Foresite Capital — Full Portfolio

BiotechHayward, US

Roger M. Perlmutter(Executive Officer, Director)Adam Goulburn(Director)

BoardJoshua Wolfe(Director)Dror Berman(Director)Leon Chen(Director)

Board seatJames Tananbaum· per SEC Form D

BiotechCambridge, US

Alan Ezekowitz(Director)James Collins(Director)Mark Levin(Director)Robert Gould(Executive Officer, Director)James Geraghty(Director)

Board seatJames Tananbaum· per SEC Form D

Natera develops genetic tests and diagnostics using cell-free DNA technology to detect diseases including cancers, genetic disorders, and transplant-related conditions.

BiotechDigital HealthHealthtechMedical Devices<UNKNOWN>

Matthew Rabinowitz(Co-founder & Executive Chairman)

Next-generation genetic sequencing using microfluidics for sequencing and molecular diagnostics

Aclaris develops investigational monoclonal antibodies and small-molecule inhibitors targeting immune pathways for the treatment of atopic, autoimmune, and respiratory diseases.

BiotechHealthtechMedical DevicesWayne, US

Neal Walker(Executive Officer, Director)Joseph Monahan(Executive Officer)Hugh Davis(Executive Officer, Director)James Loerop(Executive Officer)Kevin Balthaser(Executive Officer)Kamil Ali-Jackson(Executive Officer)

Adaptive Biotechnologies decodes the genetic patterns of the adaptive immune system to develop clinical products for diagnosing and treating disease.

BiotechDigital HealthHealthtechMedical DevicesSeattle, US

Arnold Levine(Director)Chad Robins(Executive Officer, Director)Andris Zoltners(Director)Tom Willis(Director)Kathleen Determann(Executive Officer)Peter Neupert(Director)

BiotechMenlo Park, US

Nathan Hubbard(Executive Officer)Aya Jakobovits(Executive Officer, Director)Jonathan Silverstein(Director)Carl Gordon(Director)Florent Gros(Director)Erez Chimovits(Director)

Alector develops therapies targeting neurodegenerative diseases including Alzheimer's, frontotemporal dementia, and Parkinson's disease through protein removal, replacement, and immune cell restoration.

AI & Machine LearningBiotechHealthtechLongevityMedical DevicesSan Francisco, US

Arnon Rosenthal(Ph.D.)Carl Gordon(Director)Tillman Gerngross(Director)Terry McGuire(Director)

Allogene Therapeutics develops allogeneic CAR T cell therapies (AlloCAR T) for blood cancers, solid tumors, and autoimmune diseases, using off-the-shelf manufactured cell products rather than patient-derived autologous approaches.

BiotechHealthtechMedical Devices

ROBERT ABRAHAM(Director)OWEN WITTE(Director)DAVID BONDERMAN(Director)TODD SISITSKY(Director)JOSHUA A. KAZAM(Executive Officer, Director)DAVID M. TANEN(Executive Officer)

Alumis is a clinical-stage biopharmaceutical company developing a late-stage portfolio of targeted oral therapies for immune-mediated diseases such as plaque psoriasis.

AI & Machine LearningBiotechDigital Health

BiotechWarminster, US

Andrew Cheng(Director)Eric Venker(Director)William H. Collier(President and Chief Executive Officer)Gaston Picchio(Chief Development Officer)Michael J. McElhaugh(Chief Business Officer)Frank Torti(Chairman)

BiotechFremont, US

Annalisa Jenkins(Director)Mark Kaufmann(Executive Officer)Elizabeth Grammer(Executive Officer)Richard Rodgers(Director)Gordon Ringold(Director)Peter G. Schultz(Director)

Beam Therapeutics develops gene-editing medicines, particularly base editors and precision genome editing technologies, to create lifelong cures for patients with serious genetic diseases.

