic screening platforms for pharmaceutical and biopharmaceutical companies to evaluate candidate therapeutics in animal disease models.
AI & Machine LearningBiotechDeep TechHealthtechMedical Devices
Andrew Reaume(President and CEO, Co-Founder)inAndrew Reaume, PhD, MBA(President and CEO, Co-Founder)
HealthtechWilmington, US
Christopher Berlind(Executive Officer, Director)inDavid Lindsay, Jr.(Executive Officer, Director)
BoardGary Kurtzman(Director)
Co-investorsCota CapitalDorm Room
Ossianix develops TXP1, a brain-selective shuttle based on a deimmunised VNAR antibody scaffold that targets TfR1 to carry therapeutic payloads across the blood-brain barrier.
BiotechDeep TechHealthtech
Frank S Walsh(CEO (Founder))J Lynn Rutkowski(CSO (Founder))inSteve Moore(COO)inPawel Stocki(VP Research)in
Phrase Health provides analytics tools for health systems to reduce unwarranted clinical variation within the electronic health record (EHR), aiming to lower costs and improve patient outcomes.
Digital HealthHealthtechSaaSPhiladelphia, US
Marc Tobias, MD, FAMIA(Founder)inMichael Zeidlhack(Executive Officer, Director)Marc Tobias(Founder)inNaveen Muthu(Director)in
Co-investorsLionBird
Ermit designs and manufactures connected hardware devices with embedded software and AI capabilities, serving companies building IoT and field-operated products.
CybersecurityHardwareIoTNew York, IT
Emanuele Musini(CEO and Director)James Wyman(CFO and Director)
BoardYogendra Jain(Director)
Co-investorsCivilization Ventures Management, LlcHackensack Meridian Health Bear's DenHikma VenturesSamsung VenturesStanley Ventures
BiotechGreenwhich, US
Wendy DiCicco(Ms. DiCicco is the Secretary and Treasurer of the Issuer.)inArthur Feldman(Director)Magdalene Cook(Executive Officer, Director)Campbell Murray(Director)Edward J. Benz, Jr.(Director)Thomas Needham(Director)in
Co-investorsElysia CapitalBroadview VenturesInnogest CapitalNew Leaf Venture PartnersNovartis Venture Fund
Ride Health connects healthcare organizations with transportation services to ensure patients, particularly older adults and people with disabilities, can reliably access medical care.
B2B MarketplacesHealthtechLogistics & Supply ChainSaaSSan Francisco, US
Imran Cronk(Founder)inDaniel Faath(Executive Officer, Director)Michael Reardon(Executive Officer)Cindy Nguyen(Executive Officer)
BoardTodd Pietri(Director)inSamir Malik(Director)
Co-investorsExcelerate Health VenturesActivate Venture PartnersActivate VenturesBridge BankLeading Edge VenturesNewark Venture Partners+2 more
Spirovant is a gene therapy company developing treatments for cystic fibrosis and other respiratory diseases, including viral vector-based therapies for airway epithelia.
BiotechHealthtechPhiladelphia, US
Joan Lau(Co-founder & Chief Executive Officer)Eric Yuen(Co-founder & Chief Medical Advisor (former CMO))inJane Hollingsworth(Co-founder & Executive Chair of the Board)inRoland Kolbeck(Chief Scientific Officer & Co-owner)inEric Pastor(Chief Technology Officer)inDavid Whitwell(Chief Financial Officer)in
Co-investorsMilitia Hill Ventures
Tolerance is a compliance platform that runs continuous automated checks against the NIST 800-171 standard and collects assessor-ready evidence for teams handling Controlled Unclassified Information (CUI).
CybersecurityGovTechSaaS
Co-investorsDorm RoomAmadeus Capital PartnersBen Franklin Technology PartnersColumbus Venture PartnersCriteria Bio VenturesEast Innovate+4 more
Tolerance Bio develops therapeutics targeting the thymus—the regulator of immune tolerance—to preserve, restore, and manipulate its function and extend health span.
