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Columbus Venture Partners

Venture capital

Valencia · Seed · 1 people tracked

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Investment thesis

Columbus specializes in life science venture investment, focusing on therapeutic and industrial biotechnology products. The firm emphasizes seed-stage funding combined with infrastructure development to build complete value chains, shortening time to exit. The fund combines therapeutic innovation with a track record emphasizing solid returns and clear exit routes designed before investment.

Source: firm website, verified Aug 7, 2026.

Stage
Seed
HQ
Valencia, ES
Leads rounds
Follows
Instruments
Equity
Last 12 months
1 investment
Tracked investments
31

Team · 1 people

from public directories

What they invest in

from 26 of 31 portfolio companies

Biotech ×20Healthtech ×16Deep Tech ×10Medical Devices ×7AI & Machine Learning ×5Advanced Manufacturing ×3Digital Health ×3Cloud Computing ×1

HQs:United States×6Spain×5France×1

Investments · 31 tracked

founders shown can be your intro path
Aura Biosciencesaurabiosciences.comin𝕏NASDAQ: AURA

Aura Biosciences develops Virus-Like Drug Conjugates (VDCs), a platform using Virus-Like Particles conjugated with drugs or loaded with nucleic acids to target solid tumors.

BiotechHealthtechMedical DevicesCambridge, US

Elisabet de los Pinos, Ph.D.(Executive Officer, Director)Michael Wyzga(Executive Officer)Dale Pfost, Ph.D.(Director)Alan E. Walts, Ph.D.(Director)Lewis Geffen(Executive Officer)Peter Wirth(Director)

PartnerJose Mesa· solo GP

Co-investorsAdvent Life SciencesChiesi VenturesDroia VenturesForesite CapitalJazzya InvestmentsMedicxi+4 more

Vivet Therapeuticsvivet-therapeutics.comin𝕏✓ verified

Vivet Therapeutics is a clinical-stage biotechnology company developing recombinant adeno-associated virus (rAAV) gene therapies for rare, inherited metabolic diseases, including Wilson's Disease and cerebrotendinous xanthomatosis.

BiotechHealthtechParis, FR

PartnerJose Mesa· solo GP

Co-investorsHealthCapKurma PartnersNovartis Venture FundRoche Venture FundYsios CapitalEurazeo+1 more

Accipiter Biosciencesaccipiterbio.comJul 2026

Accipiter Biosciences uses computational protein design to develop de novo, single-agent protein therapies that engage multiple cell-surface receptors at once, functioning as agonists.

AI & Machine LearningBiotechDeep TechSeattle, US

Matthew Bick(Executive Officer, Director, Promoter)inJavier Castellanos(Executive Officer, Director, Promoter)Hector De Jesus Rincon Arano(Executive Officer, Promoter)Heather Redman(Director)Randall Schatzman(Director)William Canestaro(Executive Officer)

PartnerJose Mesa· solo GP

Co-investorsArgonautic VenturesPack VenturesWRF Capital

Advantheraadvanthera.comin

PartnerJose Mesa· solo GP

Aletabioaletabio.comin𝕏

Aleta Biotherapeutics develops multi-antigen CAR T Engager (CTE) biologics designed to improve the effectiveness of CAR T cell cancer therapies by increasing target antigen density and preventing cancer escape.

BiotechDeep TechHealthtech

PartnerJose Mesa· solo GP

Algenexalgenex.comin

Algenex develops and produces recombinant proteins and biologics using its CrisBio technology platform, serving animal health, human health, and diagnostics markets.

BiotechDeep TechMedical Devices

PartnerJose Mesa· solo GP

Alto Pharmacyalto.comin𝕏

Alto Pharmacy is a full-service pharmacy that offers patients medication delivery, cost transparency, and pharmacist access.

ConsumerDigital HealthHealthtechSan Francisco, US

PartnerJose Mesa· solo GP

Co-investorsAvego BioScience CapitalBantam GroupCalm VenturesCSC UpshotEvolution VC PartnersFlucas Ventures+7 more

Artax Biopharmaartaxbiopharma.com

Artax Biopharma is a Phase 2 clinical-stage biotechnology company developing first-in-class oral small-molecule Nck modulators that target T cell receptor Signal 1 activation to treat autoimmune diseases without causing immunosuppression.

