Oxford Technology Management
Venture capitalHenley-on-Thames · Pre-Seed–Series A · 5 people tracked
Also known as Grillcastle Limited · Seed Capital Limited
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Investment thesis
Oxford Technology specialises in seed and early-stage investing in science and technology startups located in and around Oxford, structured through SEIS and EIS funds that give investors generous UK tax reliefs and downside protection. Its flagship three-year fund spreads subscriptions across roughly eight SEIS startups with follow-on EIS funding for high performers, while a knowledge-intensive EIS fund invests in five more mature portfolio companies. The team emphasises a science-driven selection process, highly selective deal flow (about 5 in 1,000 per year) and hands-on involvement with founders in the early years to shape business models and pricing. It also runs WOTAN, an angel network offering co-investment opportunities.
Source: firm website, verified Sep 27, 2026.
Team · 5 people
from the firm's website & public directoriesWhat they invest in
from 44 of 77 portfolio companiesBiotech ×20Healthtech ×20Medical Devices ×20Deep Tech ×16AI & Machine Learning ×14Hardware ×11New Materials ×6Cleantech ×5
HQs:United Kingdom×32United States×1
Who they back
founder profiles across 24 portfolio companiesFounding team size:solo founder×102 founders×103 founders×34+ founders×1
Where their founders studiedfrom 18 founders with education data
Imperial College London ×4University of Oxford ×3University of Cambridge ×2
What their founders studiedfrom 21 founders with field-of-study data
Engineering ×6Life Sciences ×5Medicine ×4Economics ×3Mathematics & Statistics ×3Physics ×3Chemistry ×2
Where their founders worked beforefrom 17 founders with career history
MANTIS DEPOSITION LIMITED ×2University of Exeter ×2
13 founders hold a PhD (of 21 with degree data)
Investments · 77 tracked
founders shown can be your intro pathBy year:2024 · 12017 · 12015 · 13 dated
Active Needle Technology develops active (vibrating) needle technology to improve ultrasound-guided needle interventional procedures.
Deep TechHardwareHealthtechMedical Devices
Ian Quirk(Founder & CEO)inMuhammad Sadiq(Founder & Senior Technical Officer)in
Co-investorsOxford Investment Opportunity Network (OION)
Combat is a clinical-stage cancer treatment company focused on developing therapies for bladder and prostate cancer.
BiotechHealthtechMedical Devices
Edward Bruce-White(CEO/Co-Founder)inAlberto Martinez Albalat(Director of R&D, Founder and Chairman)
Co-investorsNW Angel
Septest develops rapid point-of-need diagnostic tests for detecting infections and inflammation, including its multi-marker TRISEP test aimed at pre-hospital and community triage.
BiotechHealthtechMedical Devices
Oxford Cancer Analytics develops a diagnostics platform that combines reproducible proteomic measurement with AI to produce evidence-based insights supporting clinical decision-making.
AI & Machine LearningBiotechMedical DevicesOxford, GB
Andreas Halner(Founder and Head of Healthcare AI)inHeinrich Roder(Chief Technology Officer)inDaniel Szulc(Chief Product Officer)in
Co-investorsEka VenturesCross-Border Impact VenturesMeridian Health VenturesUK Innovation & Science Seed FundCivilization Ventures Management, LlcDigitalDx Ventures+1 more
Accelerated Diagnostics is developing decentralised diagnostics for human and veterinary markets, with a product launch planned for July 2026.
BiotechHealthtechMedical DevicesManchester, GB
Atelerix develops hypothermic hydrogel encapsulation technology that stabilises and preserves fresh cells, tissues, and blood at room temperature, eliminating the need for cryopreservation and cold-chain logistics.
BiotechMedical DevicesNew Materials
Steve Swioklo(Founder)in
Co-investorsCambridge Angels groupFuture Planet CapitalO2h VenturesUK Innovation & Science Seed Fund
Beyond Fence provides ISO-compliant safety solutions for industrial robotics and automation, focused on keeping human operators safe and in control while improving efficiency.
Advanced ManufacturingHardwareRoboticsOxford, GB
Luc Yao, MBA, MSc(Managing Director)
Bioarchitech develops oncolytic virus therapies and RNA-based immunotherapy candidates for cancer treatment.
