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ARCH Venture PartnersFull Portfolio

185 tracked investments · listed companies and verified rows first

Prime Medicineprimemedicine.comin𝕏NASDAQ: PRME✓ verified

Prime Medicine develops one-time genetic therapies using Prime Editing, a gene editing technology developed in David R.

BiotechDeep TechHealthtechMedical Devices

Andrew Anzalone(Co-founder and Head of Platform)David Liu(Co-founder)Allan Reine(Chief Executive Officer)Mohammed Asmal(Chief Medical Officer)Ann Lee(Chief Technical Officer)Svetlana Makhni(Chief Financial Officer)

908 Devices908devices.comin𝕏NASDAQ: MASSApr 2015

908 Devices manufactures handheld mass spectrometry and chemical analysis devices for rapid detection in defense, security, and hazardous materials response applications.

Deep TechDefense TechHardwareMedical DevicesBoston, US

Kevin J. Knopp, PhD(CEO & Co-founder)J. Michael Ramsey(Director)Christopher Brown(Executive Officer)Joseph Griffith IV(Executive Officer)Corey Steffek(Director)Kevin Knopp(Executive Officer, Director)

Board seatKeith CrandellKevin Hrusovsky· per SEC Form D

Beam Therapeuticsbeamtx.comin𝕏NASDAQ: BEAMFeb 2018

Beam Therapeutics develops gene-editing medicines, particularly base editors and precision genome editing technologies, to create lifelong cures for patients with serious genetic diseases.

BiotechDeep TechMedical DevicesCambridge, US

David R. Liu(Founder and Inventor)J. Keith Joung(Founder and Inventor)Feng Zhang(Founder and Inventor)CAROLE HO(Director)John Evans(Executive Officer, Director)MARK FISHMAN(Director)

Board seatRobert NelsenKristina Burow· per SEC Form D

Boundless Bioboundlessbio.comin𝕏NASDAQ: BOLDMay 2021

Boundless Bio develops precision oncology medicines targeting ecDNA-amplified cancers, specifically creating a new category of ecDNA-directed therapies for patients with oncogenic alterations.

BiotechMedical DevicesLa Jolla, US

Benjamin Cravatt, Ph.D.(Director)Ho Sung Cho, Ph.D.(Director)Carolyn Ng, Ph.D.(Director)Jakob Loven, Ph.D.(Director)Zachary D. Hornby(Executive Officer, Director)Jonathan E. Lim, M.D.(Director)

Board seatKristina Burow· per SEC Form D

Enliven Therapeutics, Inc.NASDAQ: ELVNApr 2024SEC filingmedium confidence

Boulder, US

Board seatRichard Heyman· per SEC Form D · $90M raise · filed Apr 2024

Gossamer Biogossamerbio.comin𝕏NASDAQ: GOSSJan 2018

Gossamer Bio is a clinical-stage biopharmaceutical company developing seralutinib, an investigational drug candidate for treating pulmonary arterial hypertension and pulmonary hypertension associated with interstitial lung disease.

BiotechDigital HealthMedical DevicesSan Diego, US

Bryan Giraudo(Executive Officer)Faheem Hasnain(Executive Officer, Director)Russell Cox(Director)Renee Gala(Director)Laura Carter, Ph.D.(Executive Officer)Christian Waage(Executive Officer)

Board seatKristina BurowRobert Nelsen· per SEC Form D

GRAILgrail.comin𝕏NASDAQ: GRALMay 2018

GRAIL develops the Galleri blood test for multi-cancer early detection using next-generation sequencing and machine learning to screen for multiple deadly cancer types before symptoms appear.

AI & Machine LearningBiotechHealthtechMedical DevicesMenlo Park, US

Joshua Ofman, MD, MSHS(Chief Executive Officer)Aaron Freidin(Executive Officer)Josh Ofman(Executive Officer)Robert Ragusa(Executive Officer, Director)Jose Baselga(Director)Kaye Foster-Cheek(Director)

Board seatRobert Nelsen· per SEC Form D

Neumora Therapeuticsneumoratx.comin𝕏NASDAQ: NMRAJan 2023

Neumora is a clinical research company developing investigational medications, with a focus on conducting clinical trials to obtain regulatory approval and make treatments available to patients.

BiotechDeep TechDigital HealthMedical DevicesWatertown, US

Matthew Fust(Director)Kari Stefansson(Director)Joshua Pinto(Executive Officer)Maykin Ho(Director)Alaa Halawa(Director)Tamara Tompkins(Executive Officer)

Board seatRobert NelsenKristina Burow· per SEC Form D

Quanterixquanterix.comin𝕏NASDAQ: QTRXMar 2016

Quanterix develops technology for highly sensitive detection of protein biomarkers using non-invasive sample types, aimed at early disease detection and prevention.

BiotechDigital HealthHealthtechMedical DevicesLexington, US

John Connolly(Director)Douglas Cole(Director)David Walt(Director)Martin Madaus(Director)Dennis Sandstedt(Director)Ernest Orticerio(Executive Officer)

Board seatKeith Crandell· per SEC Form D

Scholar Rockscholarrock.comin𝕏NASDAQ: SRRKDec 2015

Scholar Rock is a biopharmaceutical company that develops therapies targeting growth factor proteins to treat serious diseases.

BiotechCambridge, US

Katrine Bosley(Director)Michael Gilman(Director)Nagesh Mahanthappa(Executive Officer, Director)Timothy Springer(Director)

BoardAmir Nashat(Director)

Board seatKristina Burow· per SEC Form D

Scholar Rock Holding Corp, Inc.NASDAQ: SRRKDec 2017SEC filingmedium confidence

Clinical-stage biopharmaceutical company focused on discovery and development of innovative medicines for serious diseases by targeting the Transforming Growth Factor Beta pathway.

BiotechCambridge, US

Alan Buckler(Executive Officer)Nagesh Mahanthappa(Executive Officer, Director)Timothy Springer(Director)David Hallal(Director)Michael Gilman(Director)Jeffrey Flier(Director)

Board seatKristina Burow· per SEC Form D · $47M raise · filed Jan 2018

Seaport Therapeuticsseaporttx.comin𝕏NASDAQ: SPTXOct 2024

Seaport Therapeutics develops therapeutics and medicines.

BiotechMental HealthBoston, US

Daphne Zohar(Founder, CEO and Board Member)Michael Chen(Executive Officer)Lana Gladstein(Executive Officer)Antony Loebel(Executive Officer)Eric Green(Executive Officer)

BoardJames I. Healy(Director)

Board seatRobert Nelsen· per SEC Form D

Twist Biosciencetwistbioscience.comin𝕏NASDAQ: TWSTMay 2015

Twist Bioscience develops a silicon-based synthetic DNA manufacturing platform that produces high-quality DNA, genes, and NGS reagents for customers in medicine, agriculture, and industrial chemicals.

BiotechDeep TechSemiconductorsSouth San Francisco, US

Emily Marine Leproust(Executive Officer, Director, Promoter)William Charles Banyai(Executive Officer, Director, Promoter)Bill James Peck(Executive Officer, Promoter)Rob Chess(Director)

BoardPaul Conley(Director)

Board seatKeith Crandell· per SEC Form D

Vir BiotechnologyNASDAQ: VIRJun 2018

San Francisco, US

Board seatRobert NelsenKristina BurowVicki Sato· per SEC Form D

Voyager Therapeutics, Inc.NASDAQ: VYGRJan 2024SEC filingmedium confidence

BiotechLexington, US

Steven Hyman(Director)James A. Geraghty(Director)Grace Colon(Director)Jude Onyia(Director)Robert W. Hesslein(Executive Officer)Todd Carter(Executive Officer)

Board seatGeorge Scangos· per SEC Form D · $20M raise · filed Jan 2024

Agios Pharmaceuticalsagios.comin𝕏NASDAQ: AGIO

Agios is a biopharmaceutical company developing therapies for rare diseases, with a primary focus on hemolytic anemias including pyruvate kinase deficiency, thalassemia, and sickle cell disease.