BiotechHealthtechCambridge, US

Damia Tormo(President, CEO, Treasurer and Founder)Joe Suarez(Executive Officer)Maria Nichol(Executive Officer)Robert W. Armstrong, Ph.D.(Executive Officer, Director)Rob Armstrong(CEO)Jan de Vries, Ph.D.(Director)

PartnerJose Mesa· solo GP

Co-investorsSound BioventuresAdvent Life Sciences

ARTHEx Biotech’s websitearthexbiotech.comin𝕏

Arthex Biotech develops an investigational anti-miR therapeutic targeting an upregulated miRNA for the treatment of myotonic dystrophy, aiming to address the root cause of the disease.

BiotechMedical Devices

PartnerJose Mesa· solo GP

Co-investorsAdBio partnersInvivo Capital PartnersSound Bioventures

AskBioaskbio.comin𝕏

AskBio develops gene therapies based on adeno-associated virus (AAV) technology, with a clinical pipeline targeting central nervous system, neuromuscular, metabolic, and cardiovascular disorders.

BiotechDigital HealthHealthtechMedical DevicesDurham, US

PartnerJose Mesa· solo GP

Co-investorsTPGVida Ventures

Cocoonbiosciencecocoonbioscience.comin

Cocoon Bioscience operates CrisBio, a recombinant protein expression platform that uses insects in a chrysalis (cocoon) state instead of traditional bioreactors to produce enzymes and complex proteins.

BiotechDeep TechNew Materials

PartnerJose Mesa· solo GP

Curapathcurapath.com

Curapath (formerly PTS) is a contract development and manufacturing organization (CDMO) specializing in non-viral drug delivery systems, including polymer and lipid nanoparticle formulations and functional excipients.

Advanced ManufacturingBiotechMedical Devices

PartnerJose Mesa· solo GP

Curve Therapeuticscurvetx.comin

Curve Therapeutics is a drug discovery company that uses a proprietary gene-encoded, high-throughput intracellular platform to screen libraries of cyclic peptides inside live mammalian cells.

AI & Machine LearningBiotechDeep Tech

PartnerJose Mesa· solo GP

Co-investorsEpidarex CapitalPfizer Venture Investments

Deepulldeepull.comin

Deepull develops a multiplex PCR diagnostic system to rapidly identify sepsis-causing pathogens and antibiotic resistance markers directly from blood samples in approximately one hour, targeting hospitals and clinical laboratories.

Medical Devices

Co-investorsAsabys Partners

Digitalsendadigitalsenda.comin

A digital agency offering design and development services—including 3D space configuration, digitizing physical samples into online catalogs, and ticket-sales platforms—for brands across multiple sectors.

Marketing TechSaaS

Highlight Therapeuticshighlighttherapeutics.comin

Highlight Therapeutics develops RNA-based immunotherapies for dermato-oncology, with a lead intra-lesional drug candidate, BO-112, aimed at triggering an immune response against skin cancers.

BiotechHealthtech

PartnerJose Mesa· solo GP

Co-investorsDroia Ventures

Integra Therapeuticsintegra-tx.com

PartnerJose Mesa· solo GP

Co-investorsAdBio partnersInvivo Capital Partners

Juratatfjuratatf.com

Jurata develops thermostable formulations for biologics, vaccines, and advanced therapeutics that reduce or eliminate cold chain and special handling needs.

BiotechDeep TechHealthtech

PartnerJose Mesa· solo GP

Larklark.com

Lark develops an AI-powered health coaching platform that delivers personalized support for chronic disease prevention and management through 24/7 text-based conversations and integration with smart health devices.

AI & Machine LearningDigital HealthHealthtech

Julia Hu(Founder)

PartnerJose Mesa· solo GP

Co-investorsAlpha Intelligence CapitalAsset Management CompanyCrunchFundIPD CapitalJoyance PartnersKing River Capital+5 more

Minoryx Therapeuticsminoryx.comin

Minoryx is a biopharmaceutical company that discovers and develops drug treatments for severe orphan diseases of the central nervous system, such as cerebral adrenoleukodystrophy and Rett syndrome.

BiotechHealthtech

PartnerJose Mesa· solo GP

Co-investorsChiesi VenturesCriteria Bio VenturesFund+Invivo Capital PartnersKurma PartnersRoche Venture Fund+1 more

Nerre Therapeuticsnerretherapeutics.com

PartnerJose Mesa· solo GP

Co-investorsAdvent Life SciencesFountain Healthcare PartnersOrbiMed

Onaona.comin𝕏

Ona provides secure cloud workspaces for running AI coding agents, giving each agent a full cloud development environment with network access, permissions, and runtime controls.

