Fundraising Fox

Illinois Ventures

Venture capital

Champaign · Pre-Seed–Late Stage · 21 people tracked

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Investment thesis

Illinois Ventures backs early-stage companies across a broad range of founders, from deep tech teams building solutions in a lab, to student coders, to seasoned entrepreneurs. The firm positions itself as a hands-on partner with a veteran team that helps portfolio companies advance from a pioneering venture to a successful exit. Its stated mission is to make the world a better and more connected place.

Source: firm website, verified Aug 3, 2026.

Stage
Pre-Seed–Late Stage
HQ
Champaign, Illinois, US
Instruments
Equity
Founded
2000
AUM
$25M
Tracked investments
55

Team · 21 people

from the firm's website & public directories
Thomas Parkinson· Venture Partnerin
Dennis Hesch· Chairman, Executive VP, The Carle Systemin
Dr. Deb Paul· Director, Business Development & Licensing, Abbott Laboratories (Retired)
Dr. Guy Padbury· SVP, Oncology Clinical Pharmacologyin
Dr. Jay Walsh· Vice President for Economic Development and Innovation, University of Illinoisin
Dr. Paul Ellinger· VP, CFO and Comptroller, University of Illinois (Ex-officio)in
Michael T. Tokarz· Chairman & CEO, Tokarz Group
Nathan Hoffman· Director, Office of Technology Management, University of Illinois Urbana-Champaignin
Sarah Phalen· President and CEO, INBin

What they invest in

from 40 of 55 portfolio companies

Medical Devices ×14Biotech ×12Healthtech ×12AI & Machine Learning ×10Deep Tech ×9Hardware ×7Digital Health ×5Enterprise Software ×4

HQs:United States×32

Investments · 55 tracked

founders shown can be your intro path

By year:2024 · 22023 · 22020 · 12017 · 16 dated

Actuate Therapeuticsactuatetherapeutics.comin𝕏NASDAQ: ACTU

Clinical-stage therapeutics company focusing on high-impact cancers and inflammatory diseases.

BiotechFort Worth, US

Daniel Schmitt(Executive Officer, Director)Andrew Mazar(Executive Officer)Paul Lytle(Executive Officer)Leslie Wayne Kreis, Jr.(Director, Promoter)

BoardTodd Thomson(Director)Roger Sawhney(Director)

Amber Agricultureamber.agin

Amber produces wireless, solar-powered automation kits for grain bin monitoring and fan control that replace traditional cable systems.

AgTechHardwareIoTChicago, US

Lucas Frye(Executive Officer, Director, Promoter)Cyril Ebersweiler(Incoming Series Seed Director.)Joseph Varikooty(Executive Officer, Director, Promoter)

Apriority Financialapriority.aiin

Apriority offers a membership-based platform that helps individual borrowers manage and monitor their loans, continuously scanning lenders for lower rates and rate dips while redirecting referral commissions that normally go to intermediary platforms back to the member.

AI & Machine LearningConsumerFintechRedwood City, US

Aptimmune Biologicsaptimmune.com𝕏Jun 2017

Aptimmune develops vaccines for swine health, partnering with vaccine development and swine health consulting companies to speed product development, testing and manufacturing.

AgTechBiotechHealthtechChampaign, US

Robert Easter(Director)Paul Olivo(Director)Aaron Gilbertie(CEO)Gary Durack(Director)Federico Zuckermann(Executive Officer, Director)

Ascent Integrated Techascentitech.com
Auvi Labsauvilabs.com
Beyond Barriers Therapeuticsbeyondbarrierstherapeutics.com

Beyond Barriers Therapeutics develops BBT-101, an intranasal therapy for mild and moderate concussions intended for rapid deployment at the point of injury.

BiotechDigital HealthMedical Devices

Brink Biologicsbrinkbiologics.comin

Brink Biologics provides NK-92 cell lines and assay panels for antibody-dependent cell-mediated cytotoxicity (ADCC) testing in therapeutic antibody development.

BiotechDeep TechMedical DevicesSan Diego, US

BYLD Innovationsbyld-innovations.com

BYLD Innovations develops portable and foldable 3D printers for engineers requiring on-demand and on-site printing capabilities.