BiotechHealthtechMedical Devices

Denali Therapeuticsdenalitherapeutics.comNASDAQ: DNLIFeb 2024

Denali Therapeutics develops therapeutics for neurodegenerative diseases.

BiotechHealthtechMedical DevicesSan Francisco, US

Carole Ho(Executive Officer)Vicki L. Sato(Director)Nancy A. Thornberry(Director)Peter S. Klein(Director)Marc Tessier-Lavigne(Director)Jay T. Flatley(Director)

Erascaerasca.comin𝕏NASDAQ: ERASApr 2020

Erasca is a clinical-stage oncology company developing therapies targeting RAS- and MAPK pathway-driven cancers using a modality-agnostic approach including small molecules, large molecules, and protein degraders.

BiotechDeep TechDigital HealthMedical DevicesSan Diego, US

Pratik S. Multani, M.D.(Director)Valerie Harding-Start(Director)Jonathan E. Lim, M.D.(President and Executive Chairman)Gary Yeung, CFA(Chief Business Officer)Alexander W. Casdin(Director)James A. Bristol, Ph.D.(Director)

PartnerKristina Burow· quoted

Generate Biomedicinesgeneratebiomedicines.comin𝕏NASDAQ: GENB

Generate:Biomedicines develops protein-based therapeutics using artificial intelligence and machine learning in a field it calls Generative Biology, combining computational protein design with biological engineering.

AI & Machine LearningBiotechDeep TechSomerville, US

Gevorg Grigoryan(Co-Founder & Chief Technology Officer)

IlluminaNASDAQ: ILMN

Scalable, high throughput DNA sequencing platforms.

Kardigankardigan.bioinNASDAQ: KARD

Kardigan develops targeted cardiovascular treatments through a discovery and translational research platform, with a pipeline of late-stage drug candidates aimed at functional cures for cardiovascular disease.

AI & Machine LearningBiotechHealthtechMedical Devices

Kura Oncologykuraoncology.comNASDAQ: KURA

Kura Oncology is a company in the oncology/medtech sector that provides grant support for independent medical education programs designed to enhance healthcare professionals' ability to diagnose and treat patients in Kura Oncology's therapeutic areas of interest.

BiotechDigital HealthMedical DevicesLa Jolla, US

HEIDI HENSON(Executive Officer)TROY WILSON(Executive Officer, Director)ANNETTE NORTH(Executive Officer)PINGDA REN(Executive Officer)YI LIU(Executive Officer)ANTONIO GUALBERTO(Executive Officer)

Lyell ImmunopharmaNASDAQ: LYEL
Maze Therapeuticsmazetx.comin𝕏NASDAQ: MAZE

Maze Therapeutics develops precision medicines for kidney disease and other conditions with large unmet medical needs, using a genetic variant-based approach through its Compass platform.

BiotechMedical Devices

Parabilis Medicinesparabilismed.cominNASDAQ: PBLS

Helicons develops a peptide-based therapeutic platform designed to target intracellular proteins previously considered undruggable by combining the specificity of antibodies with the cell-penetrating properties of small molecules.

AI & Machine LearningBiotechDeep TechMedical Devices

Mathai Mammen(CEO, President and Chairman)

Perkinelmerperkinelmer.comin𝕏NYSE: RVTYSep 2021

PerkinElmer is a scientific instrument and technology company that provides analytical tools and services for research, diagnostics, and life sciences applications.

BiotechDeep TechEnterprise SoftwareHealthtechMedical DevicesWaltham, US

Sylvie Gregoire(Director)Michel Vounatsos(Director)Samuel Chapin(Director)James M. Mock(Executive Officer)Andrew Okun(Executive Officer)Pascale Witz(Director)

Rapport Therapeuticsrapportrx.cominNASDAQ: RAPP

Rapport is a biopharmaceutical company developing novel therapeutics.

BiotechHealthtechMedical Devices

Abe Ceesay(President)Cheryl GaultDr. Sevigny

Basking Biosciencesbaskingbiosciences.cominOct 2025✓ verified

Basking Biosciences develops therapeutics for thrombosis, vascular biology, and ischemic disease.

BiotechDigital HealthHealthtechMedical DevicesCary, US

Shahid Nimjee(Co-founder, Chief Scientific Officer and Stroke Clinical Lead)inBruce Sullenger(Co-founder)Julia Owens(Executive Officer, Director, Promoter)Ryan Helon(Director)Dan Myers(Director)Richard Shea(Executive Officer, Director, Promoter)

Board seatSteve Gillis· per SEC Form D

Cytrellis Biosystemscytrellis.cominJan 2021✓ verified

Cytrellis develops medical device technologies focused on aesthetic and reconstructive treatments, with expertise spanning dermatology, plastic surgery, and wound healing applications.

BiotechHealthtechMedical DevicesWoburn, US

Rox Anderson, MD(Founder, Medical / Technology Advisor)William G. Austen, Jr. MD(Founder, Medical / Technology Advisor)Doug Levinson, PhD(Founder)Denise Dajles, PhD(President & CEO)John McDonough(Executive Officer, Director)Keith Crandall(Director)

Board seatKeith Crandell· per SEC Form D

Vizgenvizgen.comin𝕏Jan 2026✓ verified

Vizgen develops spatial profiling instruments and reagents for high-throughput analysis of gene expression and protein distribution in tissue samples.

AI & Machine LearningBiotechDeep TechMedical DevicesCambridge, US

George Emanuel(Scientific Cofounder, VP & Portfolio Owner, Instruments)Jiang He(Scientific Cofounder, VP & Portfolio Owner, Reagents & Scientific Affairs)Robert Carson(Executive Officer, Director)Terry Lo(Director)Seth Benson(Executive Officer)Simona Levi(Executive Officer)

Board seatKeith Crandell· per SEC Form D

Aera Therapeuticsaeratx.comin𝕏✓ verified

Aera Therapeutics develops genetic medicines using next-generation delivery technologies and precision payloads optimized for specific diseases.

AI & Machine LearningBiotechDeep TechMedical Devices

Akin Akinc, Ph.D.(CEO)

Aspen Neuroscienceaspenneuroscience.comin𝕏✓ verified

Aspen Neuroscience develops iPSC-derived autologous cell therapies for neurological diseases, with a lead product (ANPD001) in Phase 1/2a clinical trials for Parkinson's disease.

BiotechDeep TechDigital HealthMedical Devices

Andrés Bratt-Leal(Co-Founder and Senior Vice President, Research & Development)Damien McDevitt(President and Chief Executive Officer)

Dewpoint Therapeuticsdewpointx.comin✓ verified

Dewpoint Therapeutics develops condensate-modulating drugs by using an integrated platform that maps, measures, and modulates biomolecular condensates to identify druggable targets and disease mechanisms.

