Cambridge · Pre-Seed–Series A · 19 people tracked
Also known as Takeda
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Investment thesis
Takeda Ventures invests in early-stage, preclinical therapeutic and platform-based companies whose science complements Takeda's pipeline. As a strategic corporate investor, it partners with academic innovators, entrepreneurs and venture investors to build and nurture companies aligned with Takeda's R&D pillars: Oncology, Rare Genetics & Hematology, Neuroscience, and Gastrointestinal and Inflammation. The goal is to support therapeutic innovation by giving portfolio companies access to the resources of a multinational pharmaceutical company while generating disruptive technologies and treatments for patients.
Source: firm website, verified Aug 3, 2026.
Team · 19 people
from the firm's website & public directoriesFounder mafia
4 people who came through Takeda Ventures went on to found or lead other companies.
What they invest in
from 26 of 32 portfolio companiesBiotech ×18Healthtech ×16Digital Health ×8Medical Devices ×5AI & Machine Learning ×3Deep Tech ×3Mental Health ×1SaaS ×1
HQs:United States×22Netherlands×1
Investments · 32 tracked
founders shown can be your intro pathBy year:2024 · 12023 · 32022 · 52021 · 12020 · 12019 · 12018 · 22017 · 12014 · 217 dated
Quince Therapeutics is a biotechnology company developing the AIDE technology platform, a drug/device combination that encapsulates medications into a patient's own red blood cells to improve drug delivery for rare diseases.
BiotechSouth San Francisco, US
Stephen Dominy(Director)Casey Lynch(Executive Officer, Director)Charles Ryan(Executive Officer)inBrendan Hannah(Executive Officer)Dirk Thye(Executive Officer, Director)inKristen Gafric(Executive Officer)
Co-investorsForesite CapitalSofinnova Partners
Xilio Therapeutics is a clinical-stage biotechnology company developing masked immuno-oncology therapies that use protein engineering to remain inactive until activated by tumor-specific proteases within the tumor microenvironment.
BiotechHealthtechWaltham, US
René Russo(Executive Officer, Director)inJoseph Farmer(Executive Officer)Timothy Clackson(Executive Officer)Christopher Frankenfield(Chief Financial and Operating Officer)inKatarina Luptakova(Chief Medical Officer)inPaul Clancy(Director)
Co-investorsBain Capital Life SciencesBay City CapitalF-Prime CapitalM VenturesMRL Ventures FundRA Capital+9 more
EvolveImmune develops immunotherapy treatments for cancer patients.
BiotechHealthtechMedical DevicesBranford, US
Stephen Bloch(Co-founder and Chief Executive Officer)inDonmienne Leung(Manager)Ian Taylor(Manager)Jay Fine(President, Research and Development)
BoardDerek Yoon(Manager)in
Board seatJasmina Marjanovic· per SEC Form D
Co-investorsSolasta VenturesPfizer VenturesElm Street VenturesPfizer Venture Investments
BiotechSan Diego, US
Douglas J. Jolly(Founder)inCarlos E. Ibanez(Executive Officer)Robert Anthony Williamson(Director)Troy Wilson(Director)Michael Martin(Director)Nicholas A. Boyle, Ph.D.(Executive Officer, Director)
Co-investorsBioBrit
Telemedicine services for health systems, health plans, employers, and physicians
Co-investorsAllianz XLG Technology VenturesMcKesson VenturesP5 Health VenturesPerot JainWaterline Ventures+1 more
HealthtechSaratoga Springs, US
Daniel T. Pickett III(Executive Officer, Director)Timothy Koehler(Executive Officer)Greg Stephen(Executive Officer)
BoardHolly Benson(Director)Mary Langowski(Director)Peter Dorsman(Director)
Co-investorsClaritas CapitalWhat If VenturesOlive Tree VenturesPivotal Life SciencesVista Equity Partners
Arcellx develops CAR T-cell therapies that are individually designed for each patient, using the immune system to target and attack cancer.
BiotechHealthtechGaithersburg, US
Han Lee(Executive Officer)Rami Elghandour(Executive Officer, Director)in
BoardJill Carroll(Director)inAli Behbahani(Director)inDerek Yoon(Director)inTiba Aynechi(Director)in
Co-investorsLG Technology VenturesNew Enterprise Associates (NEA)Quan CapitalSamsara BioCapitalSixty Degree CapitalSolasta Ventures+5 more
Aspen RxHealth operates a community of pharmacists to deliver clinical pharmacy care and medication support for patients and health plan members.
