Toronto · Pre-Seed–Seed · 155 people tracked
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Investment thesis
CDL is a nonprofit, university-based startup program (originating at the Rotman School of Management, University of Toronto) whose mission is to enhance the commercialization of science for the betterment of humankind. Its central thesis is that poor commercialization of scientific innovation stems from a failure in the 'market for judgment' — experienced entrepreneurs help novice founders set and prioritize objectives to derisk their businesses. CDL operates specialized streams (AI/machine learning, quantum, space, climate, fintech, blockchain) across multiple global sites, combining experiential business education with venture support. It measures success by equity value created, reporting over CAD$51B generated by participating companies.
Source: firm website, verified Aug 17, 2026.
Team · 155 people
from the firm's website & curated & public directoriesFounder mafia
The Creative Destruction Lab (CDL) mafia →7 people who came through Creative Destruction Lab (CDL) went on to found or lead other companies.
What they invest in
from 196 of 446 portfolio companiesAI & Machine Learning ×75Deep Tech ×55Cleantech ×47Climate Tech ×44Healthtech ×39Hardware ×37Biotech ×35Medical Devices ×30
HQs:United States×57Canada×51United Kingdom×8Germany×5France×4Austria×2
Who they back
founder profiles across 131 portfolio companiesFounding team size:solo founder×462 founders×523 founders×174+ founders×16
Where their founders studiedfrom 148 founders with education data
University of California, Berkeley ×12University of Toronto ×11University of Waterloo ×10University of Cambridge ×8McGill University ×7Stanford University ×5University of Oxford ×4University of Pennsylvania ×4
What their founders studiedfrom 160 founders with field-of-study data
Engineering ×79Business & Management ×20Computer Science ×20Life Sciences ×20Mathematics & Statistics ×14Physics ×14Chemistry ×5Finance & Accounting ×5
Where their founders worked beforefrom 160 founders with career history
Stanford University ×5Microsoft ×4SpaceX ×4Berkeley Lab ×3Caltech ×3Danfoss ×3Google ×3McKinsey & Company ×3
Accelerator rootsportfolio companies that came through a program
Y Combinator ×14Techstars ×13Entrepreneur First ×9500 Global ×2
64 founders hold a PhD · 18 hold an MBA (of 169 with degree data)
Portfolio companies · 446 tracked
alumni founders can tell you what the program is really likeBy year:2026 · 22025 · 22024 · 32023 · 22022 · 52021 · 52020 · 12019 · 12017 · 12012 · 123 dated
Comcast operates two main businesses: Connectivity & Platforms, which provides residential broadband, video, and wireless services plus business telecommunications solutions; and Content & Experiences, which includes cable television networks, streaming services, film and television studios, and theme parks.
Ralph J. RobertsJulian A. Brodsky
2S Water manufactures AquaValid, a real-time water analyzer that continuously measures dissolved metals in process water using optical-emission spectroscopy technology.
CleantechClimate TechHardwareIoT
Co-investorsBURNT ISLAND VENTURESForesight CanadaStartup TNT
4D Surgical develops imaging technology for image-guided surgical procedures.
HealthtechMedical Devices
Co-investorsAlso CapitalMythos Ventures Management, LlcInflect Health
4pi Lab develops remote sensing satellites to detect, monitor, and respond to wildfires and their emissions for climate change mitigation.
AI & Machine LearningClimate TechDeep TechSpace Tech
Stephen Achal(Chief Executive Officer, Chief Strategy Officer)inVictor Taylor(Chief Technology Officer)
Co-investorsSeraphim Space
6Degrees is an Israel-based startup that develops digital accessibility solutions to help people with physical challenges gain independence, improve communication, and increase employability through enhanced digital access.
Digital HealthHardwareHealthtechImpact & Social GoodIoTMedical DevicesIsrael, IL
Aryeh Katz(Co-founder)inMiri Berger(Co-founder)in
Co-investorsIceland Venture StudioUnknown Group
AAZZUR provides a platform for creating and integrating financial services, including neo-banking solutions for startups, embedded finance for corporates, and banking-as-a-service infrastructure.
Cloud ComputingEnterprise SoftwareFintechSaaSBerlin, DE
Philipp Buschmann(CEO)inMartin Damaske(COO/CFO)inLaura Kerturke(Head of Product)inRichard Unger(CTO)in
Co-investors1818 Venture CapitalAlumni VenturesAngels Denastorya.vcBasecamp FundGreat Stuff Ventures+3 more
Accelerate Wind develops edge-of-roof wind turbine technology for commercial and industrial customers globally, enabling local energy generation by harnessing wind channeled by building structures.
Advanced ManufacturingCleantechClimate TechEnergyHardwareSt. Louis, US
Erika Boeing(Founder & CEO)inSophie Schaffer(Chief Operating Officer)inCharlie Walch(Chief Financial Officer)in
Co-investorsHalogen Ventures Management Company LlcInnovation DepotTechstarsThird DerivativeInvested Development
Accipiter Biosciences uses computational protein design to develop de novo, single-agent protein therapies that engage multiple cell-surface receptors at once, functioning as agonists.
AI & Machine LearningBiotechDeep TechSeattle, US
Matthew Bick(Executive Officer, Director, Promoter)inJavier Castellanos(Executive Officer, Director, Promoter)inHector De Jesus Rincon Arano(Executive Officer, Promoter)Heather Redman(Director)Randall Schatzman(Director)William Canestaro(Executive Officer)in
Co-investorsFlying Fish VenturesArgonautic VenturesColumbus Venture PartnersPack VenturesWRF Capital
Acerta provides an industrial AI analytics platform for discrete manufacturers to identify and resolve production defects early, reducing scrap, rework, and downtime.
