/Investor DB

California Innovation Fund

Venture capital

Berkeley · Seed–Growth · 19 people tracked

Also known as CALIFORNIA INNOVATION

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Investment thesis

California Innovation Fund focuses on backing promising startups that emerge from UC Berkeley and other leading entrepreneurial universities around the world. The firm describes its approach as 'powering the flywheel of innovation' — investing in university-affiliated ventures and leveraging their outcomes to fund and support the next generation of entrepreneurs. Its model ties academic entrepreneurial ecosystems to venture investment.

Source: firm website, verified Oct 2, 2026.

Stage
Seed–Growth
HQ
Berkeley, US
Leads rounds
Leads
Instruments
Equity
Founded
2021
Last 12 months
1 investment
Tracked investments
36
Unicorns
1
Acquisitions
1

Team · 19 people

from the firm's website & curated & public directories
Mateo Bueno· Partnerin𝕏
Ashley Gould· Investorin
Liz Feinsteinin
Roger Bensonin
Vanessa Kahkesh· Investorin𝕏

What they invest in

from 24 of 36 portfolio companies

AI & Machine Learning ×11Biotech ×8Healthtech ×7Medical Devices ×7Deep Tech ×6SaaS ×6Digital Health ×4Cybersecurity ×3

HQs:United States×18

Who they back

founder profiles across 22 portfolio companies
32%
solo founders
7 of 22 mapped founding teams
27%
repeat founders
of 26 founders with career history

Founding team size:solo founder×72 founders×93 founders×34+ founders×3

Where their founders studiedfrom 26 founders with education data

University of California, Berkeley ×6University of California, Berkeley, Haas School of Business ×4Duke University ×2Stanford University Graduate School of Business ×2The London School of Economics and Political Science (LSE) ×2University of California, San Francisco ×2

What their founders studiedfrom 27 founders with field-of-study data

Engineering ×8Life Sciences ×8Computer Science ×5Economics ×4Business & Management ×3Humanities ×3Chemistry ×2

Where their founders worked beforefrom 26 founders with career history

Stanford University ×3University of California, Berkeley ×3Google ×2

Accelerator rootsportfolio companies that came through a program

Y Combinator ×3

12 founders hold a PhD · 4 hold an MBA (of 29 with degree data)

Investments · 36 tracked

founders shown can be your intro path

By year:2025 · 32024 · 22023 · 16 dated

Answers AIanswersai.aiin

Enabling personalized education worldwide.

Bri Wilburn(Founder)inMamoun Debbagh(Founder)in

Co-investorsArray Ventures Management LlcCAL InnovationDeVCDorm Room

Blingsblings.ioin

Blings provides a video personalization platform that dynamically updates content in real-time by pulling data from customer CRM and database systems, ensuring each viewer sees customized video experiences.

AI & Machine LearningMarketing TechSaaS

Co-investorsCAL InnovationHanaco Venture CapitalVertex Ventures IsraelVertex Ventures

Breatheasy MIISTmiisttherapeutics.cominFeb 2025

Miist develops inhaled microparticle therapeutics that deliver medicine to the bloodstream in 30 seconds, targeting conditions like migraine, pain, and anxiety where rapid onset is critical.

BiotechDigital HealthHealthtechMedical DevicesAlameda, US

Eric Ezerins(Cofounder, Head of Technology)inDalton Signor(Cofounder, CEO)inRandy Krebs(Executive Officer)Jeffrey Schuster(Chief Technology Officer)inEvan Alfano(Director)

Co-investorsCAL InnovationEntrepreneur FirstFREEFLOWThe Innovation SpaceRefactor Capital

Catena Biosciencescatenabio.cominMay 2024

CatenaBio develops precision conjugation technology using native amino acids to enable biotherapeutic fusions of small molecules, nucleic acids, enzymes, and cells.

BiotechDeep TechHealthtechMedical DevicesBerkeley, US

Marco Lobba(Founder)inMatthew Francis(Founder)inGeo Guillen

Co-investorsCivilization Ventures Management, LlcCreative Destruction Lab (CDL)FREEFLOWIaso VenturesJude GomilaLongeVC+14 more

Cooler Headscoolerheads.comin

Cooler Heads develops scalp cooling technology to prevent hair loss in cancer patients undergoing chemotherapy.

HealthtechMedical DevicesSan Diego, US

Kate Dilligan(Founder & CEO)in

BoardMaria Gonzalez-Blanch(Director)inMICHAEL SCHOTZINGER(Director)inLIZ TODIA(Director)LIZ ZAMBORY(Director)inJASON PESTERFIELD(Director)in

Co-investorsAd Astra VenturesAloft VCAstiaBacchus Venture CapitalCAL InnovationGolden Seeds+6 more

EditPepinDec 2024

A Berkeley spinout developing a new generation of medicines for the brain and other hard-to-treat tissues using breakthrough science from UC Berkeley and the Innovative Genomics Institute.

BiotechBerkeley, US

Ross Wilson(Executive Officer, Director, Promoter)Dana Foss(Executive Officer, Director, Promoter)in

BoardJaromir Tesar(Director)

Co-investorsCAL Innovation

EdVisorly, Inc.edvisorly.comin𝕏

EdVisorly is an AI-based enrollment platform for higher education institutions, used to manage admissions and enrollment operations.

AI & Machine LearningEdTechSaaS

Manny S.(Founder)inManny Smith(Founder)Christine Wyatt(Chief Operating Officer)inLandon Lewis(Chief Technology Officer)in

Co-investorsCAL InnovationDorm RoomMotley Fool VenturesPotencia VenturesSilicon ValleyBlack Operator

Eko Healthekohealth.comin𝕏

Eko develops FDA-cleared digital stethoscopes and AI-powered software that enables healthcare professionals to detect and diagnose cardiovascular disease with greater accuracy.

