Burlingame · Seed–Series A · 3 people tracked
Also known as REFACTOR CAPITAL MANAGEMENT, LLC
Find your way into Refactor Capital
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Investment thesis
Refactor is a single-investor seed-stage firm led by Zal that writes $1-2M first checks into hard tech startups across the US. Operating as a solo capitalist managing roughly $300M across five funds, the firm aims to be a founder's first call. Its focus spans deeply technical domains including biotech and therapeutics, medical and healthcare technology, space, defense, robotics, energy and nuclear, AI infrastructure, synthetic biology and chemicals, and crypto — reflecting a broad appetite for companies 'refactoring the real world' through science and engineering.
Source: firm website, verified Sep 15, 2026.
Team · 3 people
from public directories
What they invest in
from 64 of 72 portfolio companiesBiotech ×28Healthtech ×26AI & Machine Learning ×21Deep Tech ×17Digital Health ×12Hardware ×10Climate Tech ×9Medical Devices ×8
HQs:United States×45Canada×1Spain×1United Kingdom×1Cambodia×1
Investments · 72 tracked
founders shown can be your intro pathBy year:2025 · 22024 · 22023 · 22022 · 62021 · 42019 · 22018 · 12017 · 221 dated
Coinbase is a cryptocurrency exchange platform that offers trading, custody, and financial services for cryptocurrencies, stocks, derivatives, and prediction markets to consumers, institutions, and developers.
Crypto & Web3FintechSan Francisco, US
Brian Armstrong(Co-founder & CEO)inFred Ehrsam(Co-founder)inEmilie Choi(President & COO)inAlesia Haas(Chief Financial Officer)inPaul Grewal(Chief Legal Officer & Secretary)inLawrence (L.J.) Brock(Chief People Officer)
Co-investors1confirmationA.Capital Venturesa16z cryptoAcrew CapitalAndreessen HorowitzAnsa Capital+54 more
Solugen develops a biomanufacturing platform using fermentation and bioprocessing technology to produce specialty chemicals at scale.
Advanced ManufacturingBiotechCleantechClimate TechHealthtechHouston, US
Sean Hunt(Founder/CTO)inGaurab Chakrabarti(Founder)in
BoardSeth Bannon(Director)in
Co-investorsFifty YearsFounders FundLowercarbon CapitalY CombinatorBaillie GiffordGIC+22 more
64x provides a platform and product suite for manufacturing advanced therapeutics, including gene therapies, cell therapies, and biologics.
BiotechDeep TechMedical Devices
Co-investorsBoxGroupFifty YearsFirst Round CapitalFuture VenturesLifeforce CapitalNorthpond Ventures+1 more
64x develops infrastructure and manufacturing systems for next-generation medicines, focusing on genetic engineering, cell line development, and computational biology to enable scalability of advanced therapies.
AI & Machine LearningBiotechDeep TechHealthtechMedical DevicesSan Francisco, US
Lexi Rovner(Co-founder & CEO)in
Co-investorsFifty YearsFuture VenturesLifeforce CapitalRaptor GroupY CombinatorAlix Ventures+4 more
Able Health provides software for physician organizations to administer value-based care programs, including quality measure calculation and health plan coordination to reduce administrative overhead.
HealthtechSan Francisco, US
Rachel Katz(Founder/CEO)inSteve Daniels(Founder/President)in
Co-investorsLifeforce CapitalY Combinator
Adventris is a biotechnology company developing cancer immunotherapy treatments.
BiotechHealthtechBaltimore, US
Jen Herbach(Founder)inWilliam Collis(Founder)inMark Yarchoan(Founder)
Co-investorsY CombinatorIllumina Ventures
Aether develops additives that blend into engineering-grade nylons to enable faster, high-throughput fused filament (FFF/FDM) 3D printing while maintaining mechanical strength and dimensional accuracy.
Advanced ManufacturingAI & Machine LearningBiotechDeep TechHardwareNew Materials
Pavle Jeremic(Founder & CEO)inJay Zaveri(Co-Founder & President)
Co-investors4DX VenturesAbstract VenturesArtis VenturesBlue Bear VenturesBoxGroupCalm Ventures+9 more
AKASA provides generative AI solutions for healthcare revenue cycle management, helping health systems automate administrative workflows and reduce costs.
