WRF Capital
Corporate VCSeattle · Pre-Seed–Series B · 21 people tracked
Find your way into WRF Capital
1,712 people in our graph share verified history with the WRF Capital team — schools, employers, funds. One of them is your warm intro.
Investment thesis
WRF Capital invests roughly $5 million annually in Washington-based startups, focusing on spinouts from state nonprofit research institutions such as UW, WSU, Fred Hutch and ISB. It backs pre-seed through Series A companies across life sciences and enabling technologies, with initial checks of $100,000 to $2 million and reserves for follow-ons. Often the first money in, the firm partners with angels and VCs across rounds and can lead investments, syndicating with value-adding firms. It emphasizes rigorous due diligence and selective investing to help commercialize new technologies developed in Washington.
Source: firm website, verified Aug 3, 2026.
Team · 21 people
from the firm's website & curatedWhat they invest in
from 11 of 14 portfolio companiesBiotech ×7Deep Tech ×2EdTech ×2Healthtech ×2AgTech ×1AI & Machine Learning ×1Digital Health ×1Medical Devices ×1
HQs:United States×11
Investments · 14 tracked
founders shown can be your intro pathBy year:2026 · 12024 · 12021 · 12018 · 12015 · 15 dated
2Morrow provides evidence-based digital wellness programs delivered through a smartphone and web app, using Acceptance and Commitment Therapy principles to help people quit tobacco, manage stress, and change health behaviors.
Digital HealthMental HealthWellness & FitnessKirkland, US
Jo Masterson(Executive Officer, Director)inBrandon Masterson(Executive Officer)in
BoardJohn Koster(Director)Eric Larsen(Director)in
Co-investorsPortland Seed FundAlliance of Angels
Accipiter Biosciences uses computational protein design to develop de novo, single-agent protein therapies that engage multiple cell-surface receptors at once, functioning as agonists.
AI & Machine LearningBiotechDeep TechSeattle, US
Matthew Bick(Executive Officer, Director, Promoter)inJavier Castellanos(Executive Officer, Director, Promoter)inHector De Jesus Rincon Arano(Executive Officer, Promoter)Heather Redman(Director)Randall Schatzman(Director)William Canestaro(Executive Officer)in
Co-investorsCreative Destruction Lab (CDL)Argonautic VenturesColumbus Venture PartnersPack Ventures
Seattle, US
JACOB O. WOBBROCK(Executive Officer)inWILLIAM T. COLLERAN(Executive Officer, Director)ANDREW KO(Executive Officer)
BoardWILLIAM MCALEER(Director)inMARK UPSON(Director)MICHAEL FRIDGEN(Director)
Co-investorsCowles VenturesThe W FundVoyager Capital
BiotechSeattle, US
Rahul Shendure(Executive Officer, Director, Promoter)inMatthew Snyder(Director)
Co-investorsThe W Fund
Automates complex call center operations; acquired by Sagility Health.
Co-investorsAllen Institute for AI (AI2) IncubatorFlare Capital PartnersAI GrantRadical Ventures
Fred Hutch is a cancer research institute that develops biomarkers, therapies, and stem cell products for research and clinical use, and provides data infrastructure and funding to commercialize discoveries into treatments and spinout companies.
BiotechHealthtechMedical DevicesSeattle, US
Nexgenia develops proprietary stimuli-responsive polymer-based reagents for molecular and cellular selection, diagnostics, and immunoassays.
BiotechDeep TechNew MaterialsSeattle, US
Ron Myers(Executive Officer, Director)
BoardSteven Gillis(Director)Charles P. Waite(Director)Martin Simonetti(Director)Stewart Parker(Director)David Urdal(Director)
Co-investorsThe W FundAlliance of Angels
Proniras Corporation is a clinical-stage biotechnology company developing novel small-molecule therapeutics for substance use disorders and specialty central nervous system (CNS) conditions, including treatments for opioid withdrawal and seizure disorders.
BiotechHealthtechSeattle, US
CHRISTOPHER TOOMBS(Executive Officer)inLINDSAY RAYLE(Executive Officer, Promoter)M. Johnston Erwin(Director)David Schubert(Executive Officer, Promoter)
BoardSTEVEN GILLIS(Director)inThong Le(Executive Officer, Director, Promoter)
Co-investorsACCELERATOR LIFE SCIENCE PARTNERSARCH Venture Partners
Biopharma company developing non-immunosuppressive drugs for autoimmune diseases.
James Posada, Ph.D.(Founder)in
Co-investorsNew Science VenturesEaston Capital
University of Washington is a public research institution offering undergraduate, graduate, and professional education across multiple campuses and disciplines including engineering, computer science, business, medicine, law, and environmental studies.
EdTechSeattle, US
Co-investorsShumo Chu
Washington State University is a public research institution operating six campuses across Washington state and online, offering academic programs in fields including health sciences, STEM, business, engineering, and social sciences.
EdTechPullman, US
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
Portfolio news
latest coverage across their companiesUW · madison.com · Aug 19, 2026

WSU · kpq.com · Nov 19, 2025
Frequently asked questions
- How many investments has WRF Capital made?
- WRF Capital has 14 tracked investments, including 1 dated in the last 24 months.
- What stage does WRF Capital invest at?
- WRF Capital invests at the Pre-Seed, Seed, Series A, Series B stages.
- What is WRF Capital's typical check size?
- WRF Capital typically writes checks of $100K – $2M.
- What sectors does WRF Capital focus on?
- WRF Capital focuses on Biotech, Consumer, Data & Infrastructure, Deep Tech, Digital Health, Enterprise Software, Hardware, Healthtech, Medical Devices, New Materials, SaaS.
- Where is WRF Capital located?
- WRF Capital is headquartered in Seattle, US.
- Does WRF Capital lead rounds?
- Yes, WRF Capital leads investment rounds.
Co-investors · 1
Early-stage venture capital firm focused on digital health innovations including digital diagnostics, digital therapeutics, and tech-enabled services. Based in Boston and Philadelphia with deep clinical expertise and experience building and scaling healthcare ventures.
Firms observed investing alongside WRF Capital, from public investor directories. Shared companies are the overlap with WRF Capital's recorded portfolio.
Similar investors
DCVC (Data Collective) is a deep tech venture capital firm that backs entrepreneurs using computational approaches to solve large-scale real-world problems across many industries.
Karista is a French venture capital firm that invests in tech and early-stage companies, frequently leading funding rounds and supporting founders through strategic guidance and board involvement.
Everywhere Ventures is an early-stage venture firm, backed by a community of founders and operators as LPs, that writes early checks (including pre-seed) into startups across many sectors and geographies.
Khosla Ventures is a venture capital firm founded by Vinod Khosla.
OMERS Ventures is a venture capital firm that invests in founders globally, with investment teams based in New York, Palo Alto, and Toronto.














































