What stage does Spruce Capital Partners invest at?

Spruce Capital Partners invests at the Series A, Series B, Growth stages.

Where is Spruce Capital Partners located?

Spruce Capital Partners is headquartered in South San Francisco, US.

Spruce Capital Partners

Venture capital

South San Francisco · Series A–Growth · 3 people tracked

Also known as SPRUCE CAPITAL PARTNERS LLC

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Investment thesis

Spruce Capital Partners focuses on the life sciences sector, backing companies that generate positive environmental impact while advancing human health and wellness. Beyond providing capital, the firm takes an active role by creating and advising companies, indicating a hands-on approach that spans company formation, guidance, and investment.

Invests inBiotech Climate Tech Digital Health Healthtech Medical Devices Wellness & FitnessSouth San FranciscoUnited States

Source: firm website, verified Aug 3, 2026.

Stage

Series A–Growth

South San Francisco, California, US

Instruments

Equity

Founded

2013

Private fund assets

$116.6M

VC funds

Tracked investments

Team · 3 people

from the firm's website

Ganesh Kishore· Managing Partner

Ganesh Kishore is a co-founder and Managing Partner at Spruce Capital Partners, with a background in biotechnology research, development, and business. He earned a Ph.D. in biochemistry from the Indian Institute of Science and completed postdoctoral training at the University of Texas at Austin. His earlier career included roles at Monsanto (where he contributed to Roundup Ready technology and Aspartame synthesis and led its Nutrition & Consumer Sector), Chief Technology Officer of Agriculture & Nutrition and later Chief Biotechnology Officer at DuPont, and CEO of the Malaysian Life Science Capital Fund.

k•••@sprucecp.comreveal

Greg Young· Managing Partner

Greg Young is a Managing Partner and co-founder of Spruce Capital Partners, with over eighteen years of experience in biotechnology. He previously served as a Managing Director at Burrill & Company, a financial services firm focused on the life sciences, and earlier worked as a molecular biologist specializing in protein expression at a San Diego biotech startup. His investment focus includes agriculture, renewable energy, chemicals, and biological tools that support sustainability. He holds a BS in Biochemistry and Cell Biology from UC San Diego and an MS in Biotechnology from Northwestern University.

g•••@sprucecp.comreveal

Roger Wyse· Managing Partner

Roger Wyse is co-founder and Managing Partner at Spruce Capital Partners, which he helped launch in 2013. He previously spent time at Burrill & Company from 1998 to 2013, where he served as President and COO of Biogreentech and led its agriculture, food, nutraceuticals, and industrial biotech venture activities. His earlier career included roles as Dean of the College of Agricultural and Life Sciences at the University of Wisconsin-Madison, Dean of Research at Cook College at Rutgers University, and 15 years as a scientist with the USDA-ARS.

r•••@sprucecp.comreveal

What they invest in

from 9 of 12 portfolio companies

Biotech ×6AgTech ×5AI & Machine Learning ×1Climate Tech ×1Digital Health ×1Healthtech ×1Impact & Social Good ×1Wellness & Fitness ×1

HQs:United States×8

Investments · 12 tracked

founders shown can be your intro path

Amfora Inc.SEC filingmedium confidence

BiotechSan Francisco, US

Lindsay Adler(Director)Lloyd Kunimoto(Executive Officer, Director)

Board seatRoger WyseGanesh Kishore· per SEC Form D · $8.3M raise · filed Feb 2021

Infinant Healthinfinanthealth.comin 𝕏SEC filingmedium confidence

Infinant Health develops a B. infantis probiotic pharmaceutical product (INF108, building on EVC001) aimed at preventing necrotizing enterocolitis (NEC) in preterm and very low birth weight infants in NICU care.

BiotechDigital HealthHealthtechWellness & FitnessSacramento, US

Laura Stoppel(Director)Michael Johnson(Executive Officer, Director)Mike Liang(Director)Amanda Birdsey-Benson(Director)Roger Wyse(Director)Patrick Enright(Director)

Board seatRoger Wyse· per SEC Form D · $118.2M raise · filed Jun 2026

Inscriptainscripta.com

BiotechBoulder, US

Michael Graige(Executive Officer)John R. Stuelpnagel(Director)Ron McGrath(Executive Officer)Sri Kosaraju(Executive Officer, Director)Roger Wyse(Director)Dianna L. DeVore(Executive Officer)

Board seatRoger Wyse· per SEC Form D

Agerpointagerpoint.comin 𝕏

Agerpoint provides software tools that use data science and AI to measure and understand crops and trees, generating insights for food and nature systems.

AgTechAI & Machine LearningClimate TechOrlando, US

K. Thomas McPeek(Executive Officer, Director, Promoter)Kevin Lang(CEO & President)Michael Gomes(VP & GM, Intelligent Equipment)Gary Rudolph(VP, Engineering)Mike Batesole(CFO)

Amforaincamforainc.com

Consumer Physicsconsumerphysics.comin 𝕏

Haiyin Shen(Director)Damian Goldring(Executive Officer)Dror Sharon(Executive Officer, Director)William Rosenzweig(Director)

Crop Enhancementcrop-enhancement.com

CropCoat produces a nontoxic coating solution for crops that leaves no residue and does not affect crop quality or taste, designed for growers seeking safer alternatives with no tolerance restrictions for export.

AgTech

Evolve Biosystems in 𝕏

BiotechDavis, US

Daniel Janney(Director)John Campbell(Executive Officer)J. Bruce German(Director)James Campbell(Executive Officer)David Mills(Executive Officer)Catherine Mackey(Director)

GreenLight Biosciencesgreenlightbiosciences.comin

GreenLight Biosciences develops RNA-based solutions for agriculture and pest control, including a Colorado potato beetle bio-insecticide and a Varroa destructor mite-control product for sustainable food production.

AgTechBiotechImpact & Social GoodMedford, US

Andrey Zarur(Executive Officer, Director)Charles L. Cooney(Director)David Furneaux(Director)Marta Ortega-Valle(Executive Officer)William Blake(Executive Officer)Jonathan Fleming(Director)

Mlscfmlscf.com

Pivot Biopivotbio.comin 𝕏

Pivot Bio develops agricultural innovations focused on transforming farming practices through microbiology and genetics.

AgTechBiotechEmeryville, US

Alvin Tamsir(Executive Officer, Director)Karsten Temme(Executive Officer, Director)John Hamer(Director)Matt Ocko(Director)

BoardRoger Wyse(Director)

Proviviprovivi.comin 𝕏

AgTechSanta Monica, US

TULIO RIBEIRO(Director)ALAN BOYCE(Director)James Demetriades(Director)Corey Huck(Executive Officer, Director)Frances Arnold(Director)Peter Meinhold(Executive Officer)

Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.

Frequently asked questions

What stage does Spruce Capital Partners invest at?: Spruce Capital Partners invests at the Series A, Series B, Growth stages.
What sectors does Spruce Capital Partners focus on?: Spruce Capital Partners focuses on Biotech, Climate Tech, Digital Health, Healthtech, Medical Devices, Wellness & Fitness.
Where is Spruce Capital Partners located?: Spruce Capital Partners is headquartered in South San Francisco, US.

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