Refactor Capital

Solugen develops a biomanufacturing platform using fermentation and bioprocessing technology to produce specialty chemicals at scale.

Advanced ManufacturingBiotechCleantechClimate TechHealthtechHouston, US

Sean Hunt(Founder/CTO)inGaurab Chakrabarti(Founder)in

BoardSeth Bannon(Director)in

Co-investorsFifty YearsFounders FundLowercarbon CapitalY CombinatorBaillie GiffordGIC+22 more

Santa Clara, US

Fred Turner(Executive Officer, Director)

Board seatZal Bilimoria· per SEC Form D · $7.5M raise · filed May 2018

64x develops infrastructure and manufacturing systems for next-generation medicines, focusing on genetic engineering, cell line development, and computational biology to enable scalability of advanced therapies.

AI & Machine LearningBiotechDeep TechHealthtechMedical DevicesSan Francisco, US

Lexi Rovner(Co-founder & CEO)in

Co-investorsFifty YearsFuture VenturesLifeforce CapitalRaptor GroupY Combinator

Able Health provides software for physician organizations to administer value-based care programs, including quality measure calculation and health plan coordination to reduce administrative overhead.

HealthtechSan Francisco, US

Rachel Katz(Founder/CEO)inSteve Daniels(Founder/President)in

Co-investorsLifeforce CapitalY Combinator

Adventris is a biotechnology company developing cancer immunotherapy treatments.

BiotechHealthtechBaltimore, US

Jen Herbach(Founder)inWilliam Collis(Founder)inMark Yarchoan(Founder)

Co-investorsY CombinatorIllumina Ventures

Aether develops additives that blend into engineering-grade nylons to enable faster, high-throughput fused filament (FFF/FDM) 3D printing while maintaining mechanical strength and dimensional accuracy.

Advanced ManufacturingAI & Machine LearningBiotechDeep TechHardwareNew Materials

Pavle Jeremic(Founder & CEO)Jay Zaveri(Co-Founder & President)

Co-investors4DX VenturesAbstract VenturesArtis VenturesBlue Bear VenturesBoxGroupCalm Ventures+7 more

AKASA provides generative AI solutions for healthcare revenue cycle management, helping health systems automate administrative workflows and reduce costs.

AI & Machine LearningEnterprise SoftwareHealthtech

Co-investorsAndreessen HorowitzCoatue ManagementFounders Circle CapitalBalaji SrinivasanPreface Ventures

Co-investorsBattery VenturesCross Creek Advisors

Astranis manufactures small, high-powered geosynchronous satellites equipped with advanced digital processing technology for global telecommunications and connectivity services.

Advanced ManufacturingDeep TechHardwareSpace TechSan Francisco, US

John Gedmark(Founder/CEO)inRyan McLinko(Founder/CTO)in

Co-investorsAndreessen HorowitzBlack FlagBoxGroupCantos VenturesCherubic VenturesCommonweal Ventures+37 more

A wearable device company developing brain-sensing technology using nanotechnology for consumer use.

Deep TechHardwareHealthtech

Co-investorsAccelCompoundVery Serious VenturesBlackRockLocalGlobeNorthzone+1 more

Avail is a modular blockchain infrastructure project building a data availability layer and unification stack for rollups.

Anurag Arjun(Founder)in

Co-investorsAmino CapitalCoatue ManagementJuniperoCyber CapitalFigmentFounders Fund+1 more

The company builds "Biological Adapters" that integrate living neurons with AI foundation models to improve performance and reduce training cost, and it operates an algorithm discovery platform based on principles from biological neural systems.

AI & Machine LearningBiotechDeep Tech

Co-investorsBanyan VenturesPrimary Venture PartnersWonder VenturesE1 Ventures

Berkeley Yeast develops engineered brewing yeast strains that provide consistent flavors, low diacetyl, and thiol-driven aromatics for craft breweries.

BiotechFoodTech

Co-investorsDYDX CapitalAnterra Capital

Betty Labs built Locker Room, a live audio app for sports fans, and was acquired by Spotify in March 2021.

Co-investorsScript Capital

BioRender is a software tool that enables scientists to create and share professional scientific illustrations and figures.