AI & Machine LearningBiotechDeep TechHealthtech
Geoff Hale(Founder, Chairman)inLili Wang(Scientific Advisor & Co-founder)inHannah Chen(Scientific Advisor & Co-founder)
Covatic develops an on-device advertising platform powered by AI and machine learning that identifies user cohorts and delivers targeted ads while preserving consumer privacy.
AdTechAI & Machine LearningIoTLondon, GB
Nick Pinks(Founder)in
Co-investorsCreative UKTechstarsOxford Science EnterprisesTechstars Ventures 2022
Curileum develops regenerative medicine therapies targeting intestinal stem cells to prevent colorectal cancer.
BiotechHealthtechMedical DevicesLondon, GB
Dr Jeff Moore(Founder & CEO)
Co-investorsAtlas VentureBiotechnology Value FundCanaan PartnersProspect Venture Partners
Cytecom develops a rapid diagnostic technology that detects viable bacteria in under a minute using a patented method of Optical Electrophysiology, combining fluorescent microscopy with electrical stimulation.
BiotechDeep TechMedical DevicesCoventry, GB
Dr. James Stratford(Co-Founder & CTO)Dr. Munehiro Asally(Academic Co-Founder)
digiLab builds AI and uncertainty quantification technology to help organisations and governments make decisions in high-stakes, safety-critical domains such as energy, critical infrastructure, cybersecurity, and environment when data is sparse or uncertain.
AI & Machine LearningDeep TechEnterprise Software
Tim Dodwell(Co-Founder & CEO)inAnhad Sandhu(Co-Founder & GM Saudi)inAndrew Corbett(Director of AI)inRory Scott Russell(Chief Growth Officer)in
BoardNigel Toon(Chairman)
Digistain develops imaging technology to grade breast cancer biopsies and assess cancer recurrence risk faster and more cost-effectively than traditional methods.
AI & Machine LearningHealthtechMedical DevicesLondon, GB
Hemmel Amrania(Founder)inChris Phillips(Founder)in
Co-investorsY Combinator
Entia develops at-home blood monitoring solutions for healthcare providers and patients.
Digital HealthHealthtechMedical Devices
Dr Toby Basey-Fisher(CEO & Founder)
Co-investorsSussex Place VenturesParkwalk Advisors
Etcembly builds EMLy Co-pilot, an AI platform with a conversational interface that unifies biologics design workflows—including structural modeling, variant generation, and molecule optimization—into a single tool.
AI & Machine LearningBiotechDeep TechHarwell, Oxfordshire, GB
Flarebright develops patented software and machine learning technologies that add capabilities such as autonomous flight and flight safety systems to robotic and crewed vehicles, including drones.
AI & Machine LearningDefense TechRoboticsUK, GB
Dr. Kelvin Hamilton(Founder & CEO)Dr. Conrad Rider(Co-founder & CTO)Dr. Carl Sequeira(Interim CTO)Gavin McEwan(Finance Director)in
Co-investorsOxford Investment Opportunity Network (OION)
Genevation develops personalized mRNA cancer vaccines using an AI-driven neoantigen discovery platform and cell-free manufacturing, with pre-clinical programs targeting lung, colon, and skin cancers.
AI & Machine LearningBiotechHealthtechStevenage, GB
Hydregen develops biocatalysis platform technologies that integrate into existing chemical manufacturing infrastructure, aiming to cut process costs by 40-50% while lowering energy use and carbon emissions.
BiotechCleantechNew Materials
Co-investorsClean Growth FundFuture Planet CapitalOxford Investment Opportunity Network (OION)UK Innovation & Science Seed Fund
Lucida Medical develops AI software to detect clinically significant prostate cancer from MRI scans, helping radiologists and physicians identify cancers, rule out patients who need no further investigation, and speed up the diagnostic pathway.
AI & Machine LearningDigital HealthMedical Devices
Anwar Padhani(Chief Medical Officer)
Co-investorsConduit ConnectIW CapitalOxford Investment Opportunity Network (OION)The FSE GroupXTX Markets
Mach42 develops AI tools for high-performance computing tasks, including analog circuit simulation and test plan development for semiconductors as well as real-time fusion control mechanisms.
AI & Machine LearningDeep TechSemiconductors
Co-investorsBusiness Growth FundForesight Group
Metacarpal builds body-powered, multi-articulating upper-limb prosthetic hands designed to be waterproof, durable, and reliable without charging.