BiotechDeep TechMedical DevicesCambridge, US

David R. Liu(Founder and Inventor)J. Keith Joung(Founder and Inventor)Feng Zhang(Founder and Inventor)CAROLE HO(Director)John Evans(Executive Officer, Director)MARK FISHMAN(Director)

BiotechBeijing

Chunhua Wang(Chief Operating Officer)Wei Gao(General Counsel)Alexander Y. Wu(Director)Zhenbo Su(Director)Hai Huang(Global Chief Commercial Officer)Kun Qian(Global Controller)

BiotechHampton, US

Herbert J. Conrad(Director)Anthony S. Marucci(Executive Officer, Director)Karen Shoos(Director)Richard van den Broek(Director)Larry Ellberger(Director)Avery W. Catlin(Executive Officer)

Cambridge, US

HealthtechBurlingame, US

Leiv Lea(Executive Officer)Elisha (Terry) P. Gould(Director)Peter Moldt(Director)Peter Thompson(Director)Richard A. Miller(Executive Officer, Director)

BiotechSan Diego, US

YunFei Zhu(Executive Officer)Steve Kaldor(Director)Mason Freeman(Director)Wendell Wierenga(Director)Richard Scott Struthers(Executive Officer, Director)Mahendra Shah(Director)

Denali Therapeutics develops therapeutics for neurodegenerative diseases.

BiotechHealthtechMedical DevicesSan Francisco, US

Carole Ho(Executive Officer)Vicki L. Sato(Director)Nancy A. Thornberry(Director)Peter S. Klein(Director)Marc Tessier-Lavigne(Director)Jay T. Flatley(Director)

Boulder, US

Kevin Koch(Executive Officer, Director)Peter Thompson(Director)Kenneth Harrison(Director)Jonathan Root(Director)Alan Russell(Director)

GRAIL develops the Galleri blood test for multi-cancer early detection using next-generation sequencing and machine learning to screen for multiple deadly cancer types before symptoms appear.

AI & Machine LearningBiotechHealthtechMedical DevicesMenlo Park, US

Joshua Ofman, MD, MSHS(Chief Executive Officer)Aaron Freidin(Executive Officer)Sarah Krevans(Director)Gregory Summe(Director)Josh Ofman(Executive Officer)Steve Mizell(Director)

Hinge Health builds a digital healthcare platform designed to help individuals manage musculoskeletal health and related conditions.

Digital HealthHealthtechMedical DevicesWellness & FitnessSan Francisco, US

Gabriel Mecklenburg(Executive Officer, Director)Daniel Perez(Executive Officer, Director)

Insmed is a biopharmaceutical company that provides grants and charitable funding to support healthcare provider education and patient care initiatives focused on nontuberculous mycobacterial lung disease, non-cystic fibrosis bronchiectasis, and other serious lung diseases.

BiotechDigital HealthHealthtechMedical Devices<UNKNOWN>, US

BiotechCambridge, US

Nessan Bermingham(Executive Officer, Director)Jose Rivera(Executive Officer)Carl Gordon(Director)Jean-Francois Formela(Director)John Leonard(Executive Officer, Director)Rachel Haurwitz(Director)

Antibodies to neutralize SARS-CoV-2 and related coronaviruses (NASDAQ: IVVD).

BiotechNewton, US

Peter Honig(Director)Barry E. Greene(Director)Stuart Poulton(Executive Officer)Michael Mano(Executive Officer)Reshma Rangwala(Executive Officer)Richard Paulson(Executive Officer, Director)

BiotechLexington, US

Jasbir S. Seehra(Executive Officer, Director)Julius Knowles(Director)Alon Lazarus(Director)Ohad Hammer(Director)Ran Nussbaum(Director)

Kura Oncology is a company in the oncology/medtech sector that provides grant support for independent medical education programs designed to enhance healthcare professionals' ability to diagnose and treat patients in Kura Oncology's therapeutic areas of interest.

BiotechDigital HealthMedical DevicesLa Jolla, US

HEIDI HENSON(Executive Officer)TROY WILSON(Executive Officer, Director)ANNETTE NORTH(Executive Officer)PINGDA REN(Executive Officer)YI LIU(Executive Officer)ANTONIO GUALBERTO(Executive Officer)

BiotechFort Washington, US

Fred Craves(Director)Rebecca Taub(Executive Officer, Director)Lionel Carnot(Director)

San Francisco, US

David Goeddel(Director)Mark Goldsmith(Director)Arthur T. Sands(Executive Officer, Director)Timothy Kutzkey(Executive Officer, Director)

Creating next generation precision medicines for patients with cancer and inflammatory diseases by targeting key signaling nodes.

