How many investments has Spruce Capital Partners made?

Spruce Capital Partners has 10 tracked investments.

What stage does Spruce Capital Partners invest at?

Spruce Capital Partners invests at the Series A, Series B, Growth stages.

Where is Spruce Capital Partners located?

Spruce Capital Partners is headquartered in South San Francisco, US.

Who does Spruce Capital Partners co-invest with?

Spruce Capital Partners most often shares deals with Prelude Ventures, Breakthrough Energy Ventures, DCVC (Data Collective), among 29 tracked co-investors.

Spruce Capital Partners

Venture capitaloperating company · company profile

South San Francisco · Series A–Growth · 3 people tracked

Also known as SPRUCE CAPITAL PARTNERS LLC

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Investment thesis

Spruce Capital Partners focuses on the life sciences sector, backing companies that generate positive environmental impact while advancing human health and wellness. Beyond providing capital, the firm takes an active role by creating and advising companies, indicating a hands-on approach that spans company formation, guidance, and investment.

Invests inBiotech Climate Tech Digital Health Healthtech Medical Devices Wellness & Fitness South San Francisco United States

Source: firm website, verified Aug 25, 2026.

Stage

Series A–Growth

South San Francisco, California, US

Instruments

Equity

Founded

2013

Last 12 months

1 investment

Private fund assets

$116.6M

VC funds

Tracked investments

Team · 3 people

from the firm's website

Ganesh Kishore· Managing Partner· Singapore, Singaporein

Ganesh Kishore is a co-founder and Managing Partner at Spruce Capital Partners, with a background in biotechnology research, development, and business. He earned a Ph.D. in biochemistry from the Indian Institute of Science and completed postdoctoral training at the University of Texas at Austin. His earlier career included roles at Monsanto (where he contributed to Roundup Ready technology and Aspartame synthesis and led its Nutrition & Consumer Sector), Chief Technology Officer of Agriculture & Nutrition and later Chief Biotechnology Officer at DuPont, and CEO of the Malaysian Life Science Capital Fund.

k•••@sprucecp.comreveal

Roger Wyse· Managing Partner· Austin, Texas, United Statesin

Roger Wyse is co-founder and Managing Partner at Spruce Capital Partners, which he helped launch in 2013. He previously spent time at Burrill & Company from 1998 to 2013, where he served as President and COO of Biogreentech and led its agriculture, food, nutraceuticals, and industrial biotech venture activities. His earlier career included roles as Dean of the College of Agricultural and Life Sciences at the University of Wisconsin-Madison, Dean of Research at Cook College at Rutgers University, and 15 years as a scientist with the USDA-ARS.

r•••@sprucecp.comreveal

Greg Young· Managing Partner

Greg Young is a Managing Partner and co-founder of Spruce Capital Partners, with over eighteen years of experience in biotechnology. He previously served as a Managing Director at Burrill & Company, a financial services firm focused on the life sciences, and earlier worked as a molecular biologist specializing in protein expression at a San Diego biotech startup. His investment focus includes agriculture, renewable energy, chemicals, and biological tools that support sustainability. He holds a BS in Biochemistry and Cell Biology from UC San Diego and an MS in Biotechnology from Northwestern University.

g•••@sprucecp.comreveal

What they invest in

from 10 of 12 portfolio companies

AgTech ×6Biotech ×6AI & Machine Learning ×2Healthtech ×2Climate Tech ×1Deep Tech ×1Digital Health ×1FemTech ×1

HQs:United States×8

Investments · 12 tracked

founders shown can be your intro path

By year:2026 · 1 2023 · 1 2021 · 1 2015 · 14 dated

Amfora Inc.Feb 2021SEC filingmedium confidence

BiotechSan Francisco, US

Lloyd Kunimoto(Executive Officer, Director)

BoardLindsay Adler(Director)

Board seatRoger WyseGanesh Kishore· per SEC Form D · $8.3M raise · filed Feb 2021

Infinant Healthinfinanthealth.com in 𝕏Jun 2026SEC filingmedium confidence

Infinant Health develops probiotic products based on B. infantis strains that work with breast milk to support the infant gut microbiome, including its INF108 drug strain aimed at preventing necrotizing enterocolitis (NEC) in premature infants.

BiotechDigital HealthFemTechHealthtechWellness & FitnessSacramento, US

J. Bruce German(Co-founder)David Mills(Co-founder)Carlito Lebrilla(Co-founder)Daniela Barile(Co-founder)Samara Freeman(Co-founder & Director of Intellectual Property and Regulatory Affairs)Michael Johnson(Executive Officer, Director)

Board seatRoger Wyse· per SEC Form D · $118.2M raise · filed Jun 2026

Co-investorsAcre Venture Partners Bow Capital Horizons Ventures iSelect Fund Longitude Capital Bill & Melinda Gates Foundation

Inscriptainscripta.comJun 2023

BiotechBoulder, US

Michael Graige(Executive Officer)Ron McGrath(Executive Officer)Sri Kosaraju(Executive Officer, Director)Dianna L. DeVore(Executive Officer)

BoardBryan Roberts(Director)

Board seatRoger Wyse· per SEC Form D

Co-investorsForesite Capital iGlobe Partners Korys Oak HC/FT OMX Ventures Paladin Capital Group +3 more

Agerpointagerpoint.com in 𝕏

Agerpoint provides an AI-powered field intelligence platform that combines smartphone scans, LiDAR, satellite imagery, drones, sensors, and connected equipment data to analyze crops, trees, and field conditions in production agriculture.