AI & Machine LearningBiotechDeep TechBoston, US

Mark Murcko, Ph.D.(Director)Richard Young, Ph.D.(Director)Elisabeth Leiderman(Executive Officer)Ameet Nathwani, M.D.(Executive Officer, Director)Isaac Klein, M.D., Ph.D.(Executive Officer)Lori Escobedo(Executive Officer)

Lifordi Immunotherapeuticslifordi.com✓ verified

Lifordi Immunotherapeutics develops treatments for immunology and rare diseases through discovery, clinical development, and commercialization.

BiotechDeep TechHealthtech

Arthur O. Tzianabos, Ph.D.(President and CEO)Naina Bhasin, Ph.D.(Chief Business Officer)

Magnet Biomedicinemagnetbio.comin✓ verified

Magnet Biomedicine develops TrueGlue™, a molecular glue discovery platform for designing small molecule therapeutics that induce novel protein-protein interactions to treat cancer and immune disorders.

AI & Machine LearningBiotechMedical Devices

Benjamin F. Cravatt, PhD(Founder & Advisor)David A. Spiegel, MD, PhD(Founder & Advisor)Michael Rosbash, PhD(Founder & Advisor)Richa Saxena, PhD(Founder & Advisor)Stuart Schreiber, PhD(Founder & Advisor)

Moleculent ABmoleculent.comin𝕏✓ verified

Moleculent develops biological discovery and disease understanding tools for scientists.

AI & Machine LearningBiotechDeep Tech

Fredrik Roos(CTO & Co-founder)

Paradigm Healthparadigm.incin✓ verified

Paradigm Health operates a platform that increases patient access to clinical trials through a provider-facing infrastructure combined with AI-powered research technology.

AI & Machine LearningHealthtechMedical DevicesSaaS

Kent Thoelke(Founder and CEO)Jonathan Hirsch(Chief Strategy and Growth Officer)

Pretzel Therapeuticspretzeltx.comin✓ verified

Pretzel Therapeutics develops therapeutics targeting bioenergetic dysfunction and mitochondrial disease by addressing defects in mitochondrial DNA function and gene expression.

BiotechDeep TechHealthtechMedical Devices

Michal Minczuk(Co-Founder)Gabriel Martinez(Chief Scientific Officer & Co-Founder)Claes Gustafsson(Co-Founder)Maria Falkenberg(Co-Founder)Nils-Göran Larsson(Co-Founder)Jay Parrish(Chief Executive Officer & Chairman of the Board)

RhyGaze AGrhygaze.com✓ verified

RhyGaze develops gene therapies using optogenetic proteins to restore sight in patients with vision loss caused by retinal photoreceptor dysfunction.

BiotechDigital HealthMedical DevicesBasel, CH

Botond Roska(Researcher (M.D., Ph.D.))Bence György(IOB Assistant Professor & Head of Clinical Translation)Katherine High(CEO)

Tenvietenvie.com✓ verified

Tenvie is a clinical-stage biopharmaceutical company developing small molecule and biologic therapeutics for neurological and peripheral diseases.

BiotechMedical Devices

Tony Estrada(President & Chief Executive Officer)

Adesto TechnologiesAug 2013SEC filingmedium confidence

Sunnyvale, US

Narbeh Derhacobian(Executive Officer, Director)Barry Cox(Director)Matt Boyle(Director)Ron Shelton(Executive Officer)Alexei Andreev(Director)Nelson Chan(Director)

Board seatKeith Crandell· per SEC Form D · $12.5M raise · filed Sep 2015

Agbiomeagbiome.comAug 2015SEC filingmedium confidence

AgTechResearch Triangle Park, US

Scott Uknes(Manager)Larry Robbins(Secretary)Thomas Dietz(Manager)John Ryals(Manager)Paul Schulze-Lefert(President)Michael Koziel(Vice President and Manager)

Board seatKristina Burow· per SEC Form D · $34.5M raise · filed Aug 2015

Agrividaagrivida.comAug 2016

Agrivida develops enzyme technology for animal feed and nutrition, improving efficiency in poultry, swine, and other livestock production.

AgTechBiotechFoodTechMassachusetts, US

Rob Johnson(Director)R. Michael Raab(Executive Officer)Daniel Meagher(Executive Officer, Director)Mark Austin(Director)Robert Bucklin(Director)Jeremy Schley Johnson(Executive Officer)

Board seatClinton Bybee· per SEC Form D

AlzheonDec 2014SEC filingmedium confidence

BiotechFramingham, US

Martin Tolar, M.D., Ph.D.(President and Chief Executive Officer)Glenn E. Pauly(Chief Commercial Officer)Susan Abushakra, M.D.(Chief Medical Officer)John Hey, Ph.D.(Chief Scientific Officer)Kenneth A. Mace(Treasurer and Chief Financial Officer)Adem Albayrak(Chief Data Officer)

Board seatScott Minick· per SEC Form D · filed Feb 2015

Apex Neuro Holdings, Inc.Mar 2022SEC filingmedium confidence

Brooklyn, US

Zen Chu(Director)Lis Rhodes(Executive Officer)Francois Kress(Executive Officer, Director)

BoardAdam D'Augelli(Director)

Board seatRobert Nelsen· per SEC Form D · $10M raise · filed Mar 2022

Arbor Biotechnologiesarbor.bioin𝕏Nov 2021

Arbor develops programmable DNA editors for genetic medicine, aiming to enable functional cures for patients by addressing genetic diseases through bespoke gene editing approaches.

BiotechDigital HealthMedical DevicesCambridge, US

DAVID ARTHUR SCOTT(Executive Officer)WINSTON XIA YAN(Executive Officer)ANNIE HAZLEHURST(Director)FENG ZHANG(Director)

BoardDAVID R. WALT(Director)

Board seatKeith Crandell· per SEC Form D

Areteia Therapeuticsareteiatx.comFeb 2025

Areteia Therapeutics was a clinical-stage biotechnology company that is no longer operating.

BiotechChapel Hill, US

Robin Walker(Executive Officer)Christopher Courts(Executive Officer)Jorge Bartolome(Executive Officer, Director)

BoardBenjamin Gomez(Director)Adam Koppel(Director)Michael E. Bozik(Director)

Board seatPaul Berns· per SEC Form D

Arivalearivale.comMay 2017SEC filingmedium confidence

HealthtechSeattle, US

Nathan Price(Director)Tim Kilgallon(Director)Clayton Lewis(Executive Officer, Director)

Board seatRobert Nelsen· per SEC Form D · $30M raise · filed Jun 2017

Autobahn Therapeutics, Inc.autobahntx.cominAug 2024

Autobahn develops medicines for central nervous system (CNS) disorders by leveraging regenerative mechanisms of the human body.

BiotechDeep TechMedical DevicesSan Diego, US

Kevin Finney(Chairman, President and CEO)John Borkholder(Executive Officer)

BoardThomas Cahill(Director)Timothy Anderson(Director)Philip J DeSouza(Director)

Board seatKristina Burow· per SEC Form D

BoragenMar 2017SEC filingmedium confidence

Research Triangle Park, US

Tracy Jackson(Executive Officer)John Dombrosky(Executive Officer)Joel Marcus(Director)Stephen Benkovic(Director)Paul Schimmel(Director)

Board seatKristina Burow· per SEC Form D · $10.5M raise · filed Mar 2017

Cooledge LightingDec 2015SEC filingmedium confidence

Richmond

William Sims(Director)Kirk A. Washington(Director)Geoff Catherwood(Director)Thomas Bilbrough(Director)Calvin Wade Sheen(Executive Officer, Director)Jim Miller(Director)

Board seatClinton Bybee· per SEC Form D · $9.1M raise · filed Jan 2016

eGenesisegenesis.comFeb 2024

BiotechBrookline, US

Luhan Yang(President, Secretary and Treasurer)Geoff MacKay(Chief Executive Officer)

BoardGeorge M. Church(Director)

Board seatSteven Gillis· per SEC Form D

Elephas Bioscienceselephas.cominJan 2024

Elephas develops elive, a live-tissue platform technology that predicts immunotherapy response in cancer patients by measuring real-time immune activity in intact tumor tissue.

