Ascension Ventures
Corporate VCSaint Louis · Seed–Late Stage · 19 people tracked
Also known as AHV HOLDING COMPANY, LLC
Investment thesis
Ascension Ventures operates a strategic healthcare ecosystem investment model, connecting values-driven health systems with emerging innovators to develop scalable solutions to complex healthcare challenges. It makes venture and growth equity investments in healthcare information technology and services and in medical devices and diagnostics, typically deploying $10-$20 million in aggregate per company. It targets early- to late-stage companies within three to five years of a potential liquidity event, prioritizing solutions with sustainable competitive advantages that improve clinical outcomes, enhance the patient experience, and reduce waste. The firm generates returns for its health-system limited partners and typically requests a board seat or observation rights.
Source: firm website, verified Aug 3, 2026.
Team · 19 people
from the firm's website & public directories
What they invest in
from 57 of 98 portfolio companiesHealthtech ×44Digital Health ×19Medical Devices ×14AI & Machine Learning ×11SaaS ×10Biotech ×8Enterprise Software ×5Hardware ×4
HQs:United States×35United Kingdom×3Australia×1Ireland×1
Investments · 98 tracked
founders shown can be your intro pathEBR Systems develops the WiSE cardiac pacing system, a leadless and physiologic medical device for treating heart failure patients.
HealthtechMedical DevicesSilicon Valley, AU
Allan Will(Executive Chair)John McCutcheon(President, Chief Executive Officer)Dave Stassen(Director)Chris Nave(Director)Richard Riley(Executive Officer)Trevor Moody(Director)
HealthtechMalvern, US
Mark R. Bausinger(Executive Officer)Stephen Campe(Director)Robert Kuhling(Director)Liam Ratcliffe(Director)P. Sherrill Neff(Director)Wilfred Jaeger(Director)
Phreesia offers a digital patient intake platform for healthcare practices, handling patient check-in, information collection, insurance verification, and payment processing before a visit begins.
Digital HealthHealthtechSaaSNew York, US
Edward Cahill(Director)Chaim Indig(Executive Officer, Director)Michael Weintraub(Director)Scott Perricelli(Director)Victor Kats(Director)Charles Kallenbach(Executive Officer)
AristaMD is a technology-enabled clinical services provider that connects primary care physicians with board-certified specialists through eConsults to improve access to specialty care and reduce costs.
Digital HealthEnterprise SoftwareHealthtechSaaSSan Diego, US
Keith Pinter(Chief Executive Officer)Julia Jezmir(President and Chief Medical Officer)Brooke LeVasseur(Executive Officer, Director)Craig Cimini(Director)Brant Heise(Director)
BoardJohn Kuelper(Director)
FraudFinder AI detects and prevents fraud in financial transactions, enabling businesses to safely transact with more consumers while protecting individuals from unfair costs in financial products access.
AI & Machine LearningCybersecurityFintechInsurTechLondon, GB
Risepoint is an education technology company that provides support services to not-for-profit universities and colleges to launch and grow online degree programs.
EdTech
Boston, US
Rick Vandervenne(Director)Seth Blackley(Director)Hugh Merryweather(Executive Officer)Russell K. Richmond(Executive Officer, Director)Matthew Hermann(Director)John Ambrose(Director)
Alignment Health offers Medicare Advantage health insurance plans for Medicare beneficiaries, featuring 24/7 concierge services that schedule doctor appointments, arrange transportation, and answer healthcare questions in-person, in-home, or via mobile.
Digital HealthHealthtechInsurTech
HealthtechCampbell, US
Greg Casciaro(Director)Tara Butler, M.D.(Director)Rob Kuhling(Director)Amr Salahieh(Executive Officer, Director)Henry Chen(Director)Farhad Khosravi(Director)
Bellevue, US
Michael Allen(Director)Victor Kats(Director)Michael Sandoval(Executive Officer, Director)Chris Kelly(Director)Phil Condit(Director)Greg Akers(Director)
BiotechWaltham, US
Farhad Khosravi(Director)Tara Butler(Director)John Pedersen(Executive Officer, Director)Tasneem Dohadwala(Director)Patrick Campbell(Executive Officer, Director)Amarpreet Sawhney(Director)
BardyDx develops the Carnation Ambulatory Monitor (CAM), a lightweight cardiac patch monitor designed for extended-wear ambulatory ECG monitoring that emphasizes P-wave signal clarity.
Digital HealthHealthtechMedical Devices
Mark Querry(Executive Officer)Kevin Nelson, III(Executive Officer)Garheng Kong(Director)Rik Vandevenne(Director)Gust H. Bardy(Executive Officer, Director, Promoter)Alan Levy(Director)
Surest offers an ACA-compliant, employer-sponsored health plan for employers with two or more employees, available on self-funded, fully insured, and level funded bases.