AI & Machine LearningEnterprise SoftwareHealthtech
Malinka Walaliyadde(CEO, Co-founder, and Board Member)inBen Beadle-Ryby(Chief Revenue Officer, Co-founder, and Board Member)inAndy Atwal(Vice President of R&D Special Projects and Co-founder)inVarun Ganapathi, Ph.D.(Co-founder and Advisor)
Co-investorsAndreessen HorowitzCoatue ManagementFounders Circle CapitalBalaji SrinivasanPreface Ventures
Astranis manufactures small, high-powered geosynchronous satellites equipped with advanced digital processing technology for global telecommunications and connectivity services.
Advanced ManufacturingDeep TechHardwareSpace TechSan Francisco, US
John Gedmark(Founder/CEO)inRyan McLinko(Founder/CTO)in
Co-investorsAndreessen HorowitzBlack FlagBoxGroupCantos VenturesCherubic VenturesCommonweal Ventures+38 more
A wearable device company developing brain-sensing technology using nanotechnology for consumer use.
Deep TechHardwareHealthtech
Co-investorsAccelCompoundVery Serious VenturesBlackRockLocalGlobeNorthzone+1 more
Avail is a modular blockchain infrastructure project building a data availability layer and unification stack for rollups.
Anurag Arjun(Founder)in
Co-investorsAmino CapitalCoatue ManagementJuniperoCyber CapitalFigmentFounders Fund+1 more
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Berkeley Yeast develops genetically engineered yeast strains for the fermented beverages industry, offering improved flavor control, scalability, and consistency while reducing resource and energy consumption.
BiotechFoodTechBerkeley, US
Charles Denby(Founder)in
Co-investorsDYDX CapitalAnterra Capital
Betty Labs built Locker Room, a live audio app for sports fans, and was acquired by Spotify in March 2021.
Co-investorsScript Capital
The company builds "Biological Adapters" that integrate living neurons with AI foundation models to improve performance and reduce training cost, and it operates an algorithm discovery platform based on principles from biological neural systems.
AI & Machine LearningBiotechDeep Tech
Co-investorsBanyan VenturesPrimary Venture PartnersWonder VenturesE1 Ventures
BioRender is a software tool that enables scientists to create and share professional scientific illustrations and figures.
BiotechEdTechEnterprise SoftwareSaaSToronto, CA
Ryan Marien(Founder)inKatya Shteyn(Founder)inShiz Aoki(CEO and Co-founder)in
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Co-investorsY CombinatorFifty YearsFundersClubStandard CapitalZeno Ventures
Los Angeles, US
Charles Mason(Executive Officer, Director)
Co-investorsBlockchain CoinvestorsPantera CapitalChapter One
Brelle develops a modular energy platform for high-performance machines, combining battery hardware, embedded AI-enabled software, and automated manufacturing.
Deep TechEnergyHardwareLos Alamitos, US
Martin Hermez(Founder)Nachiket V(Founder)
Co-investorsFirst Star Ventures
Causal Labs builds a Large Physics foundation Model to learn causality through physics and weather observations.
AI & Machine LearningDeep TechSan Francisco, US
Dar Mehta(Founder)inYue (Kelsie) Zhao(Founder)
Co-investorsKindred VenturesTranspose Platform ManagementBoxGroupKarman VenturesOtherwise
Checkerspot uses microalgae precision fermentation to produce specialized lipids and fats, including a bio-equivalent source of the sn-2 palmitate fat found in mother's milk, rare bioactive fatty acids, and tropical fat alternatives.
BiotechClimate TechFoodTechNew MaterialsAlameda, US
Scott Franklin(Executive Officer, Director)inCharles Dimmler(Executive Officer, Director)inJohn Krzywicki(CEO)inLayla Ward(CFO)inCasey Lippmeier(CTO)inLeon Parker(SVP, Molecular Biology)in
Co-investorsBaruch Future VenturesBreakout VenturesCavallo VenturesBuilders VCKdT Ventures
Clover Health is a health insurance provider offering low-cost plans with minimal premiums, copays, and prescription drug costs.
