Domain Associates
Venture capitalPrinceton · Seed–Growth · 11 people tracked
Also known as DOMAIN ASSOCIATES, LLC
Investment thesis
Domain Associates focuses on the biotech sector, having pioneered the first venture capital fund dedicated to biotech and managing multiple subsequent biotech-focused venture funds.
Source: firm website, verified Aug 3, 2026.
Team · 11 people
from the firm's website & public directories
What they invest in
from 12 of 13 portfolio companiesBiotech ×11Healthtech ×3Medical Devices ×2AI & Machine Learning ×1Deep Tech ×1Digital Health ×1Enterprise Software ×1
HQs:United States×12
Investments · 13 tracked
founders shown can be your intro pathBiotechLexington, US
Todd C. Brady(Executive Officer, Director)Ben Bronstein(Director)Stephen Tulipano(Executive Officer)Gary Phillips(Director)Neal Walker(Director)Jesse I. Treu(Director)
Board seatJesse Treu· per SEC Form D · $18.4M raise · filed Jan 2015
BiotechSan Diego, US
Gulsen Kama(Executive Officer)Mark Oldakowski(Executive Officer)Jonathan Dixon(Executive Officer)R. Erik Holmlin(Executive Officer, Director)Alka Chaubey(Executive Officer)David Barker(Director)
Board seatBrian Halak· per SEC Form D · $68.4M raise · filed Jan 2015
BiotechSan Diego, US
Ivy Zhang(Executive Officer)Saundra Pelletier(Executive Officer, Director)William Hall(Director)Kelly Culwell(Executive Officer)Justin J. File(Executive Officer)Alexander A. Fitzpatrick(Executive Officer)
Board seatKim Kamdar· per SEC Form D · $25M raise · filed May 2020
Aspen Neuroscience develops iPSC-derived autologous cell therapies for neurological diseases, with a lead product (ANPD001) in Phase 1/2a clinical trials for Parkinson's disease.
BiotechDeep TechDigital HealthMedical Devices<UNKNOWN>, US
Andrés Bratt-Leal(Co-Founder and Senior Vice President, Research & Development)Damien McDevitt(President and Chief Executive Officer)
BiotechSan Mateo, US
Kevin Starr(Director)Michael Kitt(Executive Officer)Arthur Pappas(Director)Anthony Ford(Executive Officer)Kathleen Sereda Glaub(Executive Officer, Director)Peter Hirth(Director)
Board seatJesse Treu· per SEC Form D · $55M raise · filed Jul 2015
BiotechDurham, US
Bernice Kuca(Executive Officer)Mathers P. Thomas(Executive Officer, Director)Jesse I. Treu(Director)Nadia Rupniak(Executive Officer)Timothy C. Gupton(Executive Officer)Richard J. Markham(Director)
Board seatJesse Treu· per SEC Form D · $37.1M raise · filed Jan 2015
BiotechBellevue, US
Louis Cannon(Director)Christopher Shen(Director)Immanuel Thangaraj(Director)Henry A. Plain, Jr.(Director)Michael Gertner(Executive Officer, Director)Brian Halak(Director)
Board seatBrian Halak· per SEC Form D · $22.4M raise · filed Sep 2015
BiotechLa Jolla, US
Preston Klassen(Executive Officer)Joseph Hagan(Executive Officer)Eckard Weber(Director)Brian H. Dovey(Director)Louis C Bock(Director)Patrick J Mahaffy(Director)
Board seatBrian DoveyEckard Weber· per SEC Form D · $90M raise · filed Sep 2015
HealthtechDuluth, US
Rebecca B. Robertson(Director)Anthony V. Lando(Executive Officer, Director)Gerard van Hamel Platerink(Director)Todd Meyer(Executive Officer)Jesse Treu(Director)Thomas D. Weldon(Director)
Board seatJesse Treu· per SEC Form D · $15M raise · filed Sep 2019
South San Francisco, US
Board seatBrian Halak· per SEC Form D · $125.5M raise · filed Jun 2026
BiotechCarlsbad, US
Eckard Weber(Director)Evgeny Zaytsev, M.D.(Director)Alain Schreiber(Director)Thomas M. Estok(Executive Officer, Director)Mauro Bove(Director)Tracy Parrott(Executive Officer)
Board seatKim KamdarEckard Weber· per SEC Form D · $1.2M raise · filed Jul 2015
ChromaCode develops a High-Definition PCR (HDPCR) multiplexing platform that enables genomic solutions for oncology and precision medicine, offering faster results and cost-effective workflows through automated interpretation and cloud-based software.
