South San Francisco · Series A–Growth · 3 people tracked
Also known as SPRUCE CAPITAL PARTNERS LLC
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Investment thesis
Spruce Capital Partners focuses on the life sciences sector, backing companies that generate positive environmental impact while advancing human health and wellness. Beyond providing capital, the firm takes an active role by creating and advising companies, indicating a hands-on approach that spans company formation, guidance, and investment.
Source: firm website, verified Sep 29, 2026.
Team · 3 people
from the firm's websiteWhat they invest in
from 11 of 13 portfolio companiesAgTech ×6Biotech ×5AI & Machine Learning ×3Climate Tech ×1Consumer ×1Deep Tech ×1Digital Health ×1EdTech ×1
HQs:United States×8Spain×1
Investments · 13 tracked
founders shown can be your intro pathBy year:2026 · 12023 · 12021 · 12020 · 12016 · 15 dated
Infinant Health develops probiotic products based on B. infantis strains that work with breast milk to support the infant gut microbiome, including its INF108 drug strain aimed at preventing necrotizing enterocolitis (NEC) in premature infants.
BiotechDigital HealthFemTechHealthtechMedical DevicesWellness & FitnessSacramento, US
David J. Kyle(Executive Officer, Director)inJ. Bruce German(Co-founder)David Mills(Founder)inCarlito Lebrilla(Founder)Daniela Barile(Founder)Samara Freeman(Founder & Executive Director, Regulatory Affairs & Intellectual Property)in
Board seatRoger Wyse· per SEC Form D
Co-investorsAcre Venture PartnersBow CapitalHorizons VenturesiSelect FundLongitude CapitalXeraya Capital+1 more
BiotechBoulder, US
Michael Graige(Executive Officer)Ron McGrath(Executive Officer)Sri Kosaraju(Executive Officer, Director)Dianna L. DeVore(Executive Officer)Kevin Ness(Founder)Ryan Gill(Founder)
Board seatRoger Wyse· per SEC Form D
Co-investorsForesite CapitaliGlobe PartnersKorysOak HC/FTOMX VenturesPaladin Capital Group+4 more
Agerpoint provides an AI-powered field intelligence platform that combines smartphone scans, LiDAR, satellite imagery, drones, sensors, and connected equipment data to analyze crops, trees, and field conditions in production agriculture.
AgTechAI & Machine LearningClimate TechOrlando, US
K. Thomas McPeek(Executive Officer, Director, Promoter)inKevin Lang(CEO & President)inMichael Gomes(VP & GM, Intelligent Equipment)inGary Rudolph(VP, Engineering)inMike Batesole(CFO)in
Co-investorsBlackhorn VenturesXeraya CapitalCultivation Capital
Consumer Physics (SCiO) makes a handheld near-infrared spectroscopy scanner paired with a database of molecular signatures to analyze the chemical composition of physical materials.
AgTechAI & Machine LearningDeep TechFoodTechHardwareHerzliya
Damian Goldring(Executive Officer)inDror Sharon(Executive Officer, Director)inHaiyin Shen(Director)William Rosenzweig(Director)
BoardBenny Buller(Director)
Co-investorsXeraya CapitalKhosla VenturesOurCrowd
Crop Enhancement develops CropCoat, a nontoxic crop treatment that leaves no residue on the harvested crop, aimed at agricultural growers.
AgTechNew Materials
Co-investors1955 CapitalBandgap VenturesPhoenix Venture PartnersXeraya Capital
Evolve is a technology education provider offering employability-focused master's degrees delivered 100% online live, plus upskilling and reskilling programs in applied AI, cloud architecture, data engineering, and cybersecurity for companies' technical teams and leadership.
AI & Machine LearningEdTechFuture of WorkMadrid, ES
Davey Richards(Founder)Josef Brocki(Founder)in
Co-investorsGalen PartnersTechstars
Greenlight offers a debit card and mobile app for children that enables parents to set spending limits, automate chores and allowance management, and monitor transactions in real-time.
ConsumerFintechAtlanta, US
Johnson Cook(Founder)inTim Sheehan(Founder)in
BoardAlex Baker(Director)Gardiner Garrard(Director)inChris Olsen(Director)inNeil Underwood(Director)in
Co-investorsAlly VenturesAndreessen HorowitzBond Capital ManagementCanapi VenturesCurql Collective, LLCDrive Capital+20 more
GreenLight Biosciences develops RNA-based solutions for agriculture and pest control, including a Colorado potato beetle bio-insecticide and a Varroa destructor mite-control product for sustainable food production.
AgTechBiotechImpact & Social GoodMedford, US
Andrey Zarur(Executive Officer, Director)inMarta Ortega-Valle(Executive Officer)inWilliam Blake(Executive Officer)in
BoardDavid Furneaux(Director)Jonathan Fleming(Director)James Swartz(Director)
Co-investorsBaird CapitalFall Line CapitalFuture VenturesLewis & Clark VenturesPrelude VenturesS2G Investments+3 more
Pivot Bio develops agricultural innovations focused on transforming farming practices through microbiology and genetics.
AgTechBiotechEmeryville, US
Alvin Tamsir(Founder)inKarsten Temme(Founder)inAlvin Tamsir, Ph.D.(Chief Science Officer & Co-Founder)Karsten Temme, Ph.D.(Chief Innovation Officer and Co-Founder)Chris Abbott(Chief Executive Officer)in
BoardRoger Wyse(Director)in
Co-investorsBreakthrough Energy VenturesCongruent VenturesDCVC (Data Collective)G2 Venture PartnersK3 VenturesK3V Ventures+10 more
AgTechSanta Monica, US
Frances Arnold(Director)inPeter Meinhold(Executive Officer)inPedro Coelho(Executive Officer)inCorey Huck(Executive Officer, Director)in
BoardGANESH KISHORE(Director)inALAN BOYCE(Director)
Co-investorsAliment CapitalKairos Venture Investments, LlcLanx CapitalPontifax AgTechVivo CapitalXeraya Capital+1 more
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
Amfora Inc.AmforaincMlscf
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.
Portfolio news
latest coverage across their companiesAgerpoint · prnewswire.com · Jul 29, 2026
Pivot Bio · pivotbio.com · Jul 1, 2026
Frequently asked questions
- How many investments has Spruce Capital Partners made?
- Spruce Capital Partners has 13 tracked investments, including 1 dated in the last 24 months.
- What stage does Spruce Capital Partners invest at?
- Spruce Capital Partners invests at the Series A, Series B, Growth stages.
- What sectors does Spruce Capital Partners focus on?
- Spruce Capital Partners focuses on Biotech, Climate Tech, Digital Health, Healthtech, Medical Devices, Wellness & Fitness.
- Where is Spruce Capital Partners located?
- Spruce Capital Partners is headquartered in South San Francisco, US.
- Who does Spruce Capital Partners co-invest with?
- Spruce Capital Partners most often shares deals with Xeraya Capital, Prelude Ventures, DCVC (Data Collective), among 38 tracked co-investors.
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