BiotechDigital HealthHealthtechMedical DevicesMadison, US

Michelle B. Arora(Director)Terrence P. Brady(Executive Officer)Jonathan Oliner(Executive Officer)Maneesh K. Arora(Executive Officer, Director, Promoter)

Board seatPaul Berns· per SEC Form D

Encentrio Therapeutics, Inc.Apr 2023SEC filingmedium confidence

BiotechSan Francisco, US

Thomas Hecht(Director)Sung Lee(Executive Officer, Director)Johanna Friedl-Naderer(Director)Natascha Schill(Executive Officer, Director)Vanina de Verneuil(Executive Officer)

Board seatGeorge Scangos· per SEC Form D · $400K raise · filed Apr 2023

Faraday Pharmaceuticalsfaradaypharma.comNov 2022

BiotechSeattle, US

Thomas King(Director)Brian Blackman(Executive Officer)Simon Tulloch(Executive Officer)Steven Gillis(Executive Officer, Director, Promoter)Mark Roth(Executive Officer, Director, Promoter)Stephen Hill(Executive Officer, Director)

Board seatSteven Gillis· per SEC Form D

High Plains Partners, LLCOct 2022SEC filingmedium confidence

AgTechVolga, US

Mark Hyde(Executive Officer)Gary Goplen(Director)Spencer Enninga(Director)Lewis Bainbridge(Director)Thomas J Kersting(Executive Officer)Mark Mickelson(Director)

Board seatRobert Nelsen· per SEC Form D · $230M raise · filed Oct 2022

IngredientWerksingredientwerks.comAug 2022SEC filingmedium confidence

IngredientWerks is a molecular farming company that engineers crops to produce animal-identical proteins as plant-based ingredients for the alternative protein food market.

AgTechBiotechFoodTechWoburn, US

Steve Snyder(Director)Clinton Bybee(Director)Ronald Warner Meeusen(Director)James Schultz(Director)Matthew Plavan(Executive Officer, Director)

Board seatClinton Bybee· per SEC Form D · $5M raise · filed Aug 2022

Insitroinsitro.comin𝕏Mar 2020

insitro is a drug discovery and development company that uses machine learning and cellular data to identify therapeutic insights and accelerate the creation of new medicines.

AI & Machine LearningBiotechSouth San Francisco, US

Daphne Koller(CEO & Founder)Duane Valz(General Counsel)Mary Rozenman(Chief Financial Officer)

BoardVijay Pande(Director)

Board seatRobert Nelsen· per SEC Form D

Juno TherapeuticsJun 2015

BiotechSeattle, US

Howard Pien(Director)Hal Barron(Director)Hans Bishop(Executive Officer, Director, Promoter)Bernard J. Cassidy(Executive Officer)Rupert Vessey(Director)Robert Azelby(Executive Officer)

Board seatRobert Nelsen· per SEC Form D

LyceraJun 2015SEC filingmedium confidence

BiotechAnn Arbor, US

Michael Hayden(Director)Michael Steinmetz(Director)Steven Gillis(Director)Paul Sekhri(Executive Officer)Timothy Mayleben(Director)

BoardRobert Kamen(Director)

Board seatKristina BurowSteven Gillis· per SEC Form D · filed Jun 2015

Medical Creationsxtremity.cominJun 2021SEC filingmedium confidence

Xtremity develops thermoformable carbon-reinforced polymer prosthetic socket technology and cost-efficient fabrication processes for individuals with transtibial limb loss and the prosthetists who treat them.

HardwareHealthtechMedical DevicesAspen, US

Miguelangel Sosa(Executive Officer, Director)Amy Hill(Executive Officer)Scott Ward(Executive Officer)Mark Joseph(Founder / Inventor & Product Designer)

Board seatRobert Nelsen· per SEC Form D · $15M raise · filed Jun 2021

Metacrinemetacrine.comJan 2015SEC filingmedium confidence

BiotechSan Diego, US

Trisha Millican(Executive Officer)Ken Song(Executive Officer, Director)Ronald Evans(Director)

BoardAmir Nashat(Director)

Board seatKristina BurowRichard Heyman· per SEC Form D · $37.8M raise · filed Nov 2016

Metserametsera.comin𝕏Nov 2024

Pfizer is a pharmaceutical company that develops medicines for treating various diseases, with a focus on enriching and extending life through innovation in drug development and patient assistance programs.

HealthtechMedical Devices

Board seatKristina BurowPaul Berns· per SEC Form D

Mirador Therapeuticsmiradortx.cominApr 2024

Mirador discovers and develops precision medicines for immune-mediated and immuno-fibrotic diseases using a target-patient matching approach.

AI & Machine LearningHealthtechMedical DevicesSan Diego, US

Joseph Papa(Director)Mark C. McKenna(Executive Officer, Director)Scott Glenn(Director)Vika Brough(Executive Officer)Timothy K. Andrews(Executive Officer)

Board seatKristina BurowPaul Berns· per SEC Form D

Nanosysnanosys.cominFeb 2015SEC filingmedium confidence

Nanosys develops Quantum Dot technology and materials, providing samples, R&D collaboration, and scaled production for partners building display and other advanced-material products.

Advanced ManufacturingDeep TechHardwareNew MaterialsSemiconductorsMilpitas, US

Bruce Berkoff(Director)Greg Yurek(Director)John Young(Director)Regis McKenna(Director)Steven Goldby(Director)Stephen Oesterle, M.D.(Director)

Board seatKeith Crandell· per SEC Form D · $10M raise · filed Mar 2015

National Resilience, Inc.Jan 2021SEC filingmedium confidence

La Jolla, US

Board seatRobert Nelsen· per SEC Form D · $755M raise · filed Jan 2021

Nutcracker Therapeuticsnutcrackerx.comSep 2021

BiotechEmeryville, US

Igor Khandros(Executive Officer, Director)

Board seatRobert Nelsen· per SEC Form D

Octave Bioscience IncMar 2025SEC filingmedium confidence

HealthtechMenlo Park, US

William Hagstrom(Executive Officer, Director)Melinda Thomas(Executive Officer)Mark Weeks(Executive Officer)Thomas Hawes(Director)A. Grant Heidrich III(Director)Andrea Jackson(Director)

Board seatGeorge Scangos· per SEC Form D · $53.7M raise · filed Mar 2025

Ollin Biosciences, Inc.Jun 2026SEC filingmedium confidence

A clinical-stage biotechnology company focused on therapies for vision-threatening conditions including wet AMD and diabetic macular edema.

Austin, US

Board seatPaul Berns· per SEC Form D · $330M raise · filed Jun 2026

OncoResponseoncoresponseinc.comMar 2021SEC filingmedium confidence

BiotechHouston, US

Alice Bexon(Executive Officer)Clifford J. Stocks(Director, Executive Officer)Kamal D. Puri(Executive Officer)Chris Russell(Executive Officer)Russ Hawkinson(Executive Officer)Alan Ginsberg(Director)

Board seatSteven Gillis· per SEC Form D · $60M raise · filed Mar 2021

Pheast Therapeuticspheast.comin𝕏Oct 2025

Pheast Therapeutics develops immunotherapies targeting cancer, building on foundational research from Stanford's stem cell research institute.