BiotechEdTechEnterprise SoftwareSaaSToronto, CA

Ryan Marien(Founder)inKatya Shteyn(Founder)inShiz Aoki(CEO and Co-founder)in

Co-investorsY CombinatorFifty YearsFundersClubStandard CapitalZeno Ventures

Los Angeles, US

Charles Mason(Executive Officer, Director)

Co-investorsPantera CapitalChapter One

Brelle develops a modular energy platform for high-performance machines, combining battery hardware, embedded AI-enabled software, and automated manufacturing.

Deep TechEnergyHardwareLos Alamitos, US

Martin Hermez(Founder)Nachiket V(Founder)

Co-investorsFirst Star Ventures

Causal Labs builds a Large Physics foundation Model to learn causality through physics and weather observations.

AI & Machine LearningDeep TechSan Francisco, US

Dar Mehta(Founder)Yue (Kelsie) Zhao(Founder)

Co-investorsKindred VenturesTranspose Platform Management

Checkerspot uses microalgae precision fermentation to produce specialized lipids and fats, including a bio-equivalent source of the sn-2 palmitate fat found in mother's milk, rare bioactive fatty acids, and tropical fat alternatives.

BiotechClimate TechFoodTechNew MaterialsAlameda, US

Scott Franklin(Executive Officer, Director)Charles Dimmler(Executive Officer, Director)John Krzywicki(CEO)Layla Ward(CFO)Casey Lippmeier(CTO)Leon Parker(SVP, Molecular Biology)

Co-investorsBaruch Future VenturesBreakout VenturesCavallo VenturesBuilders VCKdT Ventures

Clover Health is a health insurance provider offering low-cost plans with minimal premiums, copays, and prescription drug costs.

Digital HealthHealthtechInsurTechJersey City, US

Vivek Garipalli(Executive Officer, Director)Andrew ToyinKris Gale(Executive Officer, Director)

BoardNat Turner(Director)Mike Dixon(Director)Josh Kopelman(Director)in

Co-investorsFirst Round CapitalFloodgateGV (Google Ventures)Lifeforce CapitalToba CapitalSequoia Capital+1 more

Curative offers an employer-sponsored health insurance plan with $0 copays, $0 deductibles, and a single monthly premium, giving members access to a nationwide provider network, telehealth, and $0 preferred prescriptions.

Digital HealthHealthtechInsurTechAustin, US

Isaac Turner(Founder)inFrederick Edward Turner(Executive Officer, Director)Tami Denise Wilson-Ciranna(Chief Financial Officer)

Co-investorsDCVC (Data Collective)Jam FundUndeterred Capital

Enzyme develops a Quality Management System (QMS) software platform for life science companies including drug, biologic, device, and digital product manufacturers, designed to streamline regulatory workflows and generate FDA-ready documentation.

Enterprise SoftwareHealthtechMedical DevicesSaaSSan Francisco, US

Jared Seehafer(Founder/CEO)inJacob Graham(Founder/Vice President QA/RA)in

Co-investorsY CombinatorAg Startup Engine SeedSahsen Ventures

Epana Bio develops therapies for autoimmune diseases by leveraging genomics and AI to identify and target cellular origins of disease, with a focus on precision medicine for patient populations.

AI & Machine LearningBiotechDigital Health

Co-investorsBreakout LabsBreakout VenturesHAWKTAILHummingbird VenturesOMX VenturesKdT Ventures

Xometry provides an instant quoting and manufacturing platform that connects startups and enterprises with a global network of manufacturers to produce precision components from prototype through high-volume production.

Advanced ManufacturingB2B MarketplacesSaaS

Co-investorsAugust CapitalMaryland TEDCOTEDCO

Floodbase provides flood mapping technology and parametric flood insurance products that pay out based on the magnitude of flooding over a large area, enabling policies that settle within days of an event.

AI & Machine LearningClimate TechInsurTechBrooklyn, US

Bessie Schwarz(Executive Officer, Director, Promoter)Elizabeth Tellman(Executive Officer, Director, Promoter)

BoardMarty Schneider(Director)Sasha Brown(Director)John Loser(Director)in

Co-investorsBURNT ISLAND VENTURESEcosystem Integrity FundFloating PointGroundForce CapitalLOWERCARBONLowercarbon Capital+4 more

Fyto builds automated cropping systems that cultivate the aquatic plant lemna to recover farm nutrients and produce protein and starch, serving dairy and other farm operations.

