Fundraising Fox
Wireframe Ventures
Venture capitalActively deployingSan Francisco · Pre-Seed–Seed · 3 people tracked
Also known as Wireframe · WIREFRAME MANAGEMENT, LLC
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Investment thesis
Wireframe backs founders tackling some of the world's most important challenges. Drawing on the team's experience as investors and operators, the firm has developed networks and domain expertise across themes it cares about, and works closely with founders from inception through success. As first-check investors, Wireframe positions itself as fully aligned with founders from the outset. The firm also emphasizes building a community where founders can exchange hard-earned lessons with peers and support the next generation of entrepreneurs as they succeed.
Source: firm website, verified Sep 29, 2026.
Team · 3 people
from public directoriesWhat they invest in
from 48 of 56 portfolio companiesAI & Machine Learning ×17Biotech ×16Climate Tech ×13Cleantech ×10Energy ×9Healthtech ×9Deep Tech ×8SaaS ×7
HQs:United States×42United Kingdom×2Israel×1Singapore×1
Who they back
founder profiles across 32 portfolio companiesFounding team size:solo founder×82 founders×143 founders×54+ founders×5
Where their founders studiedfrom 50 founders with education data
Massachusetts Institute of Technology ×5Stanford University ×5Princeton University ×4University of California, Berkeley ×3University of Wisconsin-Madison ×3AngelPad ×2Brown University ×2Duke University ×2
What their founders studiedfrom 52 founders with field-of-study data
Computer Science ×13Engineering ×9Life Sciences ×9Business & Management ×7Economics ×5Mathematics & Statistics ×5Chemistry ×3Humanities ×3
Where their founders worked beforefrom 50 founders with career history
Stanford University ×7Bridgewater Associates ×3Los Alamos National Laboratory ×3Meta ×3Adentro ×2AliveCor ×2Google ×2Harvard Medical School ×2
Accelerator rootsportfolio companies that came through a program
16 founders hold a PhD · 4 hold an MBA (of 52 with degree data)
Investments · 56 tracked
founders shown can be your intro pathBy year:2026 · 42025 · 12024 · 42022 · 52021 · 22020 · 12019 · 12018 · 22017 · 12015 · 122 dated
Fuel Tech provides emissions control systems targeting NOx, SO3, ABS, PM2.5, and CO2, with over 2,100 systems installed across 27 countries, and also offers DGI Dissolved Gas Infusion technology for fresh water treatment.
CleantechClimate TechEnergyWarrenville, US
Vincent Arnone(Executive Officer, Director)inEllen Albrecht(Executive Officer)inDennis Zeitler(Director)Thomas Shaw, Jr.(Director)Sharon Jones(Director)Douglas Bailey(Director)
Co-investorsInspired CapitalSpero Ventures
Palantir builds data integration and analysis platforms — Gotham for defence and government, Foundry for commercial operations — and deploys forward engineers inside customer organisations.
Palo Alto, US
Peter Thiel(Co-founder and Chairman)inStephen Cohen(Co-founder and President)Nathan Gettings(Co-founder)Joe Lonsdale(Co-founder)inAlexander C. Karp(Co-founder and CEO)
BoardColin Anderson(Executive Officer)in
Co-investors137 Ventures8VCA*AiSprouts VCAkkadian VenturesAllied Venture Partners+67 more
Bedrock Energy develops drilling technology and data algorithms for designing and installing geothermal borehole fields used for building heating and cooling.
CleantechClimate TechEnergyLos Angeles, US
Silviu Livescu(Executive Officer)inJoselyn Lai(Executive Officer, Director)inJoel Wishkovsky(Executive Officer, Director)
Board seatPaul Straub· per SEC Form D
Co-investorsCantos VenturesDivergent CapitalEnergy Impact PartnersFirst Star VenturesThird DerivativeTitanium Ventures+5 more
San Francisco, US
Muffadal Ghadiali(Executive Officer, Director, Promoter)Naeem Zafar(Director)
BoardJulie Lein(Director)in
Board seatPaul Straub· per SEC Form D
Co-investorsAcario InnovationBlackhorn VenturesUrban InnovationLemnos VC
Salient produces AI-powered subseasonal-to-seasonal weather and climate forecasts spanning one day to one year, using deep neural networks trained on ocean, land-surface, and climate data.