AgTechAI & Machine LearningClimate TechOrlando, US

K. Thomas McPeek(Executive Officer, Director, Promoter)Kevin Lang(CEO & President)Michael Gomes(VP & GM, Intelligent Equipment)Gary Rudolph(VP, Engineering)Mike Batesole(CFO)

Co-investorsCultivation Capital

Amforaincamforainc.com

Consumer Physicsconsumerphysics.com in 𝕏

Consumer Physics (SCiO) makes a handheld near-infrared spectroscopy scanner paired with a database of molecular signatures to analyze the chemical composition of physical materials.

AgTechAI & Machine LearningDeep TechFoodTechHardwareHerzliya

Damian Goldring(Executive Officer)Dror Sharon(Executive Officer, Director)Haiyin Shen(Director)William Rosenzweig(Director)

BoardBenny Buller(Director)

Co-investorsXeraya Capital Khosla Ventures OurCrowd

Crop Enhancementcrop-enhancement.com

Crop Enhancement develops CropCoat, a nontoxic crop treatment that leaves no residue on the harvested crop, aimed at agricultural growers.

AgTechNew Materials

Co-investors1955 Capital Bandgap Ventures Phoenix Venture Partners

Evolve Biosystemsevolvebiosystems.com in 𝕏Jul 2015

Evolve Biosystems develops probiotic strains of B. infantis, including EVC001 and a next-generation drug strain INF108, aimed at supporting the infant gut microbiome and preventing necrotizing enterocolitis (NEC) in premature infants.

BiotechHealthtechMedical DevicesDavis, US

J. Bruce German(Director)David Mills(Executive Officer)David J. Kyle(Executive Officer, Director)John Campbell(Executive Officer)James Campbell(Executive Officer)

BoardDaniel Janney(Director)

Co-investorsiSelect Fund

GreenLight Biosciencesgreenlightbiosciences.com in

GreenLight Biosciences develops RNA-based solutions for agriculture and pest control, including a Colorado potato beetle bio-insecticide and a Varroa destructor mite-control product for sustainable food production.

AgTechBiotechImpact & Social GoodMedford, US

Andrey Zarur(Executive Officer, Director)inMarta Ortega-Valle(Executive Officer)William Blake(Executive Officer)

BoardDavid Furneaux(Director)Jonathan Fleming(Director)James Swartz(Director)

Co-investorsFuture Ventures Lewis & Clark Ventures Prelude Ventures S2G Investments Fall Line Capital

Mlscfmlscf.com

Pivot Biopivotbio.com in 𝕏

Pivot Bio develops agricultural innovations focused on transforming farming practices through microbiology and genetics.

AgTechBiotechEmeryville, US

Alvin Tamsir(Executive Officer, Director)Karsten Temme(Executive Officer, Director)

BoardRoger Wyse(Director)inJohn Hamer(Director)inMatt Ocko(Director)in

Co-investorsBreakthrough Energy Ventures Congruent Ventures DCVC (Data Collective)G2 Venture Partners K3 Ventures Manta Ray Ventures +5 more

Proviviprovivi.com in 𝕏

AgTechSanta Monica, US

Frances Arnold(Director)Peter Meinhold(Executive Officer)Pedro Coelho(Executive Officer)Corey Huck(Executive Officer, Director)

BoardGANESH KISHORE(Director)inALAN BOYCE(Director)

Co-investorsAliment Capital Kairos Venture Investments, Llc Pontifax AgTech Vivo Capital Kairos Venture Partners Xeraya Capital

Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.

Portfolio news

latest coverage across their companies

Agerpoint Awarded Meta AI Glasses Impact Grant to Advance Hands-Free Intelligence for Agricultural Fieldwork

Agerpoint · prnewswire.com · Jul 29, 2026

Infinant Health has filed a notice of an exempt offering of securities to raise $118,230,513.00 in New Funding. - intelligence360

Infinant Health · intelligence360.news · Jul 21, 2026

Pivot Bio Celebrates America 250 with Patriotic Brand Takeover and Summer of Gratitude | Pivot Bio

Pivot Bio · pivotbio.com · Jul 1, 2026

Trysignalbase

Provivi · trysignalbase.com · Jun 11, 2026

Striving to Commercialize CRISPR, Inscripta Lands $55M | Chief Healthcare Executive

Inscripta · chiefhealthcareexecutive.com · Jan 8, 2026

Frequently asked questions

How many investments has Spruce Capital Partners made?: Spruce Capital Partners has 10 tracked investments.
What stage does Spruce Capital Partners invest at?: Spruce Capital Partners invests at the Series A, Series B, Growth stages.
What sectors does Spruce Capital Partners focus on?: Spruce Capital Partners focuses on Biotech, Climate Tech, Digital Health, Healthtech, Medical Devices, Wellness & Fitness.
Where is Spruce Capital Partners located?: Spruce Capital Partners is headquartered in South San Francisco, US.
Who does Spruce Capital Partners co-invest with?: Spruce Capital Partners most often shares deals with Prelude Ventures, Breakthrough Energy Ventures, DCVC (Data Collective), among 29 tracked co-investors.

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