Signet Healthcare Partners
Growth equityNew York · Growth–Late Stage · 13 people tracked
Also known as SIGNET HEALTHCARE MANAGEMENT LLC · Signet Healthcare Partners Accredited Partnership · Signet Healthcare Partners QP Partnership
Investment thesis
Signet Healthcare Partners invests growth capital in commercial-stage healthcare companies that are either revenue-generating or preparing for commercial launch, concentrating primarily on the pharmaceutical and medical device sectors. The firm actively partners with management teams to support growth and build successful businesses. Over a 25-year history, it has raised funds with total capital commitments exceeding $600 million and has invested in more than 55 companies globally.
Source: firm website, verified Aug 25, 2026.
Team · 13 people
from the firm's website & public directories
What they invest in
from 41 of 59 portfolio companiesBiotech ×26Healthtech ×20Medical Devices ×19Advanced Manufacturing ×4Deep Tech ×4Consumer ×3Hardware ×3AI & Machine Learning ×2
HQs:United States×21Canada×2Switzerland×1Denmark×1United Kingdom×1Mexico×1
Investments · 59 tracked
founders shown can be your intro pathBy year:2025 · 22023 · 12022 · 12021 · 22020 · 22016 · 12015 · 211 dated
BiotechMalvern, US
Antony Koblish(Executive Officer, Director)Francis Conway(Executive Officer)Maarten Persenaire(Executive Officer)Christine Arasin(Executive Officer)Vince Burgess(Director)
BoardKevin Rakin(Director)
Co-investorsCheckmate Capital Group LLCEssex Woodlands Healthcare PartnersOrbiMed1315 Capital
Ascendia Pharmaceutical Solutions is a contract development and manufacturing organization (CDMO) that provides formulation, nanotechnology, and manufacturing services for pharmaceutical and biological companies from pre-formulation through commercialization.
Advanced ManufacturingBiotechHealthtechMedical DevicesNorth Brunswick, US
Jingjun Huang(Executive Officer, Director)
BoardRobert Bloder(Director)Michael Bogda(Director)inShoufeng Li(Director)Theron Odlaug(Director)
Board seatJames Gale· per SEC Form D
Cerium Pharmaceuticals develops and commercializes medicines for rare or "orphan" diseases, including kidney disease.
BiotechHealthtechGaithersburg, US
Gregg Lapointe(Co-Founder & Chief Executive Officer)Robert Rubin(Director)Robert J. Rubin(Co-Founder & Interim CMO)Nancy Klett(Co-Founder & Chief Operating Officer)Şemsi Burak Derkunt(Chief Scientific Officer)Brian Schreiber(Chief Medical Officer (2015 to 2021))
Board seatJames Gale· per SEC Form D · $10.1M raise · filed Jul 2021
FemTechHealthtechMedical DevicesRedwood City, US
Christopher Owens(Executive Officer, Director)Darrin Uecker(Executive Officer, Director)
BoardKen Haas(Director)Jonathan MacQuitty(Director)inMike Carusi(Director)inDoug Fisher(Director)
Board seatJoyce Erony· per SEC Form D · $50M raise · filed Dec 2021
Co-investorsAmzak HealthBain Capital Life SciencesEndeavour VisionFemHealth VenturesKaiser Permanente VenturesKluz Ventures+5 more
Icon Bioscience Inc.
BiotechMedical DevicesSunnyvale, US
David Tierney(Executive Officer, Director)
BoardSong Toja(Director)William White(Director)Michael Hemric(Director)
Board seatJoyce Erony· per SEC Form D
Impulse Dynamics develops implantable medical device technology for cardiac care, with a background in biomedical research and implantable cardiac electronics.
BiotechHardwareHealthtechMedical DevicesDublin 2, US
Shlomo Ben-Haim(Director)Jason Spees(Chief Executive Officer)Paul Bae(Chief Administrative Officer and General Counsel)David Prutchi(Executive Vice President, Chief Technology Officer)Richard J. Buchholz(Chief Financial Officer)Anthony Hong(Chief Science and Strategy Officer)
Board seatJoyce Erony· per SEC Form D · $60M raise · filed Jan 2021
Co-investorsAmzak HealthEssex Woodlands Healthcare Partners
Neuros Medical develops the Altius Direct Electrical Nerve Stimulation System, an FDA-approved implantable device that delivers patient-controlled electrical stimulation to treat chronic post-amputation pain in adult lower limb amputees.