BiotechCambridge, US

Valerie Odegard(Director)Jill Carroll(Director)Carl Gordon(Director)Jeffrey Leiden(Director)Charles Baum(Director)Gary D Glick(Executive Officer, Director)

BiotechSan Francisco, US

Cyrus L. Harmon, Ph.D.(Director)David C. Myles, Ph.D.(Executive Officer)Sean Bohen, M.D., Ph.D.(Executive Officer, Director)Naseem Zojwalla, M.D.(Executive Officer)Shane Kovacs(Executive Officer)David Myles(Executive Officer)

Improving patients' lives by accelerating development and commercialization of medicines that matter.

BiotechCambridge, US

Thomas Catinazzo(Executive Officer)Peter Rahmer(Executive Officer)Sekar Kathiresan(Director)Douglas S. Ingram(Director)Sanjiv K. Patel(Executive Officer, Director)Mark Murcko(Director)

BiotechRedwood City, US

Laurence Lasky(Director)Alexis Borisy(Director)Margaret Horn(Executive Officer)Michael Bonney(Director)Mark A. Goldsmith(Executive Officer, Director)Elizabeth Anderson(Director)

BiotechBoston, US

Edward T. Mathers(Director)David J. McGirr(Director)Jonathan Silverstein(Director)Keith Gottesdiener(Executive Officer, Director)David P. Meeker, M.D.(Director)Neil Exter(Director)

Seaport Therapeutics develops therapeutics and medicines.

BiotechMental HealthBoston, US

Daphne Zohar(Founder, CEO and Board Member)Michael Chen(Executive Officer)Lana Gladstein(Executive Officer)Antony Loebel(Executive Officer)Eric Green(Executive Officer)

BoardJames I. Healy(Director)

BiotechLondon

James Ede-Golightly(Director)Alistair Gray(Director)Craig Tooman(Executive Officer)Dave Lemus(Director)Giles Campion(Executive Officer)Romano Steven(Director)

BiotechCharlestown, US

Lynne Sullivan(Director)Adam Koppel(Director)Stephen DiPalma(Executive Officer)Martin Freed(Director)Alexander (Bo) Cumbo(Executive Officer, Director)Paul Herizch(Executive Officer)

Tango Therapeutics develops genetically targeted medicines using synthetic lethality principles to treat specific tumors.

BiotechBoston, US

John Ketchum(Director)Barbara Weber(Executive Officer, Director)Malte Peters(Director)Kanishka Pothula(Director)Lesley Ann Calhoun(Director)Mace Rothenberg(Director)

Verastem Oncology is a biopharmaceutical company that discovers and develops drugs to treat cancer patients.

BiotechMedical DevicesNeedham, US

Robert WeinbergTIMOTHY BARBERICH(Director)ALISON LAWTON(Director)ERIC ROWINSKY(Director)BRUCE WENDEL(Director)GINA CONSYLMAN(Director)

Singapore

Remix Therapeutics develops RNA reprogramming technology to treat various diseases and disorders.

AI & Machine LearningBiotechWatertown, US

Peter Smith, PhD(Co-Founder, President and Chief Executive Officer)Peter Smith(Co-Founder, President and Chief Executive Officer)Robert Gagnon(Executive Officer)Matthew Patterson(Director)Kevin Bitterman(Director)Jeff Goater(Director)

Board seatMichael Rome· per SEC Form D

bit.bio is a synthetic biology company that engineers human induced pluripotent stem cells into defined cell types for research, drug discovery, and cell therapy applications.

BiotechDeep TechHealthtechMedical Devices

Dr Mark Kotter(Founder)Przemek Obloj(CEO)

Cerevance is a clinical-stage drug discovery and development company developing non-dopaminergic, orally-delivered therapies for brain and central nervous system disorders, including Parkinson's disease, schizophrenia, Alzheimer's disease, and ALS.

