DCVC Bio
Venture capitalPalo Alto · Seed–Growth · 15 people tracked
Investment thesis
DCVC Bio invests in founders marrying deep biological insight and engineering with large-scale computation to solve hard problems. Established in 2018, it backs foundational science and deep tech ventures across drug discovery (using synthetic biology, microfluidics, and machine learning to create novel therapies), agriculture (safer crop protection, reduced fertilizer use, renovated food systems), and bio-based alternative materials. The firm's team combines scientific expertise in genetics, chemistry, molecular biology, agriculture, industrial fermentation, and AI with decades of operational management experience, aiming to improve human health, make food production more sustainable, and slow climate change.
Source: firm website, verified Aug 3, 2026.
Team · 15 people
from the firm's websiteWhat they invest in
from 6 of 10 portfolio companiesBiotech ×4AI & Machine Learning ×2Deep Tech ×2Enterprise Software ×2Medical Devices ×2AgTech ×1Cleantech ×1Climate Tech ×1
HQs:United States×7
Investments · 10 tracked
founders shown can be your intro pathFervo Energy develops next-generation geothermal technology using advanced drilling and sensing techniques to unlock carbon-free, 24/7 power generation in previously uneconomic locations.
CleantechClimate TechEnergyHouston, US
Tim Latimer(Founder & CEO)inJack Norbeck(Founder)inDavid Thomas Danielson(Director)Nicholas Walrod(Director)Ion Yadigaroglu(Director)
BioCentury provides business intelligence, market analysis, and networking services for biotech and pharmaceutical industry leaders.
BiotechData & InfrastructureEnterprise SoftwareDurham, US
Pieter Burger(Executive Officer, Director)Thomas Kaiser(Executive Officer, Director)
BoardChristopher Meldrum(Executive Officer, Director)Dennis Langer(Director)
Board seatJohn Hamer· per SEC Form D · $70.7K raise · filed Oct 2025
Durham, US
Megan Phelan(Director)Stephen Van Helden(Director)Michele Fite(Executive Officer)Matthew Todd Rands(Executive Officer, Director)Chloe Pavely(Executive Officer)Paul Boyer(Executive Officer)
Board seatKiersten Stead· per SEC Form D · $25M raise · filed Jan 2024
San Diego, US
Board seatJohn Hamer· per SEC Form D · $55.2M raise · filed Mar 2023
Durham, US
Board seatKiersten Stead· per SEC Form D · $24.5M raise · filed Dec 2021
Umoja Biopharma develops in vivo CAR T cell therapies for cancer treatment using its VivoVec platform, which generates CAR T cells directly in patients' bodies.
BiotechDigital HealthMedical DevicesSeattle, US
Philip S. Low(Director)Irena Melnikova(Executive Officer)Anna French(Director)Robert Glassman(Director)John Hamer(Director)Luke Evnin(Director)
Board seatJohn Hamer· per SEC Form D
Unlearn develops AI-powered digital twins and data analytics tools to optimize clinical trial design and execution for pharmaceutical companies.
AI & Machine LearningBiotechDeep TechEnterprise Software
Charles Fisher(Founder & CEO)inAaron Smith(Founder)
Board seatJohn Hamer· per SEC Form D · $50M raise · filed Apr 2022
nChroma Bio develops in vivo targeted delivery and genetic engineering technologies for genetic medicine applications.
BiotechDeep TechMedical Devices
Luke Gilbert, PhDKeith Joung, MD, PhDDavid Liu, PhDAngelo Lombardo, PhDLuigi Naldini, MD, PhDJonathan Weissman, PhD
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.
Fund performance · per public LP disclosures
as of Nov 2025| Fund | Vintage | Committed | Net IRR | TVPI | DPI |
|---|---|---|---|---|---|
| DCVC Bio II, L.P.LPs: Employees' Retirement System of Rhode Island | 2020 | — | 3.5% | 1.07x | 0.21x |
Source: public limited-partner disclosures (CalPERS, CalSTRS). Net IRR / TVPI / DPI as reported by the limited partner; a fund's early-year IRR is an interim estimate (J-curve).
Frequently asked questions
- What stage does DCVC Bio invest at?
- DCVC Bio invests at the Seed, Series A, Series B, Series C, Growth stages.
- What sectors does DCVC Bio focus on?
- DCVC Bio focuses on Advanced Manufacturing, AgTech, AI & Machine Learning, Biotech, Climate Tech, Cybersecurity, Deep Tech, Defense Tech, Energy, Fintech, FoodTech, InsurTech, Longevity, New Materials, Quantum Computing, Space Tech.
- Where is DCVC Bio located?
- DCVC Bio is headquartered in Palo Alto, US.
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