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Signet Healthcare Partners

Growth equity

New York · Growth–Late Stage · 13 people tracked

Also known as SIGNET HEALTHCARE MANAGEMENT LLC · Signet Healthcare Partners Accredited Partnership · Signet Healthcare Partners QP Partnership

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Investment thesis

Signet Healthcare Partners invests growth capital in commercial-stage healthcare companies that are either revenue-generating or preparing for commercial launch, concentrating primarily on the pharmaceutical and medical device sectors. The firm actively partners with management teams to support growth and build successful businesses. Over a 25-year history, it has raised funds with total capital commitments exceeding $600 million and has invested in more than 55 companies globally.

Invests inBiotechDigital HealthHealthtechMedical DevicesGlobalNew YorkUnited States

Source: firm website, verified Aug 11, 2026.

Stage
Growth–Late Stage
Check
$10M – $50M
HQ
New York, US
Leads rounds
Leads
Instruments
Equity
Founded
1998
AUM
$600M
VC funds
7
Tracked investments
59

Team · 13 people

from the firm's website & public directories

What they invest in

from 37 of 59 portfolio companies

Biotech ×25Healthtech ×17Medical Devices ×16Deep Tech ×4Advanced Manufacturing ×3AI & Machine Learning ×2Digital Health ×2Circular Economy ×1

HQs:United States×19Canada×2Switzerland×1Denmark×1United Kingdom×1Mexico×1

Investments · 59 tracked

founders shown can be your intro path

By year:2025 · 12023 · 12022 · 12021 · 22020 · 22016 · 12015 · 210 dated

TELA Bioin𝕏NASDAQ: TELA

BiotechMalvern, US

Vince Burgass(Director)Kevin Rakin(Director)Ashley Freidman(Director)Francis Conway(Executive Officer)Maarten Persenaire(Executive Officer)Antony Koblish(Executive Officer, Director)

Ascendiapharmaascendiapharma.cominJun 2025

Ascendia Pharmaceutical Solutions is a contract development and manufacturing organization (CDMO) that provides formulation, nanotechnology, and manufacturing services for pharmaceutical and biological companies from pre-formulation through commercialization.

Advanced ManufacturingBiotechHealthtechMedical DevicesNorth Brunswick, US

Jingjun Huang(Executive Officer, Director)

BoardRobert Bloder(Director)Michael Bogda(Director)Shoufeng Li(Director)Theron Odlaug(Director)

Board seatJames Gale· per SEC Form D

Cerium Pharmaceuticalsceriumpharma.comJul 2021SEC filingmedium confidence

Cerium Pharmaceuticals is a clinical-stage biopharmaceutical company developing therapies for rare kidney diseases, with a lead program (SNP-ACTH (1-39) Gel) targeting Primary Membranous Nephropathy (PMN).

BiotechHealthtechGaithersburg, US

Gregg Lapointe(Executive Officer, Director)Gregg A. Lapointe(Executive Officer, Director)Peter Collum(Director)Steve Eskenazi(Director)Robert Rubin(Director)Tom DePasquale(Director)

Board seatJames Gale· per SEC Form D · $10.1M raise · filed Jul 2021

Gynesonicsgynesonics.comin𝕏Dec 2021SEC filingmedium confidence

Hologic develops medical technologies for women's health that detect, diagnose and treat health conditions across multiple countries.

FemTechHealthtechMedical DevicesRedwood City, US

Ken Haas(Director)Karen Talmadge(Director)Doug Fisher(Director)Christopher Owens(Executive Officer, Director)Chandra P. Leo(Director)

BoardJonathan MacQuitty(Director)

Board seatJoyce Erony· per SEC Form D · $50M raise · filed Dec 2021

Icon BioscienceNov 2015

BiotechSunnyvale, US

David Tierney(Executive Officer, Director)Song Toja(Director)William White(Director)Michael Hemric(Director)

Board seatJoyce Erony· per SEC Form D

Impulse DynamicsDec 2020SEC filingmedium confidence

BiotechDublin 2

Jason Spees(Executive Officer, Director)Shlomi Nachman(Director)Paul Bae(Executive Officer)Konstantin Poukalov(Director)Robert Faulkner(Director)Shlomo Ben-Haim(Director)

Board seatJoyce Erony· per SEC Form D · $60M raise · filed Jan 2021

Neuros Medicalneurosmedical.comOct 2020SEC filingmedium confidence

Neuros Medical develops the Altius Direct Electrical Nerve Stimulation System, an FDA-approved implantable device for managing chronic phantom limb pain and residual limb pain in adults with lower limb loss.