AI & Machine LearningBiotechHealthtechMedical DevicesCarlsbad, US
Aditya Rajagopal(Director)Paul Flook(Executive Officer, Director)James C. Blair(Director)Gregory J. Gosch(Executive Officer, Director)Axel Scherer(Director)Alexander G. Dickinson(Director)
Thermo Fisher Scientific operates a commercial platform for registered customers, distributors, and authorized representatives to purchase products and services in the life sciences sector.
BiotechEnterprise SoftwareHealthtech
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.
Fund performance · per public LP disclosures
as of Mar 2025| Fund | Vintage | Committed | Net IRR | TVPI | DPI |
|---|---|---|---|---|---|
| Domain Excelsior Fund, LPLPs: Empire State Development – New York Ventures | 2022 | — | — | 12.49x | 0.00x |
Source: public limited-partner disclosures (CalPERS, CalSTRS). Net IRR / TVPI / DPI as reported by the limited partner; a fund's early-year IRR is an interim estimate (J-curve).
Frequently asked questions
- What stage does Domain Associates invest at?
- Domain Associates invests at the Seed, Series A, Series B, Series C, Growth stages.
- What is Domain Associates's typical check size?
- Domain Associates typically writes checks of $200K – $15M.
- What sectors does Domain Associates focus on?
- Domain Associates focuses on Biotech.
- Where is Domain Associates located?
- Domain Associates is headquartered in Princeton, US.
Co-investors · 36
ARCH Venture Partners is a venture capital firm that backs and helps build transformational companies, with a strong focus on the life sciences and biotech sector.
OrbiMed is a global healthcare-focused investment firm providing financing and operational support to companies across biopharmaceuticals, medical devices, digital health, diagnostics, and healthcare services.
Vensana Capital is a venture capital and growth equity investment firm focused on partnering with entrepreneurs building breakthrough medical technology innovations to transform healthcare.
New Enterprise Associates (NEA) is a venture capital firm that invests in and provides long-term support to founders building new companies.
Unknown is an investment firm focused on emerging market opportunities in live entertainment, biosciences, technology startups, and real estate, with a portfolio spanning music festivals, artist platforms, creator financial services, and event infrastructure.
Kleiner Perkins is a venture capital firm that backs founders across technology and life sciences, with a portfolio of companies from early stage through growth.
Canaan is an early-stage venture capital firm backing founders with transformative ideas across technology and healthcare.
Meritech Capital Partners is a venture capital firm, founded in 1999, that invests in market-leading technology companies, having backed 200+ investments with 60+ IPOs.
Venrock is a venture capital firm investing across technology and healthcare, backing companies in fintech, developer infrastructure, life sciences, therapeutics, semiconductors, and consumer products.
Polaris Partners is a venture capital firm that partners with biotech and healthcare entrepreneurs to build transformational companies.
Wildcat Venture Partners is a venture capital firm that backs technology entrepreneurs aiming to create new market categories.
OUP (Osage University Partners) is a venture capital firm that backs science-driven startups commercializing deep technology innovations emerging from university and breakthrough research.
▶24 more co-investors
Versant VenturesForbionJohnson & Johnson Innovation – JJDCDeerfield Management CompanyAbingworthPivotal bioVenture PartnersStanford UniversityAisling CapitalFrazier Healthcare PartnersVivo CapitalSeventure PartnersNew Leaf Venture PartnersAlta PartnersRiverVest VenturePontifax Venture CapitalRiverVest Venture PartnersAmplitude Venture CapitalOkapi Venture CapitalJDRF T1D FundSante VenturesCincyTechRTW Investments L.P.Avedro, Inc.BioInnovation Capital
Firms observed investing alongside Domain Associates, from public investor directories. Shared companies are the overlap with Domain Associates's recorded portfolio.
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