BiotechHealthtechMedical DevicesAliso Viejo, US
David Veino(President and CEO)Zach Stassen(Chief Financial Officer)Robert J. Centa(Chief Financial Officer)Jon J. Snyder(Director, President, Secretary and CEO)
BoardWilliam Harrington(Director)
Board seatJoyce Erony· per SEC Form D · $42.8M raise · filed Nov 2020
Co-investorsAmzak HealthAPERTURE Venture PartnersCWRU Technology VenturesiSelect FundJobsOhio VenturesJumpstart Ventures+5 more
BiotechHunt Valley, US
Syed E. Abidi(Executive Officer, Director)John Fowler(Executive Officer, Director)Julien Hecht(Executive Officer)Jillian Dettinger(Executive Officer)Syed E Abidi, Ph.D.(Director)
BoardDavid Solomon(Director)
Board seatJames Gale· per SEC Form D
Advantice Health develops science-backed skincare products aimed at daily skin health and wellness across skin types, concerns, and ages.
ConsumerHealthtechWellness & Fitness
Co-investorsTA Associates
Altasciences is a contract research organization providing biopharmaceutical companies with preclinical safety testing, clinical pharmacology trials, bioanalysis, and manufacturing and analytical services to accelerate early phase drug development.
BiotechHealthtechMedical Devices
Co-investorsKilmer Group
Amarin Corporation is a cardiovascular health pharmaceutical company developing treatments to prevent cardiovascular disease.
BiotechHealthtechMedical Devices
Co-investorsAvoro Capital AdvisorsFountain Healthcare PartnersLongitude CapitalSofinnova Ventures
Curia is a CDMO (Contract Development and Manufacturing Organization) providing drug discovery, development, and manufacturing services across small molecules, generic APIs, sterile drug products, and biologics for biopharma companies.
BiotechEnterprise Software
BiotechSomerset, US
Albert Friesen(Executive Officer, Director)Ravishanker Kovi(Executive Officer, Director)Vithal Dhaduk(Director)
BoardTheron E. Odlaug(Director)James Gale(Executive Officer)Todd Sone(Director)
Avantium develops innovative plant-based materials designed to replace fossil fuel-derived chemicals and advance the transition to a circular economy.
Circular EconomyCleantechNew MaterialsNetherlands, NL
Co-investorsAster CapitalCapricorn Venture PartnersNV NOMPMVSofinnova Partners
An online store selling human growth hormone (HGH) injections, peptides, and related products such as Zptropin, Genotropin, Somatropin, Semaglutide, and Ozempic, marketed for bodybuilding, fat loss, and anti-aging.
ConsumerE-commerce
BiotechPrinceton, US
Gaurav Mehrotra(Executive Officer)Venkatachalam Krishnan(Executive Officer, Director)Lavesh Samtani(Executive Officer)
BoardJames Gale(Director)Carol S. Ben-Maimon(Director)Richard Van Duyne(Director)
BiotechClearwater, US
TODD R DAVIAU(Executive Officer, Director, Promoter)MARK J LICARDE(Executive Officer, Director, Promoter)BRIAN MCMILLAN(Executive Officer, Director, Promoter)
BoardRONALD L MILLER(Director, Promoter)
Keenova is a specialty therapeutics company focused on rare, stigmatized, or unaddressed conditions across areas including immunology, urology, hepatology, ophthalmology, orthopedics, and critical care.
BiotechHealthtechMedical DevicesMalvern, US
Blaise Coleman(President; Chief Executive Officer)Matthew Maletta(Executive Vice President; Chief Legal Officer; Secretary)Frank Raciti(Vice President; Controller; Chief Accounting Officer)Mark Bradley(Executive Vice President; Chief Financial Officer)Scott Hirsch(Director)Paul Efron(Director)
Medtronic designs and develops medical technology for treating complex diseases.
AI & Machine LearningDigital HealthHealthtechMedical Devices
Co-investors8VCCWRU Technology VenturesElevate VenturesMenlo VenturesOak Investment PartnersPfizer Venture Investments+5 more
BiotechDeep TechHardware
Co-investorsClaremont Creek VenturesMission Bay CapitalMission Biocapital
LEON develops precision nanoparticle manufacturing systems powered by patented FR-JET® mixing technology, serving pharmaceutical and biotech companies transitioning from research and development to GMP production.
BiotechDeep TechMedical Devices
Co-investorsLBBW Venture Capital GmbH
Following a 2025 merger of Mallinckrodt and Endo, the combined business separated into two companies: Keenova Therapeutics, which develops treatments for rare, stigmatized, or unaddressed conditions across areas such as immunology, urology, hepatology, ophthalmology, orthopedics, and critical care; and Par Health, which produces generics, sterile injectables, and active pharmaceutical ingredients backed by a U.S.-based manufacturing network.