Advanced ManufacturingAI & Machine LearningEnergyEnterprise SoftwareKitchener, CA
Greta Cutulenco(Founder)in
Co-investorsBDC Fund Investments (Fund-of-Funds)BDC Industrial Innovation Venture FundBDC Thrive Venture Fund for WomenBDC Venture CapitalGarage CapitalL-SPARK+7 more
Acorai develops a non-invasive, handheld heart monitor that estimates cardiac and pulmonary pressures (including PCWP and RAP) and hemodynamic congestion trends to help clinicians manage and personalize heart failure therapy.
AI & Machine LearningDigital HealthMedical Devices
Co-investorsCapital Q® Ventures Inc.CARMA FUNDMeridian Health VenturesSupermarket
Toronto-based Ada Support builds enterprise AI customer service agents that automate resolution across chat, email, voice and messaging.
David Hariri(Founder)inMike Murchison(Founder)in
Co-investors515 VenturesAccelBessemer Venture PartnersDMZDMZ VenturesFirstMark Capital+10 more
Adaviv offers an AI-based "Lean Cultivation Agent" that helps farms track crop health, team productivity, and work quality through mobile apps, computer vision, and WhatsApp/SMS-based insights.
AgTechAI & Machine LearningRoboticsSaaS
Ian Seiferling(Co-founder & CEO)inMoe Vazifeh(Co-founder)Julian(COO)
Co-investorsDelta Emerald VenturesEmerging VenturesMilemark Capital PartnersNew Stack VenturesREMUS CapitalAiSprouts VC
Adept Materials develops advanced materials for building envelopes that improve energy efficiency, durability, and moisture management without sacrificing comfort.
Advanced ManufacturingCleantechConstruction TechDeep TechNew MaterialsSomerville, US
Derek Stein, Ph.D.(Founder & CEO)Derek Stein(Founder / Inventor)
BoardMiguel Galvez(Director)Daniel Cromie(Director)
Co-investorsAnorak VenturesBantam GroupSlater Technology FundThird Derivative
Adeptmind builds generative AI tools for retailers, offering AI-powered merchandising, product discovery, personalization, and marketing/ROAS optimization for e-commerce and omnichannel shopping.
AI & Machine LearningE-commerceRetail Tech
Jing He(Founder)inG Wu(Founder)in
Co-investorsDMZInnospark Venturesnoa
AG Data Center builds modular, containerized edge data center infrastructure for deploying AI compute directly at remote sites such as hospitals, universities, utilities, and government facilities.
AI & Machine LearningCleantechClimate TechCloud ComputingData & InfrastructureIoTBeaverton, US
Buchanan Eugene Robert(Executive Officer)
Co-investorsTechstars
Aegiq develops networked photonic quantum systems, including a quantum computer and photon sources, intended for practical large-scale deployment.
Deep TechHardwareQuantum ComputingSemiconductorsUK, GB
Scott Dufferwiel(Founder)inMaksym Sich(Founder)
Co-investorsDeepbridge CapitalGIMIC Ventures
Affable BPM offers an AI-powered compliance platform for healthcare organizations, combining UniComply for monitoring regulations, policies, contracts, and audits with AffableFLOW for no-code workflow automation and an AI-driven compliance training LMS.
AI & Machine LearningHealthtechSaaS
Co-investorsSybilla Masters
Agnostiq (now part of DataRobot) provides an agent workforce platform for building, operating, and governing enterprise AI agents, including tools like Covalent for orchestrating compute to deploy agents across edge, cloud, or on-prem environments.
AI & Machine LearningCloud ComputingEnterprise Software
Co-investorsDifferential VenturesGreen Egg VenturesScout VenturesScout VenturesBoost VCTensility Venture Partners
ai-coustics provides an audio reliability layer with speech technology such as Voice Focus, which removes background noise and other voices to improve transcription accuracy and keep voice agents responsive in noisy environments.
AI & Machine LearningDeep TechDeveloper ToolsSan Francisco, US
Arne Corvin Jaedicke(Executive Officer, Director, Promoter)Fabian Helmut Seipel(Co-founder & CEO)Corvin Jaedicke(Founder)inFabian Seipel(Founder)
BoardBORIS GOLDEN(Director)inSitar Teli(Director)in
Co-investorsInovia CapitalAcurio VenturesConnect VenturesConnect VenturesPartech VenturesFOV Ventures
Avalo uses machine learning to accelerate crop breeding, developing improved plant varieties such as fast-maturing broccoli, adaptive sugarcane, heat-resilient tomatoes, and low-input cotton.
AgTechAI & Machine LearningBiotechClimate TechDurham, US
Mariano Alvarez(Founder)inBrendan Collins(Founder)
BoardLaurie Menoud(Director)in
Co-investorsAt One VenturesBetter Ventures Central LlcBlue Bear Capital PartnersGermin8 VenturesGiant Ventures Global LlpGreycroft+1 more
AiDEN provides an automotive software platform that runs natively on vehicle infotainment screens, using real-time vehicle data to deliver contextual services, automate workflows, and unify fragmented in-car experiences.
AI & Machine LearningMobility & TransportationSaaS
Co-investorsBand of AngelsBlu Venture InvestorsRSCM
Aitiologic is a molecular diagnostics and precision medicine company that uses AI-powered bioinformatics to translate disease biology into clinical insight.
AI & Machine LearningBiotechDigital HealthMedical DevicesVienna, AT
Andreas Posch(Founder)inRebecca Ertl(Chief Medical Officer)in
Co-investorsPUSH Ventures
Alan provides health insurance, provident insurance (prévoyance) and prevention services for self-employed individuals, companies of all sizes, retirees, and public-sector workers, combining coverage with a digital app for reimbursements, telehealth consultations (Clinique Alan), and wellness features.
