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Oxford Technology Management

Venture capital

Henley-on-Thames · Pre-Seed–Series A · 5 people tracked

Also known as Grillcastle Limited · Seed Capital Limited

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Investment thesis

Oxford Technology specialises in seed and early-stage investing in science and technology startups located in and around Oxford, structured through SEIS and EIS funds that give investors generous UK tax reliefs and downside protection. Its flagship three-year fund spreads subscriptions across roughly eight SEIS startups with follow-on EIS funding for high performers, while a knowledge-intensive EIS fund invests in five more mature portfolio companies. The team emphasises a science-driven selection process, highly selective deal flow (about 5 in 1,000 per year) and hands-on involvement with founders in the early years to shape business models and pricing. It also runs WOTAN, an angel network offering co-investment opportunities.

Source: firm website, verified Sep 27, 2026.

Stage
Pre-Seed–Series A
Check
$200K – $400K
HQ
Henley-on-Thames, GB
Leads rounds
Leads
Instruments
Equity
Founded
1983
AUM
$33M
Tracked investments
77

Team · 5 people

from the firm's website & public directories

What they invest in

from 44 of 77 portfolio companies

Biotech ×20Healthtech ×20Medical Devices ×20Deep Tech ×16AI & Machine Learning ×14Hardware ×11New Materials ×6Cleantech ×5

HQs:United Kingdom×32United States×1

Who they back

founder profiles across 24 portfolio companies
42%
solo founders
10 of 24 mapped founding teams
12%
repeat founders
of 17 founders with career history

Founding team size:solo founder×102 founders×103 founders×34+ founders×1

Where their founders studiedfrom 18 founders with education data

Imperial College London ×4University of Oxford ×3University of Cambridge ×2

What their founders studiedfrom 21 founders with field-of-study data

Engineering ×6Life Sciences ×5Medicine ×4Economics ×3Mathematics & Statistics ×3Physics ×3Chemistry ×2

Where their founders worked beforefrom 17 founders with career history

MANTIS DEPOSITION LIMITED ×2University of Exeter ×2

13 founders hold a PhD (of 21 with degree data)

Investments · 77 tracked

founders shown can be your intro path

By year:2024 · 12017 · 12015 · 13 dated

ActiveNeedleactiveneedle.comin𝕏✓ verified

Active Needle Technology develops active (vibrating) needle technology to improve ultrasound-guided needle interventional procedures.

Deep TechHardwareHealthtechMedical Devices

Ian Quirk(Founder & CEO)inMuhammad Sadiq(Founder & Senior Technical Officer)in

Co-investorsOxford Investment Opportunity Network (OION)

Combatcombatcancer.comin𝕏✓ verified

Combat is a clinical-stage cancer treatment company focused on developing therapies for bladder and prostate cancer.

BiotechHealthtechMedical Devices

Edward Bruce-White(CEO/Co-Founder)inAlberto Martinez Albalat(Director of R&D, Founder and Chairman)

Co-investorsNW Angel

Septestseptest.com✓ verified

Septest develops rapid point-of-need diagnostic tests for detecting infections and inflammation, including its multi-marker TRISEP test aimed at pre-hospital and community triage.

BiotechHealthtechMedical Devices

​ OxCan (Oxford Cancer Analytics)oxcan.org

Oxford Cancer Analytics develops a diagnostics platform that combines reproducible proteomic measurement with AI to produce evidence-based insights supporting clinical decision-making.

AI & Machine LearningBiotechMedical DevicesOxford, GB

Andreas Halner(Founder and Head of Healthcare AI)inHeinrich Roder(Chief Technology Officer)inDaniel Szulc(Chief Product Officer)in

Co-investorsEka VenturesCross-Border Impact VenturesMeridian Health VenturesUK Innovation & Science Seed FundCivilization Ventures Management, LlcDigitalDx Ventures+1 more

Accelerateddiagnosticsaccelerateddiagnostics.com

Accelerated Diagnostics is developing decentralised diagnostics for human and veterinary markets, with a product launch planned for July 2026.