Digital HealthHealthtechInsurTechJersey City, US
Vivek Garipalli(Executive Officer, Director)inAndrew ToyinKris Gale(Executive Officer, Director)
BoardNat Turner(Director)inMike Dixon(Director)Josh Kopelman(Director)in
Co-investorsFirst Round CapitalFloodgateGV (Google Ventures)Lifeforce CapitalToba CapitalSequoia Capital+1 more
Curative offers an employer-sponsored health insurance plan with $0 copays, $0 deductibles, and a single monthly premium, giving members access to a nationwide provider network, telehealth, and $0 preferred prescriptions.
Digital HealthHealthtechInsurTechAustin, US
Isaac Turner(Founder)inFrederick Edward Turner(Executive Officer, Director)Tami Denise Wilson-Ciranna(Chief Financial Officer)
Co-investorsDCVC (Data Collective)Jam FundUndeterred Capital
Enzyme develops a Quality Management System (QMS) software platform for life science companies including drug, biologic, device, and digital product manufacturers, designed to streamline regulatory workflows and generate FDA-ready documentation.
Enterprise SoftwareHealthtechMedical DevicesSaaSSan Francisco, US
Jared Seehafer(Founder/CEO)inJacob Graham(Founder/Vice President QA/RA)in
Co-investorsY CombinatorAg Startup Engine SeedSahsen Ventures
Epana Bio develops therapies for autoimmune diseases by leveraging genomics and AI to identify and target cellular origins of disease, with a focus on precision medicine for patient populations.
AI & Machine LearningBiotechDigital Health
Co-investorsBreakout LabsBreakout VenturesHAWKTAILHummingbird VenturesOMX VenturesKdT Ventures
Evernow provides virtual menopause care for women, offering one-time video visits and ongoing membership access to certified menopause providers who prescribe hormone therapy and estrogen replacement.
Digital HealthFemTechWellness & Fitness
Alicia Jackson(Founder)in
Co-investorsNew Enterprise Associates (NEA)8VCCoelius Capital
Xometry provides an instant quoting and manufacturing platform that connects startups and enterprises with a global network of manufacturers to produce precision components from prototype through high-volume production.
Advanced ManufacturingB2B MarketplacesSaaS
Co-investorsAugust CapitalMaryland TEDCOTEDCO
Floodbase offers a parametric insurance platform that uses flood data and near real-time flood event monitoring to help insurers design, price, underwrite, and trigger flood coverage.
AI & Machine LearningClimate TechData & InfrastructureInsurTechBrooklyn, US
Bessie Schwarz(Co-founder)inBeth Tellman(Co-founder)in
BoardMarty Schneider(Director)Sasha Brown(Director)John Loser(Director)in
Co-investorsBURNT ISLAND VENTURESEcosystem Integrity FundFloating PointGroundForce CapitalLOWERCARBONLowercarbon Capital+4 more
From Yellow To Orange (fyto) is a Japanese company that produces and distributes music and video, composes and arranges music, and plans, develops, and sells games and digital content.
ConsumerGamingMedia & EntertainmentPetaluma, US
Kenji Eno(Founder)Yuka Iino(Representative Director (CEO))Jason Prapas(Executive Officer, Director)Harold Kruth(Director)Andy Wheeler(Director)
Co-investorsAgFunderFirst Star VenturesGV (Google Ventures)
Fyto develops nutrient recycling and protein production technology for farmers, enabling sustainable food production with reduced environmental impact.
AgTechClimate TechFoodTechRoboticsSan Francisco Bay Area, US
Jason Prapas(Founder)
Co-investorsCity LightAgFunderBaukunstFirst Star VenturesGV (Google Ventures)
Gencove provides direct-to-consumer genetic sequencing and polygenic risk scoring for health insights.