Digital HealthHealthtechHR TechInsurTechParis, FR
Charles Gorintin(Founder)inJean-Charles Samuelian-Werve(Founder)inJean-Charles Samuelian(Founder)
Co-investorsAgoranovCoatue ManagementIndex VenturesKima VenturesOriginsPartech Ventures+13 more
Premier marketplace connecting companies with top sales and business development talent in the United States.
Co-investorsCardinia VenturesStartX
ALAViDA Substance Use is a digital care program for substance use, offering 24/7 access via any device to a specialized care team and clinically-validated activities.
Digital HealthMental HealthWellness & Fitness
Co-investorsPallasite VenturesNimbus Synergies Inc.
Albus Health develops clinically validated monitoring technology that tracks respiratory metrics, heart rate, and cough frequency to support clinical studies.
BiotechDigital HealthHealthtechMedical Devices
Prof Maarten De Vos(Head of R&D)
Co-investorsMeridian Health VenturesParkwalk AdvisorsUCeed Funds
Alexi builds private cloud AI infrastructure for law firms, enabling intelligent systems that connect knowledge, workflows, and data while maintaining client control and security.
AI & Machine LearningEnterprise SoftwareLegalTechToronto, CA
Mark Doble(CEO at Alexi)in
Co-investorsBeresford VenturesDraper AssociatesDrive CapitalFf Venture CapitalForefront VentureTechstars+1 more
Allium manufactures stainless-clad rebar that meets the AASHTO M 329M standard, offered in a full size range (#3–#18) and ASTM A615 and A706 specifications.
Advanced ManufacturingCleantechConstruction TechNew MaterialsPeabody, US
Steven Jepeal(Cofounder)inSam McAlpine(Founder)in
Co-investorsAera VCAlumni VenturesBay Bridge Ventures ClimateCastor VenturesPropeller VC
AlphaOne Robotics develops robotic systems for warehouse and logistics automation, specifically designed to automate truck unloading and palletizing operations.
AI & Machine LearningLogistics & Supply ChainRobotics
Tim Criswell(Founder)inMatt Middleton(Founder)Alex Criswell(Founder)inSamarth Rajan(Founder)in
AQT develops quantum computers and quantum algorithms to solve complex problems across industries including aerospace, chemistry, materials science, and finance.
Cloud ComputingDeep TechHardwareQuantum ComputingInnsbruck, AT
Thomas Monz(Co-Founder & CEO)inRainer BlattPeter Zoller
Develops alternative textile materials to replace polyester and reduce the fashion industry's plastic consumption and carbon emissions.
Advanced ManufacturingBiotechCircular EconomyClimate TechNew MaterialsToronto, CA
Myra Arshad(Founder)inAvneet Ghotra(Founder)in
Co-investorsAmplify CapitalBeresford VenturesCollaborative FundGarage CapitalIT-Farm CorporationMaiora Rebel Ventures+5 more
Altay Therapeutics develops small molecule inhibitors targeting transcription factors to treat serious diseases including facioscapulohumeral muscular dystrophy and cancer.
BiotechDigital HealthHealthtechMedical DevicesSan Francisco, US
Ali Ozes(Founder)inOsman Ozes(Founder)inJAMES BREITMEYER(Executive Officer, Director)ERIC BJERKHOLT(Director)MIKE GREY(Director)ESTER SKLARSKY(Director)
Co-investorsJude GomilaTachyon VenturesY CombinatorFshd Global Research Foundation
Altiroenergy develops clean energy solutions, though the specific products or services are not detailed on the about page.
CleantechClimate TechEnergy
Samson Bowen-Bronet(Chief Executive Officer)Martin Aralov(Chief Technology Officer)Nic Pinkerton(Chief Operating Officer)
BoardProf. Jeff Bergthorson(Chief Scientific Advisor)
Co-investorsBoxOne VenturesHAXSOSVUCeed FundsUCeed
Altis Labs provides a web-based platform that applies AI models to medical imaging data to generate reproducible predictions and quantifications for clinical trials.
AI & Machine LearningBiotechDigital HealthHealthtechMedical DevicesToronto, CA
Felix Baldauf-Lenschen(Founder & CEO)inJohn(CTO)
Co-investorsDebiopharm Innovation FundFusionOrbiMedBenchstrength Partners
Altrove uses machine learning and AI combined with crystal simulation, high-throughput lab experimentation, and materials characterization to discover, synthesize, and scale novel materials as substitutes for vulnerable existing materials.
Advanced ManufacturingAI & Machine LearningDeep TechEnterprise SoftwareNew MaterialsParis, FR
Thibaud Martin(Founder)inJoonatan Laulainen(Founder)in
Co-investorsContrarian VenturesEmblemEntrepreneur FirstAlvenBpifranceFJ Labs
AlumaPower develops firm, dispatchable power technology aimed at addressing shortfalls in reliable 24/7 electricity for demand from AI data centers, re-industrialization, and electrification.
CleantechClimate TechEnergyHardwareSarnia, CA
Geoffrey Richard Steven Godwin(Director)Rob Alexander(Co-Founder & CEO)inHenk VandenEnde(Co-Founder & EVP, Business Development)inGeoff Sheerin(Inventor, Co-Founder & CTO)Richard Godwin(Co-Founder & Board Member)inPaul Simpson(Co-Founder & Board Member)in
Co-investorsBDC Fund Investments (Fund-of-Funds)BDC Venture CapitalE8 AngelsStarbridge Venture Capital LlcBioindustrial Innovation Canada
Ammobia develops a novel ammonia production process that operates at low pressure and low temperature, achieving record-setting conversion rates.
Advanced ManufacturingCleantechEnergySan Francisco, US
Karen Baert(Co-founder & CEO)inTristan Gilbert(Co-founder & CTO)in
Co-investorsChevron Technology VenturesShell VenturesAIR CapitalAlumni VenturesCastor VenturesCollaborative Fund+7 more
Amphitrite uses satellite data and artificial intelligence to provide ocean intelligence and forecasting services for maritime operators.