Digital HealthHealthtechSaaS
Co-investorsBessemer Venture PartnersFlare Capital Partners
Biofourmis provides technology-enabled solutions and a platform for AI-driven in-home patient care, using wearable biosensors and remote monitoring to deliver and transition patients across levels of care.
AI & Machine LearningDigital HealthHealthtech
Kuldeep Singh Rajput(Founder)in
Co-investorsIntel CapitalCVS Health VenturesGeneral AtlanticMassMutual VenturesOpenspace Ventures
Boulder provides medication-assisted treatment for addiction through licensed specialists who prescribe buprenorphine, supported by dedicated care teams offering medical care, peer recovery coaching, and care coordination accessible via a digital platform.
Digital HealthHealthtechMental HealthBoulder, US
Stephanie Papes(Cofounder)Stephanie Strong(Founder)Jordan Nof(Director)Frank Ingari(Director)Josh Kopelman(Director)
Co-investorsAdvance Venture PartnersAlumni VenturesFirst Round CapitalGreycroftLaerdal Million Lives FundQiming Venture Partners USA+4 more
Code Biotherapeutics develops a proprietary non-viral 3DNA delivery platform for genetic medicines, RNAi, and other modalities, using targeting molecules to reach specific cells and tissues outside the liver.
BiotechDeep TechHealthtechHatfield, US
Lauren Kaskiel(Executive Officer)inRobert C. Getts(Executive Officer)Brian McVeigh(Executive Officer, Director)in
BoardDmitry Kuzmin(Director)Victor Stone(Director)Edward Mathers(Director)
Co-investorsNew Enterprise Associates (NEA)4BIO CapitalAmgen VenturesHatteras Venture PartnersJDRF T1D FundNorthpond Ventures+1 more
Crescendo Biologics develops novel immune cell-enhancing therapeutics for immuno-oncology using its patent-protected Humabody VH platform, a fully human domain technology clinically validated in oncology and immunology.
BiotechHealthtechMedical Devices
Co-investorsAndera PartnersQuan CapitalSofinnova PartnersAstellas Venture Management LLCEMBL VenturesFuture Planet Capital+3 more
Ensoma is a genomic medicine company developing a platform for in vivo engineering of hematopoietic stem cells (HSCs), combining an off-the-shelf delivery system with a gene engineering toolkit intended to treat diseases with a one-time treatment.
BiotechHealthtechMedical DevicesBoston, US
Albert Seymour(Director)
BoardKush Parmar(Executive Officer, Director)inPaula Soteropoulos(Director)Stephen Knight(Director)in
Co-investors5AM VenturesAju IB InvestmentCatalio Capital Management, LPDelos CapitalF-Prime CapitalSolasta Ventures+10 more
Enzyre develops a handheld diagnostic device that performs multiple blood coagulation assays in parallel to identify bleeding causes at the point of care.
BiotechDeep TechDigital HealthHealthtechMedical DevicesEindhoven, NL
Wim van den Broek(CEO)inWaander(CSO)
Co-investorsi&i Biotech FundNovalis BiotechOost NL
Cambridge, MA biotech developing engineered tRNA "protein editing" therapeutics for nonsense-mutation diseases; reported shut down in 2025.
Cambridge, US
Leslie J Williams(Executive Officer, Director)
BoardBenjamin Chen(Director)Seiji Miyahara(Director)inSacha Mann(Director)David Moskowitz(Director)Steven Gillis(Director)in
Co-investorsARCH Venture Partners5AM Ventures8VCAtlas VenturePanacea VentureTaiho Ventures, LLC
ISHI offers a discharge transitions program that manages patient recovery during the post-hospital period with personalized care coordination and clinical insights for care teams and healthcare administrators.
AI & Machine LearningDigital HealthHealthtech
Dr. Ajay Srivastava(Founder)
Nabla is a drug development company that applies design discipline and scientific rigor to the development of new medicines.
AI & Machine LearningBiotechDeep TechHealthtechBoston, US
Surge Biswas(Founder)inFrances Anastassacos(Founder)inGeorge M. Church(Founder)Surge Biswas Frances Anastassacos(Founder)
Co-investorsCantos VenturesFifty YearsPetriPillar VCRadical VenturesSparta Group+6 more
Clinical-stage immuno-oncology company developing antibodies derived from the immune systems of 'Elite' cancer responders.