Advanced ManufacturingBiotechHealthtechMedical Devices
Co-investorsARCH Venture PartnersCross Creek AdvisorsPfizer Venture InvestmentsSofinnova Ventures
Dowds is a UK-based engineering company providing integrated technical solutions and design-led project delivery for complex built environments, with particular expertise in healthcare infrastructure, mechanical, electrical, and building systems integration.
Construction TechHealthtechUK, GB
Co-investorsAscension VenturesBioBrit
PainTEQ develops minimally invasive implants (LINQ and TRAQ) made of treated, sterile bone for treating sacroiliac (SI) joint pain, positioned between conservative treatments and major surgery.
HealthtechMedical Devices
Co-investorsWindham Capital Partners
Paragonix Technologies develops, manufactures, and services organ preservation devices that combine cooling techniques with digital tracking and monitoring for clinicians managing donor organs during transplantation.
HardwareHealthtechMedical DevicesCambridge, US
DeWitt Davenport(Director)John Cammett(Director)Carl Rickenbaugh(Director)Alexander Arrow(Director)John McDermott(Director)Lisa Anderson(Executive Officer, Director)
Complex sterile injectables CDMO
RK Pharma Inc develops and manufactures affordable generic pharmaceutical products, including injectables, sterile ophthalmic, dermal, and oral dosage forms.
BiotechHealthtechNew Jersey, US
Sancilio & Company provides guidance and regulatory support to early-stage biopharmaceutical entrepreneurs on compliance, manufacturing, and funding strategy.
BiotechRiviera Beach, US
Frederick Sancilio(Executive Officer, Director)Daren Graham(Executive Officer)Andrew Folmer(Executive Officer)Stephen Porter(Executive Officer)
BoardDennis Langer(Director)Patrick Gray(Director)
SMART Medical Systems develops the G-EYE® balloon colonoscope, a medical device for gastroenterology that assists physicians in polyp detection and removal during endoscopy procedures.
Medical Devices
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.
Exits · 6
IPOs and acquisitions across the tracked portfolioTELA BioNASDAQ: TELAGynesonicsacq. by HologicArborpharmaacq. by Azurity PharmaceuticalsElanacq. by PerrigoFluxionacq. by Cell MicrosystemsGi Supplyacq. by Laborie
Portfolio news
latest coverage across their companiesTELA Bio · investing.com · Aug 10, 2026
PainTEQ · pulse2.com · Aug 30, 2025
Neuros Medical · finance.yahoo.com · Jul 10, 2025
Frequently asked questions
- How many investments has Signet Healthcare Partners made?
- Signet Healthcare Partners has 54 tracked investments, 5 of which have exited via acquisition or IPO, including 2 dated in the last 24 months.
- What stage does Signet Healthcare Partners invest at?
- Signet Healthcare Partners invests at the Growth, Late Stage stages.
- What is Signet Healthcare Partners's typical check size?
- Signet Healthcare Partners typically writes checks of $10M – $50M.
- What sectors does Signet Healthcare Partners focus on?
- Signet Healthcare Partners focuses on Biotech, Digital Health, Healthtech, Medical Devices.
- Where is Signet Healthcare Partners located?
- Signet Healthcare Partners is headquartered in New York, US.
- Does Signet Healthcare Partners lead rounds?
- Yes, Signet Healthcare Partners leads investment rounds.
- Who does Signet Healthcare Partners co-invest with?
- Signet Healthcare Partners most often shares deals with Pfizer Venture Investments, Sofinnova Ventures, 8VC, among 34 tracked co-investors.
Co-investors · 5
US Venture Partners (USVP) is an early-stage venture capital firm investing in information technology and healthcare companies, with four decades of investing experience.
OrbiMed is a global healthcare-focused investment firm providing financing and operational support to companies across biopharmaceuticals, medical devices, digital health, diagnostics, and healthcare services.
EQT Life Sciences, formerly LSP, is one of Europe's largest and most experienced life sciences investors, backing companies developing therapeutics, medical devices, diagnostics and healthtech globally. It is part of EQT Group.
APERTURE Venture Partners is a venture capital firm investing $1-5 million in early-stage companies focused on healthcare and healthy living sectors, with a geographic preference for the Northeast and West Coast.
OUP (Osage University Partners) is a venture firm that invests in science-driven startups commercializing deep technology innovations emerging from university and breakthrough research.
Firms observed investing alongside Signet Healthcare Partners, from public investor directories. Shared companies are the overlap with Signet Healthcare Partners's recorded portfolio.
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