AI & Machine LearningClimate TechDeep TechFalmouth, US
Matthew Stein(Executive Officer, Director)Raymond Schmitt(Executive Officer, Director)inRay Schmitt(Co-founder)inEric Schmitt(Co-founder)inStephen Schmitt(Co-founder)in
Board seatPaul Straub· per SEC Form D
Co-investorsBlindspot Ventures Management CoEndeavor8First Star VenturesMunich Re Ventures
SPAN develops smart electrical panels that provide real-time home energy monitoring and control, enabling homeowners to track and optimize energy consumption at the room and appliance level to reduce energy bills.
CleantechHardwareIoTSan Francisco, US
Arch Rao(Founder & CEO)inArchan Rao(Executive Officer, Director)Douglas Booms(Executive Officer)inRyan Harris(Executive Officer)in
BoardDipender Saluja(Director)Greg Wasserman(Director)
Board seatPaul Straub· per SEC Form D
Co-investorsAngeleno GroupArcTern VenturesClimate CapitalCollaborative FundCongruent VenturesDesigner Fund+21 more
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Applied Carbon develops technologies to regenerate soil and sequester atmospheric carbon for climate change mitigation and soil health improvement.
AgTechCleantechClimate Tech
Jason Aramburu(CEO + Co-Founder)inMorgan M. Williams(COO + Co-Founder)in
Co-investorsAutodesk FoundationCongruent VenturesS2G InvestmentsTO VCZag CapitalOverture Climate+1 more
Argon provides software supply chain security that connects to existing CI/CD pipelines via an agentless implementation to map development environments, assets, code, and user activities, and uses code-tampering detection to prevent supply chain attacks.
Cloud ComputingCybersecurityDeveloper ToolsTel Aviv, IL
Eilon Elhadad(CEO and Co-Founder, Argon)in
Co-investorsHyperwise VenturesCrosslink CapitalY Combinator
Argon AI provides an AI-native workspace designed for life sciences, clinical, and commercial teams that automates research workflows, generates insights from medical data, and accelerates drug development processes.
AI & Machine LearningBiotechEnterprise SoftwareHealthtechNew York City, US
Samy Danesh(Founder)inCyrus Jia(Founder)inSamyar Danesh Bahreini(Executive Officer, Director, Promoter)
Co-investorsCrosslink CapitalY CombinatorEight CapitalKleiner PerkinsOrange CollectiveOurCrowd+3 more
Monte Nido provides evidence-based residential and virtual treatment programs for eating disorders across all diagnoses, with specialized care for adolescents and adults.
Digital HealthHealthtechMental HealthWellness & Fitness
Co-investorsAcumen AmericaAlumni VenturesBluestein VenturesFTW VenturesVery Serious VenturesBBG Ventures+1 more
GeneSight offers pharmacogenomic testing that analyzes how a patient's genes affect their response to psychiatric medications, helping clinicians optimize treatment selection and dosing for conditions like depression, anxiety, and ADHD.
BiotechDigital HealthHealthtechMedical DevicesMental Health
Co-investorsAllos VenturesCincyTechCross Creek Advisors
Astronomer provides Astro, a platform for running Apache Airflow, the open-source data orchestration tool used by enterprises to manage AI, ML, and analytics pipelines at scale.
AI & Machine LearningCloud ComputingData & InfrastructureDeveloper ToolsCincinnati, US
Ry Walker(Founder)inViraj Parekh(Founder)inJoe Otto(Founder)inGreg NeiheiselTim Brunk(Executive Officer, Director)inRyan Walker(Executive Officer, Director)
Co-investors500 GlobalAngelPadBain Capital VenturesBosch VenturesCincyTechConnetic Ventures+12 more
Caladan provides financial services or investment management, with a team drawn from finance, real estate, and creative backgrounds.
Crypto & Web3FintechSector AgnosticSingapore, SG
John GuNigel YoungEva WenginRemi ColinmaireinStephany Zooin
Co-investorsAlphaLab CapitalCollaborative FundLerer HippeauTwelve Below
Caladan Bio develops high-throughput benchtop bioreactor hardware and software for laboratory bioprocessing, enabling faster experimentation and lower costs for biotech R&D teams.
AI & Machine LearningBiotechHardwareNew York, US
Michael Kobida(Founder)inRob Jauquet(Founder)in
Co-investorsCollaborative FundLerer HippeauRitual CapitalTwelve BelowFactorial Capital
CanopyClimate helps companies, non-profits, and organizations measure and reduce their collective employee emissions through team-based climate action tracking and reporting.