BiotechHealthtechMedical DevicesManchester, GB

Atelerix Seedatelerix.co.ukin𝕏

Atelerix develops hypothermic hydrogel encapsulation technology that stabilises and preserves fresh cells, tissues, and blood at room temperature, eliminating the need for cryopreservation and cold-chain logistics.

BiotechMedical DevicesNew Materials

Steve Swioklo(Founder)in

Co-investorsCambridge Angels groupFuture Planet CapitalO2h VenturesUK Innovation & Science Seed Fund

Beyondfencebeyondfence.eu

Beyond Fence provides ISO-compliant safety solutions for industrial robotics and automation, focused on keeping human operators safe and in control while improving efficiency.

Advanced ManufacturingHardwareRoboticsOxford, GB

Luc Yao, MBA, MSc(Managing Director)

Bioarchitechbioarchitech.comin

Bioarchitech develops oncolytic virus therapies and RNA-based immunotherapy candidates for cancer treatment.

AI & Machine LearningBiotechDeep TechHealthtech

Geoff Hale(Founder, Chairman)inLili Wang(Scientific Advisor & Co-founder)inHannah Chen(Scientific Advisor & Co-founder)

Covaticcovatic.comin𝕏

Covatic develops an on-device advertising platform powered by AI and machine learning that identifies user cohorts and delivers targeted ads while preserving consumer privacy.

AdTechAI & Machine LearningIoTLondon, GB

Nick Pinks(Founder)in

Co-investorsCreative UKTechstarsOxford Science EnterprisesTechstars Ventures 2022

Curileumcurileum.comin

Curileum develops regenerative medicine therapies targeting intestinal stem cells to prevent colorectal cancer.

BiotechHealthtechMedical DevicesLondon, GB

Dr Jeff Moore(Founder & CEO)

Co-investorsAtlas VentureBiotechnology Value FundCanaan PartnersProspect Venture Partners

Cytecomcytecom.co.uk

Cytecom develops a rapid diagnostic technology that detects viable bacteria in under a minute using a patented method of Optical Electrophysiology, combining fluorescent microscopy with electrical stimulation.

BiotechDeep TechMedical DevicesCoventry, GB

Dr. James Stratford(Co-Founder & CTO)Dr. Munehiro Asally(Academic Co-Founder)

digiLabdigilab.co.uk

digiLab builds AI and uncertainty quantification technology to help organisations and governments make decisions in high-stakes, safety-critical domains such as energy, critical infrastructure, cybersecurity, and environment when data is sparse or uncertain.

AI & Machine LearningDeep TechEnterprise Software

Tim Dodwell(Co-Founder & CEO)inAnhad Sandhu(Co-Founder & GM Saudi)inAndrew Corbett(Director of AI)inRory Scott Russell(Chief Growth Officer)in

BoardNigel Toon(Chairman)

Digistaindigistain.co.ukin𝕏

Digistain develops imaging technology to grade breast cancer biopsies and assess cancer recurrence risk faster and more cost-effectively than traditional methods.

AI & Machine LearningHealthtechMedical DevicesLondon, GB

Hemmel Amrania(Founder)inChris Phillips(Founder)in

Co-investorsY Combinator

Entiaentia.coin

Entia develops at-home blood monitoring solutions for healthcare providers and patients.

Digital HealthHealthtechMedical Devices

Dr Toby Basey-Fisher(CEO & Founder)

Co-investorsSussex Place VenturesParkwalk Advisors

Etcemblyetcembly.com

Etcembly builds EMLy Co-pilot, an AI platform with a conversational interface that unifies biologics design workflows—including structural modeling, variant generation, and molecule optimization—into a single tool.

AI & Machine LearningBiotechDeep TechHarwell, Oxfordshire, GB

Expendexpend.comin
Flare Brightflarebright.comin

Flarebright develops patented software and machine learning technologies that add capabilities such as autonomous flight and flight safety systems to robotic and crewed vehicles, including drones.