Advanced ManufacturingHardware

Cadenza Biocadenza.bioinDec 2023

Cadenza Bio develops small-molecule drugs for oral administration to treat demyelinating and inflammatory diseases.

BiotechFemTechMedical DevicesYukon, US

Carol Curtis, PhD(Chief Executive Officer, Founder)Elaine Hamm, PhD(Chief Operating Officer, Founder)John Katzenellenbogen, PhD(Scientific Founder)Seema Tiwari-Woodruff, PhD(Scientific Founder)Elaine Hamm(Executive Officer, Director)Carol Curtis(Executive Officer, Director)

Cast21cast21.comin𝕏

HealthtechMemphis, US

Ashley Moy(Executive Officer, Director)Jason Troutner(Executive Officer, Director)Justin Brooks(Executive Officer, Director)

Climecastclimecast.comin𝕏
Coologicscoologics.com

Coologics develops a drug-free medical device designed to treat vaginal yeast and bacterial infections through controlled cooling technology.

FemTechMedical Devices

Female OB/GYN

CranioSensecraniosense.comin

CranioSense develops IPASS, a non-invasive medical device that measures intracranial pressure using a forehead patch and handheld device, eliminating the need for invasive skull drilling in traumatic brain injury assessment.

HealthtechMedical DevicesBedford, US

Gordon Hirschman(COB & CO-FOUNDER)inRyan Myers(CEO & CO-FOUNDER)inKristian DiMatteo(COO & CO-FOUNDER)in

cystetic Medicinescysteticmedicines.comNov 2020

Cystetic Medicines develops molecular prosthetics to treat cystic fibrosis, specifically targeting the 10% of CF patients who cannot benefit from existing modulator therapies due to little-to-no CFTR protein.

BiotechHealthtechMedical DevicesChampaign, US

PETER W STEELMAN(Director)JONATHAN RAMOS(Director)PETER B. FINN(Executive Officer)MARTIN BURKE, MD., PH.D.(Director)ZHENG SU(Director)Dr. Martin D. Burke(Co-founder)

DeepWalkdeepwalk.comin
EarthSenseearthsense.coin𝕏

EarthSense develops AI and robotics solutions for agriculture to address sustainability and productivity challenges.

AgTechAI & Machine LearningRobotics

Eden Park Illuminationedenpark.comin

Eden Park manufactures wafer-thin Far-UVC 222nm technology panels that continuously disinfect air and surfaces to reduce viruses and bacteria in populated spaces.

CleantechHardwareHealthtechChampaign, US

Cy Herring(Executive Officer, Director)Timothy Gary Kudron(Director)Tom Parkinson(Director)James Garry Eden(Director)Randy Cothers(Executive Officer)William Brewer(Director)

Elion Therapeuticseliontx.comJun 2024

BiotechNew York, US

Jim Flynn(Director)Kieren Marr(Executive Officer, Director)

BoardMartin Heidecker(Director)Jonathan Leff(Director)

Excelsior Sciencesexcelsiorsci.comin

Excelsior Sciences develops automated chemistry technology for small-molecule discovery and manufacturing, targeting pharmaceutical and materials development.

AI & Machine LearningBiotechDeep Tech

Michael Foley(CEO)Jana Jensen(COO)Marty BurkeBartosz Grzybowski

FirstIgnitefirstignite.comin𝕏

FirstIgnite provides AI software that helps universities, hospitals, nonprofits, and foundations identify, engage, and manage partnership opportunities in research funding, philanthropy, and technology licensing.

AI & Machine LearningEnterprise SoftwareSaaS

Chase Bonhag(Founder)inCody Pawlowski(Founder)in

Integrated Dynamicsint-dyn.com

Integrated Dynamics develops high-temperature fermentation technology to produce bio-based chemical intermediates for onshore manufacturing.

Advanced ManufacturingBiotechDeep Tech

Inventablesinventables.com𝕏

Inventables manufactures and sells desktop CNC machines, parts, and accessories for makers, creative professionals, and small manufacturers.

Advanced ManufacturingCreator EconomyHardwareChicago, US

BoardZach Kaplan(Executive Officer, Director)Phil Black(Director)Sue Khim(Director)

KeywiseAIkeywise.tech

KeyWise AI develops Skye, a system that continuously assesses cognitive performance by passively capturing keystroke behavior (not content) as people type on their phones during normal use.