AgTechClimate TechRobotics

Co-investorsCity LightBaukunstFirst Star Ventures

Gencove provides direct-to-consumer genetic sequencing and polygenic risk scoring for health insights.

BiotechDigital HealthHealthtechNew York, US

Tomaz Berisa(Executive Officer, Director)Joseph Pickrell(Executive Officer, Director)

BoardSara Eshelman(Director)in

Co-investorsBread And Butter Ventures, LlcSpero VenturesBalaji SrinivasanThird Kind Venture CapitalVersion One Ventures

General Galactic is a space infrastructure company focused on building orbital and extraterrestrial infrastructure, drawing inspiration from science fiction concepts like propellant generation for off-Earth settlement.

Deep TechHardwareLogistics & Supply ChainSpace TechEl Segundo, US

Halen Mattison(Cofounder)inLuke Neise(Cofounder)in

Co-investorsAntiHarpoon VenturesPathbreaker VenturesSeraphim SpaceUnruly Capital

Granza Bio develops immunotherapy treatments leveraging naturally-occurring attack particles that are released from cytotoxic immune cells to target diseases including cancers, autoimmunity, and infections.

BiotechDeep TechDigital HealthHealthtechSan Francisco, US

Prof. DustinAshwin Nandakumar(Founder)inAshwin Jainarayanan(Founder)inAshwin Menon Nandakumar(Founder)in

Co-investorsFelicis VenturesMetaplanetOxonian VenturesRitual CapitalY CombinatorZeno Ventures

Headspace is a mental health app that delivers personalized support through meditation, mindfulness, AI-powered guidance, coaching, therapy, and psychiatry services for individuals and organizations worldwide.

Digital HealthHealthtechMental HealthWellness & FitnessSanta Monica, US

Andy(Co-founder)Richard Marsh Pierson(Executive Officer, Director)Andrew David Puddicombe(Executive Officer, Director)Sean Brecker(Executive Officer)inScott Kriens(Director)

Co-investorsAdvance Venture PartnersBessemer Venture PartnersBreyer CapitalCity LightEniac VenturesFlucas Ventures+10 more

Hero.app provides an end-to-end revenue intelligence platform, built on its "Backstory" technology, that consolidates deal signals and account data to help revenue teams answer questions and decide next steps.

AI & Machine LearningSaaSSales Tech

Hexium develops Atomic Vapor Laser Isotope Separation (AVLIS) technology that uses lasers and electric fields to enrich isotopes, starting with lithium.

Deep TechEnergyNew MaterialsAustin, US

Leonard Charles Jarrott(Executive Officer, Director)Jacob Peterson(Executive Officer, Director)

BoardMike Palank(Director)in

Co-investorsHumba VenturesJulian CapitalMaC Venture CapitalOverture ClimateR7 Partners

Vitra develops reproductive therapies that mature eggs outside the body in a controlled environment, aiming to reduce or eliminate the hormone injections required in conventional IVF.

BiotechFemTechHealthtech

Ivana Muncie-Vasic(Founder)in

Co-investorsBreakout VenturesForeground CapitalNorth South VenturesSpacecadet VenturesBoom Capital Ventures

Kin Euphorics makes non-alcoholic functional beverages formulated with adaptogens, nootropics, and botanics intended to affect mood, brain function, and immunity.

ConsumerDirect to ConsumerWellness & Fitness

Jen Batchelor(Founder)in

Co-investorsCanaan PartnersFifty YearsMelitas Ventures LlcTrousdale VenturesTwo Culture CapitalFemale Founders

Kip Health operates a therapy service that pairs in-person therapist sessions with a private mobile app for asynchronous communication between visits, using measurement-based clinical protocols.

HealthtechSan Francisco, US

Ti Zhao(Founder)in

Co-investorsY Combinator

Knowde provides a data management platform for industrial businesses, specifically chemicals and ingredients, that uses AI to extract, structure, and harmonize fragmented master data from legacy systems.

B2B MarketplacesData & InfrastructureEnterprise Software

Ali Amin-Javaheri(CEO)inWojciech Krupa(Founder)in

Co-investorsBee PartnersCoatue ManagementMantis CapitalPoint72 VenturesSequoia CapitalTq Ventures Llc+1 more

Loyal develops therapeutics to help dogs live longer and healthier lives, focusing on canine aging research and longevity interventions for companion dogs.

