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Black Opal Ventures

Venture capitalActively deploying

New York · Seed–Late Stage · 26 people tracked

Also known as BLACK OPAL VENTURES, LLC

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Investment thesis

Black Opal Ventures was founded by two MIT-trained partners who combined decades of experience in venture capital, deep technology, and healthcare. Eileen Tanghal brings over 20 years of venture experience investing in deep-tech and semiconductor startups, while Tara Bishop brings a career as a physician, executive, and healthcare investor advancing value-based care. The firm reflects their shared ambition to build a business grounded in collaboration, trust, and authenticity, applying their complementary expertise across technology and healthcare innovation.

Source: firm website, verified Sep 29, 2026.

Stage
Seed–Late Stage
HQ
New York, New York, US
Instruments
Equity
Founded
2021
Last 12 months
4 investments
AUM
$60M
VC funds
1
Tracked investments
26
Unicorns
1
IPOs
2

Team · 26 people

from the firm's website & curated & public directories
Dr. Tara Bishop· Founder & Managing Director
Dr. Tara Bishop, MD MPH· Founder & Managing Director
Eileen Tanghal, MBA· Founder & Managing Director
Justin Craib-Cox· Head of Investments
Justin Craib-Cox, CFA· Head of Investments
Carina Tyrrell· Venture Partner
Dr. Carina Tyrrell· Venture Partner
Eve Castel, CFA· Venture Partner
Franco Danesi· Venture Partner
Franco Danesi, MBA· Venture Partner
Joseph Jeong· Venture Partner
Joseph Jeong, PhD· Venture Partner
Tamra Lair, PhD· Industry Advisor

What they invest in

from 16 of 26 portfolio companies

AI & Machine Learning ×8Healthtech ×7Deep Tech ×6Digital Health ×5Enterprise Software ×5Medical Devices ×3Semiconductors ×3Biotech ×2

HQs:United States×11United Kingdom×1Italy×1

Who they back

founder profiles across 8 portfolio companies
38%
solo founders
3 of 8 mapped founding teams
25%
repeat founders
of 16 founders with career history

Founding team size:solo founder×32 founders×13 founders×14+ founders×3

Where their founders studiedfrom 16 founders with education data

Cornell ×2Massachusetts Institute of Technology ×2Politecnico di Milano ×2

What their founders studiedfrom 15 founders with field-of-study data

Computer Science ×10Engineering ×4Business & Management ×3

Where their founders worked beforefrom 16 founders with career history

AMD ×5SeaMicro ×4Riverstone Networks ×2

Investments · 26 tracked

founders shown can be your intro path

By year:2026 · 32025 · 32024 · 22023 · 22022 · 111 dated

Cerebras Systemscerebras.aiin𝕏NASDAQ: CBRS

Cerebras designs and manufactures wafer-scale AI processors and systems for data centers, enabling high-speed AI training and inference workloads.

AI & Machine LearningDeep TechHardwareSemiconductorsSunnyvale, US

Andrew Feldman(Founder)inGary Lauterbach(Founder)inMichael James(Founder)inSean Lie(Founder)inJean-Philippe Fricker(Founder)in

Co-investors2080 VenturesAlpha Wave GlobalArtisanal VenturesAurum Venture PartnersAzure Ventures GroupB Capital+44 more

Twist Biosciencetwistbioscience.comin𝕏NASDAQ: TWST

Twist Bioscience develops a silicon-based synthetic DNA manufacturing platform that produces high-quality DNA, genes, and NGS reagents for customers in medicine, agriculture, and industrial chemicals.

BiotechDeep TechSemiconductorsSouth San Francisco, US

William Charles Banyai(Executive Officer, Director, Promoter)Bill James Peck(Executive Officer, Promoter)Emily Leproust(Founder)inEmily Leproust, PhD(CEO and Co-Founder of Twist)Patrick Finn(President and Chief Operating Officer)inAdam Laponis(Chief Financial Officer)in

Co-investors+ND Capital3E Bioventures CapitalARCH Venture PartnersAsset Management CompanyATEL VenturesBay City Capital+10 more

Eridueridu.aiin𝕏Mar 2026✓ verified

Eridu develops networking infrastructure optimized for artificial intelligence workloads.