AI & Machine LearningDigital HealthHealthtech

Madison Scientificmadsci.comin

HealthtechChicago, US

Tyler Wanke(Executive Officer, Director)Bermans Iskandar(Director)Joshua Medow(Executive Officer, Director)

BoardJoshua Carson(Director)John Slump(Director)

Mesh++meshplusplus.comin𝕏

Mesh++ manufactures wireless mesh networking hardware with low-loss routing protocols for fast, automatic connections across difficult-to-serve areas.

HardwareIoTChicago, US

Danny Gardner(Founder)

Natrionnatrion.co

EnergyAlbany, US

Alexander S Kosyakov(Executive Officer, Director)Thomas Rouffiac(Cofounder)

BoardManas Gosavi(Director)Terry Howerton(Director)Thomas A Rouffiac(Director)

Network Perceptionnetwork-perception.com

Chicago, US

Ted Greene(Chief Operating Officer)Robin Berthier(Chief Executive Officer, President, & Director)William Sanders(Director)Robert Schultz(Director)

BoardJeff Bocan(Director)Steve Westly(Director)

Ocientocient.comin𝕏

Ocient builds petabyte-scale agentic AI solutions through its OcientAIQ platform for enterprises managing massive datasets.

AI & Machine LearningData & InfrastructureEnterprise SoftwareChicago, US

George Kondiles(Executive Officer)S. Christopher Gladwin(Executive Officer, Director)Kumar Abhijeet(Executive Officer)William McCarthy(Executive Officer)Joseph Jablonski(Executive Officer)

BoardJames Dugan(Director)

Pathlitpathlit.com
Petrichorpetrichortech.comin𝕏

Petrichor provides a digital platform for managing global supply chains and raw material trade.

Enterprise SoftwareLogistics & Supply ChainSaaS

Phi Opticsphioptics.comin𝕏

Phi Optics develops quantitative phase imaging (QPI) technology that upgrades existing microscopes to enable non-invasive, real-time 3D imaging of live cells, tissues, organoids, and small organisms without labels or specimen damage.

AI & Machine LearningDeep TechMedical DevicesChampaign, US

Catalin Chiritescu(Executive Officer, Director, Promoter)Timothy Hoerr(Director)Gabriel Popescu(Executive Officer, Director, Promoter)Jed Taylor(Director)

Photon Queuephotonqueue.comin

Photon Queue develops quantum memory devices using linear optics technology for photon storage.

Deep TechQuantum ComputingSan Francisco, US

Kelsey Ortiz(Co-founder)

Photonicarephotoni.carein𝕏

PhotoniCare develops OtoSight, an FDA-cleared optical coherence tomography device for non-invasive assessment and monitoring of middle ear infections in healthcare facilities.

Deep TechDigital HealthHealthtechMedical DevicesDurham, US

Ryan Shelton(CEO)Cary Vance(Executive Officer, Director)Gary Durack(Member of the Board of Directors)Stephen Boppart(CMO)

BoardPatrick Zeller(Director)Dale Grogan(Director)

PSYONICpsyonic.ioin𝕏

PSYONIC develops advanced, affordable bionic prosthetics, including the Ability Hand, a sensorized prosthetic hand with touch feedback for people with limb differences and amputations.

HealthtechMedical DevicesRoboticsChampaign, US

Aadeel Akhtar(Executive Officer)Patrick Slade(Cofounder)Dr. Aadeel Akhtar(Founder & CEO)

Reconstructreconstructinc.comin
Rectangle Labsrectanglehq.cominDec 2023

Chicago, US

Matthew Salafski(Executive Officer, Director)

Resolv Cryptoresolv.financein𝕏

Resolv provides fraud protection and asset recovery for cryptocurrency holders through recoverable wrapped tokens and community-driven verification.

Crypto & Web3Fintech

RetMapretmapinc.comin

RetMap develops electroretinography (ERG) devices for detecting retinal and eye diseases in human and veterinary medicine.

Deep TechDigital HealthMedical Devices

Revivio Therapeuticsrevivotherapeutics.com
Sakura MedTechsakuramedtech.comin

Sakura MedTech develops a tampon-shaped imaging device as a comfortable alternative to the speculum for cervical cancer screening and gynecological exams.