AI & Machine LearningDefense TechRoboticsUK, GB

Dr. Kelvin Hamilton(Founder & CEO)Dr. Conrad Rider(Co-founder & CTO)Dr. Carl Sequeira(Interim CTO)Gavin McEwan(Finance Director)in

Co-investorsOxford Investment Opportunity Network (OION)

Genevationgenevation.co.uk

Genevation develops personalized mRNA cancer vaccines using an AI-driven neoantigen discovery platform and cell-free manufacturing, with pre-clinical programs targeting lung, colon, and skin cancers.

AI & Machine LearningBiotechHealthtechStevenage, GB

Gripablegripable.coin

Able Rehab is a digital therapy platform that uses gamified activities to train hand and wrist movements for patients in rehabilitation.

Digital HealthHealthtechMedical Devices

Mike Mace(Founder)in

HydRegen Seedhydregenoxford.comin𝕏

Hydregen develops biocatalysis platform technologies that integrate into existing chemical manufacturing infrastructure, aiming to cut process costs by 40-50% while lowering energy use and carbon emissions.

BiotechCleantechNew Materials

Co-investorsClean Growth FundFuture Planet CapitalOxford Investment Opportunity Network (OION)UK Innovation & Science Seed Fund

Lucida Medicallucidamedical.com

Lucida Medical develops AI software to detect clinically significant prostate cancer from MRI scans, helping radiologists and physicians identify cancers, rule out patients who need no further investigation, and speed up the diagnostic pathway.

AI & Machine LearningDigital HealthMedical Devices

Anwar Padhani(Chief Medical Officer)

Co-investorsConduit ConnectIW CapitalOxford Investment Opportunity Network (OION)The FSE GroupXTX Markets

Machine Discoverymachine-discovery.com

Mach42 develops AI tools for high-performance computing tasks, including analog circuit simulation and test plan development for semiconductors as well as real-time fusion control mechanisms.

AI & Machine LearningDeep TechSemiconductors

Co-investorsBusiness Growth FundForesight Group

Metacarpalmetacarpal.co.ukSep 2024

Metacarpal builds body-powered, multi-articulating upper-limb prosthetic hands designed to be waterproof, durable, and reliable without charging.

HardwareHealthtechMedical Devices

Co-investorsGabriel Investment SyndicateOxfordScottish Enterprise

Metal Powder and Processmetalpowderprocess.co.uk

Metal Powder and Process Ltd develops and manufactures metal powders for critical manufacturing applications, offering gas atomised powders with tailored particle size distributions and optimised morphology.

Advanced ManufacturingHardwareNew Materials

Metallobiometallobio.comin

MetalloBio is an antimicrobials development company creating a new class of metal-based, broad-spectrum antibacterial agents to treat drug-resistant "superbug" infections.

BiotechDeep TechHealthtechSheffield, GB

Kirsty Louise Smitten(Co-founder and first CEO)Professor Jim Thomas(Chief Scientific Advisor & Co-Founder)Dr Michael Murray(CEO)in

Co-investorsSeedrs

MitoRx Therapeuticsmitorxtherapeutics.comin

MitoRx is a preclinical-stage biotech developing MTRX31, a first-in-class small molecule that restores mitochondrial metabolism to eliminate ectopic fat in patients with metabolically unhealthy, high-risk obesity.

BiotechLongevityHarwell Oxford, GB

Jon R.(Founder)inJon Rees PhD(Co-founder & Chief Executive Officer)Norman Law PhD(Co-founder, Chief Technology Officer & Head of Intellectual Property)

Co-investorsFuture Planet CapitalOxford Investment Opportunity Network (OION)UK Innovation & Science Seed FundWren Capital

Neurolaseneurolase.comin

Neurolase develops AI-powered technology for brain surgery, aiming to improve surgical precision and patient outcomes in neurosurgery, particularly for brain tumor resection.

AI & Machine LearningDeep TechHealthtechMedical Devices

Monika Kott(Co-Founder & CEO)inBabar Vaqas(Co-Founder & CMO)in

Co-investorsZinc

Nikalytenikalyte.comin𝕏

Nikalyte manufactures physical vapor deposition (PVD) systems and instruments for thin-film and nanoparticle deposition serving research institutions, universities, and industrial customers.