BiotechDigital HealthHealthtechNew York, US
Tomaz Berisa(Executive Officer, Director)inJoseph Pickrell(Executive Officer, Director)in
BoardSara Eshelman(Director)in
Co-investorsBread And Butter Ventures, LlcSpero VenturesBalaji SrinivasanThird Kind Venture CapitalVersion One Ventures
General Galactic is a space infrastructure company focused on building orbital and extraterrestrial infrastructure, drawing inspiration from science fiction concepts like propellant generation for off-Earth settlement.
Deep TechHardwareLogistics & Supply ChainSpace TechEl Segundo, US
Halen Mattison(Cofounder)inLuke Neise(Cofounder)in
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Co-investorsAntiHarpoon VenturesPathbreaker VenturesSeraphim SpaceUnruly Capital
Granza Bio develops immunotherapy treatments leveraging naturally-occurring attack particles that are released from cytotoxic immune cells to target diseases including cancers, autoimmunity, and infections.
BiotechDeep TechDigital HealthHealthtechSan Francisco, US
Prof. DustinAshwin Nandakumar(Founder)inAshwin Jainarayanan(Founder)inAshwin Menon Nandakumar(Founder)in
Co-investorsFelicis VenturesMetaplanetOxonian VenturesRitual CapitalY CombinatorZeno Ventures
Headspace is a mental health app that delivers personalized support through meditation, mindfulness, AI-powered guidance, coaching, therapy, and psychiatry services for individuals and organizations worldwide.
Digital HealthHealthtechMental HealthWellness & FitnessSanta Monica, US
Andy(Co-founder)Richard Marsh Pierson(Executive Officer, Director)Andrew David Puddicombe(Executive Officer, Director)Sean Brecker(Executive Officer)in
BoardScott Kriens(Director)
Co-investorsAdvance Venture PartnersAdvancit CapitalBessemer Venture PartnersBreyer CapitalCity LightEniac Ventures+14 more
A revenue intelligence platform that provides deal context, risk visibility, and marketing attribution to help sales and revenue teams win more deals.
AI & Machine LearningMarketing TechSaaSSales Tech
Co-investorsZillionize
Hexium develops Atomic Vapor Laser Isotope Separation (AVLIS) technology that uses lasers and electric fields to enrich isotopes, starting with lithium.
Deep TechEnergyNew MaterialsAustin, US
Leonard Charles Jarrott(Executive Officer, Director)Jacob Peterson(Executive Officer, Director)in
BoardMike Palank(Director)in
Co-investorsHumba VenturesJulian CapitalMaC Venture CapitalOverture ClimateR7 Partners
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Vitra Bio is a biotechnology company developing technology aimed at transforming fertility treatment.
BiotechFemTechHealthtech
Ivana Muncie-Vasic(Chief Executive Officer and Founder)inJohn Langowski(Chief Technology Officer)in
Co-investorsBreakout VenturesForeground CapitalNorth South VenturesSpacecadet VenturesBoom Capital Ventures
Kin Euphorics makes non-alcoholic functional beverages formulated with adaptogens, nootropics, and botanics intended to affect mood, brain function, and immunity.
ConsumerDirect to ConsumerWellness & Fitness
Jen Batchelor(Founder)in
Co-investorsCanaan PartnersFifty YearsMelitas Ventures LlcTrousdale VenturesTwo Culture CapitalFemale Founders
Kip Health operates a therapy service that pairs in-person therapist sessions with a private mobile app for asynchronous communication between visits, using measurement-based clinical protocols.
HealthtechSan Francisco, US
Co-investorsY Combinator
Knowde provides a data management platform for industrial businesses, specifically chemicals and ingredients, that uses AI to extract, structure, and harmonize fragmented master data from legacy systems.
B2B MarketplacesData & InfrastructureEnterprise Software
Ali Amin-Javaheri(CEO)inWojciech Krupa(Founder)in
Co-investorsBee PartnersCoatue ManagementMantis CapitalPoint72 VenturesSequoia CapitalTq Ventures Llc+1 more
Loyal develops longevity drugs for dogs, targeting the biological processes of aging to extend healthy lifespan and reduce age-associated disease.