BiotechHealthtechMedical DevicesRedwood City, US

Irv Weissman(Cofounder, Scientific Advisor, Board Director)Ravi Majeti(Cofounder, Scientific Advisor, Board Observer)Amira Barkal(Principal Founder, Scientific Advisor, Board Director)Roy Maute(Cofounder & Chief Executive Officer)

BoardJacob Vogelstein(Director)

Board seatSteven Gillis· per SEC Form D

PronirasJan 2025SEC filingmedium confidence

BiotechSeattle, US

CHRISTOPHER TOOMBS(Executive Officer)LINDSAY RAYLE(Executive Officer, Promoter)Asish Xavier(Director)M. Johnston Erwin(Director)David Schubert(Executive Officer, Promoter)Joel Marcus(Director)

Board seatSteven Gillis· per SEC Form D · $12.2M raise · filed Jan 2025

Ramona Optics, Inc.ramonaoptics.cominMar 2026SEC filingmedium confidence

BiotechDurham, US

Roarke Horstmeyer(Director)Gregor Horstmeyer(Executive Officer, Director)Mark Harfouche(Executive Officer, Director)Margaret Aery(Executive Officer)Robert Horstmeyer(Director)

Board seatSean KendallPatrick Weiss· per SEC Form D · $31M raise · filed Mar 2026

Rezo Therapeuticsrezotx.comAug 2025SEC filingmedium confidence

Rezo Therapeutics is a drug discovery and development company focused on oncology and inflammation therapeutic areas.

AI & Machine LearningBiotechDeep TechSan Francisco, US

Nevan Krogan(Co-Founder)Sourav Bandyopadhyay(Co-Founder)Norbert Bischofberger(Co-Founder)Natalia Jura(Co-Founder)George Scangos(Co-Founder)Kevan Shokat(Co-Founder)

Board seatGeorge Scangos· per SEC Form D · $80.1M raise · filed Aug 2025

RIPPL Careripplcare.comin𝕏Oct 2024

Rippl delivers evidence-based dementia care through a combination of technology and human support for people living with dementia and their families.

Digital HealthHealthtechSeattle, US

Kris Engskov(Co-founder & CEO)Robert Nelsen(Co-Founder & Board Chair)Paul Engskov(Executive Officer, Director)

BoardHolly Maloney(Director)Iyah Romm(Director)Ryan Watts(Director)

Board seatRobert Nelsen· per SEC Form D

Sana Biotechnologysana.cominOct 2018

Sana is a biotech company developing engineered cell medicines, including gene therapies for gene modification and delivery, cell replacement therapies using stem cell biology, and manufacturing solutions to improve patient access to these treatments.

BiotechHealthtechMedical DevicesSeattle, US

Steve Harr(President and Chief Executive Officer)

Board seatRobert Nelsen· per SEC Form D

Sapphire EnergyDec 2015SEC filingmedium confidence

EnergySan Diego, US

James E. Levine(Chief Executive Officer and President)Steven Goldby(Director)Eric Luo(Director)James Astwood(Senior Vice President of Product Management)James Butler(Vice President of Legal Affairs and Intellectual Property)Wang Cheng(Director)

Board seatRobert Nelsen· per SEC Form D · $92M raise · filed Dec 2015

SempriusDec 2014SEC filingmedium confidence

Durham, US

GREG WOLF(Director)JOHN ROGERS(Executive Officer, Director)JOSEPH CARR(Executive Officer, Director)JOHN GLUSHIK(Director)HELENA YEE(Executive Officer)JOHN REGAN(Director)

Board seatClinton Bybee· per SEC Form D · $1.7M raise · filed Jan 2015

Seranova Bioseranovabio.cominFeb 2024SEC filingmedium confidence

BiotechNew Haven, US

Beatrice McQueen(Executive Officer)Aaron Ring(Manager)Jim Tananbaum(Manager)

Board seatSabah Oney· per SEC Form D · $10M raise · filed Feb 2024

Sienna BiopharmaceuticalsApr 2017SEC filingmedium confidence

BiotechWeslake Village, US

Dennis Fenton(Director)Bob More(Director)Diane Stroehmann(Executive Officer)Frederick C. Beddingfield III(Executive Officer, Director)Paul F. Lizzul(Executive Officer)Ric Peterson(Executive Officer)

Board seatRobert NelsenKristina Burow· per SEC Form D · $40.5M raise · filed May 2017

Siluria TechnologiesJul 2014SEC filingmedium confidence

San Francisco, US

Michel Maloof(Director)Leighton Read(Director)Edward J Dineen(Executive Officer, Director)Paula Reynolds(Director)Jeffrey P. Wood(Executive Officer)Mark Noetzel(Director)

Board seatClinton Bybee· per SEC Form D · $25.7M raise · filed Jan 2016

Skylark Bioskylarkbio.comAug 2022

BiotechCambridge, US

Giampiero De Luca(Director)Jodi A. Cook(Executive Officer, Director)Will McLean(Executive Officer)

Board seatSteve Gillis· per SEC Form D

Slingshot Biosciencesslingshot.bioApr 2024

Emeryville, US

Adam Wieschhaus(Director)Jeffrey Kim(Executive Officer, Director)Ronald J. Silberman(Director)

Board seatCorey RitterPatrick Weiss· per SEC Form D

SonoTherasonothera.comin𝕏Jun 2026SEC filingmedium confidence

SonoThera develops a nonviral, ultrasound-mediated gene delivery technology to safely deliver genetic material to targeted sites in the body.

BiotechDeep TechMedical DevicesSouth San Francisco, US

Board seatSteven Gillis· per SEC Form D · $125.5M raise · filed Jun 2026

Syros Pharmaceuticals, Inc.Jan 2018SEC filingmedium confidence

Cambridge, US

Board seatRobert NelsenVicki Sato· per SEC Form D · $11.4M raise · filed Feb 2018

Treeline Biosciencestreeline.bioSep 2025

Treeline develops therapeutics focused on oncology, leveraging insights from clinical practice and laboratory research.

AI & Machine LearningBiotechMedical DevicesWatertown, US

Joshua H. Bilenker(Executive Officer, Director, Promoter)Jeffrey Engelman(Executive Officer, Director, Promoter)

BoardAli Satvat(Director)David Schenkein(Director)Steven Elms(Director)

Board seatKristina Burow· per SEC Form D

TrelysMar 2017SEC filingmedium confidence

BiotechHayward, US

Jay Kouba(Executive Officer, Director)Thomas Erickson(Director)Doug Cameron(Director)

Board seatKristina Burow· per SEC Form D · $80K raise · filed Apr 2017

Ultivueultivue.comin𝕏Jul 2024

Vizgen provides spatial multiomics platforms that enable researchers, clinicians, and biopharma teams to map and analyze RNA and protein molecules at single-cell resolution for disease understanding and precision medicine applications.

AI & Machine LearningBiotechMedical DevicesCambridge, US

Peng Yin(Director)Fenel Eloi(Director)Robert Carson(Executive Officer, Director)Peng Ying(Executive Officer, Director)David R. Walt(Executive Officer, Director)

BoardAndrea Jackson(Director)

Board seatKeith Crandell· per SEC Form D

Unity Biotechnologyunitybiotechnology.comOct 2016

Brisbane, US

Board seatRobert NelsenKristina Burow· per SEC Form D

Vividion Therapeuticsvividion.cominApr 2019acquired by Bayer

Vividion Therapeutics develops small molecule therapeutics using a covalent-first chemoproteomics approach to identify and target previously undruggable proteins.