AI & Machine LearningDeep TechHardwareNew Materials

Alistair Kean(Founder)inDave Mason(Founder)inSrinivasa Rao Saranu(Founder)inMark Vaughan(Founder)

ONIoni.bioin𝕏

ONI develops the Nanoimager, an automated super-resolution imaging system.

BiotechDeep TechHardwareMedical DevicesOxford, GB

Co-investorsAnjostARCH Venture PartnersArtis VenturesFuture Planet CapitalVertical Venture PartnersAxon Ventures+6 more

Orbit Discoveryorbitdiscovery.comin𝕏

Orbit Discovery provides peptide discovery solutions for pharmaceutical and biotechnology companies, serving both large pharmaceutical firms and smaller biotech enterprises.

AI & Machine LearningBiotechDeep TechHealthtechOxford, GB

Neil Butt(CEO)in

Co-investorsFuture Planet CapitalOxford Science EnterprisesPerivoli InnovationsBorealis Ventures

Orthosonorthoson.comJan 2017

Unable to determine from the page provided.

BiotechHealthtechMedical DevicesTyler, US

Co-investorsAnjostBig Pi VenturesPerivoli InnovationsWinton Ventures

Ovobiomanufacturingovobiomanufacturing.com

OVO Biomanufacturing offers a cloud-based software platform that helps viral vaccine manufacturers manage and reduce defective interfering particles (DIPs) to improve production yields.

Advanced ManufacturingBiotechSaaS

Oxventoxvent.orgin𝕏

OxVent designs and produces a low-cost electro-mechanical medical ventilator, originally developed for the UK Government's 2020 Ventilator Challenge by engineers and medics from the University of Oxford and King's College London.

HardwareHealthtechMedical Devices

Prof Mark Thompson(Chair, Co-founder of OxVent)Prof Federico Formenti(Founding Director, Co-founder of OxVent)Paul Inness(CEO)in

Oxwashoxwash.com

Sustainable laundry service disrupting the traditional cleaning industry.

Co-investorsConduit ConnectOxford Investment Opportunity Network (OION)Sustainable VenturesTrueSight VenturesVala Capital

Pathfinder Biopathfinderbio.co.uk

Pathfinder Bio uses enzyme engineering and low-cost protein production to develop biocatalysts and biotechnological processes for molecular biology reagents, diagnostics, and industrial biomanufacturing.

BiotechCircular EconomyDeep Tech

Polycatpolycat.co.uk

Polycat develops dry powder formulations that absorb and detoxify highly toxic liquids, including chemical warfare agents (CWAs), for defence, industry, and emergency response users.

CleantechDefense TechNew Materials

Processvisionprocessvision.comin𝕏

Process Vision develops optical measurement and imaging technology for the oil and gas industry, focused on improving process efficiency, reducing maintenance costs, and lowering emissions.

Deep TechEnergyIoTRobotics

Paul

RCLrevolutionaryconcepts.co.uk

Revolutionary Concepts Ltd designs and produces oil-free, modular multistage centrifugal air compressors and on-site nitrogen generation systems with patented interstage cooling to cut energy use by roughly 30%.

CleantechEnergyHardware

Refeynrefeyn.comin

Refeyn develops mass photometry instruments that measure the mass of individual biomolecules in solution without labels, enabling analysis of protein purity, interactions, and viral vector characterization for research and manufacturing applications.

BiotechDeep TechHardwareMedical DevicesOxford, GB

Philipp Kukura(Founder)Dan Cole(Chief Scientist and co-founder)inJustin Benesch(Co-founder)in

Co-investorsOxford Science EnterprisesForesight GroupHorizons Ventures

Run3Drun3d.co.uk

Run3D provides gait analysis services aimed at runners looking to improve performance and avoid or recover from injury, along with a Walk3D offering for active walkers seeking to maintain mobility.

HealthtechSports TechWellness & Fitness

Sasetssasets.com

Sasets is a form management and data collection platform that enables organizations to create, deploy, and manage digital forms across mobile and desktop devices.