Digital HealthHealthtechInsurTech
Operates an online catalog of laboratory products, research reagents, and supplier references for professional research and laboratory purchasing workflows.
B2B MarketplacesBiotech
Blokur operates a music rights conflict platform that enables music publishers and users to identify and manage ownership disputes and conflicts across songs and rights holders.
Marketing TechMedia & EntertainmentLondon, GB
Cala Health develops non-invasive prescription therapies for movement disorders, starting with a treatment for hand tremor and essential tremor.
Deep TechDigital HealthHealthtechMedical DevicesSilicon Valley, US
Kate Rosenbluth, PhD(President & Chief Innovation Officer)Deanna Harshbarger(Chief Executive Officer)
CardiacBooster is a medical device company developing a high-flow, low-profile percutaneous ventricular assist device (pVAD) for temporary cardiac support in patients with cardiogenic shock and those undergoing high-risk coronary procedures (high-risk PCI).
HardwareHealthtechMedical DevicesGalway, IE
HealthtechForest Lake, US
Karen Shanahan(Director)Ali Behbahani(Director)Steve Goedeke(Executive Officer, Director)William Abraham(Director)Michael DeMane(Director)Jay Graf(Director)
Cedar Gate Technologies, an IQVIA business, provides an end-to-end software platform for value-based care and alternative payment models, covering data management, analytics, and payment administration.
Digital HealthHealthtechSaaS
HealthtechNewton, US
Christopher Hutchison(Executive Officer, Director)Gad Toren(Director)Steven Reeders(Director)Kevin McArdle(Executive Officer)Renard Charity(Director)Anthony Moshal(Director)
Nuwellis is a commercial-stage medical device company that makes the Aquadex SmartFlow ultrafiltration system for cardiorenal fluid management.
HardwareHealthtechMedical Devices
Cofactor Genomics develops predictive diagnostics for cancer immunotherapy using RNA-expression models to characterize tumor microenvironments and predict patient response.
AI & Machine LearningBiotechHealthtechMedical DevicesSt. Louis, US
Dave Messina(Founder/COO)inJarret Glasscock(Founder/CTO)inJarret Glassock(Executive Officer, Director)Matthew A. Ocko(Director)Jon Armstrong(Director)
BoardMark Siegel(Director)
CPS Solutions provides pharmacy management services to hospitals and health systems, including specialty pharmacy, 24/7 telepharmacy support (remote order entry and verification, transitions of care), 340B compliance, rehabilitation, and materials management.
Digital HealthEnterprise SoftwareHealthtech
RejuvenAir, developed by CSA Medical, is a bronchoscopic cryosurgical device that sprays metered doses of liquid nitrogen to destroy damaged airway cells and treat the underlying cause of COPD with Chronic Bronchitis.
HealthtechMedical DevicesLutherville, US
Tracy Marshbanks(Director)Vincent Owens(Director)Ellen Sheets(Executive Officer, Director)Richard Kent(Director)Thomas Snead(Director)Tara Butler(Director)
Emageon is a blog publishing consumer-oriented articles on topics such as smart tech gadgets, social media apps, and online health and wellness guides.
ConsumerMedia & Entertainment
Fullscript is a clinical platform for healthcare providers to manage supplements, lab ordering, personalized care plans, and patient adherence within their existing EHR workflows.
Digital HealthHealthtechWellness & Fitness
Get Well provides a digital patient engagement platform that supports patients across inpatient, outpatient, community, and home care settings using tools like SmartRoom design, a Hospital Journey Manager, AI, and live navigators.
AI & Machine LearningDigital HealthHealthtech
Hallmark builds a workforce operating system for hospitals and health systems that connects fragmented workforce data into a single real-time view, offering tools for demand forecasting, rate and vendor management, compensation automation, benchmarking, and contract management.
Digital HealthHealthtechSaaS
HealthtechMadison, US
Thomas Rockwell Mackie(Director)Roger Chylla(Executive Officer, Director)Greg Robinson(Director)Hao Wang(Executive Officer)Praveen Sinha(Executive Officer, Director)Scott Button(Director)
Help at Home provides relationship-based in-home personal care, primarily serving Medicaid-eligible seniors and people with disabilities to help them age in place.
Digital HealthHealthtechWellness & Fitness
Ingenious Med provides automated billing and revenue cycle management software for health systems, physician practices, and medical groups.
AI & Machine LearningHealthtechSaaS
Instylla develops resorbable liquid embolic agents for interventional radiology and oncology, including the Embrace Hydrogel Embolic System and the Tembo Embolic System used to embolize hypervascular tumors and occlude peripheral blood vessels.