AI & Machine LearningBiotechDeep TechPrinceton, US

Ben Cravatt(Scientific Founder)Phil Baran(Scientific Founder)Jin-Quan Yu(Scientific Founder)

BoardJohn Park(Executive Officer)John Clarke(Executive Officer, Director)

Board seatKristina BurowRichard Heyman· per SEC Form D

Voxel8voxel8.comJul 2015

Company producing world's first multi-material 3D printer capable of printing functional features with variable material properties.

Somerville, US

Jennifer A. Lewis(Executive Officer, Director)

BoardJiong Ma(Director)

Board seatClinton Bybee· per SEC Form D

Xtera CommunicationsAug 2015SEC filingmedium confidence

Allen, US

Keith Henderson(Executive Officer)Kevin Martin(Director)Barry Fromberg(Director)John McLaren(Director)Cliff Higgerson(Director)Les Barkley(Executive Officer)

Board seatClinton Bybee· per SEC Form D · $1.5M raise · filed Sep 2016

Accompany Healthaccompanyhealth.comMar 2023

HealthtechBethesda, US

Stephanie Lovell(Director)Rahul Rajkumar(Executive Officer, Director)Bryan Roberts(Director)Vivian Riefberg(Director)Robert Kocher(Director)

Akamis Bioakamisbio.comin𝕏

Akamis Bio develops oncolytic immunotherapies for colorectal cancer treatment, aiming to offer alternatives to surgery that preserve patient function and quality of life.

BiotechDigital HealthHealthtechMedical Devices

Aledadealedade.comin𝕏

Aledade is an accountable care organization (ACO) partner that works with primary care organizations to improve patient outcomes and healthcare quality.

Enterprise SoftwareHealthtechBethesda, US

Bijan Salehizadeh(Co-founder)Robert Kocher(Director)Farzad Mostashari(Executive Officer, Director)

Alnylamalnylam.comin𝕏

Alnylam is a biopharmaceutical company that supports investigator-initiated studies in therapeutic areas including transthyretin-mediated amyloidosis, acute hepatic porphyria, and primary hyperoxaluria for medical researchers and healthcare professionals.

BiotechDigital HealthMedical Devices

Altos Labsaltoslabs.comin𝕏

Altos Labs develops computational and scientific approaches to reverse disease through breakthrough medicines, operating research institutes focused on cell health, computation, and drug discovery.

BiotechDeep TechLongevityBay Area, US

Richard Murray(CEO and Founder)Shinya Yamanaka(Chief Scientific Advisor and Founder)

Arraybiopharmaarraybiopharma.com
Arsenal Biosciencesarsenalbio.com

Arsenal Biosciences is a clinical-stage company developing programmable cell therapies to treat solid tumors.

BiotechHealthtechMedical DevicesSouth San Francisco, US

James Ahlers(Executive Officer)Kenneth Drazan(Executive Officer, Director)Irene Pleasure(Executive Officer)Margaret Nibbi(Executive Officer)

BoardValentin Barsan(Director)Sean Parker(Director)

Bit Biobit.bioin𝕏

bit.bio is a synthetic biology company that engineers human induced pluripotent stem cells into defined cell types for research, drug discovery, and cell therapy applications.

BiotechDeep TechHealthtechMedical Devices

Dr Mark Kotter(Founder)Przemek Obloj(CEO)

Bitterroot Bio
Bluebird Biobluebirdbio.comin𝕏Sep 2021

Genetix Biotherapeutics (formerly bluebird bio) develops gene therapies for patients with rare genetic diseases including sickle cell disease, beta-thalassemia, and cerebral adrenoleukodystrophy.

BiotechLongevityMedical DevicesCambridge, US

David Meek(Chief Executive Officer)Brian Riley(President & Chief Technical Officer)Joanne Lager(Chief Medical Officer)Wendy DiCicco(Chief Financial Officer)Adrian Chaisson(Chief of Staff)Daniel S. Lynch(Director)

Brii Biosciencesbriibio.com
Carrick Therapeuticscarricktherapeutics.comin

Carrick Therapeutics is a biopharmaceutical company with a leadership team experienced in oncology drug development and commercialization.

BiotechDigital HealthHealthtechMedical Devices

Timothy Pearson(CEO)Ash Bahl(CSO)Jenny Horsfield(CBO)Stuart McIntosh(CMO)David Sutherland(VP Finance & Controller)

City Therapeuticscitytx.comin𝕏

City Therapeutics develops RNAi-based medicines targeting rare, specialty, and prevalent diseases using engineered trigger molecules and precision delivery ligands.

BiotechMedical DevicesCambridge, US

Mark Keating, MD(Co-founder)Kotaro Nakanishi, PhD(Co-founder)Yukihide Tomari, PhD(Co-founder)Phillip Zamore, PhD(Co-founder)

Codiakbiocodiakbio.com
CStone Pharmaceuticalscstonepharma.com
Curie Biocurie.bio
Decodedecode.com

deCODE analyzes and interprets the human genome to identify genetic risk factors for common diseases including cardiovascular disease and cancer.

AI & Machine LearningBiotechDeep TechReykjavik, IS

Dispatch Biotherapeuticsdispatchbio.comin𝕏

Dispatch Bio develops a universal immunotherapy treatment for solid tumors, combining engineered immunotherapy with a tumor-specific virus to improve cancer treatment outcomes.

BiotechDeep TechMedical Devices

Lex Johnson(Co-Founder and Chief Platform Officer)Ray Liu(Co-founder and Head of Synthetic Biology)Sabah Oney(Chief Executive Officer)

Encoded Therapeuticsencoded.comin𝕏

Encoded develops gene therapies for neurological disorders through an integrated platform approach.

Biotech

Encodiaencodia.com
Enumerixenumerix.comin

Countable Labs (formerly Enumerix) develops a digital PCR platform that performs genetic analysis with higher sensitivity, precision, and dynamic range than legacy PCR methods.

AI & Machine LearningBiotechDeep TechMedical Devices

EQRxeqrx.com
Gate Biogatebio.com

Gate Bioscience develops small molecule therapeutics called Molecular Gates for disease treatment.

BiotechDeep TechMedical Devices

Jordi Mata-Fink(Chief Executive Officer, Co-Founder)inRaman Talwar(Chief Technology Officer, Co-Founder)inPat Sharp(Scientific Founder)in

Grailbiograilbio.comin𝕏

GRAIL develops a blood-based multi-cancer early detection test called Galleri that uses next-generation sequencing and machine learning to screen for multiple cancer types before symptoms appear.

BiotechDigital HealthHealthtechMedical DevicesMenlo Park, US

hC Biosciencehcbioscience.com

Cambridge, US

Brad Margus(Director)Leslie J Williams(Executive Officer, Director)Benjamin Chen(Director)Seiji Miyahara(Director)Sacha Mann(Director)David Moskowitz(Director)

HiberCellhibercell.comin

HiberCell develops therapeutic candidates targeting the Integrated Stress Response pathway to address treatment-resistant cancers, relapse, and metastasis.