Cloud ComputingConstruction TechEnterprise SoftwareSaaS

Simedxsimedx.comin𝕏

SimedX operates an AI-powered intensive care platform that uses clinical data to provide decision support for acute respiratory care in critical care settings.

AI & Machine LearningDigital HealthHealthtechMedical Devices

Surrey H2 Funding Raisedsurreyh2.com

Surrey Hydrogen develops green hydrogen production technology.

CleantechClimate TechEnergyNew MaterialsDidcot, GB

Dr Bahman Amini Horri(Founder & Advisor)Dakota Johnston(CEO & Founder)

Co-investorsFuture Planet CapitalUK Innovation & Science Seed Fund

Thermo Trauma Portthermotraumaport.com

TTP develops the Thermo Trauma Port, a novel patient transfer device for the trauma care pathway, created with a consortium including East Anglian Air Ambulance, University Hospital of Birmingham and the University of Portsmouth.

HardwareHealthtechMedical Devices

Mary Anne Cordeiro(Founder & CEO)in

Co-investorsAnglia Capital Group

Veirulenceveirulence.com

Veirulence develops first-in-class non-antibiotic small molecule therapeutics that target bacterial virulence factors to treat resistant infections, with an initial focus on the WHO priority pathogen Pseudomonas aeruginosa.

BiotechDeep TechHealthtechLondon, GB

Rory Triniman, PhD(Founder)in

Zaynduzayndu.com

Zayndu manufactures and operates ActivatedAir™, a proprietary system for controlled environment agriculture that enhances seed treatment and plant growth.

AgTechCleantechDeep TechFoodTechHardware

Felipe Iza(Founder)in

Other

Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.

AbgentisAnimal DynamicsAsymmetric Suzuki ReactionsBioMotiCelsiusChamberTechConnexinCryoLogyxCytoSwimDarkbeamDermaSenseDesigner Carbon MaterialDucentisDucentis BioTherapeuticsDucentisbioENV EnergyEw TechnologiesIbexisLRESystemLupeMatildaMessage MissileMolecular WarehouseNeuroutePower OLEDsScintamScintam EngineeringSIME Clinical AISmarter NaturallySpendologyTheraport

Portfolio news

latest coverage across their companies

Principals & officers · per Companies House

what is this? ⓘ
John Lucius Arthur Cary

Director · British

Andrea Giacomo Mica

Director · Italian · since 2012

Ownership & control

John Lucius Arthur Cary — 25–50% of shares

Frequently asked questions

How many investments has Oxford Technology Management made?
Oxford Technology Management has 77 tracked investments.
What stage does Oxford Technology Management invest at?
Oxford Technology Management invests at the Pre-Seed, Seed, Series A stages.
What is Oxford Technology Management's typical check size?
Oxford Technology Management typically writes checks of $200K – $400K.
What sectors does Oxford Technology Management focus on?
Oxford Technology Management focuses on Advanced Manufacturing, AgTech, AI & Machine Learning, Biotech, Cleantech, Data & Infrastructure, Deep Tech, Energy, Enterprise Software, Hardware, Healthtech, IoT, Medical Devices, New Materials, Robotics, SaaS, Sector Agnostic, Semiconductors, Space Tech.
Where is Oxford Technology Management located?
Oxford Technology Management is headquartered in Henley-on-Thames, GB.
Does Oxford Technology Management lead rounds?
Yes, Oxford Technology Management leads investment rounds.
Who does Oxford Technology Management co-invest with?
Oxford Technology Management most often shares deals with Future Planet Capital, Oxford Investment Opportunity Network (OION), UK Innovation & Science Seed Fund, among 36 tracked co-investors.

Media · Podcasts & interviews

featuring the team

Master Investor Show 2024 – Lucius Cary and Andrea Mica – Oxford Technology Management Ltd

Master Investor · Lucius Cary

Master Investor Show 2023 – Lucius Cary and Andrea Mica – Oxford Technology Management Ltd

Master Investor · Lucius Cary

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