CleantechClimate TechEnergyEnterprise SoftwareFintechSaaS
Co-investorsBuoyant Ventures Management, Llc
Cocoon develops low-carbon construction materials, including LoopCem, a supplementary cementitious material (SCM) made by valorizing electric arc furnace (EAF) steel slag to reduce concrete emissions.
Circular EconomyCleantechClimate TechNew MaterialsLondon, GB
Eliot Brooks(CEO)inWilliam Knapp(Founder)inFreddie Scott(CTO)in
Co-investorsBrick Mortar VenturesGigascale CapitalSOSVThe Venture CollectiveFirst Round CapitalIndex Ventures+4 more
DNAnexus operates a cloud platform for managing, analyzing, and collaborating on multiomic and clinical data, supporting bioinformatics workflows, AI/ML analytics, and cohort analysis.
AI & Machine LearningBiotechCloud ComputingData & InfrastructureMountain View, US
Andreas Sundquist(Executive Officer, Director)inRichard Daly(Executive Officer, Director)inGeorge Asimenos, PhD(Chief Product Officer)in
BoardMichael Goldberg(Director)Geoff Duyk(Director)Krishna Yeshwant(Director)in
Co-investorsClaremont Creek VenturesForesite CapitalGV (Google Ventures)K9 VenturesSaints CapitalUncork Capital
Endpoint Health develops precision medicine tools and targeted therapies for patients with critical illnesses like sepsis and ARDS, leveraging big data and AI to personalize treatment.
AI & Machine LearningBiotechDigital HealthHealthtechMedical DevicesSan Jose, US
Jason Springs(Co-Founder, CEO)Diego Rey(Co-Founder, CSO)Leonardo Teixeira(Co-Founder, COO)Jeff Osborn(Co-Founder, CTO)
Co-investorsHumboldt
Endpoint Health develops immunology-focused therapeutics paired with diagnostic tests designed to match individual patients with treatments suited to their biology for critical and chronic illnesses.
BiotechHealthtechSan Francisco, US
Diego Rey(Founder/CSO)inJeff Osborn(Founder)inJason Springs(Founder)inLeonardo Teixeira(Founder)in
Co-investorsAlix VenturesGlobal Health Investment CorporationKnockout CapitalY CombinatorAME Cloud VenturesBoom Capital Ventures+5 more
Enveda operates a drug-discovery platform that analyzes natural samples—primarily plant-derived molecules—using mass spectrometry, AI foundation models, and automated high-throughput labs to identify their chemical structures and therapeutic properties.
AI & Machine LearningBiotechDeep TechBoulder, US
Viswa Colluru, PhD(Founder)inViswa Colluru(Executive Officer, Director)inDaniel Wee(Executive Officer)
BoardRohit Sharma(Director)Zavain Dar(Director)inBruce Beutel(Director)
Co-investorsAir Street CapitalBoulder VenturesCatalio Capital Management, LPCox EnterprisesFPVHummingbird Ventures+18 more
AI copilot for private credit and asset-backed finance
Co-investorsCongruent Venturesfresh.fundPenny Jar Capital VentureA16Z SpeedrunKDXLeap Forward Ventures+4 more
Full Harvest builds an agentic intelligence platform that orchestrates transactions and operations across the North American fresh produce supply chain, helping buyers and growers navigate climate volatility, labor shortages, and regulatory complexity.
AgTechAI & Machine LearningLogistics & Supply Chain
Co-investorsAstiaDoon CapitalGolden Seedsmark vcPortfoliaRabo Corporate Venturing+5 more
Geneticure offers a patented genetic test that uses a cheek-swab DNA sample, analyzing 17 genotypes across 11 genes to recommend personalized hypertension (blood pressure) treatment plans.
BiotechDigital HealthHealthtechMedical DevicesEden Prairie, US
Scott Snyder(Chief Executive Officer)inEric Snyder(Chief Operating Officer)inRyan Sprissler(Chief Scientific Officer)inTom Olson(Chief Clinical Officer)
Co-investorsSoutheast Minnesota Capital Fund
Great Sky develops physics-based computational intelligence and AI systems built from foundational research.