BiotechMedical Devices

Julio Aguirre-Ghiso, Ph.D.(Co-Founder)

Homewardhomeward.comin𝕏

Homeward provides cash offers for home purchases, allowing buyers to make competitive offers without financing contingencies while enabling real estate agents to maintain full commissions.

FintechPropTechAustin, US

Jeff Diehl(Director)Jeffrey Crowe(Director)Srini Palamarthy(Executive Officer)Ben Rubenstein(Director)

BoardTim Heyl(Executive Officer, Director)Krishna Srinivasan(Director)

Homeward Healthhomewardhealth.comin

Homeward Health provides in-home and virtual primary care and care coordination services for Medicare Advantage patients, helping with appointment scheduling, health advocacy, insurance navigation, and access to community resources.

Digital HealthHealthtech

Homology Medicineshomologymedicines.com
Hua Medicinehuamedicine.com
Human Immunology Biosciences

A precision immunology company co-incubated with Arch Venture Partners leveraging human genetics for autoimmune disorder treatments (exited May 2024).

IDbyDNAillumina.com
Inograft Biotherapeutics

Organ and stem cell transplant immune suppression therapies

IntegenX

Thermo Fisher Scientific operates a commercial platform for registered customers, distributors, and authorized representatives to purchase products and services in the life sciences sector.

BiotechEnterprise SoftwareHealthtech

Jaguar Gene Therapyjaguargenetherapy.comin

Jaguar Gene Therapy develops gene therapy treatments for severe genetic diseases, focusing on AAV-based platform therapies designed to deliver one-time, long-lasting treatments.

BiotechHealthtechMedical Devices

Junotherapeuticsjunotherapeutics.com
JUST Biotherapeuticsjustbiotherapeutics.comin

Just - Evotec Biologics is a CDMO providing development and cGMP manufacturing services for antibodies, next-generation biologics, and biosimilars.

BiotechDeep TechMedical DevicesSeattle, US

JW Therapeuticsjwtherapeutics.com

A biopharmaceutical company developing CAR-T cell therapies for cancer treatment.

BiotechHealthtechMedical DevicesShanghai, CN

Karunatxkarunatx.com
Kisbeetxkisbeetx.com
KSQ Therapeuticsksqtx.comin𝕏Sep 2018

KSQ Therapeutics develops eTIL therapies—engineered tumor-infiltrating lymphocyte treatments for solid tumors—using its proprietary CRISPRomics platform to identify and target novel therapeutic candidates through genome-wide CRISPR/Cas9 functional genomic screens.

AI & Machine LearningBiotechMedical DevicesCambridge, US

GEORGE GOLUMBESKI(Director)RICHARD A. MOSCICKI, PH.D.(Director)ALAN L. CRANE(Director)JAMES GILBERT(Director)JOHN TRZUPEK, PH.D.(TREASURER, SECRETARY & CHIEF FINANCIAL OFFICER)DAVID P. MEEKER, M.D.(PRESIDENT AND CHIEF EXECUTIVE OFFICER)

LifeMine Therapeuticslifeminetx.cominSep 2016

LifeMine is a biopharmaceutical company that uses data science and advanced methods to accelerate drug discovery and develop precision medicines across therapeutic areas.

AI & Machine LearningBiotechDeep TechCambridge, US

Gregory L. Verdine(Executive Officer, Director)Hingge Hsu(Executive Officer, Director)Weiqing Zhou(Executive Officer, Director)

Lightcastlightcast.bioin

Lightcast develops Envisia, a next-generation platform for single-cell functional screening and analysis that enables researchers to study biomolecule secretion, cell-cell interactions, and targeted cell killing at scale.

AI & Machine LearningBiotechDeep Tech

Lightcast Discoverylightcastd.comin

Lightcast provides a next-generation single-cell functional analysis platform called Envisia that enables massively parallel profiling of cell-cell interactions and biomolecule secretion at scale.

BiotechDeep TechMedical Devices

Lilac Therapeutics

Small molecule therapies to treat kidney stones

Lyellbiotechlyellbiotech.com
Matter Neurosciencematter.xyz

Matter develops a consumer iOS app that helps users track positive emotions and brain activity to improve subjective well-being.

AI & Machine LearningConsumerHealthtechMental HealthWellness & Fitness

Axel Bouchon(Founder)Ben Goldhirsh(Co-founder)Chris Shiflett(Co-founder)

Mozart Therapeuticsmozart-tx.com

Mozart Therapeutics develops protein therapeutics focused on immunology and oncology treatments.

BiotechMedical Devices

Mark Davis(Scientific Co-Founder)K. Christopher Garcia(Scientific Co-Founder)Calvin Kuo(Scientific Co-Founder)Katie Fanning(President & Chief Executive Officer)

Myeloid Therapeuticsmyeloidtx.comin𝕏

CREATE Medicines develops in vivo CAR immunotherapy using proprietary mRNA-LNP technology to program T cells, NK cells, and myeloid cells directly within the body for cancer, autoimmunity, and fibrosis.

AI & Machine LearningBiotechHealthtechMedical Devices

nChroma Bionchromabio.comin𝕏

nChroma Bio develops in vivo targeted delivery and genetic engineering technologies for genetic medicine applications.

BiotechDeep TechMedical Devices

Luke Gilbert, PhDKeith Joung, MD, PhDDavid Liu, PhDAngelo Lombardo, PhDLuigi Naldini, MD, PhDJonathan Weissman, PhD

Ocera Theraputicsin

Keenova Therapeutics is a specialty pharmaceutical company developing treatments for rare, stigmatized, or unaddressed conditions across therapeutic areas including immunology, urology, hepatology, ophthalmology, orthopedics, and critical care.

BiotechHealthtechMedical Devices

Omniomeomniome.com
OneBioMedonebiomed.com
ONIoni.bioin𝕏

ONI develops the Nanoimager, an automated super-resolution imaging system.

BiotechDeep TechHardwareMedical DevicesOxford, GB

Orbital Therapeuticsorbitaltx.comin𝕏

A pharmaceutical company developing therapeutics across oncology, hematology, neuroscience, immunology, and cardiovascular disease with a pipeline of 50 compounds targeting 40+ disease areas.

BiotechHealthtechMedical Devices

Paratus Sciencesparatussciences.comin

Paratus Sciences develops first-in-class medicines for cardiometabolic and immune & inflammatory diseases by leveraging evolutionary biology and AI to identify novel drug targets.

AI & Machine LearningBiotechDeep TechUnited States, US

Protillion Biosciencesprotillion.cominDec 2022

Protillion Biosciences develops platform technology for antibody engineering and drug discovery.

AI & Machine LearningBiotechDeep TechCarlsbad, US

Curtis Layton(CEO/Co-Founder)inDavid Walt(Co-Founder)inWill Greenleaf(Co-Founder)inRobert Hollingsworth(Chief Scientific Officer)in

BoardSean Kendall(Director)Malek Faham(Director)

Qihan Biotechqihanbio.com
Quantum Circuitsquantumcircuits.comin

Quantum Circuits develops superconducting quantum computers using dual-rail qubits with built-in error detection, designed to accelerate the path to fault-tolerant quantum computing.

Advanced ManufacturingDeep TechHardwareQuantum ComputingMadison, US

Rob Schoelkopf(Sterling Professor, Founder)Luigi FrunzioRay SmetsBrian W Pusch(Executive Officer, Director)

Qubitqubit.comin

Qubit, now part of Coveo, provides AI-powered ecommerce personalization tools including search, product recommendations, and merchandising capabilities for online retailers.

