Columbus Venture Partners

Arthex Biotech develops antisense RNA compounds to treat diseases with unmet medical needs.

AI & Machine LearningBiotechMedical Devices

Beatriz Llamusí(Chief Scientific Officer & Co-Founder)in

PartnerJose Mesa· solo GP

Co-investorsBpifranceHadean VenturesSound BioventuresAdBio partnersInvivo Capital Partners

Quatre Lab is a Contract Research Organization specializing in quality control testing and validation of Advanced Therapy Medicinal Products (ATMPs) for biotech and pharmaceutical companies.

BiotechDeep TechHealthtechMedical DevicesSpain, ES

Patricia Muñoz(Managing Director)Columbus Venture Partners

PartnerJose Mesa· solo GP

Tyris Therapeutics develops non-viral gene therapies using a proprietary DNA format (oDNA™) to treat rare and prevalent genetic diseases.

BiotechDeep TechHealthtechMedical DevicesValencia, ES

PartnerJose Mesa· solo GP

Vivet Therapeutics is a clinical-stage biotechnology company developing recombinant adeno-associated virus (rAAV) gene therapies for rare, inherited metabolic diseases, including Wilson's Disease and cerebrotendinous xanthomatosis.

BiotechHealthtechParis, FR

PartnerJose Mesa· solo GP

Co-investorsHealthCapKurma PartnersNovartis Venture FundRoche Venture FundYsios CapitalEurazeo+1 more

Accipiter Biosciences uses computational protein design to develop de novo, single-agent protein therapies that engage multiple cell-surface receptors at once, functioning as agonists.

AI & Machine LearningBiotechDeep TechSeattle, US

Matthew Bick(Executive Officer, Director, Promoter)inJavier Castellanos(Executive Officer, Director, Promoter)Hector De Jesus Rincon Arano(Executive Officer, Promoter)Heather Redman(Director)Randall Schatzman(Director)William Canestaro(Executive Officer)

PartnerJose Mesa· solo GP

Co-investorsArgonautic VenturesPack VenturesWRF Capital

Advanthera integrates regulatory guidance and clinical supply chain services to accelerate the development and manufacture of advanced therapies and innovative medicines.

AI & Machine LearningBiotechMedical Devices

Columbus Venture Partners

PartnerJose Mesa· solo GP

Aleta Biotherapeutics develops multi-antigen CAR T Engager (CTE) biologics designed to improve the effectiveness of CAR T cell cancer therapies by increasing target antigen density and preventing cancer escape.

BiotechDeep TechHealthtech

PartnerJose Mesa· solo GP

Algenex develops proprietary baculovirus expression technologies and manufacturing processes for producing recombinant proteins used in pharmaceuticals and diagnostics.

Advanced ManufacturingBiotechDeep TechMedical Devices

PartnerJose Mesa· solo GP

Alto Pharmacy is a full-service pharmacy that offers patients medication delivery, cost transparency, and pharmacist access.

ConsumerDigital HealthHealthtechSan Francisco, US

James Karraker(Executive Officer, Director)Mattieu Gamache-Asselin(Founder & CEO)inNichola Eliovits(Director)Nathaniel Kan(Director)Robert Spinner(Director)

BoardNeil Shah(Director)in

PartnerJose Mesa· solo GP

Co-investorsAvego BioScience CapitalBantam GroupCalm VenturesCSC UpshotEvolution VC PartnersFlucas Ventures+8 more

Artax Biopharma is a Phase 2 clinical-stage biotechnology company developing first-in-class oral small-molecule Nck modulators that target T cell receptor Signal 1 activation to treat autoimmune diseases without causing immunosuppression.

BiotechHealthtechCambridge, US

Damia Tormo(President, CEO, Treasurer and Founder)inJoe Suarez(Executive Officer)Maria Nichol(Executive Officer)inRobert W. Armstrong, Ph.D.(Executive Officer, Director)Rob Armstrong(CEO)in

BoardAndre Hoekema(Director)

PartnerJose Mesa· solo GP

Co-investorsSound BioventuresAdvent Life Sciences

AskBio is a gene therapy company developing adeno-associated virus (AAV)-based genetic medicines for rare and other diseases, with clinical programs such as AB-1009 for late-onset Pompe disease.

BiotechDeep TechHealthtechDurham, US

PartnerJose Mesa· solo GP

Co-investorsTPGVida Ventures

Cocoon Bioscience operates CrisBio, a recombinant protein expression platform that uses insects in a chrysalis (cocoon) state instead of traditional bioreactors to produce enzymes and complex proteins.

BiotechDeep TechNew Materials

PartnerJose Mesa· solo GP

Curapath is a European Contract Development and Manufacturing Organization (CDMO) specializing in polymer- and lipid-based non-viral drug delivery systems for biotech and pharmaceutical companies.

Advanced ManufacturingBiotechDeep TechHealthtechMedical Devices

Philippe(Chief Executive Officer)Vicent(Chief Technology Officer)

PartnerJose Mesa· solo GP

Curve Therapeutics uses its mammalian cell-based Microcycle discovery platform to develop cyclic peptide and small molecule drugs against intracellular targets.