AI & Machine LearningClimate TechData & Infrastructure
Alexandre Stegner(CEO)inEvangelos Moschos(CTO)in
New York City, US
Jason Cohen(Executive Officer, Director, Promoter)Lewis Cohen(Director)Karl Gemperli(Director)in
BoardNaoki Kamimaeda(Director)
Co-investorsBetter Food VenturesGlobal BrainSony Ventures CorporationTechstarsBits x BitesHyperplane Venture Capital+1 more
Ananya Health develops a portable, battery-powered cryoablation platform for treating pre-cancerous cervical lesions at the point of care in any clinic setting.
FemTechHardwareHealthtechMedical DevicesSan Francisco, US
Anu Parvatiyar(Cofounder & CEO)inWei-Hsiang Chang(Director)Allen Chang(CTO)Julie Yip(Cofounder & Lead Engineer)
Co-investorsDream Variation VenturesY CombinatorAgrolimen VenturesEHA Impact VenturesHarvard Management CompanyVenture Investment Associates+1 more
Angel City Bio is a physician-scientist founded pharmaceutical company developing bile-acid-based treatments for gastrointestinal diseases, with programs targeting indications such as GLP-1-associated gallbladder disease and Crohn's disease.
BiotechDigital Health
Anomaly Games is a studio that builds viral games and consumer apps for emerging platforms, using an in-house infrastructure stack and AI across design, content generation, and live operations.
AI & Machine LearningConsumerCrypto & Web3GamingNorth York
Long Do(Executive Officer, Director)
Co-investorsDecasonicTriptyq Capital
Antora manufactures thermal battery systems for long-duration energy storage, serving manufacturers and data centers seeking to tap into low-cost renewable power.
CleantechClimate TechEnergyEnterprise SoftwareFintechHardwareImpact & Social GoodNew MaterialsSunnyvale, US
Andrew Ponec(Founder)inDavid Bierman(Founder)inJustin Briggs(Founder)inDavid Bierman, Ph.D.(Chief Commercial Officer, co-founder)Justin Briggs, Ph.D.(Chief Operating Officer, co-founder)Alfred Johnson(CEO & Co-Founder)
Co-investorsAndreessen HorowitzBlackRockTemasekBreakthrough Energy VenturesCongruent VenturesDeepwater Asset Management+24 more
AOA Dx develops a blood-based liquid biopsy platform using mass spectrometry and machine learning to detect ovarian cancer at early stages through tumor-associated biomarkers in serum.
AI & Machine LearningBiotechDigital HealthHealthtechMedical DevicesDenver, US
Oriana Papin-Zoghbi(Founder)inAlex Fisher(COO)inAnna Jeter(Founder)inOriana Zoghbi-Harb(Executive Officer, Director)Abigail Mcelhinny(Executive Officer)inRob Mayers(Recruiter)
Co-investorsAlleyCorpGood Growth CapitalJoyance PartnersY CombinatorAstiaAurum Venture Partners+38 more
Aperture Bio develops technologies to translate human tumor biology in order to reduce risk in preclinical drug development.
AI & Machine LearningBiotechHealthtechAllston, US
Laura Kelley(Executive Officer, Director)Hannah Peterson(Executive Officer, Director)
Co-investorsGurtin VenturesTechstars
Applikate Technologies is a hardware and software company that has built an automated histology platform with integrated digital imaging, which stains and images whole tissue samples without physical slicing to produce histopathology data in hours.
HardwareHealthtechMedical DevicesWashington, US
Richard Torres(Co-founder)inMichael Levene(Co-founder)inDavid Hint(Director)
Co-investorsBalderton Capital
Aqua-Cell develops batteries for energy storage used to defer costly electricity substation upgrades, enable peak-load-shifting for factories and industrial facilities, and provide renewable self-sufficiency for microgrids and remote communities.
CleantechClimate TechEnergyHardwareKitchener, CA
Keith Cleland(Co-founder and CEO)inEllsworth Bell(Co-founder and CTO)in
Co-investorsStartup TNTWaterloo Accelerator Centre
Aquaai builds bio-inspired, fishlike underwater vehicles equipped with cameras and plug-and-play sensors to collect subsurface water data, offered on a Fish-as-a-Service model.
Climate TechDeep TechRobotics
LianeSimeon P.(Founder)in
Co-investorsAd Astra VenturesBackstage Capital
Aquacycl provides onsite industrial wastewater treatment using its patented technology to treat high-strength wastewater without dilution, offering energy-neutral operation, lower greenhouse gas emissions, and water reuse.
Circular EconomyCleantechClimate TechImpact & Social GoodEscondido, US
Orianna Bretschger(Executive Officer, Director)inMichael Jones(Director)Anil Jha(Director)
Co-investorsAd Astra VenturesKeshif VenturesNext Wave Impact8090 Industries
Aquarry develops technology solutions focused on mine closure and remediation.
CleantechClimate TechImpact & Social GoodNew Materials
Kate Murphy, PhD(Founder)in
Co-investorsAvilaCollaborative FundDeep Science VenturesEvergreen Climate Innovations
Arda engineers plastic-free materials from spent grain sourced from brewers and distillers, using protein hierarchies and nontoxic chemistry.
Advanced ManufacturingBiotechCircular EconomyNew MaterialsLondon, GB
Brett Cotten(CEO)inEdward TJ Mitchell(CTO)in
Co-investorsEntrepreneur FirstGreen Angel VenturesOyster Bay Venture CapitalPlug and Play VenturesSatganaSerpentine Ventures+2 more
Areto Labs offers a responsible AI platform that combines human judgment with AI to detect and filter harmful online content such as hate speech and technology-facilitated gender-based violence, helping global brands and public figures build safer digital communities.