AI & Machine LearningE-commerceMarketing Tech

Reactive Biosciencesboragenbio.com
Receptosreceptos.com
Recuro Healthrecurohealth.comin𝕏Aug 2022

Recuro is a virtual-first digital health platform that provides primary care, behavioral health, urgent care, and supplemental benefits (pharmacy, care management, advocacy) to patients, employers, health plans, and providers.

Digital HealthHealthtechSaaSRichardson, US

Michael Brombach(Chief Executive Officer and Co-Founder)Dr. Kate Sowerwine(Chief Medical Officer)John Halsey(Director)Michael Moradi(Director)Michael Gorton(Chief Executive Officer)Kris Engskov(Director)

Remix Therapeuticsremixtx.comin𝕏Dec 2023

Remix Therapeutics develops RNA reprogramming technology to treat various diseases and disorders.

AI & Machine LearningBiotechWatertown, US

Peter Smith, PhD(Co-Founder, President and Chief Executive Officer)Peter Smith(Co-Founder, President and Chief Executive Officer)Robert Gagnon(Executive Officer)Matthew Patterson(Director)Scott Biller(Director)Heather Wasserman(Executive Officer)

Resilienceresilience.com

Resilience is a contract development and manufacturing organization (CDMO) that manufactures complex pharmaceutical products and active pharmaceutical ingredients to broaden access to medicines and protect biopharmaceutical supply chains against disruption.

Advanced ManufacturingBiotechEnterprise SoftwareBlue Ash, US

William S. Marth(Chief Executive Officer)

BoardRobert Nelsen

Sagerxsagerx.comin

Biopharmaceutical company developing and commercializing treatments for central nervous system (CNS) diseases.

BiotechMedical Devices

Scale Biosciencesscale.bioin𝕏

Scale Biosciences develops patented single-cell analysis technology that enables researchers to conduct massively parallelized sequencing at reduced cost.

AI & Machine LearningBiotechDeep Tech

Garry Nolan(Scientific Co-Founder)Frank Steemers(Scientific Co-Founder)Jay Shendure(Scientific Co-Founder)Cole Trapnell(Scientific Co-Founder)

SciNeuro Pharmaceuticalsscineuro.comin

SciNeuro develops targeted therapeutics for neurodegenerative and age-related brain diseases by integrating patient genetics, health history, and advanced diagnostic tools.

BiotechDeep TechDigital HealthLongevityMedical Devices

Min Li(CEO & Director)Sam Agus(CSO/CMO)Paul Stead(CBO)

Semma Therapeuticssemma-tx.com
Singleron Biotechnologiessingleronbio.comin𝕏

Singleron Biotechnologies develops single-cell and single-nucleus sequencing kits and solutions for transcriptome analysis of biological samples.

BiotechMedical DevicesCologne, DE

Singular Genomics Systemssingulargenomics.comin𝕏

Singular Genomics develops spatial pathology technology to map molecules and cells directly in tissue for disease characterization.

BiotechDeep TechMedical Devices

John Stark(CEO)Aaron Berlin(CTO)

Sironaxsironax.com

Sironax develops treatments that target underlying contributors of degeneration, including disrupted energy homeostasis, dysregulated cell death, and inflammation, across multiple organs and tissues.

BiotechHealthtechLongevity

Sonoma Biotherapeuticssonomabio.comin𝕏Jul 2021

Sonoma Biotherapeutics develops engineered regulatory T cell therapies to treat autoimmune and inflammatory diseases.

BiotechHealthtechMedical DevicesSouth San Francisco, US

Fan Yu(Director)Maggie Wilderotter(Director)Toni Hoover(Director)Terry Rosen(Director)Richard Klausner(Director)Jeffrey Bluestone(Executive Officer, Director, Promoter)

SonoTherasonotherabio.comin𝕏

SonoThera is developing a nonviral, non-invasive gene delivery technology that uses ultrasound and microbubbles (ultrasound enhancing agents) to deliver genetic payloads to targeted sites in a redosable manner.

BiotechDeep TechDigital Health

SunBird Biosunbirdbio.com
Synchronsynchron.comin𝕏Nov 2022

Synchron develops brain-computer interface technology delivered via catheter to restore or improve motor and cognitive function in people with impairment or decline.

BiotechDeep TechMedical DevicesCampbell, US

Thomas James Oxley(Executive Officer, Director)Martin Dieck(Director)Nicholas Opie(Director)Rahul Sharma(Director)

BoardAlex Morgan(Director)

Syrossyros.com
Transcenta Holdingtranscenta.com
Trasetrase.aiin

Trase builds AI systems with built-in governance and auditability for organizations in high-stakes domains such as defense, healthcare, and critical infrastructure.

AI & Machine LearningDeep TechDefense TechEnterprise Software

VBI Vaccinesvbivaccines.comin𝕏Aug 2015

BiotechCambridge, US

Marc Kirchmeier(Vice President, Formulation Development)Egidio Nascimento(Chief Financial Officer)David Anderson(Senior Vice President, Research)Trent Davis(Director)Michael Steinmetz(Director)Michel De Wilde(Director)

Verve Therapeuticsvervetx.comJan 2021

BiotechCambridge, US

Andrew Ashe(Executive Officer)Burt Adelman(Director)John Evans(Director)Sekar Kathiresan(Executive Officer, Director)Andrew Bellinger(Executive Officer)

BoardAnthony Philippakis(Director)

Vesalius Therapeuticsvesaliustx.com

Vesalius Therapeutics develops a computational platform that identifies distinct disease subtypes within common diseases like heart failure, diabetes, and Alzheimer's by analyzing patient data and gene circuits, then uses proprietary cell-based models to discover targeted drug candidates.

AI & Machine LearningBiotechDeep TechCambridge, US

Yasir Al-Wakeel(CEO)in

Vilyavilyatx.comin

Vilya designs novel macrocycles using AI and computational biology to create medicines that don't exist in nature.

AI & Machine LearningBiotechDeep Tech

David Baker(Scientific Founder)Patrick Salveson, PhD(Co-Founder, CTO)Adam Moyer, PhD(Co-Founder, VP of Molecular Design)David Baker, PhD(Nobel laureate, Co-Founder, Director, IPD UW, Prof. Biochemistry)Gaurav Bhardwaj, PhD(Co-Founder, UW, Asst. Prof. Medicinal Chemistry)Lance Stewart, PhD, MBA(Co-Founder, CSO & COO, IPD)

Virvir.bioin𝕏

Vir Biotechnology develops treatments for infectious diseases and oncology, leveraging immunology-focused scientific capabilities.

AI & Machine LearningBiotechDigital HealthMedical Devices

Marianne De Backer(CEO)

Volastravolastratx.comin𝕏

Volastra is a clinical-stage biotechnology company developing oncology therapeutics that target chromosomal instability in cancer cells.

BiotechNew York, US

David P. Southwell(Chief Executive Officer)

Walden Bioscienceswaldenbiosciences.comin

Walden Biosciences is a clinical-stage biotech company developing disease-modifying therapies that selectively target the kidney to treat the underlying drivers of kidney disease.

BiotechMedical Devices

Xaira Therapeuticsxaira.comin𝕏

Xaira develops AI and machine learning tools for drug discovery and protein design, serving pharmaceutical and biotech companies.

AI & Machine LearningBiotechMedical Devices

Dr. Ci Chu(Chief Discovery Officer)Dr. Bo Wang(Chief AI Scientist)Dr. Ian McCaffery(SVP, Translational Science and Early Clinical Development)

Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.