Digital HealthFemTechMedical DevicesChicago, US

Samara Aerospacesamaraaerospace.comin

Samara Aerospace designs and builds high-performance satellite platforms featuring the Hummingbird satellite bus, which combines pointing stability, agility, and power generation in a compact form for commercial, civil, and national security missions.

Deep TechHardwareSpace TechSuperior, US

Patrick Haddox(Founder)Vedant(Founder)

Senex Biotechnologysenexbio.com

Senex Biotechnology develops small-molecule inhibitors targeting protein regulators of gene expression for cancer treatment, with lead programs in prostate cancer, breast cancer, and leukemia.

BiotechHealthtechMedical Devices

Serionixcolorfil.comMar 2024

Urbana, US

James Langer(Executive Officer)

ShareThissharethis.com𝕏

ShareThis collects and analyzes consumer behavioral data from over three million global websites to provide insights, targeting, activation, and data enrichment services.

AdTechData & InfrastructureMarketing TechSaaSPalo Alto, US

Dana C. Hayes, Jr.(Chief Executive Officer)Myha Trieu(Chief People Officer)Chad Burns(Chief Financial Officer)Huanjin Chen(Chief Technology Officer)Michael Gorman(Chief Product Officer)Paul Lentz(Executive Officer)

Siloam Visionsiloamvision.comin𝕏

Siloam Vision develops medical imaging and software solutions for eye care, with initial focus on retinopathy of prematurity (ROP) in premature infants.

AI & Machine LearningHealthtechMedical DevicesPortland, US

John Peter Campbell(Executive Officer, Director)Tong Sun(Executive Officer)Robison Vernon Paul Chan(Executive Officer)Karyn Jonas(Executive Officer)Dr. Pete Campbell(Founder)Dr. Paul Chan(Founder)

Skyryseskyryse.comin𝕏

Skyryse develops aircraft control systems and software for helicopters and aircraft, offering simplified pilot interfaces, autonomous capabilities, and emergency management features.

Defense TechHardwareRoboticsEl Segundo, US

Mark Groden(Founder)in

Tandemntandemn.com
Tiesta TEAtiestatea.com

Chicago, US

Joseph Nogal(Director)Brad LaConte(Director)Daniel Klein(Executive Officer, Director, Promoter)Adam Harris(Director, Promoter)Alex Sosnov(Executive Officer)Patrick Tannous(Executive Officer, Director, Promoter)

Top Tier Lessonstoptierlessons.com
Vanquish Oncologyvanquishoncology.com

BiotechChampaign, US

Paul Hergenrother(Executive Officer, Director)Ted Tarasow(Executive Officer, Director)Ron Way(Director)Billie Jo Herberger(Director)Judd Heberger(Director)

VedaBiovedabio.comin𝕏

VedaBio develops a molecular detection platform using CRISPR technology that enables rapid, accurate detection of multiple biological targets without the need for amplification.

AI & Machine LearningBiotechDeep TechHealthtechMedical DevicesSan Diego, US

Anurup Ganguli(Founder)inFred(President and CEO)Frédéric Sweeney(President and Chief Executive Officer)Maurice Exner(Chief Operating Officer)

Worktrace Aiworktrace.aiin

Worktrace enables teams to build and deploy AI agents with zero setup required.

AI & Machine LearningEnterprise Software

Exits · 1

IPOs and acquisitions across the tracked portfolio

Actuate TherapeuticsNASDAQ: ACTU

Portfolio news

latest coverage across their companies

Frequently asked questions

What stage does Illinois Ventures invest at?
Illinois Ventures invests at the Pre-Seed, Seed, Series A, Late Stage stages.
What sectors does Illinois Ventures focus on?
Illinois Ventures focuses on Biotech, Consumer, Data & Infrastructure, Deep Tech, Energy, Enterprise Software, Hardware, Medical Devices, New Materials, SaaS, Semiconductors.
Where is Illinois Ventures located?
Illinois Ventures is headquartered in Champaign, US.

Media · Podcasts & interviews

featuring the team

Nancy Sullivan, CEO and Senior Managing Director, Illinois VENTURES

InvestMidwest Venture Capital (Forum) · Nancy Sullivan

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