BiotechHouston, US
Alice Bexon(Executive Officer)inClifford J. Stocks(Director, Executive Officer)inKamal D. Puri(Executive Officer)inChris Russell(Executive Officer)inRuss Hawkinson(Executive Officer)
BoardSteven Gillis(Director)in
Co-investors3B Future Health FundCanaan PartnersGreatPoint VenturesRiverVest Venture PartnersAlexandriaARCH Venture Partners+5 more
Oshi provides virtual gastrointestinal care delivered by gastroenterologists, dietitians, and gut-brain specialists to patients seeking treatment for GI conditions.
Digital HealthHealthtech
Sam Holliday(CEO)in
Co-investorsBessemer Venture PartnersCVS Health VenturesFlare Capital PartnersFrist Cressey VenturesKoch Disruptive TechnologiesOak HC/FT+1 more
Palleon Pharma develops small molecule and biologic drugs targeting autoimmune and inflammatory diseases using proprietary glycoscience platforms.
BiotechDigital HealthMedical DevicesWaltham, US
Jim Broderick(Co-Founder)inJohn Hennessy(Executive Officer)Karen Hong(Director)James Lee(Director)Stephen Hoffman(Director)Li Peng(Chief Scientific Officer)
Co-investorsMatrix Capital ManagementPfizer VenturesPfizer Venture InvestmentsSR One Capital ManagementBioHealth Innovation, Inc.Vertex Ventures HC
BiotechLexington, US
Victoria M. Richon(Executive Officer, Director)in
BoardCameron Wheeler(Director)Jonathan Root(Director)Laurence Lasky(Director)
Co-investorsAvego BioScience CapitalOUP (Osage University Partners)Peregrine VenturesAbbVieDeerfield Management CompanyJJDC+4 more
Tele911 connects patients on scene with board-certified emergency medicine physicians via telehealth, bridging the gap between a 911 call and the emergency department to triage cases and reduce unnecessary ambulance and ER use.
Digital HealthHealthtechPasadena, US
Ramon Lizardo(Executive Officer)inChristopher Maloney(Executive Officer, Director, Promoter)Marc Eckstein(Executive Officer, Director)
BoardJeff Trost(Director)inBruce Meadows(Director)
Co-investorsLaerdal Million Lives Fund
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
ArmaGenBE BiopharmaBionizJuventas TherapeuticsKoneksa HealthMaia OncologyOrphoMedRedpin TherapeuticsRedwood Bioscience
Exits · 4
2 IPOs · 2 acquisitions · showing 3Quince TherapeuticsNASDAQ: QNCXXilio TherapeuticsNASDAQ: XLORedwood Bioscienceacq. by Catalent Pharma Solutions
Portfolio news
latest coverage across their companiesEnsoma · finsmes.com · Sep 23, 2025
Palleon Pharmaceuticals · nasdaqprivatemarket.com · Jun 27, 2025
IPO stake values · per SEC filings · 2
Value of this firm's stake in each portfolio company at its IPO price, from the prospectus principal-stockholder table.
| Company | Owned | IPO price | At IPO | Stake value |
|---|---|---|---|---|
| Quince Therapeutics | 10.2% | $17.00 | May 2019 | $45.6M |
| Xilio Therapeutics | 5.5% | $16.00 | Oct 2021 | $23.6M |
Source: SEC S-1 / 424B prospectus filings. Stake value = shares beneficially owned × the initial public offering price, as disclosed — a market value at IPO, not a return multiple (the firm's original cost is not disclosed).
Frequently asked questions
- How many investments has Takeda Ventures made?
- Takeda Ventures has 32 tracked investments, 4 of which have exited, including 1 dated in the last 24 months.
- What stage does Takeda Ventures invest at?
- Takeda Ventures invests at the Pre-Seed, Seed, Series A stages.
- What is Takeda Ventures's typical check size?
- Takeda Ventures typically writes checks of $1M – $5M.
- What sectors does Takeda Ventures focus on?
- Takeda Ventures focuses on Biotech, Healthtech, Medical Devices.
- Where is Takeda Ventures located?
- Takeda Ventures is headquartered in Cambridge, US.
- Does Takeda Ventures lead rounds?
- Takeda Ventures typically participates in rounds rather than leading them.
Co-investors · 2
4BIO Capital is a London-based venture capital firm investing in life sciences, with a focus on advanced therapies that address high unmet medical and social needs.
McKesson Ventures is the corporate venture arm of McKesson, one of the largest healthcare companies in the world, investing in software and services companies for the healthcare and pharma industries.
Firms observed investing alongside Takeda Ventures, from public investor directories. Shared companies are the overlap with Takeda Ventures's recorded portfolio.
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