HardwareHealthtechMedical Devices
Co-investorsGabriel Investment SyndicateOxfordScottish Enterprise
Metal Powder and Process Ltd develops and manufactures metal powders for critical manufacturing applications, offering gas atomised powders with tailored particle size distributions and optimised morphology.
Advanced ManufacturingHardwareNew Materials
MetalloBio is an antimicrobials development company creating a new class of metal-based, broad-spectrum antibacterial agents to treat drug-resistant "superbug" infections.
BiotechDeep TechHealthtechSheffield, GB
Kirsty Louise Smitten(Co-founder and first CEO)Professor Jim Thomas(Chief Scientific Advisor & Co-Founder)Dr Michael Murray(CEO)in
Co-investorsSeedrs
MitoRx is a preclinical-stage biotech developing MTRX31, a first-in-class small molecule that restores mitochondrial metabolism to eliminate ectopic fat in patients with metabolically unhealthy, high-risk obesity.
BiotechLongevityHarwell Oxford, GB
Jon R.(Founder)inJon Rees PhD(Co-founder & Chief Executive Officer)Norman Law PhD(Co-founder, Chief Technology Officer & Head of Intellectual Property)
Co-investorsFuture Planet CapitalOxford Investment Opportunity Network (OION)UK Innovation & Science Seed FundWren Capital
Neurolase develops AI-powered technology for brain surgery, aiming to improve surgical precision and patient outcomes in neurosurgery, particularly for brain tumor resection.
AI & Machine LearningDeep TechHealthtechMedical Devices
Monika Kott(Co-Founder & CEO)inBabar Vaqas(Co-Founder & CMO)in
Co-investorsZinc
Nikalyte manufactures physical vapor deposition (PVD) systems and instruments for thin-film and nanoparticle deposition serving research institutions, universities, and industrial customers.
AI & Machine LearningDeep TechHardwareNew Materials
Alistair Kean(Founder)inDave Mason(Founder)inSrinivasa Rao Saranu(Founder)inMark Vaughan(Founder)
ONI develops the Nanoimager, an automated super-resolution imaging system.
BiotechDeep TechHardwareMedical DevicesOxford, GB
Co-investorsAnjostARCH Venture PartnersArtis VenturesFuture Planet CapitalVertical Venture PartnersAxon Ventures+6 more
Orbit Discovery provides peptide discovery solutions for pharmaceutical and biotechnology companies, serving both large pharmaceutical firms and smaller biotech enterprises.
AI & Machine LearningBiotechDeep TechHealthtechOxford, GB
Co-investorsFuture Planet CapitalOxford Science EnterprisesPerivoli InnovationsBorealis Ventures
Unable to determine from the page provided.
BiotechHealthtechMedical DevicesTyler, US
Co-investorsAnjostBig Pi VenturesPerivoli InnovationsWinton Ventures
OVO Biomanufacturing offers a cloud-based software platform that helps viral vaccine manufacturers manage and reduce defective interfering particles (DIPs) to improve production yields.
Advanced ManufacturingBiotechSaaS
OxVent designs and produces a low-cost electro-mechanical medical ventilator, originally developed for the UK Government's 2020 Ventilator Challenge by engineers and medics from the University of Oxford and King's College London.
HardwareHealthtechMedical Devices
Prof Mark Thompson(Chair, Co-founder of OxVent)Prof Federico Formenti(Founding Director, Co-founder of OxVent)Paul Inness(CEO)in
Sustainable laundry service disrupting the traditional cleaning industry.
Co-investorsConduit ConnectOxford Investment Opportunity Network (OION)Sustainable VenturesTrueSight VenturesVala Capital
Pathfinder Bio uses enzyme engineering and low-cost protein production to develop biocatalysts and biotechnological processes for molecular biology reagents, diagnostics, and industrial biomanufacturing.
BiotechCircular EconomyDeep Tech
Polycat develops dry powder formulations that absorb and detoxify highly toxic liquids, including chemical warfare agents (CWAs), for defence, industry, and emergency response users.
CleantechDefense TechNew Materials
Process Vision develops optical measurement and imaging technology for the oil and gas industry, focused on improving process efficiency, reducing maintenance costs, and lowering emissions.
Deep TechEnergyIoTRobotics
Paul
Revolutionary Concepts Ltd designs and produces oil-free, modular multistage centrifugal air compressors and on-site nitrogen generation systems with patented interstage cooling to cut energy use by roughly 30%.