AI & Machine LearningBiotech

PartnerJose Mesa· solo GP

Co-investorsEpidarex CapitalPfizer Venture Investments

Deepull develops a multiplex PCR diagnostic system to rapidly identify sepsis-causing pathogens and antibiotic resistance markers directly from blood samples in approximately one hour, targeting hospitals and clinical laboratories.

Medical Devices

Co-investorsAsabys Partners

A digital agency offering design and development services—including 3D space configuration, digitizing physical samples into online catalogs, and ticket-sales platforms—for brands across multiple sectors.

Marketing TechSaaS

Highlight Therapeutics is a biotech company developing therapeutic treatments.

BiotechHealthtech

Marisol Quintero(Chief Operating Officer (former CEO 2013-2025))in

PartnerJose Mesa· solo GP

Co-investorsDroia Ventures

PartnerJose Mesa· solo GP

Co-investorsAdBio partnersInvivo Capital Partners

Jurata develops thermostable film-based formulations that allow vaccines and biologics to be stored and shipped without refrigeration and delivered without needles, including an intranasal film.

BiotechDeep TechHealthtechLogistics & Supply Chain

PartnerJose Mesa· solo GP

Lark develops an AI-powered health coaching platform that delivers personalized support for chronic disease prevention and management through 24/7 text-based conversations and integration with smart health devices.

AI & Machine LearningDigital HealthHealthtech

Julia Hu(Founder)in

PartnerJose Mesa· solo GP

Co-investorsAlpha Intelligence CapitalAsset Management CompanyCrunchFundIPD CapitalJoyance PartnersKing River Capital+5 more

Minoryx is a registration-stage biotech company developing novel therapies for severe, orphan genetic diseases of the central nervous system, with a lead compound (leriglitazone) in clinical trials for conditions including cerebral adrenoleukodystrophy, Friedreich's Ataxia, and Rett syndrome.

BiotechDeep TechHealthtechMedical DevicesMataró, ES

Marc Martinell(Co-Founder & Chief Executive Officer)in

PartnerJose Mesa· solo GP

Co-investorsChiesi VenturesCriteria Bio VenturesFund+Invivo Capital PartnersKurma PartnersRoche Venture Fund+1 more

PartnerJose Mesa· solo GP

Co-investorsAdvent Life SciencesFountain Healthcare PartnersOrbiMed

Ona provides cloud-based agent infrastructure that runs developer tasks in isolated environments while laptops are closed, automating workflow execution through events, schedules, and pull requests.

AI & Machine LearningCloud ComputingDeveloper Tools

Co-investorsBright Pixel CapitalCrane Venture PartnersPebblebedPreston-Werner VenturesAlta Life SciencesKorys+1 more

Ona Therapeutics develops therapeutic antibodies targeting lipid metabolism to treat advanced and metastatic cancers, including liposarcoma.

BiotechHealthtechMedical Devices

Co-investorsFund+KorysMérieux Equity PartnersYsios CapitalAlta Life SciencesAsabys Partners+2 more

Quibim develops cloud-based AI software platforms for medical imaging analysis that extract radiomics features and generate predictive models for healthcare providers and biopharma companies.

AI & Machine LearningHealthtechMedical Devices

PartnerJose Mesa· solo GP

Co-investorsAdara VenturesAmadeus Capital PartnersAPEX VenturesLifeX VenturesAsabys PartnersGoHub Ventures

PartnerJose Mesa· solo GP

PartnerJose Mesa· solo GP

Artis BioSolutions is an integrated platform for genetic medicine that produces enzymatically synthesized synthetic DNA and develops it into clinical-grade advanced therapies with in-house GMP manufacturing.

Advanced ManufacturingBiotechMedical DevicesWatertown, US

PartnerJose Mesa· solo GP

Co-investorsBuenavista Equity Partners

TAAV is a contract development and manufacturing organization (CDMO) that produces neDNA, an enzymatic DNA technology that serves as an alternative to plasmid DNA for manufacturing recombinant adeno-associated viruses (rAAV) used in gene therapy.

BiotechDeep TechHealthtechMedical DevicesSan Sebastian, ES

PartnerJose Mesa· solo GP

Tolerance is a compliance platform that runs continuous automated checks against the NIST 800-171 standard and collects assessor-ready evidence for teams handling Controlled Unclassified Information (CUI).

CybersecurityGovTechSaaS

Co-investorsDorm RoomAmadeus Capital PartnersBen Franklin Technology PartnersBioAdvanceCriteria Bio VenturesEast Innovate+4 more

Tolerance Bio develops therapeutics targeting the thymus—the regulator of immune tolerance—to preserve, restore, and manipulate its function and extend health span.

BiotechDeep TechLongevityPhiladelphia, US

Francisco Leon(Executive Officer, Director)inPhilip Ball(Executive Officer, Director)Justin Vogel(Executive Officer, Director)in

BoardDamia Tormo Carulla(Director)Pablo Cironi(Director)inRobert Goldstein(Director)

Co-investorsCriteria Bio VenturesBen Franklin Technology PartnersBioAdvance

Viralgen provides contract manufacturing services for AAV-based gene therapy, supporting early-phase preclinical and clinical production with a platform designed for regulatory compliance and batch scalability.

Advanced ManufacturingBiotechDeep TechHealthtechMedical DevicesSan Sebastián, ES

Jimmy Vanhove(CEO)

PartnerJose Mesa· solo GP