BiotechHealthtechMedical DevicesBedford, US
Sean Boyle(Chief Executive Officer)
IMO Health builds a clinician-curated medical terminology, ontology, and knowledge graph, along with software products that capture, standardize, and normalize clinical data for AI, coding, billing, and analytics use cases.
AI & Machine LearningDigital HealthHealthtech
BiotechOlivette, US
James McGorry(Director)Scott Gill(Executive Officer)Joseph Feder, Ph.D.(Director)James M. Stolze(Director)George Dunbar(Executive Officer, Director)William J. Maloney, M.D.(Director)
Neurolutions develops IpsiHand, a brain-computer interface therapy system for stroke survivors to improve arm and hand movement at home.
AI & Machine LearningHealthtechMedical Devices
Localistico is a local marketing and analytics platform that helps brick-and-mortar businesses get discovered by customers through search engines, maps, and AI assistants, while managing their online presence and reputation at scale.
AI & Machine LearningMarketing TechRetail Tech
Merit Medical Systems designs, develops, manufactures and markets medical devices for interventional and diagnostic procedures.
HealthtechMedical Devices<UNKNOWN>, US
Mindpath provides in-person and online psychiatry and therapy services, including medication management, individual/couples/family therapy, and TMS treatment for conditions such as depression, anxiety, ADHD, and OCD.
Digital HealthHealthtechMental Health
Frequently asked questions
- What stage does Ascension Ventures invest at?
- Ascension Ventures invests at the Seed, Series A, Series B, Series C, Growth, Late Stage stages.
- What is Ascension Ventures's typical check size?
- Ascension Ventures typically writes checks of $10M – $20M.
- What sectors does Ascension Ventures focus on?
- Ascension Ventures focuses on Digital Health, Enterprise Software, Healthtech, Medical Devices.
- Where is Ascension Ventures located?
- Ascension Ventures is headquartered in Saint Louis, US.
- Does Ascension Ventures lead rounds?
- Ascension Ventures typically participates in rounds rather than leading them.
Media · Podcasts & interviews
featuring the teamSean Cheng, Ascension Ventures - AMOI Studio Interview | LSI USA ‘23
LSI - Life Science Intelligence™ · Sean Cheng
Images
Co-investors · 36
New Enterprise Associates (NEA) is a venture capital firm that invests in and provides long-term support to founders building new companies.
SV Health Investors is a healthcare-focused private equity and venture capital investment platform managing specialized and diversified funds across biotechnology, healthcare growth equity, and medtech.
Echo Health Ventures is a strategic venture capital and growth equity investor that partners with health care companies to help build and scale their innovations nationally.
GV (formerly Google Ventures) is a venture investment firm that backs founders across many industries, aiming to build long-term relationships and support companies across multiple stages and milestones.
Menlo Ventures is a venture capital firm that backs transformative, early-stage technology companies reshaping how people live and work.
DCVC (Data Collective) is a venture capital firm that backs founders building companies which apply technology to major challenges across areas such as energy, biotech, agriculture, and machine learning.
CapitalG is Alphabet's independent growth fund, investing in growth-stage consumer and enterprise technology companies and providing hands-on operational and strategic support drawn from Google's scaling experience.
.406 Ventures is an early-stage venture capital firm that partners with founders building companies in healthcare, data and AI, and cybersecurity.
CVS Health Ventures is the corporate venture arm of CVS Health, backing innovative companies focused on transforming health care.
Alumni Ventures (AV) is a venture firm that gives accredited individual investors access to professionally managed, diversified venture portfolios by co-investing alongside leading lead VC firms. It offers annual funds, syndicate deal-by-deal investing, and various investor clubs.
SOSV is a deep tech venture capital firm that makes first-check pre-seed investments and follow-on rounds in startups focused on human and planetary health, providing lab space and hands-on support at its US locations.
Oak HC/FT is a growth equity firm that partners with founders building companies in healthcare and financial services, with a focus on enterprise technology and AI.
▶24 more co-investors
Polaris Partners7percent VenturesComcast VenturesLa FamigliaFlucas VenturesVisionaries ClubGE VenturesJump CapitalFlexcap VenturesStrata Capital PartnersAllen Institute for Artificial Intelligence Incubator (AI2)World FundFirefly HealthHaatchCornerstone VCFuture Planet CapitalForce Over Mass CapitalEndeavor8FinTLV VenturesQVenturesSatori CapitalUndeterred CapitalElbow Beach Capital2050 Capital
Firms observed investing alongside Ascension Ventures, from public investor directories. Shared companies are the overlap with Ascension Ventures's recorded portfolio.
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