BiotechDeep TechHealthtech

Craig Thompson(Chief Executive Officer)Sagar Vaidya(Chief Medical Officer)Carrie Ann Cook(Chief Business Officer)

HealthVerity operates a healthcare and consumer data ecosystem that enables HIPAA-compliant synchronization and exchange of real-world data across pharma, payers, and government agencies.

Data & InfrastructureEnterprise SoftwareHealthtechPhiladelphia, US

Andrew Kress(Co-Founder and CEO)Andrew Goldberg(Co-Founder and COO)Rachel Winokur(Director)

BoardMichael Greeley(Director)

HealthtechSan Mateo, US

Joonkyoo (Anthony) Yun(Director)Stacey D. Seltzer(Director)James Tananbaum(Director)Victor Colunga(Executive Officer)Bryan L. Walser(Director)Stephen G. Dilly, Jr.(Executive Officer, Director)

Board seatJames Tananbaum· per SEC Form D · $80M raise · filed Mar 2015

HealthtechSan Francisco, US

James Tananbaum(Director)June Lee(Executive Officer, Director)Vikram Bajaj(Director)

Board seatMichael RomeVikram Bajaj· per SEC Form D · $60M raise · filed Mar 2021

HealthtechSouth San Francisco, US

Zachary Sweeney(Executive Officer, Director)Vikram Bajaj(Director)James Tananbaum(Director)

Board seatJames TananbaumVikram Bajaj· per SEC Form D · $50M raise · filed Nov 2021

BiotechSan Diego, US

Stephen W. Kaldor(Executive Officer, Director, Promoter)Eric Murphy(Executive Officer, Director)Bret Zbar(Director)Carl Gordon(Director)Michael Rome(Director)

Board seatMichael Rome· per SEC Form D

Pardes Biosciences develops oral medications designed to treat and prevent viral infections, including COVID-19.

BiotechHealthtechSan Francisco, US

Uri Lopatin(Founder/CEO)inUri A. Loptain(Executive Officer, Director)Mark Aueurbach(Director)Michael D. Varney(Director)J. Jay Lobell(Director)Heidi Henson(Executive Officer)

Board seatJames B. Tananbaum· per SEC Form D

BiotechWoburn, US

Feng Xuan(Executive Officer, Director)Peng Yin(Director)Wen Chan(Director)John Wu(Executive Officer)Michael Natan(Executive Officer, Director)

BoardDavid Singer(Director)

Board seatVikram Bajaj· per SEC Form D

BiotechPhiladelphia, US

David Brand(Executive Officer, Director)Richard Kollender(Director)Martin Edwards(Director)Eric Bednarski(Director)Gregory Lumpkin(Executive Officer)Derek Ferguson(Director)

Board seatJames Tananbaum· per SEC Form D · $2M raise · filed Feb 2016

BiotechCambridge, US

Iain Dukes(Executive Officer, Director)William C. Shakespeare(Director)Michael Rome(Director)Carl Gordon(Director)

Board seatMichael Rome· per SEC Form D

Biotech

James A. Geraghty(Director)Joanne T. Beck(Director)Bobby Gaspar(Executive Officer, Director)Marc Dunoyer(Director)Steven M. Altschuler(Director)Frank E. Thomas(Executive Officer)

A pharmaceutical company that develops medicines and vaccines for patients globally.

BiotechHealthtechMedical Devices

BiotechBerkeley, US

Frank McCormick(Director)Gerald David Chan(Director)Thomas Dubensky(Executive Officer)Dirk G. Brockstedt(Executive Officer)Ross Haghighat(Director)William Greenman(Director)

BiotechNorth Cambridge, US

Richard Malley(Director)Robert More(Director)Frances Heller(Director)Kamran Tavangar(Executive Officer)George Siber(Director)Steven Brugger(Executive Officer, Director)

Akero develops engineered protein therapies for metabolic diseases, particularly MASH (metabolic dysfunction-associated steatohepatitis) and other conditions with high unmet medical need.

BiotechHealthtechMedical Devices

Ascendis Pharma is a biopharmaceutical company developing therapies for hormone-related disorders and rare diseases.