BiotechHealthtechLongevity
Celine Halioua(Founder & CEO)in
Co-investorsage1Collaborative FundFirst Round CapitalFlucas VenturesInvariantes FundKhosla Ventures+9 more
Lucy manufactures tobacco-free nicotine pouches in various flavors and strengths designed for consumer use.
BiotechConsumerE-commerceFoodTechLos Angeles, US
John Coogan(Founder)inSamy Hamdouche(Founder)inDavid Renteln(Founder)in
Co-investorsGreycroftRRE VenturesY CombinatorGreycroft PartnersVice Ventures
Lumindt builds its own commercial battery energy storage systems that capture surplus solar or low-cost grid energy for later use, helping commercial operations reduce operating costs and avoid peak utility rates.
CleantechEnergyHardwareSan Francisco, US
Bruno Geoly(Co-Founder)Mia Rath(Co-Founder)
Co-investorsInvariantes FundMission One Capital
Macro Oceans develops seaweed-based (kelp) feedstocks and materials as a low-carbon alternative to petroleum-based chemicals and products, building a traceable seaweed supply chain with brand, technology, and grower partners.
Advanced ManufacturingBiotechCleantechClimate TechFoodTechNew MaterialsSan Francisco, US
Matthew Perkins(Founder)in
Co-investorsHAWKTAILLOWERCARBONLowercarbon Capital
Miist develops inhaled microparticle therapies designed to deliver systemic medication to the bloodstream within about 30 seconds, targeting conditions such as migraine, pain, and nausea.
BiotechDigital HealthHealthtechMedical DevicesAlameda, US
Eric Ezerins(Cofounder & Head of Technology)inDalton Signor(Cofounder & CEO)in
Co-investorsEntrepreneur First
Modern Health provides mental health support solutions for employers with over 100 employees.
Enterprise SoftwareHealthtechHR TechMental HealthSan Francisco, US
Alyson Watson(Founder/CEO)inErica Johnson(Director)Alyson Friedensohn(Executive Officer, Director)inAlyson (Friedensohn) Watson(Founder)in
Co-investors01 AdvisorsKleiner PerkinsMGV.VCNecessary VenturesY CombinatorFounders Fund
Modulo is a biotech company focused on the neuroimmune system, developing treatments for brain and central nervous system disorders.
AI & Machine LearningBiotechDeep TechLos Altos, US
Mike Horowitz(CEO & Co-founder)Justin Ichida(Co-founder)inScott Patterson(CTO & Co-founder)inJoe Wagner(Chief Development Officer)
BoardAlda Leu Dennis(Director)inNicholas Saccomano(Director)
Co-investorsCantos VenturesHAWKTAILSpacecadet VenturesBiovergeBuilders VCInitialized Capital
BiotechWaltham, US
Brian Fiske(Executive Officer, Director)George Eliades(Executive Officer, Director)inSandra Poole(Executive Officer)inAlex Nichols(Executive Officer, Director, Promoter)
BoardBryan Roberts(Director)inPeter Hecht(Director)
Co-investorsHemi Ventures, LlcLifeforce CapitalVenrock Associates
NetworkOcean builds underwater and floating data center systems cooled by seawater, reducing power consumption by up to 40% and eliminating freshwater usage compared to traditional facilities.
Advanced ManufacturingAI & Machine LearningCleantechClimate TechCloud ComputingHardwareSan Francisco, US
Sam Mendel(CEO, Co-Founder)inEric Kim(CTO, Co-Founder)in
Co-investorsTranspose Platform ManagementY Combinator
Octant is a therapeutics company that develops small molecule drugs to treat protein misfolding diseases.
AI & Machine LearningBiotechDeep TechMedical DevicesEmeryville, US
Sri Kosuri(Co-founder)inRamsey Homsany(Founder)in
Co-investorsAndreessen Horowitz+ND Capital8VCCarbon SiliconCatalio Capital Management, LPFifty Years+5 more
Ophelia provides medication-assisted treatment for opioid addiction through a telemedicine platform, allowing patients to receive care without attending residential rehab.