BiotechHealthtechLongevity

Celine Halioua(Founder & CEO)in

Co-investorsage1Collaborative FundFirst Round CapitalFlucas VenturesKhosla VenturesMetaplanet+4 more

Lucy manufactures tobacco-free nicotine pouches in various flavors and strengths designed for consumer use.

BiotechConsumerE-commerceFoodTechLos Angeles, US

John Coogan(Founder)inSamy Hamdouche(Founder)inDavid Renteln(Founder)in

Co-investorsGreycroftRRE VenturesY CombinatorGreycroft PartnersVice Ventures

Lumindt builds its own commercial battery energy storage systems that capture surplus solar or low-cost grid energy for later use, helping commercial operations reduce operating costs and avoid peak utility rates.

CleantechEnergyHardwareSan Francisco, US

Bruno Geoly(Co-Founder)Mia Rath(Co-Founder)

Co-investorsInvariantes FundMission One Capital

Macro Oceans develops seaweed-based (kelp) feedstocks and materials as a low-carbon alternative to petroleum-based chemicals and products, building a traceable seaweed supply chain with brand, technology, and grower partners.

Advanced ManufacturingBiotechCleantechClimate TechFoodTechNew MaterialsSan Francisco, US

Matthew Perkins(Founder)in

Co-investorsHAWKTAILLOWERCARBONLowercarbon Capital

Miist develops inhaled microparticle therapies designed to deliver systemic medication to the bloodstream within about 30 seconds, targeting conditions such as migraine, pain, and nausea.

BiotechDigital HealthHealthtechMedical DevicesAlameda, US

Eric Ezerins(Cofounder & Head of Technology)inDalton Signor(Cofounder & CEO)in

Co-investorsEntrepreneur First

Modern Health provides mental health support solutions for employers with over 100 employees.

Enterprise SoftwareHealthtechHR TechMental HealthSan Francisco, US

Alyson Watson(Founder/CEO)inErica Johnson(Director)Alyson Friedensohn(Executive Officer, Director)Alyson (Friedensohn) Watson(Founder)in

Co-investors01 AdvisorsKleiner PerkinsMGV.VCNecessary VenturesY CombinatorFounders Fund

Modulo is a biotech company focused on the neuroimmune system, developing treatments for brain and central nervous system disorders.

AI & Machine LearningBiotechDeep TechLos Altos, US

Mike Horowitz(CEO & Co-founder)Justin Ichida(Co-founder)Scott Patterson(CTO & Co-founder)Nicholas Saccomano(Director)Alda Leu Dennis(Director)Alexander Scott Patterson(Director)

Co-investorsCantos VenturesHAWKTAILSpacecadet VenturesBiovergeBuilders VCInitialized Capital

BiotechWaltham, US

Brian Fiske(Executive Officer, Director)George Eliades(Executive Officer, Director)inSandra Poole(Executive Officer)Alex Nichols(Executive Officer, Director, Promoter)

BoardBryan Roberts(Director)Peter Hecht(Director)

Co-investorsHemi Ventures, LlcLifeforce CapitalVenrock Associates

NetworkOcean builds underwater and floating data center systems cooled by seawater, reducing power consumption by up to 40% and eliminating freshwater usage compared to traditional facilities.

Advanced ManufacturingAI & Machine LearningCleantechClimate TechCloud ComputingHardwareSan Francisco, US

Sam Mendel(CEO, Co-Founder)inEric Kim(CTO, Co-Founder)in

Co-investorsTranspose Platform ManagementY Combinator

Octant is a therapeutics company that develops small molecule drugs to treat protein misfolding diseases.

AI & Machine LearningBiotechDeep TechMedical DevicesEmeryville, US

Sri Kosuri(Co-founder)inRamsey Homsany(Founder)in

Co-investorsAndreessen Horowitz+ND Capital8VCCarbon SiliconCatalio Capital Management, LPFifty Years+5 more

Ophelia provides medication-assisted treatment for opioid addiction through a telemedicine platform, allowing patients to receive care without attending residential rehab.