AI & Machine LearningCloud ComputingDeep TechHardwareSaratoga, US

Drew Perkins(Founder)inBrian Kinard(Executive Officer)in

BoardJagdeep Singh(Director)Dipender Saluja(Director)Wen Hsieh(Director)inChristian Gallagher(Director)

Co-investorsBosch VenturesCatapult VenturesMatter Venture PartnersOUP (Osage University Partners)Socratic PartnersTDK Ventures+12 more

AuthMindauthmind.cominApr 2025 · $19.3M

AuthMind develops an AI-powered identity security platform that identifies and prevents identity access risks across on-premises and cloud applications, targeting enterprise organizations.

AI & Machine LearningCloud ComputingCybersecurityEnterprise SoftwareBethesda, US

Shlomi Yanai(Co-Founder and CEO)inAnkur Panchbudhe(Co-Founder and CTO)inShlomo Yanay(Executive Officer, Director)Ankur Purushottam Parchbudhe(Executive Officer, Director)

BoardJacob Seid(Director)

Co-investorsBallistic VenturesCheyenne VenturesTeam Builder VenturesBlu Venture InvestorsK2 Access Fund

Chamber Cardiochambercardio.comin𝕏Feb 2026

Chamber provides care coordination software for healthcare systems operating under value-based care models, with a specific focus on improving cardiovascular outcomes through better data alignment and team coordination.

Digital HealthEnterprise SoftwareHealthtech

George Aloth(Founder)Jeffrey De Flavio(Founder)Sameer Sheth(Founder)

Co-investorsAlleyCorpAmerican Family VenturesCity LightFrist Cressey VenturesGeneral CatalystOptum Ventures+2 more

Darwinthesislabs.aiin𝕏Apr 2026 · $13.5M

Thesis is an AI research lab that automates AI research and development through autonomous experimentation.

Advanced ManufacturingAI & Machine LearningDeep TechEnterprise SoftwareRoboticsSan Francisco, US

Sergio Charles(Founder/CEO)inLuigi Charles(Founder)in

Co-investorsY CombinatorCRV (Charles River Ventures)GlobivestLink VenturesLiquid VenturesOak HC/FT+4 more

Empaticaempatica.comin𝕏Jul 2022

Empatica offers an FDA-cleared health monitoring platform combining medical wearables and digital biomarkers to collect continuous, clinical-quality health data from daily life.

AI & Machine LearningDigital HealthHealthtechMedical DevicesCambridge, US

Rosalind Picard(Founder)inMatteo Lai(Executive Officer, Director)inSimone Tognetti(Director)inLen Picard(Executive Officer, Director)inMario Scuderi(Director)

Co-investorsCDP Venture CapitalRA CapitalSanofi VenturesInnogest Capital

Healthier Capitalhealthiercapital.comDec 2024 · $35M

Healthier Capital is a venture capital firm that invests in technology-enabled healthcare companies seeking to reduce costs and improve care delivery.

Digital HealthFintechHealthtech

Amir Dan Rubin(CEO and Founding Managing Partner)in

Co-investorsModi VenturesDefine VenturesMacquarie CapitalMaverick VenturesOncology VenturesServiceNow Ventures+1 more

Hyrohyro.aiMay 2023 · $20M

Plug-and-play conversational AI platform enabling voice and chat interactions with information across digital channels.

Israel Krush(Founder)inRom Cohen(Founder)inUri Valevski(Founder)

Co-investorsDefine VenturesDorm RoomEntrepreneurs Roundtable Accelerator (ERA)Hanaco Venture CapitalHealthier CapitalK20 Fund+9 more

Isaacisaacantisismica.cominAug 2025 · $10.5M

ISAAC provides an active, non-invasive structural protection system based on a patented Active Mass Damper installed on building roofs to improve seismic safety and vibration control with real-time monitoring.

Construction TechIoTPropTech

Co-investorsAxon Partners GroupNovaCapitalAirAngelsB CapitalFlare Capital PartnersIndustry Ventures+3 more

Isaac Healthmyisaachealth.comin

Isaac Health provides virtual, interdisciplinary care for people experiencing memory and thinking changes, staffed by board-certified neurologists, geriatric specialists, neuropsychologists, speech-language pathologists, and care navigators.

Digital HealthHealthtechLongevity

Julius Bruch(Founder & CEO)inJoel Salinas(Founder)in

Co-investorsAurum Venture PartnersB Capital GroupB4 CapitalFlare Capital PartnersMeridian Street CapitalVU Venture Partners+4 more

Oathoath.voteOct 2025 · $24M

Political donor advising platform that directed over $37 million and 300,000 donations to 750+ candidates in 2024.