Digital HealthHealthtechWellness & FitnessNew York City, US
Mattan Griffel(Founder)inZack Gray(Founder)inDr. Arthur Robin Williams(Codesigner)
BoardGreg Yap(Director)inDr. Adam Bisaga(Codesigner)
Co-investorsMenlo VenturesY CombinatorFour Acres CapitalGood FriendsGeneral CatalystInterplay Ventures+2 more
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Orchid provides an electronic health record system with AI capabilities for solo and small-group mental health practices, handling administrative tasks and clinical documentation to reduce manual work.
AI & Machine LearningHealthtechSaaSSan Francisco, US
Joseph Pomianowski(Founder)in
Co-investorsY CombinatorDay One Ventures
Orchid is a personal assistant that operates via text messaging to help users with organization, information retrieval, and task completion.
AI & Machine LearningConsumerEnterprise SoftwareFuture of WorkSan Francisco, US
Nizar Abi Zaher(Founder)inAdam Wazzan(Founder)in
Co-investorsHartmann CapitalY CombinatorDay One Ventures
Orchid Hospital operates two healthcare facilities in Phnom Penh, Cambodia, providing specialized obstetrics, gynecology, pediatrics, maternity care, and general medical services.
HealthtechMedical DevicesPhnom Penh, KH
Co-investorsNavis Capital PartnersDay One VenturesIntel CapitalPebblebedTeam8
Orchid offers whole genome sequencing-based genetic screening of embryos during IVF as well as preconception testing for couples, analyzing DNA to identify predispositions to monogenic diseases, chromosomal abnormalities, and polygenic risks.
BiotechDigital HealthFemTechSan Francisco, US
Alexandra Meyer(President and Chief Executive Officer of Issuer)
BoardEmily Anhalt(Director of Issuer)
Co-investorsBalaji SrinivasanCarnrite VenturesHartmann CapitalPebblebed
Parallel Bio develops human immune organoids and computational tools to predict drug efficacy across diverse patient populations, replacing animal testing in drug discovery.
AI & Machine LearningBiotechDeep TechHealthtechSan Francisco, US
Robert DiFazio(Founder)inJuliana Hilliard(Founder)in
Co-investorsAIX VenturesBreakout VenturesHumba VenturesImmeasurableJulian CapitalMetaplanet+5 more
AI-powered pathology for improved patient outcomes
Boston, US
ANDREW BECK(Executive Officer, Director)inADITYA KHOSLA(Executive Officer, Director)
BoardMICHELLE DIPP(Director)STANLEY LAPIDUS(Director)JEFF LEIDEN(Director)
Co-investors8VCBIOSPRING PARTNERSFairhaven Capital PartnersGeneral CatalystNimble PartnersOrbiMed+2 more
Phytoform Labs develops GM-free genome editing tools and trait engineering technologies for crop improvement, with a focus on potato and tomato varieties.
AgTechAI & Machine LearningBiotechHarpenden, GB
William Pelton(Executive Officer, Director)inNicholas Kral(Director)Dhiraj Singh(Director)
Co-investorsBackedEniac VenturesFine Structures VenturesFTW VenturesManta Ray VenturesWireframe Ventures+1 more
PicnicHealth aggregates medical records from multiple sources and provides patients with centralized access to their health data along with AI-powered tools to understand and manage their medical information and chronic conditions.
AI & Machine LearningDigital HealthHealthtech
Noga Leviner(Co-founder)in
Co-investorsAmplify PartnersB Capital GroupB4 CapitalFelicis VenturesGreat Oaks Venture CapitalJAZZ Venture Partners+3 more
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Pila manufactures home battery systems with mesh-networking capabilities for backup power and energy storage, enabling homeowners to store and manage solar and grid electricity while monitoring appliance usage through an app-based platform.
CleantechClimate TechEnergyHardwareIoT
Co-investorsCity LightJetstreamXSLA VenturesGS FuturesR7 PartnersToyota Ventures
Software platform to improve drug discovery
AI & Machine LearningBiotechDeep TechNew York, US
David William Rooklin(Executive Officer, Director)Haotian Li(Director)
Co-investorsHAWKTAILNotation CapitalAcequia Capital (AceCap)Collaborative FundPreface VenturesThird Kind Venture Capital+1 more
Remedy Scientific decontaminates and restores environmentally compromised land using automated hardware systems combined with advanced chemistry and AI, and uses sensors to assess pollutants and tailor remediation solutions.
