Cardinal Partners
Venture capitalPrinceton · Seed–Growth · 8 people tracked
Also known as CHP MANAGEMENT, INC.
Investment thesis
Cardinal Partners focuses on early and growth stage healthcare investing, backing disruptive healthcare technology-enabled services and life sciences companies. The firm often serves as the first institutional investor and occasionally plays a co-founding role at inception. Its thesis is driven by ongoing change across healthcare systems, insurance, and regulatory reform, favoring companies that deliver more care to more people at lower cost. Cardinal emphasizes deep healthcare investing experience, strong academic, clinical, industry, and investment networks, and sustained engagement with portfolio companies to build durable, valuable businesses through multiple economic cycles.
Source: firm website, verified Aug 3, 2026.
Team · 8 people
from the firm's website & public directories
What they invest in
from 12 of 18 portfolio companiesHealthtech ×9Biotech ×7Medical Devices ×7Digital Health ×4Enterprise Software ×3AI & Machine Learning ×2Data & Infrastructure ×1Deep Tech ×1
HQs:United States×9Denmark×1
Investments · 18 tracked
founders shown can be your intro pathaTyr is a clinical-stage biotechnology company developing therapies derived from tRNA synthetase biology to treat fibrosis and inflammation, with its lead candidate efzofitimod in clinical trials for interstitial lung disease.
BiotechHealthtechMedical DevicesSan Diego, US
Amir Nashat(Non-Management Director)Paul Schimmel(Non-Management Director)Akkaraju Srinivas(Non-Management Director)John D. Mendlein(Executive Officer, Director)David Weiner(Executive Officer)Ed Penhoet(Non-Management Director)
Board seatPaul SchimmelJohn Clarke· per SEC Form D
Teladoc Health operates a virtual care platform connecting patients with care providers for medical care, mental health, and chronic disease management services.
Digital HealthHealthtechMental HealthPurchase, US
Dana Mead(Director)James Outland(Director)Michael King(Executive Officer)Martin Felsenthal(Director)Mark Hirschhorn(Executive Officer)Jason Gorevic(Executive Officer, Director)
Board seatThomas G. McKinley· per SEC Form D
Alkermes develops pharmaceutical medicines for psychiatric and neurological disorders, including addiction, serious mental illness, and sleep disorders.
BiotechHealthtechMedical Devices
PartnerJohn Clarke· led
Privia Health operates a network of physician practices organized for value-based care delivery, supporting independent practices and physicians across multiple specialties while maintaining clinical autonomy.
Data & InfrastructureDigital HealthEnterprise SoftwareHealthtechSaaS<UNKNOWN>
Verastem Oncology is a biopharmaceutical company that discovers and develops drugs to treat cancer patients.
BiotechMedical DevicesNeedham, US
Robert WeinbergTIMOTHY BARBERICH(Director)ALISON LAWTON(Director)ERIC ROWINSKY(Director)BRUCE WENDEL(Director)GINA CONSYLMAN(Director)
PartnerJohn Clarke· led
Palo Alto, US
Mark Smith(Director)Elizabeth Spaulding(Director)Kent Marquardt(Director)Thomas McKinley(Director)Linda T. Hand(Executive Officer, Director)Niall O'Cathasaigh(Executive Officer)
Board seatJohn Clarke· per SEC Form D · $2M raise · filed Mar 2018
Alnylam is a biopharmaceutical company that supports investigator-initiated studies in therapeutic areas including transthyretin-mediated amyloidosis, acute hepatic porphyria, and primary hyperoxaluria for medical researchers and healthcare professionals.
BiotechDigital HealthMedical Devices
Cloud-based healthcare platform for clinical workflows
New York, US
Joseph Mayer(Director)James Bradley(Director)Bharath Ganesan(Director)Richard Resnick(Executive Officer, Director)Todd Pietri(Director)
BoardJohn Clarke(Director)
Ivenix makes an intelligent infusion pump system for hospital settings that delivers intravenous medications to patients while incorporating safeguards to reduce medication errors.
BiotechHealthtechMedical DevicesAmesbury, US
Ketan Patel(Director)John M. Douglass(Director)John Sokolowski(Executive Officer)John K. Clarke(Director)Jesse Ambrosina(Executive Officer)Colin J. Foster(Director)
Intelerad provides medical imaging software and healthcare IT solutions that connect physicians across the patient journey.
Enterprise SoftwareHealthtechMedical Devices
Hamid Tabatabaie(Executive Officer, Director, Promoter)David Jahns(Director)Thomas McKinley(Director)William Cowen(Director)
Prealize develops AI and machine learning solutions for healthcare providers and health plans to enable proactive, prediction-driven care rather than reactive treatment.
AI & Machine LearningDigital HealthHealthtechInsurTechStanford, US
BoardDr. Arnold MilsteinDr. Nigam Shah
Lundbeck is a global pharmaceutical company specializing in researching, developing, manufacturing, and commercializing medications for brain diseases and neurological conditions.
BiotechHealthtechMedical DevicesCopenhagen, DK
Zelis provides financial technology solutions purpose-built for healthcare payers, providers, and members, with capabilities spanning network management, member engagement, claims optimization, payments, and communications.
Enterprise SoftwareFintechHealthtech
Vividion Therapeutics develops small molecule therapeutics using a covalent-first chemoproteomics approach to identify and target previously undruggable proteins.
AI & Machine LearningBiotechDeep TechPrinceton, US
Ben Cravatt(Scientific Founder)Phil Baran(Scientific Founder)Jin-Quan Yu(Scientific Founder)John Park(Executive Officer)John Clarke(Executive Officer, Director)
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.
Fund performance · per public LP disclosures
as of Jun 2025| Fund | Vintage | Committed | Net IRR | TVPI | DPI |
|---|---|---|---|---|---|
| Cardinal NR Sidecar HoldingsLPs: New York City Fire Department Pension Fund, New York City Board of Education Retirement System | 2018 | — | 17.2% | — | 0.45x |
Source: public limited-partner disclosures (CalPERS, CalSTRS). Net IRR / TVPI / DPI as reported by the limited partner; a fund's early-year IRR is an interim estimate (J-curve).
Frequently asked questions
- What stage does Cardinal Partners invest at?
- Cardinal Partners invests at the Seed, Series A, Series B, Growth stages.
- What sectors does Cardinal Partners focus on?
- Cardinal Partners focuses on Biotech, Digital Health, Healthtech, Medical Devices.
- Where is Cardinal Partners located?
- Cardinal Partners is headquartered in Princeton, US.
- Does Cardinal Partners lead rounds?
- Yes, Cardinal Partners leads investment rounds.
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