BiotechHealthtechMedical DevicesDenmark, DK

Jan Møller Mikkelsen(Founder, President and Chief Executive Officer)

CandidRx develops T-cell engager antibodies to treat autoimmune diseases by redirecting T-cells to eliminate autoreactive B-cells.

BiotechHealthtechSan Diego, US

Ken Song(Chairman, President and CEO)Kenneth Song, M.D.(Executive Officer, Director)Arvind Kush(Executive Officer)Timothy Lu, M.D.(Executive Officer)Bernie Huyghe, Ph.D.(Executive Officer)

BoardJeffrey Tong, Ph.D.(Director)

Color Health operates a nationwide virtual cancer clinic delivering oncologist-led care, screening, and treatment management for employer, union, health plan, and public sector populations.

AI & Machine LearningDigital HealthHealthtechSan Francisco, US

Othman Laraki(CEO)

BiotechNewark, US

Harold Van Wart, Ph. D.(Executive Officer, Director)Carl Goldfischer, M.D.(Director)Pol Boudes(Executive Officer)Kurt von Emster(Director)Hari Kumar, Ph.D.(Director)Charles A. McWherter, Ph. D.(Executive Officer)

DELFI Diagnostics develops FirstLook Lung, a blood-based laboratory test for lung cancer screening that identifies genome-wide alterations in individuals eligible for screening.

AI & Machine LearningBiotechDigital HealthHealthtechMedical DevicesBaltimore, US

Peter Bach(Executive Officer)Elizabeth Homans(Director)Rishi Gupta(Director)Justin Kao(Director)Jennifer Buechel(Executive Officer)Victor Velculescu(Executive Officer, Director, Promoter)

HealthtechMenlo Park, US

LUIS PENA(Executive Officer)CHRISTOPHER GRIFFITH(Executive Officer)KATHLEEN SEBELIUS(Director)DAVID E. COHEN(Director)FRED CRAVES(Director)THOMAS G. WIGGANS(Executive Officer, Director)

DNAnexus is a cloud platform for precision health research that enables pharmaceutical, biotech, and academic organizations to process and analyze genomic and multi-omics data at scale.

BiotechCloud ComputingData & InfrastructureMountain View, US

HANNES SMARASON(Director)Richard Daly(Executive Officer, Director)MICHAEL GOLDBERG(Director)GEOFF DUYK(Director)STEPHEN THAU(Executive Officer)NATHANIEL GOLDHABER(Director)

BiotechSan Francisco, US

RAJEEV SHAH(Director)JONATHAN FOX(Executive Officer)UMA SINHA(Executive Officer)HOYOUNG HUH(Director)NEIL KUMAR(Executive Officer, Director)ERIC AGUIAR(Director)

Element Biosciences develops biological analysis platforms and DNA sequencing tools for scientists and research institutions.

BiotechDeep TechHardwareMedical Devices

Everlyhealth operates an at-home laboratory testing platform that enables consumers to monitor their health through biomarker analysis across multiple categories including daily health, digestive health, sexual health, and hormone health, with optional virtual care consultations.

ConsumerDigital HealthHealthtech

Everlywell offers at-home lab testing kits and virtual healthcare services across multiple wellness categories including daily health screening, digestive analysis, sexual health testing, and hormone monitoring.

Digital HealthHealthtechWellness & Fitness

Julia Cheek(Founder & CEO)

Fabric Genomics provides an AI-based platform for next-generation sequencing (NGS) analysis, interpretation, and clinical reporting for rare disease, hereditary risk, and cancer testing.

AI & Machine LearningBiotechDigital HealthHealthtechMedical Devices

Martin Reese(Co-Founder, President, and CEO)Erwin Frise(Vice President of Technology and Data Science)

FOLX is a digital healthcare platform designed for LGBTQIA+ adults, providing inclusive and affirming medical care.

