Wireframe Ventures
Actively deployingPre-SeedβSeed
Fund manager profile
Wireframe Ventures is a venture fund manager. SEC filings show 1 venture fund on record, most recently Wireframe Ventures III, L.P. ($100M offering) filed March 2026.
Source: SEC EDGAR Form D filings. Firm website data not yet available.
What they invest in
from 22 of 48 portfolio companiesAI & Machine Learning Γ8Climate Tech Γ6SaaS Γ6Biotech Γ5Cleantech Γ4Data & Infrastructure Γ4Enterprise Software Γ4Hardware Γ4
HQs:United StatesΓ13United KingdomΓ2
Investments Β· 48 tracked
founders shown can be your intro pathNear Space Labs provides high-resolution 7cm geospatial imagery captured from stratospheric altitudes, serving government, utilities, insurance, and environmental monitoring applications with frequent data refresh cycles and wide-scale coverage.
Climate TechData & InfrastructureSpace Tech
Zivian Health builds compliance infrastructure and workforce management software for healthcare providers, nurses practitioners, and physician assistants operating across multiple states or remotely. The platform helps healthcare organizations manage clinical collaboration, regulatory compliance, and team coordination at scale.
Digital HealthHealthtechSaaS
Rafid Fadul(Co-founder, Chief Medical Officer)Griffin Mulcahey(Co-founder, CEO)Jaclyn Miller(Chief Product Officer)Vanessa(Engineering Leader)
Applied Carbon develops technologies to regenerate soil and sequester atmospheric carbon for climate change mitigation and soil health improvement. The company operates at the intersection of agriculture, climate science, and industrial manufacturing.
AgTechCleantechClimate Tech
Jason Aramburu(CEO + Co-Founder)Morgan M. Williams(COO + Co-Founder)
Phytoform Labs develops GM-free genome editing tools and trait engineering technologies for crop improvement, with a focus on potato and tomato varieties. The company works at the intersection of biotechnology and agricultural research to advance sustainable crop breeding.
AgTechAI & Machine LearningBiotechHarpenden, GB
Caladan Bio develops high-throughput benchtop bioreactor hardware and software for laboratory bioprocessing, enabling faster experimentation and lower costs for biotech R&D teams. The company integrates bioreactor equipment with AI-driven process modeling software to support strain optimization and scale-up workflows.
AI & Machine LearningBiotechHardware
Cocoon manufactures LoopCemβ’, a low-carbon supplementary cementitious material made from electric arc furnace slag waste, enabling cement and concrete producers to reduce embodied COβ by up to 27% without cost premium. The company operates within the steel and cement industries to address their combined 14% share of global COβ emissions.
Circular EconomyCleantechClimate TechLondon, GB
Full Harvest builds an agentic intelligence platform that orchestrates transactions and operations across the North American fresh produce supply chain, helping buyers and growers navigate climate volatility, labor shortages, and regulatory complexity. The platform automates procurement, matching, negotiation, and compliance across fragmented supply chain networks in real time.
AgTechAI & Machine LearningLogistics & Supply ChainUnknown, US
Great Sky develops physics-based computational intelligence and AI systems built from foundational research. The company targets applications requiring powerful, adaptive, and resource-efficient AI unconstrained by legacy computing infrastructure.
AI & Machine LearningDeep TechHardwareBoulder, US
Gus Swansen(Senior Hardware Systems Engineer)
Gridware provides real-time monitoring and visibility of electrical grid conditions through sensors deployed on power lines, enabling utilities and line workers to detect and respond to problems faster. The platform serves electric utilities and their field teams to improve grid reliability, reduce outage response time, and prevent wildfire ignition.
Advanced ManufacturingEnergyEnterprise SoftwareHardwareIoTSan Francisco, US
Tim Barat(Founder)inOmar B(Founder)inHall Chen(Co-Founder & CTO)inCo-founded by a lineman turned engineer
LevelTen Energy operates a platform that connects renewable energy developers with customers and market participants, facilitating project visibility and deal-making in the renewable energy sector.
B2B MarketplacesCleantechClimate TechEnergySaaSSeattle, US
Mammoth Bio develops technology to read and write the code of life, operating in the biotechnology sector.
BiotechDeep TechMedical DevicesBrisbane, US
Jennifer Doudna(Founder)Trevor Martin(Co-founder, Chief Executive Officer)Janice Chen(Co-founder, Chief Scientific Officer & President, Research)Lucas Harrington(Co-founder)
OpenInvest builds investment portfolio management software that customizes stock and bond holdings based on individual investor values and ethical preferences, while maintaining performance relative to standard market benchmarks.
FintechSan Francisco, US
Recurrent builds software and data analytics tools to help consumers and dealerships transition to electric vehicles and optimize EV adoption. The company focuses on the automotive sector with a mission to accelerate the decarbonization of transportation.
Climate TechData & InfrastructureMobility & TransportationRetail TechSaaS
ScottBlakeBrian
Regeneron discovers, develops, and manufactures biologics and genetic medicines for treating serious diseases including metabolic disorders, ophthalmology conditions, and rare diseases. The company serves patients globally through clinical trials and commercial pharmaceutical products.
BiotechHealthtechMedical DevicesTarrytown, US
Salient provides AI-powered weather and climate forecasts spanning from 1 day to 1 year using deep learning models trained on ocean and land-surface data. The company serves customers in agriculture, energy, finance, and supply chain sectors seeking improved forecast accuracy for planning and decision-making.
AI & Machine LearningClimate TechData & Infrastructure
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Slack is an AI-powered communication platform that consolidates conversations, applications, and customer interactions in a single workspace for businesses. The platform serves organizations of all sizes across 150+ countries and integrates with 2,500+ apps to automate workflows and enhance workplace productivity.
Enterprise SoftwareFuture of WorkSaaSSan Francisco, US
SuperCircle is a technology and reverse logistics platform that helps retail brands launch trade-in programs and manage excess inventory to reduce textile waste. The company serves fashion and retail brands seeking to implement circular economy practices.
Circular EconomyLogistics & Supply ChainSaaS
Synop provides an all-in-one platform for managing electric vehicle fleets and charging infrastructure, optimizing performance and energy management for commercial fleet operators. The software helps businesses manage EV charging at scale with AI-powered insights, energy storage coordination, and grid integration.
EnergyEnterprise SoftwareSaaS
Tembo builds a platform that serves as an operating layer for software engineering teams, providing secure execution, shared context, and workflow coordination for AI coding agents. The system connects agents to repositories, tools, dependencies, and approval processes.
AI & Machine LearningCloud ComputingDeveloper ToolsEnterprise Software
Astronomer provides Astro, a platform for running Apache Airflow, the open-source data orchestration tool used by enterprises to manage AI, ML, and analytics pipelines at scale.
AI & Machine LearningCloud ComputingData & InfrastructureDeveloper Tools
Board seats Β· per SEC filings Β· 2
what is this? β$6M raise Β· filed Aug 2022 Β· via Paul Straub
$32M raise Β· filed Apr 2021 Β· via Paul Straub
Inferred from directors named on each company's SEC Form D β public regulatory data, not a portfolio list published by the firm.
Frequently asked questions
- What stage does Wireframe Ventures invest at?
- Wireframe Ventures invests at the Pre-Seed, Seed stages.
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