AI & Machine LearningDeep TechHardwareBoulder, US
Jeffrey Shainline(Founder & CEO)inJeffrey Chiles(Co-Founder & CTO)inBryce Primavera(Co-Founder & VP of Architecture)inSaeed Khan(Co-Founder & VP of Fabrication)inMark Wade(Director)in
BoardTom Biegala(Director)in
Co-investorsBison VenturesMatchstick VenturesMythos Ventures Management, LlcOlive Tree CapitalRange VCService Provider Capital+3 more
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Gridware provides real-time monitoring and visibility of electrical grid conditions through sensors deployed on power lines, enabling utilities and line workers to detect and respond to problems faster.
Advanced ManufacturingClimate TechEnergyEnterprise SoftwareHardwareIoTSan Francisco, US
Tim Barat(Founder)inOmar B(Founder)inHall Chen(Co-Founder & CTO)in
Co-investorsAiSprouts VCAnorak VenturesBragiel BrothersConvective CapitalFifty YearsHAWKTAIL+15 more
LevelTen Energy operates a platform that connects renewable energy developers with customers and market participants, facilitating project visibility and deal-making in the renewable energy sector.
B2B MarketplacesCleantechClimate TechEnergySaaSSeattle, US
Bryce Smith(Executive Officer, Director)inSmith Bryce(Executive Officer, Director)inWilliam Thomas(Executive Officer)
BoardDavid Cohen(Director)inKarly Wentz(Director)inGreg Lyons(Director)
Co-investorsAster CapitalB Capital GroupB4 CapitalConstellation Technology VenturesE8 AngelsPrelude Ventures+7 more
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Mammoth Bio develops technology to read and write the code of life, operating in the biotechnology sector.
BiotechDeep TechMedical DevicesBrisbane, US
Jennifer Doudna(Founder)inTrevor Martin(Co-founder, Chief Executive Officer)inJanice Chen(Co-founder, Chief Scientific Officer & President, Research)inLucas Harrington(Co-founder)inAshley Tehranchi(Executive Officer, Director)in
BoardUrshit Parikh(Director)
Co-investors8VCBerkeley FrontierCALIFORNIA INNOVATIONDecheng CapitalForesite CapitalMayfield Fund+10 more
MycoWorks produces Reishi, a premium biomaterial made from Fine Mycelium, used as a sustainable leather alternative in furniture, design, and automotive products.
BiotechCircular EconomyNew MaterialsEmeryville, US
Philip Ross(Director)inMichael Lindheim(Executive Officer)Matthew Scullin(Executive Officer, Director)in
BoardKiersten Stead(Director)inThomas Grotkjaer(Director)
Co-investorsATEL VenturesDCVC (Data Collective)Hemisphere Ventures LLCValor Equity Partners8VCAgFunder+7 more
Tillamook, US
Kristen S. Lachenmeier(Executive Officer)Dennis Knapp(Director)Timothy Lachenmeier(Executive Officer, Director)Kevin L. Tucker(Executive Officer, Director)Katherine Cowan(Director)
Co-investorsBold Capital PartnersCrosslink CapitalLeadout CapitalToyota Ventures
Near Space Labs provides high-resolution 7cm geospatial imagery captured from stratospheric altitudes, serving government, utilities, insurance, and environmental monitoring applications with frequent data refresh cycles and wide-scale coverage.
Climate TechData & InfrastructureSpace TechBrooklyn, US
Rema Matevosyan(Founder & CEO)inHripsime Matevosyan(Executive Officer, Director)Albert Caubet Domingo(Director)
Co-investorsAt One VenturesBlackhorn VenturesBold Capital PartnersCrosslink CapitalDraper AssociatesGreen Egg Ventures+7 more
OpenInvest builds investment portfolio management software that customizes stock and bond holdings based on individual investor values and ethical preferences, while maintaining performance relative to standard market benchmarks.
FintechSan Francisco, US
Conor Murray(Founder/CEO)inPhillip Wei(Founder/CTO)inPhilip Wei(Executive Officer, Director)
Co-investorsAbstract VenturesAndreessen HorowitzSystemiq CapitalY CombinatorAlumni VenturesFlat World Partners+4 more
Passkey operates Locksmith, a computational platform that uses human genetics, biology, and pharmacology to identify synergistic drug combinations from approved and late-stage drugs, allowing existing assets to be repurposed for new indications.