Digital HealthHealthtechBoston, US

A.G. Breitenstein(Founder)Lynne Chou O'Keefe(Director)Lena Ballantine(Executive Officer)Liana M Guzman Weis(Executive Officer, Director)Morgan Cheatham(Director)Lee Shapiro(Director)

BiotechCambridge, US

Geoff McDonoughy(Executive Officer, Director)Glenn Goddard(Executive Officer)Jason Rhodes(Director)Anthony Quinn(Director)Gustav Christensen(Director)Donald Nicholson(Director)

Sebastian G. Schneeweiss(Director)William Geary(Director)Jeremy Rassen(Executive Officer, Director)

BiotechBoulder, US

Michael Graige(Executive Officer)John R. Stuelpnagel(Director)Ron McGrath(Executive Officer)Sri Kosaraju(Executive Officer, Director)Roger Wyse(Director)Dianna L. DeVore(Executive Officer)

insitro is a drug discovery and development company that uses machine learning and cellular data to identify therapeutic insights and accelerate the creation of new medicines.

AI & Machine LearningBiotechSouth San Francisco, US

Daphne Koller(CEO & Founder)Robert Nelsen(Director)Vijay Pande(Director)Duane Valz(General Counsel)Mary Rozenman(Chief Financial Officer)

Biopharmaceutical company developing innovative therapies for chronic diseases using proprietary drug delivery systems.

BiotechBoston, US

James Ahlers(Executive Officer)Irwin Scher(Director)John Yee(Executive Officer)Sunita Zalani(Executive Officer)Raymond T. Keane(Executive Officer)Emad Rizk(Director)

BiotechMorrisville, US

Neelaksh Varshney(Director)Michele Stone(Executive Officer)Ilan Oren(Director)Saira Ramasastry(Director)Ryan Gallagher(Director)Keith Manchester(Director)

BiotechThousand Oaks, US

Nima Farzan(Executive Officer, Director)Tim Lugo(Executive Officer)

BoardBeth Seidenberg(Director)Jim Tananbaum(Director)Deborah Palestrant(Director)Kevin Raidy(Director)

Lucira Health manufactures portable diagnostic devices that connect to smartphones to test bodily fluids for infectious diseases, enabling rapid results outside of clinical settings.

BiotechHealthtechMedical DevicesEmeryville, US

Debkishore Mitra(Founder)inSteve Tablak(Director)Erik T. Engelson(Executive Officer, Director)Justin Butler(Director)Tuff Yen(Director)John R. Waldeisen(Director)

Mammoth Bio develops technology to read and write the code of life, operating in the biotechnology sector.

BiotechDeep TechMedical DevicesBrisbane, US

Jennifer Doudna(Founder)inTrevor Martin(Co-founder, Chief Executive Officer)Janice Chen(Co-founder, Chief Scientific Officer & President, Research)Lucas Harrington(Co-founder)inUrshit Parikh(Director)Ashley Tehranchi(Executive Officer, Director)

Mirvie develops an RNA-based platform for early detection of pregnancy complications, enabling proactive intervention before complications become critical.

BiotechFemTechHealthtechSouth San Francisco, US

Lisa Iverson(Director)Naomi Kelman(Director)inManeesh Jain(Executive Officer, Director, Promoter)inStanley Lapidus(Director)inStephen Quake(Director)

BoardUrsheet Parikh(Director)

BiotechSouth San Francisco, US

Kevin Starr(Director)Charles Homcy(Director)Mark Perry(Director)Katherine Bowdish(Director)Tassos Anastasios Gianakakos(Executive Officer, Director)

BiotechSouth San Francisco, US

McHenry T. Tichenor, Jr.(Director)William J. Rieflin(Executive Officer, Director)Peter Svennilson(Director)Jin-Long Chen(Executive Officer, Director)Mark Leschly(Director)David V. Goeddel(Director)

HealthtechYardley, US

Per Djupesland(Executive Officer, Director)Michele Janis(Executive Officer)Larry Pickering(Director)Patrick O'Neill(Director)Peter Miller(Executive Officer, Director)Klaas De Boer(Director)

Pleno develops an instrument platform for genomic testing that enables AI-driven precision medicine through faster, lower-cost multiomics analysis.

AI & Machine LearningBiotechMedical Devices

Redesign Health is a venture capital and applied technology platform that builds and invests in next-generation healthcare companies using AI-native strategies.

AI & Machine LearningDigital HealthHealthtech