CleantechClimate TechRobotics
Co-investorsFloating PointCantos Ventures
Shield Bio develops nanopore sequencing technology for clinical use, designed to run rapid genetic tests in healthcare settings.
HealthtechMedical DevicesSan Francisco, US
Fred Turner(Founder/CEO)in
Co-investorsY CombinatorAndreessen HorowitzSoma CapitalValia Ventures
Smile2Impress provides invisible orthodontic treatments using clear aligner technology for patients seeking to straighten their teeth.
HealthtechMedical Devices
Co-investorsChannel 4 VenturesRedbus VenturesCAP HORN VCTrousdale Ventures
Spora discovers and cultivates wild fungal strains from pristine ecosystems, processing them with proprietary biotechnology and nanotechnology to create mycelium-based products.
BiotechCircular EconomyDeep TechNew Materials
Co-investorsCapria VenturesHeadwater VenturesHuman VenturesM13MaC Venture CapitalTechstars
The Biological Computing Co. uses living neurons to study how biological systems process information and applies those insights to improve AI model training and inference.
AI & Machine LearningBiotechDeep TechHardware
Co-investors8VCCraft VenturesFounders FundPrimary VenturesSequoia CapitalValor Equity Partners+1 more
Thalolabs provides two connected products for HVAC companies: a diagnostic tool that automates installation commissioning workflows, and a monitoring device that tracks system health and performance over time.
Advanced ManufacturingAI & Machine LearningClimate TechEnterprise SoftwareHardwareIoT
Dr. Brendan Hermalyn(Founder and CEO)
Co-investorsGigascale CapitalVery Serious VenturesVirta VenturesSuffolk TechnologiesThird Sphere
Trace Genomics, now part of Miraterra, provides soil analysis and genomic sequencing to give growers and agronomists insights on nutrients and pathogens across more than 70 crops and 225+ pathogens.
AgTechAI & Machine LearningBiotechBurlingame, US
Poornima Parameswaran(Executive Officer, Director)Diane Wu(Executive Officer, Director)Michael Toelle(Director)Joe Pianelli(Director)William Buckner(Director)
Co-investorsBeast VenturesOspraie Ag ScienceS2G InvestmentsWP Global PartnersFall Line CapitalRabo Ventures
Vital provides an AI-driven patient experience product for hospital emergency departments that uses real-time EHR data to predict wait times, explain lab results and notes in plain language, and turn discharge instructions into a checklist accessed via a password-less text link.
AI & Machine LearningDigital HealthHealthtechSaaS
Co-investorsThreshold Ventures
YourChoice Therapeutics is developing YCT-529, a non-hormonal oral contraceptive for men currently in Phase 2 clinical trials.
BiotechFemTechHealthtech
Akash Bakshi, MSc(Co-founder & CEO)Nadja Mannowetz, PhD(Co-founder & CSO)
Co-investorsBlue Bear VenturesCivilization Ventures Management, LlcForeground CapitalFuture VenturesNorth South VenturesPortfolia+1 more
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
TL BiolabsAngie's ListPilgrimTempest
Exits · 6
2 IPOs · 4 acquisitions · showing 1CoinbaseNasdaq: COIN
Portfolio news
latest coverage across their companiesCoinbase · investing.com · Aug 31, 2026
Atlas · pulse2.com · Jul 18, 2026
Astranis · thenextweb.com · Jul 16, 2026
64x Bio · businesswire.com · Jun 29, 2026
Floodbase · coverager.com · May 29, 2026
Thalo · pulse2.com · May 20, 2026
Orchid · finance.yahoo.com · Apr 29, 2026
Frequently asked questions
- How many investments has Refactor Capital made?
- Refactor Capital has 72 tracked investments, 6 of which have exited, including 3 dated in the last 24 months.
- What stage does Refactor Capital invest at?