AI & Machine LearningBiotechDeep Tech
Co-investorsBison VenturesBreakout Ventures
Pasture Bio develops a vaccine designed to disrupt methane-producing microbes in cattle's rumen, reducing enteric fermentation emissions while improving productivity and animal health.
AgTechBiotechClimate TechSan Francisco, US
Co-investorsCavallo VenturesGigascale Capital
Phytoform Labs develops GM-free genome editing tools and trait engineering technologies for crop improvement, with a focus on potato and tomato varieties.
AgTechAI & Machine LearningBiotechHarpenden, GB
William Pelton(Executive Officer, Director)inNicholas Kral(Director)Dhiraj Singh(Director)
Co-investorsBackedEniac VenturesFine Structures VenturesFTW VenturesManta Ray VenturesRefactor Capital+1 more
Recurrent builds software and data analytics tools to help consumers and dealerships transition to electric vehicles and optimize EV adoption.
Climate TechData & InfrastructureMobility & TransportationRetail TechSaaS
Scott Case(Founder)in
Co-investorsArcTern VenturesAscend Venture CapitalAutomotive Ventures MobilityE8 AngelsEnerTech CapitalGoodyear Ventures+6 more
Regeneron is a biotechnology company that develops medicines ranging from biologics to genetic medicines to treat serious diseases across areas such as metabolic disease, ophthalmology, and rare disease.
BiotechHealthtechTarrytown, US
Co-investorsRidgeback CapitalSanderling VenturesvenBio Partners
Reverie Labs develops cancer treatments designed to cross the blood-brain barrier and treat tumors in the central nervous system.
AI & Machine LearningBiotechHealthtechBoston, US
Ankit Gupta(Founder/CTO)inConnor Duffy(Founder)inJonah Kallenbach(Founder)in
Co-investorsDorm RoomLifeforce CapitalRuvento Ventures Pte Ltd.UNCOMMON DENOMINATORWormhole CapitalY Combinator+15 more
New York, US
Kurt Breitenkamp(Executive Officer, Director)Orion Cohen(Executive Officer, Director)Ian Samuels(Director)Sarah Istel(Director)
Co-investorsSocial Starts
Video editing and collaboration platform.
Co-investorsRembrandt Venture PartnersScribble VenturesTransmedia CapitalFreestyle CapitalGreylock Partners
Siren Optics builds material analysis systems that use cold atmospheric plasma and AI to perform real-time, non-destructive inspection of materials such as wafers, films, coatings, and battery components.
Advanced ManufacturingAI & Machine LearningDeep TechOakland, US
Jared O'Leary(Executive Officer, Director, Promoter)inALI MESBAH(Director)in
BoardMatthew Blaine(Director)TOM CHI(Director)MATTHEW BLAIN(Director)PHILIP HARPER(Director)
Co-investorsInMotion VenturesUNION Labs VenturesAt One VenturesVoyager Partners
Slack is an AI-powered communication platform that consolidates conversations, applications, and customer interactions in a single workspace for businesses.
Enterprise SoftwareFuture of WorkSaaSSan Francisco, US
Cal Henderson(Co-founder & CTO)inStewart Butterfield(Co-founder & CEO)in
Co-investors1991 VenturesAccelACME CapitalAcrew CapitalAglae VenturesAndreessen Horowitz+46 more
Sora Fuel produces sustainable aviation fuel (SAF) and diesel using a proprietary closed-loop direct air capture and conversion process that draws carbon from air rather than biomass or industrial feedstocks.
CleantechClimate TechEnergyCambridge, US
Curtis BerlinguetteinGareth Ross(Executive Officer, Director)inCurtis Belinguete(Director)
BoardPatrick Sarver(Director)inMarc Tarpenning(Director)inMichael Kearney(Director)in
Co-investorsInnovation UBCInspired CapitalLeitmotifSpero VenturesThe Engine Ventures
Sora Schools provides an engaging, personalized learning experience built by educators, designers, and engineers.
EdTechAtlanta, US
Indra Sofian(Director)inWesley Samples(Executive Officer, Director)Garrett Smiley(Founder)in
BoardTed Dintersmith(Director)Rebecca Kaden(Director)inMichael Lynton(Director)
Co-investorsContraryHoneystone VenturesInspired CapitalUnion Square Ventures (USV)CRV (Charles River Ventures)General Catalyst+6 more
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SuperCircle is a technology and reverse logistics platform that helps retail brands launch trade-in programs and manage excess inventory to reduce textile waste.