AI & Machine LearningCloud ComputingDeveloper Tools

Co-investorsBright Pixel CapitalCrane Venture PartnersPebblebedPreston-Werner VenturesAlta Life SciencesKorys+1 more

Ona Therapeuticsona-therapeutics.comin𝕏

Ona Therapeutics is a biotechnology company developing first-in-class antibody drug conjugates (ADCs) and antibody therapies targeting the molecular biology of treatment-refractory advanced cancers.

BiotechHealthtech

Co-investorsFund+KorysMérieux Equity PartnersYsios CapitalAlta Life SciencesAsabys Partners+2 more

Quatrelabquatrelab.comin

Quatre Lab (Quality Advanced Therapies Research, S.L.) provides outsourced quality control testing and certification services for advanced therapy medicinal products (ATMPs), helping developers meet regulatory agency requirements for clinical use and market launch.

BiotechDeep TechHealthtech

PartnerJose Mesa· solo GP

Quibimquibim.comin𝕏

Quibim develops cloud-based AI software platforms for medical imaging analysis that extract radiomics features and generate predictive models for healthcare providers and biopharma companies.

AI & Machine LearningHealthtechMedical Devices

PartnerJose Mesa· solo GP

Co-investorsAdara VenturesAmadeus Capital PartnersLifeX VenturesAsabys PartnersGoHub Ventures

Quironsaludquironsalud.es

PartnerJose Mesa· solo GP

Recovidsolutionsrecovidsolutions.com

PartnerJose Mesa· solo GP

Syngoisyngoi.cominacquired by Artis BioSolutions

Advanced ManufacturingBiotechDeep TechWatertown, US

PartnerJose Mesa· solo GP

Co-investorsBuenavista Equity Partners

Taavtaav.comin

TAAV Biomanufacturing Solutions is a CDMO producing enzymatic DNA (neDNA), an alternative to plasmids used as starting material for recombinant AAV (rAAV) production in gene therapy.

BiotechDeep TechHealthtechSan Sebastian, ES

PartnerJose Mesa· solo GP

Tyris TXtyristx.comin

Tyris develops a platform for DNA-based therapies, combining DNA optimisation with non-viral delivery to extend the reach of genetic treatments.

BiotechDeep TechHealthtechValencia, ES

PartnerJose Mesa· solo GP

Viralgenviralgen.comin𝕏

Viralgen is a contract development and manufacturing organization (CDMO) focused exclusively on cGMP AAV-based gene therapy vector manufacturing, using a proprietary suspension triple-transfection platform with the AskBio Pro10 HEK293 cell line.

Advanced ManufacturingBiotechHealthtechSan Sebastián, ES

Jimmy Vanhove(CEO)

PartnerJose Mesa· solo GP

Exits · 2

IPOs and acquisitions across the tracked portfolio

Aura BiosciencesNASDAQ: AURASyngoiacq. by Artis BioSolutions

Portfolio news

latest coverage across their companies

Frequently asked questions

What stage does Columbus Venture Partners invest at?
Columbus Venture Partners invests at the Seed stage.
What sectors does Columbus Venture Partners focus on?
Columbus Venture Partners focuses on Biotech, Healthtech, Medical Devices.
Where is Columbus Venture Partners located?
Columbus Venture Partners is headquartered in Valencia, ES.
Does Columbus Venture Partners lead rounds?
Columbus Venture Partners typically participates in rounds rather than leading them.

Co-investors · 4

Ysios Capital

Ysios Capital is a life sciences investor that finances innovative biotech companies worldwide, providing resources to develop novel therapies for indications with high unmet medical needs.

$5.4M – $21.6M
Advent Life Sciences

Advent Life Sciences is a trans-Atlantic venture capital firm investing in early and mid-stage life sciences companies across the UK, Europe and the USA.

Both backed · 3
Amadeus Capital Partners

Amadeus Capital Partners is a technology investment firm that backs founders building complex, science-led and deep tech businesses, supporting them over the long term as they scale internationally.

Both backed · 1
$50K – $12.7M
Adara Ventures

Adara Ventures is an early-stage technology investor with roughly two decades of experience backing companies built on proprietary data, trust, domain depth and physical systems.

Both backed · 1
$540K – $7.6M

Firms observed investing alongside Columbus Venture Partners, from public investor directories. Shared companies are the overlap with Columbus Venture Partners's recorded portfolio.

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