BiotechHealthtechMedical DevicesAliso Viejo, US

David Veino(President, Chief Executive Officer, and Secretary)Zach Stassen(Chief Financial Officer)Claiborne R. Rankin(Director)Robert J. Centa(Chief Financial Officer)Joseph J. Jankowski(Director)Scott F. Drees(Director)

Board seatJoyce Erony· per SEC Form D · $42.8M raise · filed Nov 2020

Pharmaceutics InternationalJul 2022SEC filingmedium confidence

BiotechHunt Valley, US

Syed E Abidi, Ph.D.(Director)John Fowler(Executive Officer, Director)Syed E. Abidi(Executive Officer, Director)Sana I. Abidi(Director)Julien Hecht(Executive Officer)Shahid Raza(Director)

Board seatJames Gale· per SEC Form D · $4.2M raise · filed Mar 2024

Advanticehealthadvanticehealth.com
Alpexalpex.com
Altasciencesaltasciences.comin

Altasciences is a contract research organization providing biopharmaceutical companies with preclinical safety testing, clinical pharmacology trials, bioanalysis, and manufacturing and analytical services to accelerate early phase drug development.

BiotechHealthtechMedical Devices

Amarinamarincorp.comin𝕏

Amarin Corporation is a cardiovascular health pharmaceutical company developing treatments to prevent cardiovascular disease.

BiotechHealthtechMedical Devices

Amriglobalamriglobal.comin

Curia is a CDMO (Contract Development and Manufacturing Organization) providing drug discovery, development, and manufacturing services across small molecules, generic APIs, sterile drug products, and biologics for biopharma companies.

BiotechEnterprise Software

Anteisanteis.com

Merz Aesthetics, Anteis SA develops and manufactures biomedical products for aesthetic medicine, including injectable fillers, resorbable implants, and skin hydration gels.

Medical DevicesPlan-les-Ouates, CH

ApicoreSep 2016

BiotechSomerset, US

Albert Friesen(Executive Officer, Director)Vithal Dahduk(Director)Timothy B. Sawyer(Director)Ravishanker Kovi(Executive Officer, Director)Theron E. Odlaug(Director)Todd Sone(Director)

Arborpharmaarborpharma.comin

Azurity Pharmaceuticals develops and commercializes pharmaceutical medicines across multiple therapeutic areas for patients globally.

BiotechDigital HealthHealthtechWoburn, US

Argostherapeuticsargostherapeutics.com
Avantiumavantium.comin

Avantium develops innovative plant-based materials designed to replace fossil fuel-derived chemicals and advance the transition to a circular economy.

Circular EconomyCleantechNew MaterialsNetherlands, NL

Biojectbioject.com
BionpharmaDec 2015

BiotechPrinceton, US

Gaurav Mehrotra(Executive Officer)Carol S. Ben-Maimon(Director)Richard Van Duyne(Director)David W. Goodman(Director)Venkatachalam Krishnan(Executive Officer, Director)Lavesh Samtani(Executive Officer)

Cangenecangene.comin𝕏

Emergent is a public health company that develops and manufactures medical countermeasures and protective solutions for endemic public health threats, national security preparedness, and supports biopharma innovators and organizations with manufacturing.

BiotechMedical Devices

Chr Olesenchr-olesen.dkin

Chr.

Advanced ManufacturingFoodTechLogistics & Supply ChainDenmark, DK

Clarislifesciencesclarislifesciences.com
Corerx

BiotechClearwater, US

RONALD L MILLER(Director, Promoter)MARK J LICARDE(Executive Officer, Director, Promoter)BRIAN MCMILLAN(Executive Officer, Director, Promoter)TODD R DAVIAU(Executive Officer, Director, Promoter)

Curidacurida.noin

Curida is a contract development and manufacturing organization (CDMO) that develops and manufactures liquid medicines using Blow-Fill-Seal and Nasal Spray technologies for nasal and ophthalmic applications.

Medical DevicesNorway, NO

Direvodirevo.com
Elanelan.comin𝕏

Perrigo manufactures and distributes self-care health and wellness products for consumers to treat self-managed conditions.

ConsumerHealthtechWellness & FitnessPerrigo, Michigan (implied by company name, though not explicitly stated on this page), US

Endoendo.comin

Keenova is a specialty therapeutics company focused on rare, stigmatized, or unaddressed conditions across areas including immunology, urology, hepatology, ophthalmology, orthopedics, and critical care.

BiotechHealthtechMedical DevicesMalvern, US

Scott Hirsch(Director)Paul Efron(Director)Paul Herendeen(Director)Marc Yoskowitz(Director)Patrick Barry(Executive Officer)Blaise Coleman(President; Chief Executive Officer)

Epix Therapeuticsin

Medtronic designs and develops medical technology for treating complex diseases.

AI & Machine LearningDigital HealthHealthtechMedical Devices

Ertert.comin𝕏

Clario provides endpoint technologies and software for clinical trial management, serving pharmaceutical and biotech sponsors, CROs, and clinical trial sites globally.

AI & Machine LearningHealthtechMedical Devices

Fluxionfluxionbio.comin

Cell Microsystems develops laboratory instruments and platforms for cell engineering, culture, and analysis.

BiotechDeep TechHardware

Gbibiogbibio.comin

GBI is a contract development and manufacturing organization (CDMO) specializing in biopharmaceutical manufacturing for therapeutic antibodies, recombinant proteins, and complex biologics.

BiotechDeep TechHealthtechFlorida, US

Gi Supplygi-supply.com𝕏

Laborie manufactures medical devices and diagnostic equipment for gastroenterology procedures.