Circular EconomyLogistics & Supply ChainSaaS
Chloe Marie Songer(Founder)inStuart Ahlum(Founder)in
Co-investorsFab Co-Creation Studio VenturesFoundryRadicle ImpactRareBreed VenturesRenewal FundsStarting Line+4 more
Synop provides an all-in-one software platform for managing commercial electric vehicle fleets, charging stations, and distributed energy resources such as battery storage.
EnergyMobility & TransportationSaaSCarmel, US
Andrew Blejde(Executive Officer, Director)inGagan DhilloninGagandeep Dhillon(Executive Officer, Director)
Co-investorsBetter Ventures Central LlcCongruent VenturesObvious Ventures
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Tembo builds a platform that serves as an operating layer for software engineering teams, providing secure execution, shared context, and workflow coordination for AI coding agents.
AI & Machine LearningCloud ComputingDeveloper ToolsEnterprise Software
Co-investorsGreatPoint VenturesAlumni VenturesAscensionCincyTechCintrifuse CapitalGrand Ventures+5 more
Terraline offers a software-defined vehicle (SDV) platform that unifies vehicle control and telemetry, providing over-the-air updates, digital dashboards, and autonomy-ready APIs for intelligent machines and vehicles.
HardwareIoTMobility & TransportationMountain View, US
Co-investorsiNetworksManiv MobilityTrucks VC
Think Bioscience develops new medicines for diseases with limited treatment options through synthetic biology and computational chemistry.
BiotechDeep Tech
Co-investorsAV8 VenturesBuff Gold VenturesColorado BioScience AssociationCU Healthcare Innovation FundAxial VCInnovation Endeavors
Trove operates a platform for brand resale and recommerce, enabling iconic brands to sell returned and excess inventory through secondary markets.
AI & Machine LearningB2B MarketplacesCircular EconomyRetail TechBrisbane, US
ANDREW RUBEN(Director, Promoter)John Connolly(Founder)inGAYLE TAIT(Executive Officer, Director)in
BoardGABRIEL KRA(Director)inBROOK PORTER(Director)inSHELLEY BRANSTEN(Director)
Co-investorsArcTern VenturesClaremont Creek VenturesCommerce VenturesDBL PartnersG2 Venture PartnersGlobal Brain+5 more
Tyba builds technology and modeling tools to help companies develop and operate energy storage projects more profitably.
AI & Machine LearningCleantechClimate TechEnergySan Francisco, US
Michael Baker(Co-founder & CEO)inTom Thunell(Co-Founder & COO)inTyler(Co-Founder & CTO)
Co-investorsEnergize CapitalLorimer VenturesPear VCVirta Ventures
Xcimer Energy develops laser-driven inertial fusion technology, aiming to turn decades of fusion research into commercial fusion power plants that provide large-scale electricity while supporting air defense and national security applications.
CleantechDeep TechEnergyDenver, US
Conner Galloway(Executive Officer, Director)inAlexander Valys(President, Founder)inBrent Gill(Chief Operating Officer)inGary Sobolevskiy(General Counsel)in
Co-investorsBreakthrough Energy VenturesGigascale CapitalLeitmotifLowercarbon CapitalPrelude VenturesStarlight Ventures
Xtelligent develops next-generation traffic signal control technology using control algorithms, real-time data streams, and machine learning to enable adaptive, multimodal, and cooperative management of signalized intersections for cities.
AI & Machine LearningGovTechMobility & Transportation
Co-investorsCongruent VenturesThird Sphere
Zivian Health builds compliance infrastructure and workforce management software for healthcare providers, nurses practitioners, and physician assistants operating across multiple states or remotely.
Digital HealthHealthtechSaaS
Rafid Fadul(Co-founder, Chief Medical Officer)inGriffin Mulcahey(Co-founder, CEO)inJaclyn Miller(Chief Product Officer)inVanessa(Engineering Leader)
Co-investorsRally Ventures Management, LlcCrosslink CapitalNextView VenturesBlumberg CapitalGradient Ventures
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
CocoonCarbon, Inc.Mammoth BioSolo AVT
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.