BiotechDeep TechLongevityPhiladelphia, US
Francisco Leon(Executive Officer, Director)inPhilip Ball(Executive Officer, Director)Justin Vogel(Executive Officer, Director)in
BoardDamia Tormo Carulla(Director)Pablo Cironi(Director)inRobert Goldstein(Director)
Co-investorsCriteria Bio VenturesBen Franklin Technology PartnersColumbus Venture Partners
Vesteck develops medical device technology in the cardiovascular/endovascular space.
HealthtechMedical DevicesWest Chester, US
JOSEPH W. RAFFERTY(Executive Officer, Director, Promoter)inRafferty Joseph(Executive Officer, Director)inEdward Wulfman(Executive Officer)John Edoga(Director)JOHN DIEDERICH(Director)THIERRY RICHARD(Director)
Co-investorsNew World AngelsOcean Azul PartnersRobin Hood Ventures
Vittoria develops immunotherapies, specifically CAR T-cell therapies, to treat difficult-to-treat diseases including cancers beyond B-cell types.
BiotechDeep TechMedical DevicesPhiladelphia, US
Nicholas Siciliano(Director)inPreston Noon(Executive Officer)
BoardGeeta Vemuri(Executive Officer, Director)Bruce Peacock(Executive Officer, Director)Leon Moulder(Director)
Co-investorsAgent CapitalGlobal BioAccess Fund
Wellsheet builds a clinical workflow support system that uses machine learning to predict physicians' information needs and present a structured, comprehensive view of patient data at the point of care.
AI & Machine LearningDigital HealthHealthtechNew York, US
Craig Limoli(Executive Officer, Director, Promoter)inDaniel Larkin(Executive Officer, Director, Promoter)
Co-investorsBeni Venture CapitalReal-Life InnovationsREDO VenturesSpringTide VenturesNewark Venture PartnersNVP Capital
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
Acuity PharmaceuticalsAggamin BiologicsAlleviAlterisAnnovisAtalanAvid RadiopharmaceuticalsBobcatBioCeptarisCohero HealthCrossBridgeHalo LabsHealthQxHueDxImmuneInfraScanIntezyneKayotheraLadder BioLatusLumenVuMebias DiscoveryMidway PharmaceuticalsNovira TherapeuticsNuPatheOnspira TherapeuticsOpsidioProtez PharmaceuticalsSenzoStradosThe One Health CompanyTreventisVenatorx Pharmaceuticals
Exits · 5
4 IPOs · 1 acquisitionsImmunomeNASDAQ: IMNMPalvellatxNASDAQ: PVLAQR PharmaNYSE: ANVSRelmada TherapeuticsNASDAQ: RLMDNovira Therapeuticsacq. by Johnson & Johnson (Janssen)
Portfolio news
latest coverage across their companies
Relmada Therapeutics · fool.com · Aug 14, 2026
Tolerance · medscape.com · Aug 10, 2026

Tolerance Bio · intelligence360.news · Jul 28, 2026
Immune · biobuzz.io · Jul 13, 2026
Ossianix · stevenagecatalyst.com · Jul 7, 2026
Ride Health · crainsnewyork.com · Dec 23, 2025
IVIEW Therapeutics · bioadvance.com · Jul 26, 2025
Frequently asked questions
- How many investments has BioAdvance made?
- BioAdvance has 63 tracked investments, 5 of which have exited, including 4 dated in the last 24 months.
- What stage does BioAdvance invest at?
- BioAdvance invests at the Pre-Seed, Seed, Series A, Late Stage stages.
- What is BioAdvance's typical check size?
- BioAdvance typically writes checks of $500K – $1.5M.
- What sectors does BioAdvance focus on?
- BioAdvance focuses on Biotech, Digital Health, Healthtech, Longevity, Medical Devices.
- Where is BioAdvance located?
- BioAdvance is headquartered in Conshohocken, US.
- Does BioAdvance lead rounds?
- Yes, BioAdvance leads investment rounds.
- Who does BioAdvance co-invest with?
- BioAdvance most often shares deals with Militia Hill Ventures, Robin Hood Ventures, BioGenerator Ventures, among 29 tracked co-investors.
Media · Podcasts & interviews
featuring the teamShahram Hejazi & Rick Jones of BioAdvance - 2020 Speaker Series - January 30th
Jefferson Innovation · Shahram Hejazi
Images
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