- Refactor Capital invests at the Seed, Series A stages.
- What is Refactor Capital's typical check size?
- Refactor Capital typically writes checks of $1M – $2M.
- What sectors does Refactor Capital focus on?
- Refactor Capital focuses on AgTech, AI & Machine Learning, Biotech, Climate Tech, Crypto & Web3, Deep Tech, Defense Tech, Energy, FemTech, Fintech, Hardware, Healthtech, InsurTech, Medical Devices, Mental Health, New Materials, Robotics, Space Tech.
- Where is Refactor Capital located?
- Refactor Capital is headquartered in Burlingame, US.
- Does Refactor Capital lead rounds?
- Yes, Refactor Capital leads investment rounds.
- Who does Refactor Capital co-invest with?
- Refactor Capital most often shares deals with Y Combinator, Greycroft, Kleiner Perkins, among 7 tracked co-investors.
Media · Podcasts & interviews
featuring the teamRefactor Capital: David Lee "The Importance of Market Timing" [Hashed Interview_해시드 인터뷰]
#Hashed · David Lee
Images
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Co-investors · 55
Fifty Years (50Y) is a pre-seed and seed-focused venture capital firm that backs founders using technology to solve major global problems, and also helps start companies.
Andreessen Horowitz (a16z) is a venture capital firm founded in 2009 by Marc Andreessen and Ben Horowitz, known for pioneering the platform model with a large team of operators supporting founders across stages.
BoxGroup is an early-stage venture capital firm that invests in startups at their earliest stages.
Cantos Ventures is an early-stage venture firm founded in 2016 that provides initial capital and ongoing counsel to founders building deep technology in areas such as robotics, energy, space, defense, and advanced manufacturing.
Founders Fund is a venture capital firm that backs technology companies building transformative products.
First Round Capital is an early-stage venture firm that backs companies at their earliest moments, often before they are named, across enterprise, AI, consumer, healthcare, fintech and hardware sectors.
Sequoia Capital is a venture capital firm that partners with founders to build technology companies.
Khosla Ventures is a venture capital firm founded by Vinod Khosla.
Liquid 2 is an early- and growth-stage venture capital firm that invests in founders across all sectors of technology, providing capital along with support from a network of operators.
Lux Capital is a venture capital firm that backs founders building transformative deep technologies, having been among the first investors in category-defining companies across AI, robotics, biotech, defense, and infrastructure.
Kindred Ventures is a San Francisco-based venture capital firm that backs technology startups in their earliest financing rounds, often helping form and fund companies before they exist. It has backed 100+ startups.
▶43 more co-investors
UpHonest CapitalAmplify PartnersSoma CapitalVenrockBlockchain CapitalThreshold VenturesHelium-3 VenturesCompoundBee PartnersValia Venturesage1Index VenturesAlumni VenturesBenchmarkFJ LabsKrakenNorwest Venture PartnersAtomicoSOSVSusa VenturesOffline VenturesMayfield FundBuckley Ventures Management Company LlcHack VCOperator LPArray Ventures Management LlcFormation GroupHighbury HoldingsWormhole CapitalVerified CapitalIncite.orgMoving Capital8090 IndustriesArkitekt VenturesFactorial CapitalFrialeIndustry VenturesMeridian Street CapitalTencent HoldingsCloudflare, Inc.Ahren Innovation CapitalMoonstone Venture CapitalTeam Builder Ventures
Firms observed investing alongside Refactor Capital, from public investor directories. Shared companies are the overlap with Refactor Capital's recorded portfolio.
Similar investors
Everywhere Ventures is an early-stage venture firm, backed by a community of founders and operators as LPs, that writes early checks (including pre-seed) into startups across many sectors and geographies.
Khosla Ventures is a venture capital firm founded by Vinod Khosla.
DCVC (Data Collective) is a deep tech venture capital firm that backs entrepreneurs using computational approaches to solve large-scale real-world problems across many industries.
Unruly Capital is a venture firm that backs founders working on ideas that seem too early or unconventional but are expected to become mainstream within a decade, focusing on frontier technology themes.
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