AI & Machine LearningCybersecuritySaaS
Lana(Co-founder)Kasey(Co-founder)Jacqueline Comer(Co-founder)in
Co-investorsEdmonton UnlimitedScaleGood Fund LP (powered by TELUS)Startup TNTThe 51 VenturesUCeed FundsUCeed+1 more
Argospace provides launch and transportation services for spacecraft and satellites beyond low Earth orbit (LEO), including cislunar and interplanetary missions.
Deep TechHardwareSpace TechEl Segundo, US
Ryan Carlisle(Founder)inKirby Carlisle(Founder)inRobert Carlisle(Founder)in
Co-investorsAIR CapitalCrosslink CapitalEarthrise VenturesGaingelsHelios CapitalMana Ventures+4 more
Ariel Precision Medicine offers an AI-driven platform that integrates genomic and clinical data (including EHR/EMR records, lab results, and scientific literature) to produce peer-reviewed, evidence-based reports.
AI & Machine LearningBiotechDigital HealthPittsburgh, US
Jessica Gibson(Executive Officer, Director)inDavid Whitcomb(Director)inJohn Moore(Executive Officer)
BoardStephan Dietrich(Director)inMary Del Brady(Executive Officer, Director)David Smith(Director)
Co-investorsString VenturesThe Robotics HubLead Edge CapitalRobotics Hub
ARIX combines robotics and data analytics to inspect and manage critical industrial assets.
AI & Machine LearningDeep TechEnergyIoTRoboticsJackson, US
Dianna Liu(President and CEO)in
Co-investorsAlleyCorpContour Venture PartnersDorm RoomEnergy Transition VenturesGaingelsInnovation Catalyst+6 more
Arkangel connects medical science and artificial intelligence to help healthcare teams make faster clinical decisions and reduce documentation errors.
AI & Machine LearningDigital HealthEnterprise SoftwareHealthtech
Co-investorsBroom Ventures468 Capital
Armilla AI is a managing general agent offering liability coverage, performance warranties, and risk assessments for AI systems.
AI & Machine LearningData & InfrastructureEnterprise SoftwareFintechInsurTechToronto, CA
Dan Adamson(Founder)inKarthik Ramakrishnan(Founder)inBaiju Hasmukhrai Devani(Executive Officer, Director)Baiju Devani(Founder)Rahm Hafiz
BoardRaif Barbaros(Director)in
Co-investorsBeresford VenturesBetaworksDifferential VenturesMistral Venture PartnersMS&AD VenturesRebel Fund+8 more
Arolytics appears to work on emissions detection and monitoring, with a focus case study on methane emissions at oil and gas facilities.
AI & Machine LearningClimate TechEnergySaaS
Co-investorsAccelerate FundBDC Sustainability Venture FundStartup TNTBDC Capital CorporationMetiquity VenturesYaletown Partners
Arrowsmith Genetics is a preclinical-stage drug discovery company developing therapeutics from genetic research conducted at UBC and BC Cancer.
BiotechDeep TechVancouver, CA
Phil HieterPeter Stirling(Founder)inNigel O'Neil(Founder)in
Co-investorsInnovation UBC
Arylla produces invisible ink tags using nanotechnology that can be applied to fashion products and read via smartphone to enable authentication, traceability, and personalized customer experiences.
Advanced ManufacturingDirect to ConsumerIoTNew MaterialsRoboticsKitchener, CA
Perry Everett(Business Development)inBenjamin Rasera(Founder)inGraham Thomas(Founder)in
Co-investorsY CombinatorVTF CapitalAgrolimen VenturesOriza HoldingsU-Start
AgTechIthaca, US
Frank Schroeder(Director)Jay Farmer(Executive Officer, Director)in
BoardAlex Bondar(Director)inKyle Welborn(Director)in
Co-investorsAcre Venture PartnersPonderosa VenturesCultivation Capital
Ashored develops fixed-gear fishing technology aimed at reducing marine animal entanglements caused by traditional buoy-and-rope trap systems.
Climate TechHardwareImpact & Social Good
Co-investorsInnovative Solutions Canada
Aspero Medical develops the Pillar balloon overtube solution with micro-textured design to improve control and anchoring during balloon endoscopy for small bowel diagnosis and treatment.
Deep TechHealthtechMedical DevicesBoulder, US
Mark Rentschler(Co-Founder, CEO)inSteven Edmundowicz, MD(Co-Founder, Chief Medical Officer)
BoardMike Freeman(Director)in
Co-investorsInnosphere VenturesRockies Venture Club
Asteroid Mining Corporation is an applied sciences firm focused on asteroid mining operations.
Deep TechSpace Tech
Asynchronics develops NeXosim, a simulation framework for space systems that enables high-fidelity modeling and validation of spacecraft and satellite hardware.
Deep TechDeveloper ToolsSpace Tech
Adam Chikha(Co-Founder & CEO)in
Co-investorsHeartfelt CapitalHEC Paris IncubatorSunfish PartnersSunfish Partners
Atlas Metrics provides an AI-powered platform that combines non-financial data from multiple sources to help financial institutions manage ESG, climate, and financial risks while automating regulatory reporting and compliance.
AI & Machine LearningClimate TechDeveloper ToolsFintechLondon, GB
Robert Stojnic(CEO)inRoss Taylor(CTO)inWladimir Nikoluk(Founder)in
Co-investorsb2ventureBerliner Volksbank VenturesCherry VenturesEntrepreneur FirstKickstart InnovationRedstone+7 more
Atmose builds instruments to measure and condition ultrafine aerosol particles in a range of field locations, addressing gaps in conventional air-quality measurement systems.
CleantechClimate TechHardwareEdmonton, CA
Tyler Johnson(Founder)in
Co-investorsInnovative Solutions Canada
Atomwise uses artificial intelligence and machine learning to discover novel small-molecule drugs, with a current focus on developing treatments for immune and inflammatory diseases.