HealthtechMedical Devices

Impopharmaimpopharma.com
Junopharmjunopharm.ca

BiotechMontreal, CA

Kewinckewinc.com
Laxailaxai.com
Leadingpharmaleadingpharma.com
Leon Nanodrugsleon-nanodrugs.comin

LEON develops precision nanoparticle manufacturing systems powered by patented FR-JET® mixing technology, serving pharmaceutical and biotech companies transitioning from research and development to GMP production.

BiotechDeep TechMedical Devices

Ligandligand.com
Molecularmedmolecularmed.com
NorthX Biologics
Nxbionxbio.com
Ocera Theraputicsin

Keenova Therapeutics is a specialty pharmaceutical company developing treatments for rare, stigmatized, or unaddressed conditions across therapeutic areas including immunology, urology, hepatology, ophthalmology, orthopedics, and critical care.

BiotechHealthtechMedical Devices

Octoplusoctoplus.nl
Optiscan Biomedicaloptiscancorp.comin

Dowds is a UK-based engineering company providing integrated technical solutions and design-led project delivery for complex built environments, with particular expertise in healthcare infrastructure, mechanical, electrical, and building systems integration.

Construction TechHealthtechUK, GB

PainTEQpainteq.comin
Paragonix Technologiesparagonixtechnologies.comin𝕏Mar 2023

Paragonix Technologies provides organ preservation and transport technology with controlled temperature systems and digital tracking for donor organs, serving transplant centers and procurement teams.

HealthtechMedical DevicesCambridge, US

DeWitt Davenport(Director)John Cammett(Director)Carl Rickenbaugh(Director)Alexander Arrow(Director)John McDermott(Director)Lisa Anderson(Executive Officer, Director)

Pfenexpfenex.comin

Pfenex provides a Pseudomonas fluorescens-based microbial expression platform for manufacturing recombinant proteins, antibodies, and biologics at scale.

Advanced ManufacturingBiotechDeep Tech

Pharm Intpharm-int.comin

Pii is a contract development and manufacturing organization (CDMO) that provides custom drug product manufacturing services, including aseptic injectables, oral dosage forms, and lyophilization.

BiotechHunt Valley, US

Pharmanobispharmanobis.com
RK Pharma

Complex sterile injectables CDMO

Rkpharmaincrkpharmainc.com

RK Pharma Inc develops and manufactures affordable generic pharmaceutical products, including injectables, sterile ophthalmic, dermal, and oral dosage forms.

BiotechHealthtechNew Jersey, US

Sanciliosancilio.comin𝕏

Sancilio & Company provides guidance and regulatory support to early-stage biopharmaceutical entrepreneurs on compliance, manufacturing, and funding strategy.

Biotech

Smartmedsyssmartmedsys.com

SMART Medical Systems develops the G-EYE® balloon colonoscope, a medical device for gastroenterology that assists physicians in polyp detection and removal during endoscopy procedures.

Medical Devices

Spepharmspepharm.com
Teambestteambest.comin
Teligentteligent.com
Vigenebiovigenebio.com

Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.

Exits · 1

IPOs and acquisitions across the tracked portfolio

TELA BioNASDAQ: TELA

Portfolio news

latest coverage across their companies

Frequently asked questions

What stage does Signet Healthcare Partners invest at?
Signet Healthcare Partners invests at the Growth, Late Stage stages.
What is Signet Healthcare Partners's typical check size?
Signet Healthcare Partners typically writes checks of $10M – $50M.
What sectors does Signet Healthcare Partners focus on?
Signet Healthcare Partners focuses on Biotech, Digital Health, Healthtech, Medical Devices.
Where is Signet Healthcare Partners located?
Signet Healthcare Partners is headquartered in New York, US.
Does Signet Healthcare Partners lead rounds?
Yes, Signet Healthcare Partners leads investment rounds.

Co-investors · 5

US Venture Partners

US Venture Partners (USVP) is an early-stage venture capital firm investing in information technology and healthcare companies, with four decades of investing experience.

Both backed · 1
$500K – $10M
OrbiMed

OrbiMed is a global healthcare-focused investment firm providing financing and operational support to companies across biopharmaceuticals, medical devices, digital health, diagnostics, and healthcare services.

Both backed · 1
$1M – $75M
APERTURE Venture Partners

Aperture Venture Partners is a healthcare-focused investment firm that backs entrepreneurs building companies in medical devices, pharmaceuticals, healthcare IT/services, and diagnostics.

Both backed · 1
$1M – $5M
EQT Life Sciences

EQT Life Sciences, formerly LSP, is one of Europe's largest and most experienced life sciences investors, backing companies developing therapeutics, medical devices, diagnostics and healthtech globally. It is part of EQT Group.

$11M – $66M
OUP (Osage University Partners)

OUP (Osage University Partners) is a venture capital firm that backs science-driven startups commercializing deep technology innovations emerging from university and breakthrough research.

$1M – $20M

Firms observed investing alongside Signet Healthcare Partners, from public investor directories. Shared companies are the overlap with Signet Healthcare Partners's recorded portfolio.

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