CleantechEnergyHardware
Refeyn develops mass photometry instruments that measure the mass of individual biomolecules in solution without labels, enabling analysis of protein purity, interactions, and viral vector characterization for research and manufacturing applications.
BiotechDeep TechHardwareMedical DevicesOxford, GB
Philipp Kukura(Founder)Dan Cole(Chief Scientist and co-founder)inJustin Benesch(Co-founder)in
Co-investorsOxford Science EnterprisesForesight GroupHorizons Ventures
Run3D provides gait analysis services aimed at runners looking to improve performance and avoid or recover from injury, along with a Walk3D offering for active walkers seeking to maintain mobility.
HealthtechSports TechWellness & Fitness
Sasets is a form management and data collection platform that enables organizations to create, deploy, and manage digital forms across mobile and desktop devices.
Cloud ComputingConstruction TechEnterprise SoftwareSaaS
Surrey Hydrogen develops green hydrogen production technology.
CleantechClimate TechEnergyNew MaterialsDidcot, GB
Dr Bahman Amini Horri(Founder & Advisor)Dakota Johnston(CEO & Founder)
Co-investorsFuture Planet CapitalUK Innovation & Science Seed Fund
TTP develops the Thermo Trauma Port, a novel patient transfer device for the trauma care pathway, created with a consortium including East Anglian Air Ambulance, University Hospital of Birmingham and the University of Portsmouth.
HardwareHealthtechMedical Devices
Mary Anne Cordeiro(Founder & CEO)in
Co-investorsAnglia Capital Group
Veirulence develops first-in-class non-antibiotic small molecule therapeutics that target bacterial virulence factors to treat resistant infections, with an initial focus on the WHO priority pathogen Pseudomonas aeruginosa.
BiotechDeep TechHealthtechLondon, GB
Rory Triniman, PhD(Founder)in
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
AbgentisAnimal DynamicsAsymmetric Suzuki ReactionsBioMotiCelsiusChamberTechConnexinCryoLogyxCytoSwimDarkbeamDermaSenseDesigner Carbon MaterialDucentisDucentis BioTherapeuticsDucentisbioENV EnergyEw TechnologiesIbexisLRESystemLupeMatildaMessage MissileMolecular WarehouseNeuroutePower OLEDsScintamScintam EngineeringSIME Clinical AISmarter NaturallySpendologyTheraport
Portfolio news
latest coverage across their companiesRefeyn · refeyn.com · Aug 11, 2026
MitoRx Therapeutics · globenewswire.com · Jun 9, 2026
Principals & officers · per Companies House
what is this? ⓘDirector · British
Director · Italian · since 2012
John Lucius Arthur Cary — 25–50% of shares
Frequently asked questions
- How many investments has Oxford Technology Management made?
- Oxford Technology Management has 77 tracked investments.
- What stage does Oxford Technology Management invest at?
- Oxford Technology Management invests at the Pre-Seed, Seed, Series A stages.
- What is Oxford Technology Management's typical check size?
- Oxford Technology Management typically writes checks of $200K – $400K.
- What sectors does Oxford Technology Management focus on?
- Oxford Technology Management focuses on Advanced Manufacturing, AgTech, AI & Machine Learning, Biotech, Cleantech, Data & Infrastructure, Deep Tech, Energy, Enterprise Software, Hardware, Healthtech, IoT, Medical Devices, New Materials, Robotics, SaaS, Sector Agnostic, Semiconductors, Space Tech.
- Where is Oxford Technology Management located?
- Oxford Technology Management is headquartered in Henley-on-Thames, GB.
- Does Oxford Technology Management lead rounds?
- Yes, Oxford Technology Management leads investment rounds.
- Who does Oxford Technology Management co-invest with?
- Oxford Technology Management most often shares deals with Future Planet Capital, Oxford Investment Opportunity Network (OION), UK Innovation & Science Seed Fund, among 36 tracked co-investors.
Media · Podcasts & interviews
featuring the teamMaster Investor Show 2024 – Lucius Cary and Andrea Mica – Oxford Technology Management Ltd
Master Investor · Lucius Cary
Master Investor Show 2023 – Lucius Cary and Andrea Mica – Oxford Technology Management Ltd
Master Investor · Lucius Cary
Images
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