AI & Machine LearningBiotechDeep TechSan Francisco, US
Izhar Wallach(Founder)inAbraham Heifets(Founder)inYan Zhao(Executive Officer)inStephen Worland(Executive Officer, Director)
BoardRobert Mittendorff(Director)inAdam Seabrook(Director)in
Co-investorsAurum Venture PartnersB Capital GroupCerity Partners VenturesDraper AssociatesMission and MarketThreshold Ventures+7 more
Audette provides a platform for asset and portfolio managers to identify and prioritize building retrofit investments, using data analysis to uncover high-return opportunities that improve net operating income and reduce emissions.
PropTechSaaS
Co-investorsBuoyant Ventures Management, LlcEnergy Impact PartnersForesight CanadaGaingelsModerne VenturesPanache Ventures+3 more
Audio Design Desk is a macOS application for sound design and music creation, offering AI-powered search across a library of 70,000+ royalty-free sound effects, loops, and music cues to build audio layers for video.
AI & Machine LearningCreator EconomyMedia & Entertainment
Co-investorsBeresford Ventures
Aufero Medical develops TruContact, an add-on accessory device that provides on-demand catheter stability during atrial fibrillation ablation procedures.
HardwareHealthtechMedical Devices
Daniel Gelman(Founder & CEO)Maria Drangova(Founder)Allan Skanes(Founder)
HealthtechNashville, US
STEPHEN KALINSKY(Executive Officer, Director)Jared Meyers(Executive Officer, Director)inStephen Kalinksky(Executive Officer)
Aurora Hydrogen develops microwave-driven methane pyrolysis technology to produce low-cost clean hydrogen without CO₂ emissions.
CleantechClimate TechDeep TechEnergyNew MaterialsEdmonton, CA
Co-investorsEnergy Innovation CapitalThird DerivativeChevron Technology VenturesShell Ventures
Autozen operates an online platform for selling used cars, connecting individual car sellers with buyers.
ConsumerMarketplacesMobility & Transportation
Sean Mactavish(CEO)in
Co-investorsVanedge CapitalVanedge Capital Limited Partnership
AuX Labs uses precision fermentation to produce recombinant milk proteins, starting with casein, that replicate the functional performance of dairy without animals.
BiotechClimate TechFoodTech
Ted Jin(Founder)
Co-investorsAlwyn CapitalBluestein VenturesCongruent VenturesNàdarra VenturesNatural Products CanadaNYA Ventures+2 more
Aview provides multimedia translation and dubbing services to help content creators and entertainers expand their audience internationally across social media platforms.
AI & Machine LearningCreator EconomyMarketing TechMedia & EntertainmentAncaster, CA
Co-investorsBoxOne VenturesTechstars
Co-investorsParticleTera Ventures
Avro Life Sciences develops platform technology for novel drug delivery through passive transdermal administration.
BiotechHealthtechMedical DevicesWaterloo, CA
Shak Lakhani(Founder)inKeean Sarani(Founder)in
Co-investorsEmbark VenturesFifty YearsGarage CapitalHeuristic Capital PartnersJude GomilaUpHonest Capital+10 more
Awake Labs provides a digital platform combining smartwatch, mobile, and web dashboard technologies to measure stress in real-time for adults with intellectual or developmental disabilities.
AI & Machine LearningDigital HealthHealthtechIoTMental HealthWellness & FitnessToronto, CA
Co-investorsTechstars
Axiom Therapeutics runs a drug discovery platform for covalent inhibitors, applying machine learning to speed up physics-based simulations.
BiotechLondon, GB
Ryan Geiser(CEO)inChris Haggard(CTO)inSofia Dahoune(Director)Ryan Geiser, PhD(Founder)in
Co-investorsEntrepreneur FirstGaingelsLunar VenturesPlug and Play VenturesSamos InvestmentsTranspose Platform Management+2 more
Axoft is developing soft, tissue-mimicking neural implants and supporting bidirectional electronics that record and stimulate brain activity through a minimally-invasive burr-hole procedure.
AI & Machine LearningDeep TechMedical DevicesCambridge, US
Paul Le Floch(Executive Officer, Director)inTianyang Ye(Director)inRachel Sha(Director)in
BoardChia An Lee(Director)Benjamin Pless(Director)
Co-investorsAlumni VenturesAmino CapitalArcherman CapitalBlindspot Ventures Management CoCastor VenturesSafar Partners+4 more
Axonis Therapeutics is a biotechnology company developing small-molecule medicines that target KCC2, a mediator of inhibition in the brain, to treat neurological disorders such as epilepsy and pain.
BiotechDeep TechBoston, US
Shane V. Hegarty(Chief Scientific Officer & Co-Founder)inJoanna Stanicka(Chief Executive Officer, President & Co-Founder)inJeff Imbaro(Chief Operating Officer)inTiasha Shafiq(Chief of Staff)in
BoardCorey . Goodman(Director)inJonathan Leff(Director)in
Co-investorsSofinnova VenturesvenBio PartnersMRL Ventures FundCivilization Ventures Management, LlcHatteras Venture PartnersIaso Ventures+8 more
Félix Bélisle Dockrill(Founder)in
Co-investorsBastien Family OfficeBDC Industrial Innovation Venture FundEcofuel FundFront Row Ventures
Ayrton Energy develops a hydrogen storage and transport solution based on a proprietary liquid organic hydrogen carrier (LOHC) and electrochemistry, storing hydrogen as a liquid at ambient conditions so it can be moved using existing fuel infrastructure.
CleantechClimate TechEnergyCalgary, CA
Co-investorsBDC Climate Tech Fund IIClean Energy VenturesForesight CanadaMaRSMaRS Investment Accelerator Fund (IAF)SOSV+6 more
Bairitone develops a wearable patch-based system that maps airway vibrations to detect sleep apnea obstruction causes without MRI, X-ray, or ultrasound.