Digital HealthHealthtechWellness & FitnessNew York City, US

Mattan Griffel(Founder)inZack Gray(Founder)inDr. Arthur Robin Williams(Codesigner)

BoardGreg Yap(Director)inDr. Adam Bisaga(Codesigner)

Co-investorsMenlo VenturesY CombinatorFour Acres CapitalGood FriendsGeneral CatalystInterplay Ventures Early Stage Management Llc+1 more

Orchid provides an electronic health record system with AI capabilities for solo and small-group mental health practices, handling administrative tasks and clinical documentation to reduce manual work.

AI & Machine LearningHealthtechSaaSSan Francisco, US

Joseph Pomianowski(Founder)in

Co-investorsY CombinatorDay One Ventures

Orchid is a personal assistant that operates via text messaging to help users with organization, information retrieval, and task completion.

AI & Machine LearningConsumerEnterprise SoftwareFuture of WorkSan Francisco, US

Nizar Abi Zaher(Founder)inAdam Wazzan(Founder)in

Co-investorsY CombinatorDay One Ventures

Orchid offers whole genome sequencing-based genetic screening of embryos during IVF as well as preconception testing for couples, analyzing DNA to identify predispositions to monogenic diseases, chromosomal abnormalities, and polygenic risks.

BiotechDigital HealthFemTechSan Francisco, US

Alexandra Meyer(President and Chief Executive Officer of Issuer)

BoardEmily Anhalt(Director of Issuer)

Co-investorsBalaji SrinivasanCarnrite VenturesHartmann CapitalPebblebed

Parallel Bio develops human immune organoids and computational tools to predict drug efficacy across diverse patient populations, replacing animal testing in drug discovery.

AI & Machine LearningBiotechDeep TechHealthtechSan Francisco, US

Robert DiFazio(Founder)inJuliana Hilliard(Founder)in

Co-investorsAIX VenturesBreakout VenturesHumba VenturesImmeasurableJulian CapitalMetaplanet+5 more

AI-powered pathology for improved patient outcomes

Boston, US

ANDREW BECK(Executive Officer, Director)inADITYA KHOSLA(Executive Officer, Director)

BoardMICHELLE DIPP(Director)STANLEY LAPIDUS(Director)JEFF LEIDEN(Director)

Co-investors8VCBIOSPRING PARTNERSFairhaven Capital PartnersGeneral CatalystNimble PartnersOrbiMed+2 more

Phytoform Labs develops GM-free genome editing tools and trait engineering technologies for crop improvement, with a focus on potato and tomato varieties.

AgTechAI & Machine LearningBiotechHarpenden, GB

William Pelton(Executive Officer, Director)Nicholas Kral(Director)Dhiraj Singh(Director)

Co-investorsBackedEniac VenturesFine Structures VenturesFTW VenturesManta Ray VenturesWireframe Ventures+1 more

PicnicHealth aggregates medical records from multiple sources and provides patients with centralized access to their health data along with AI-powered tools to understand and manage their medical information and chronic conditions.

AI & Machine LearningDigital HealthHealthtech

Noga Leviner(Co-founder)in

Co-investorsAmplify PartnersB Capital GroupB4 CapitalFelicis VenturesGreat Oaks Venture CapitalJAZZ Venture Partners+3 more

Pila makes plug-and-play home batteries that connect to a standard wall outlet to provide automatic backup power during outages and optimize household energy use, including solar charging and time-of-use bill management.

CleantechEnergyHardware

Co-investorsCity LightJetstreamXSLA VenturesR7 PartnersToyota Ventures

Co-investorsCantos VenturesSilent Ventures

Remedy Scientific decontaminates and restores environmentally compromised land using automated hardware systems combined with advanced chemistry and AI, and uses sensors to assess pollutants and tailor remediation solutions.

CleantechClimate TechRobotics

Co-investorsFloating PointCantos Ventures

Shield Bio develops nanopore sequencing technology for clinical use, designed to run rapid genetic tests in healthcare settings.

HealthtechMedical DevicesSan Francisco, US

Fred Turner(Founder/CEO)in

Co-investorsY CombinatorAndreessen HorowitzSoma CapitalValia Ventures

Smile2Impress provides invisible orthodontic treatments using clear aligner technology for patients seeking to straighten their teeth.

HealthtechMedical Devices

Co-investorsChannel 4 VenturesRedbus VenturesCAP HORN VCTrousdale Ventures