Brian Derrick(Founder)in

Co-investorsHigher Ground LabsMcKesson VenturesRackhouse Venture Capital

Optellumoptellum.com

Optellum builds an AI-powered platform for early lung cancer diagnosis, helping thoracic care teams and health systems discover, track, and assess the malignancy risk of lung nodule patients.

AI & Machine LearningHealthtechMedical Devices

Co-investorsIntuitive VenturesIQ CapitalMercia VenturesOutsized Ventures

Outpace Biooutpacebio.cominAug 2024

Outpace Bio develops engineered protein technologies and cell therapies to treat solid tumors, focusing on protein design and T cell engineering to improve cancer treatment efficacy and safety.

BiotechDeep TechMedical DevicesSeattle, US

Marc Lajoie(Founder)inScott Boyken(Founder)inStanley Riddell(Co-Founder and Scientific Advisor)Aaron Foster(Executive Officer)inCharity Scripture(Executive Officer)inEric Soller(Executive Officer)in

Co-investorsArtis VenturesRA CapitalAbstract VenturesATEL VenturesAtinum Investment Co. Ltd.Civilization Ventures Management, Llc+8 more

Paragraf - companyparagraf.comin𝕏Apr 2023

Paragraf develops graphene-based electronic devices, including molecular sensors (electrolyte-gated field-effect transistors) for biosensing and chemical sensing, and Hall effect sensors for current, position, and magnetic field measurement at cryogenic temperatures.

Deep TechNew MaterialsSemiconductorsCambridgeshire, GB

Simon Thomas(Chief Executive Officer of the issuer.)in

Co-investorsAmadeus Capital PartnersCambridge Angels groupEMV CapitalIn-Q-TelIQ CapitalMartlet Capital+5 more

Thesis Carethesiscare.comin

Thesis Care provides clinical support services to healthcare organizations using technology to enable high-value work at scale, helping improve patient outcomes and experience.

AI & Machine LearningDigital HealthEnterprise SoftwareHealthtech

Niren Gandra, MD(CEO, Co-Founder)Aditya Pandyaram(CPO, Co-Founder)inNiren Gandra(CEO, Co-Founder)in

Co-investorsCRV (Charles River Ventures)Oak HC/FT

TigerGraphtigergraph.comin𝕏

TigerGraph provides a graph analytics platform designed to reveal relationships and connections across data that traditional analytics tools miss, supporting deep multi-hop queries.

AI & Machine LearningData & InfrastructureEnterprise SoftwareMilpitas, US

Yu Xu(Founder)inLi Chen(Founder)Like Gao(Founder)Mingxi Wu(Founder)Ruoming Jin(Founder)

Co-investors11.2 CapitalCelesta CapitalDCVC (Data Collective)Eastlink Capital PartnersMundi VenturesQiming Venture Partners+5 more

Other

Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.

BlazeChamberConceivabeFlyteHealthGV20IntellihealthOutpaceParasailSequans

Exits · 2

2 IPOs

Cerebras SystemsNASDAQ: CBRSTwist BioscienceNASDAQ: TWST

Portfolio news

latest coverage across their companies

Frequently asked questions

How many investments has Black Opal Ventures made?
Black Opal Ventures has 26 tracked investments, 2 of which have exited, including 7 dated in the last 24 months.
What stage does Black Opal Ventures invest at?
Black Opal Ventures invests at the Seed, Series A, Series B, Series C, Late Stage stages.
What sectors does Black Opal Ventures focus on?
Black Opal Ventures focuses on Biotech, Deep Tech, Digital Health, Enterprise Software, Healthtech, Medical Devices, SaaS.
Where is Black Opal Ventures located?
Black Opal Ventures is headquartered in New York, US.
Who does Black Opal Ventures co-invest with?
Black Opal Ventures most often shares deals with In-Q-Tel, IQ Capital, Open Field Capital, among 81 tracked co-investors.

From the blog

visit blog ↗

Black Opal Ventures recently hosted its inaugural Global Growth Event featuring healthcare and deep tech startups, and released its 2025 Impact Report showing a portfolio of 27 companies focused on solving challenges in healthcare, security, and resilient infrastructure through frontier technologies. AI summary

Media · Podcasts & interviews

featuring the team

Medical Alley Starts: Ask Me Anything with Tara Bishop, Founder, Black Opal Ventures

Medical Alley · Tara Bishop

Images

Black Opal Ventures photo

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