Digital HealthHealthtechMedical DevicesHouston, US
Onur Kilic(Executive Officer, Director)inMeagan Pitcher(Executive Officer, Director)Brittain Cross(Executive Officer, Director)
Co-investorsGolden SeedsSouth Loop VenturesSupermoon Capital
BANIQL uses an atmospheric-pressure leaching process to convert nickel ore into battery-grade mixed hydroxide precipitate (MHP), with nickel sulfate and nickel metal in development, avoiding HPAL autoclaves and using far less energy.
CleantechClimate TechDeep TechNew Materials
Eric Januar(Founder)inSeungwan KiminWilly Halim(Founder)inAristotle V.(Founder)in
Co-investors500 GlobalBEENEXTGenesia VenturesA2D VenturesThird Derivative
BarrelWise makes the FS1, a device that lets cellar workers measure free SO₂ directly at wine barrels with results uploaded to a cloud database for winemakers and lab teams to analyze.
AgTechHardwareIoT
Co-investorsEmmertechAg Capital CanadaConexus Venture Capital
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
1000 Kelvin16-Bit20/20 OptimEyes Technologies Health3852.AI company401 Labs5 Prime Sciences8Xlabs9BioA&K Robotics Artificial IntelligenceA4IAbout:EnergyAboutenergyAbsco Therapeutics (AbscoTx) CancerAccéder Supply ChainAccsys DiagnosticsAccurolabAcs Automated Cleaning Services IncAcumino, Inc. ManufacturingAdam AerospaceAdaptive FinanceAdaptive InsuranceAdaptive PulseAdaptronicsAddGraft TechnologiesAddyAdhashAdolusAdvaiAdvanced Intelligent SystemsAeroflux Braking SystemsAgate SensorsAgenttAggregate IntellectAgritrackAi Health HighwayAi SpacefactoryAI VALI IncAi4Eyes Medical TechnologiesAibaAifred HealthAikoAires Technology IncAiroAisimpro IncAispannerAixeloAlchemity, LLC ClimateAlgae-C OceansAlgocianAlgorithm GAll Day TaAll SkinAllotheraAlpha CognitionAlphaguardAlpharailAltevaAltoAltQ.ai Artificial IntelligenceAlunaAmplifiedSpace SpaceAnnapurna SuiteAnsurAperture SpaceAqariosAqua Battery companyAquark TechnologiesAquilaArblingArca DynamicsArcascopeArch AI companyArctic Space TechnologiesArctorisArcturusArda companyarf Financial companyArfront Technologies IncArkion PrimeArma BiosciencesArmada Technologies LtdArtiste-qb NetAruna Revolution Health IncAsclepios TechAstroteq.ai SpaceAtdepth MrvAtheraxonAtlantiq AiAtomicAtomos Nuclear and Space CorporationAtorvia Health TechnologiesAudible RealityAudyse companyAugment BiologicsAugmentalAutomatAutomation IntelligenceAutonomous Vehicle Organization companyAuxiliumAvaylAvolAwe Technologies LlcAWL-Electricity Supply ChainAxcell LabsAxem NeurotechnologyAXIAS AIAxtion Independence Mobility companyAYE3D companyAyrflo Innovation Labs IncBauxite Technologies
Browse all 446 investments with full details →
▶246 more tracked companies
BeagleBeam Medical IncBeatdappBeaver HealthBeitBelive.ai CommerceBenchmark Space SystemsBenchsciBereda Training IncBetter DairyBiconomyBidaliBIG BLUE TECHNOLOGIES INC.Big CouchBigthinxBinta Financial Inc.Bio Mimir companyBiocurieBiofect InnovationsBioform SolutionsBiohuntress TherapeuticsBioHybrid Solutions LLCBiointelligenceBioMBiome RenewablesBiomotumBionicaBiosenseBiotech Squarebiotx.ai HealthBiowegBioXplorBirch BiosciencesBirdseyeview TechnologiesBittensorBlablaBlassaBlaze Energy Technologies CorporationBlockalyticsBlockscopeBlockseatBlokBloomBloomscoBlossom Microbial Technologies companyBlue CubedBlue JBlue Lion LabsBlue Mesa HealthBlue Ocean GearBlue Planet EcosystemsBlueberry PrimeBluefield Technologies IncBluefinsBluegrid By RimotBluenodeBlueQubitBluesonde Technologies IncBlumindBoonBorealis WindBoston QuantumBotlhale AiBotmindsBotpressBoxcatBrain Spec companyBrainFxBrayfoil TechnologiesBreathe Battery TechnologiesBreathesuiteBreeze TrafficBreeziBrenus PharmaBridge GenomicsBridge7BridgitBrightspaceBrilliant Matters Organic ElectronicsBrimstoneBrink BionicsBrisk SynergiesBriziBroadsight Technology Corp.Brown FoodsBubo.ai CommerceBugseqBuild BeyondBuskr MediaBx Smart LabsByosByteratC12 Quantum ElectronicsCadence Final Document ServicesCALMWAVECalogy SolutionsCalumixCAMBRIAN WORKS, INC.Canadian Strategic Missions CorporationCanurta TherapeuticsCanvassCapacitech EnergyCapIntelCaplyzerCapsigenCaptain T Cell GmbHCaptivate TechnologyCapturaCapture Smart MetersCapwellCarboMatCarbon BlockCarbon CellCarbon FarmCarbon UpcyclingCarbonlumeCarbonovaCarbonquestCardiaxis Medical IncCare WeatherCareteamCaristo DiagnosticsCascade AiCase45CaseCTRLCashewCatena BiosciencesCauraCDLCelerity Craft Inc.Cell BauhausCell Chorus companyCellbricksCellensCellFECellgro TechnologiesCense AgCentinelCerebriCerecura Nanotherapeutics Inc.Ceres SolutionsCetos WaterChargeLab +MoreChargespotCheckstepChemFinityChild Health ImprintsChinova BioworksChisel Artificial IntelligenceChroma TechnologiesChrysalabsCibotica IncCielaraCime TherapeuticsCipher Skin, Inc.Circadian Positioning Systems, Inc.Circe IndustriesCircuit Mind LimitedCisLunar IndustriesCitizen HexClanzClarityClean O2Cleancard companyClear Cost Agtech IncClear CurrentClee MedicalClimatexCliniaClirCloreCloverleaf