Exits · 4
2 IPOs · 2 acquisitions · showing 2Fuel TechNASDAQ: FTEKPalantir Technologies Inc.NASDAQ: PLTR
Portfolio news
latest coverage across their companies
Xcimer · techcrunch.com · Aug 15, 2026
Enveda Biosciences · enveda.com · Jul 8, 2026
Fuel Tech · ftek.com · May 1, 2026
Sora Fuel · finsmes.com · Apr 8, 2026
Cocoon · finsmes.com · Mar 18, 2026
Great Sky · finsmes.com · Mar 16, 2026
Ezra · gamesbeat.com · Mar 12, 2026
SPAN · bizjournals.com · Jan 28, 2026
Frequently asked questions
- How many investments has Wireframe Ventures made?
- Wireframe Ventures has 56 tracked investments, 4 of which have exited, including 5 dated in the last 24 months.
- What stage does Wireframe Ventures invest at?
- Wireframe Ventures invests at the Pre-Seed, Seed stages.
- What is Wireframe Ventures's typical check size?
- Wireframe Ventures typically writes checks of $500K – $2M.
- What sectors does Wireframe Ventures focus on?
- Wireframe Ventures focuses on Biotech, Cleantech, Climate Tech, Energy, Healthtech, Impact & Social Good, Sector Agnostic.
- Where is Wireframe Ventures located?
- Wireframe Ventures is headquartered in San Francisco, US.
- Does Wireframe Ventures lead rounds?
- Yes, Wireframe Ventures leads investment rounds.
- Who does Wireframe Ventures co-invest with?
- Wireframe Ventures most often shares deals with Congruent Ventures, Prelude Ventures, ArcTern Ventures, among 237 tracked co-investors.
Media · Podcasts & interviews
featuring the teamPaul Straub | Co-Founder & Managing Director, Wireframe Ventures
ZNRG - The ZENERGY Podcast · Paul Straub
Ventures #5 w/ Harsh Patel - Managing Partner & Co-Founder @ Wireframe Ventures | BIOS
BIOS · Harsh Patel
Ep.#47: Partnering with founders for human and planetary health: Paul Straub from Wireframe Ventures
StartupBasecamp org · Paul Straub
EDGE Chats: Paul Straub, Co-Founder and Managing Partner, Wireframe Ventures
Duke University - The Fuqua School of Business · Paul Straub
Why Apply to SkyDeck? | Why Apply to SkyDeck? Harsh Patel of Wireframe Ventures shares why early-stage VCs work with SkyDeck to identify Cal's top tech talent. | By Berkeley SkyDeckFacebook
Harsh Patel · facebook.com
Co-investors · 11
Gigascale Capital is an early-stage investment firm backing founders building physical systems and infrastructure across energy, factories, supply chains, and infrastructure for climate impact.
GV (Google Ventures) is a venture capital firm that has invested in AI and machine learning since its early days, backing more than 100 AI companies across infrastructure, life sciences, and applications.
SOSV is a deep tech venture capital firm that makes first-check pre-seed investments and follow-on rounds in startups focused on human and planetary health, providing lab space and hands-on support at its US locations.
G2 Venture Partners is a venture capital firm that invests in technology companies at their inflection points to help transform traditional industries toward sustainability.
Urban Innovation Fund is a seed-stage venture firm that backs startups transforming large, regulated industries such as energy, transportation, and fintech, offering capital, hands-on support, and regulatory insight.
Allos Ventures is a Midwest-focused venture capital firm that invests in early-stage B2B software and tech-enabled services companies, drawing on decades of experience to take a hands-on approach.
muru-D is Telstra's innovation hub focused on incubating ideas, products, and technologies, prototyping solutions and accelerating a portfolio of start-ups across Australia, Asia, and the USA.
Piva Capital is a venture capital firm that invests in companies aiming to shape the future for humanity.
1517 is a venture capital fund and community backing college dropouts, uncredentialed founders, and deep tech scientists at the earliest stages, from R&D/idea through seed. It was founded by the cofounders of the Thiel Fellowship and also provides grants and a global community of hackers, makers, and scientists.
Active Impact Investments is a climate tech seed fund based in Canada, backing early-stage companies that advance planetary sustainability by innovating across production and consumption industries.
VentureUs is an angel investment group focused on seed and early-stage companies in the Pacific Northwest, using a member-advised, participatory process to source, evaluate, and fund startups.
Firms observed investing alongside Wireframe Ventures, from public investor directories. Shared companies are the overlap with Wireframe Ventures's recorded portfolio.
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