BioCo ReactiveCo2BrewCoalesce.ai Artificial IntelligenceCoastal Genomics IncCobionixCogitatCogniFrame Inc.Cognitive Network SolutionsCognitive SpaceCognivive, Inc.CogramCogwear LlcCohesicCohesysCoLabColoursmith PrimeCompass LabsCompatioCompression.ai PrimeConcarloConcha LabsConcordConnect EarthConnekticaConry TechContinuum IndustriesContxtfulConvergence Medical SciencesCooper Pet CareCopoly.ai Biomedical EngineeringcopperstoneCordance MedicalCorolCulturePulseDalhousie University Faculty of ManagementDeep GenomicsDiffraqtionEavorENDEAVOR COMPOSITES, INC.EsmtFireSwarmHecIcarus Robotics CorporationIntellaIS-WirelessKA ImagingLodge SystemsMETHYS DXMetropolitan TechnologiesMonavaNeurobusNorthNorth Vector DynamicsNorthern Waves ABPCare+PHAIT, Inc.PolimiPropel Space Inc.QTASRoocaSeamoretechSerafin Labs, Inc.Sigen AIStratotegic Inc.TakeMe2SpaceTamuThistleTotexUc2CUnibocconiUtUwVellex ComputingVXB Aerospace
Exits · 3
1 IPOs · 2 acquisitions · showing 1ComcastNYSE: CCZ
Portfolio news
latest coverage across their companiesChrysalabs · simplify.jobs · Sep 5, 2026

Eavor · geothermalinsider.com · Aug 30, 2026

Antora Energy · finsmes.com · Jul 31, 2026
Alan · finsmes.com · Jun 29, 2026
Axoft · trysignalbase.com · Apr 30, 2026
Checkstep · trysignalbase.com · Apr 29, 2026
Frequently asked questions
- How many investments has Creative Destruction Lab (CDL) made?
- Creative Destruction Lab (CDL) has 446 tracked investments, 3 of which have exited, including 6 dated in the last 24 months.
- What stage does Creative Destruction Lab (CDL) invest at?
- Creative Destruction Lab (CDL) invests at the Pre-Seed, Seed stages.
- What is Creative Destruction Lab (CDL)'s typical check size?
- Creative Destruction Lab (CDL) typically writes checks of $50K – $250K.
- What sectors does Creative Destruction Lab (CDL) focus on?
- Creative Destruction Lab (CDL) focuses on Advanced Manufacturing, AgTech, AI & Machine Learning, Biotech, Cleantech, Climate Tech, Crypto & Web3, Deep Tech, Defense Tech, Digital Health, EdTech, Energy, Fintech, Healthtech, Logistics & Supply Chain, Mobility & Transportation, New Materials, Quantum Computing, Robotics, Sector Agnostic, Space Tech.
- Where is Creative Destruction Lab (CDL) located?
- Creative Destruction Lab (CDL) is headquartered in Toronto, CA.
- Does Creative Destruction Lab (CDL) lead rounds?
- Creative Destruction Lab (CDL) typically participates in rounds rather than leading them.
- Who does Creative Destruction Lab (CDL) co-invest with?
- Creative Destruction Lab (CDL) most often shares deals with Techstars, Y Combinator, Third Derivative, among 537 tracked co-investors.
Images
Co-investors · 20
True Ventures is an early-stage venture capital firm that has backed founders since 2005, partnering at the earliest moments of company building.
Balderton Capital is a European venture capital firm that backs technology startups.
Eclipse is a venture firm that backs entrepreneurs building companies in the physical and essential economy — industries tied to resilience, competitiveness, and security.
Spider Capital is an early-stage venture firm backing founders using applied AI to modernize complex enterprise industries, supported by experienced enterprise cloud operating executives.
Builders VC is a venture firm run by operators and investors that backs founders solving complex, mission-critical problems in industries dominated by legacy systems.
Sequoia Capital is a venture capital firm that partners with founders to build technology companies.
GV (Google Ventures) is a venture capital firm that has invested in AI and machine learning since its early days, backing more than 100 AI companies across infrastructure, life sciences, and applications.
Founder Collective is a seed and pre-seed stage venture capital firm that invests across sectors, describing itself as sector agnostic and anti-thematic.
Battery Ventures is a global investment firm that has backed more than 450 companies over its 40-year history, operating its investment staff as a single global unit.
Madrona Venture Group is a venture capital firm that backs founding teams at the seed, early, and acceleration stages, with a focus on Seattle, the Bay Area, and beyond.
Flybridge Capital Partners is an East Coast venture capital firm backing early-stage, AI-focused startups. Founded in 2002, it invests at the pre-seed and seed stages across AI applications, infrastructure, and related sectors.
IA Ventures is a venture capital firm that invests in early-stage software and frontier technology companies.
▶8 more co-investors
Costanoa VenturesZetta Venture PartnersWork-BenchMango CapitalPioneer Square LabsVisionaire VenturesMetamorphic VenturesOVO Fund
Firms observed investing alongside Creative Destruction Lab (CDL), from public investor directories. Shared companies are the overlap with Creative Destruction Lab (CDL)'s recorded portfolio.
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