AI & Machine LearningDigital HealthHealthtechMedical Devices

Connor Landgraf(Co-Founder and CEO)inTyler CrouchinJason Bellet(Co-Founder and Chief Business Officer)in

Co-investorsQuesta CapitalHighland Capital PartnersArtis VenturesBetter Ventures Central LlcCAL InnovationDigiTx Partners LLC+14 more

Encellinencellin.comin𝕏

Encellin develops next-generation therapies for patients with chronic unmet clinical needs, using technology originating from Dr.

BiotechDeep TechHealthtechMedical DevicesSan Francisco, US

Tejal Desai(Technology Expert, Founder)Ronald Martell(Strategic Advisor, Founder)inCrystal Nyitray(Executive Officer, Director, Promoter)inGrace Wei(Executive Officer, Director, Promoter)in

BoardMaria del Consuelo Valverde(Director)

Co-investorsEndurance28Evolution VC PartnersHow Women InvestITERATIVEMetaplanetSand Hill Angels+4 more

Engage Bioengagebio.cominAcquired

EngageBio develops DNA-based medicines using proprietary non-viral delivery technology to achieve extended therapeutic expression from a single dose with low manufacturing complexity.

BiotechDigital HealthHealthtechSan Francisco, US

Will Olsen(Founder)inKathryn Kwant

Co-investorsCAL InnovationMetaplanetSciFoundersVentureSouqWorldQuant VenturesY Combinator+9 more

FreeWire Technologiesfreewiretech.com

Android for EV charging - software solution that works with any 3rd party hardware

CleantechEnergyMobility & TransportationSan Leandro, US

Arcady Sosinov(Executive Officer, Director)

BoardChad Bown(Director)Michael Mahan(Director)Richard Steele(Director)Gary Moskovitz(Director)

Co-investorsAlumni VenturesBlue Bear Capital PartnersFoothill VenturesMarketX VenturesMomenta VenturesRed Sails Investment+10 more

Gcgc.aiin𝕏

GC AI is an AI platform built for corporate in-house legal teams, letting lawyers draft, review, and analyze legal documents, research case law, and run contract-review workflows.

AI & Machine LearningLegalTechSaaSSan Mateo, US

Cecilia Ziniti(Founder)inBardia Pourvakil(Founder)inCecilia Ziniti Bardia Pourvakil(Founder)

Co-investorsAZURO CAPITAL VENTURESFellowsFJ LabsNorthzoneScale Venture PartnersTech Square Ventures+4 more

Kytedrivekyte.com𝕏Defunct

Kyte was an on-demand car rental startup that delivered and picked up rental vehicles at customers' locations, aiming eventually to support teleoperated and autonomous vehicle delivery.

Co-investorsAmplo VenturesFJ LabsFlucas VenturesFundersClubRosecliff Ventures1984 Ventures Management, Llc+6 more

LILTlilt.com

LILT provides a multilingual AI platform that uses agentic AI models combined with expert human verification to translate and localize enterprise content such as product materials, technical documentation, and marketing campaigns.

AI & Machine LearningEnterprise SoftwareSaaSSan Francisco, US

John DeNero(Founder)inSpence Green(Founder)in

BoardWilliam Coughran(Director)Mark Rostick(Director)in

Co-investorsCAL InnovationClear VenturesIn-Q-TelIntel CapitalKube VCRedpoint Ventures+3 more

Mammoth Biosciencesmammoth.bioin𝕏

Mammoth Bio develops technology to read and write the code of life, operating in the biotechnology sector.

BiotechDeep TechMedical DevicesBrisbane, US

Jennifer Doudna(Founder)inTrevor Martin(Founder)inJanice Chen(Founder)inLucas Harrington(Founder)inAshley Tehranchi(Founder)in

BoardUrshit Parikh(Director)

Co-investors8VCBerkeley FrontierDecheng CapitalForesite CapitalMayfield FundMission Bay Capital+12 more

Modelwisemodelwise.ai

Modelwise develops Paitron, software that automates safety analysis such as FMEA for critical hardware systems using model-based failure propagation, AI, and qualitative models.

AI & Machine LearningDeep TechSaaS

Co-investorsAtlas Ventures (UK)Emerging Ventures

Prosperprosper.comin𝕏

Prosper operates an online lending marketplace connecting borrowers with investors, offering personal loans up to $50,000 (issued by WebBank), a credit card, and investment products that let individuals invest in consumer loans.

FintechMarketplacesSan Francisco, US

David Kimball(Founder)inChris Larsen(Founder)John Witchel(Founder)

Co-investorsAkkadian VenturesBreyer CapitalEmergence Capital PartnersF-Prime CapitalFenway Summer VenturesFrancisco Partners+9 more

Resemble AIresemble.aiin𝕏

Resemble develops generative voice models and synthetic speech technology, alongside deepfake detection capabilities.

AI & Machine LearningCybersecurityDeep TechEnterprise SoftwareMedia & Entertainment

Zohaib Ahmed(Founder)inSaqib Muhammad(Founder)in

Co-investorsBerkeley FrontierBetaworksBright Pixel CapitalCAL InnovationComcast VenturesGlobal Brain+13 more

Sequinsequincard.comin𝕏

Sequin offers a debit card and financial product aimed at women, with a focus on building credit and financial education.

ConsumerFintech

Vrinda Gupta(Founder)in

Co-investorsDorm RoomEmles Venture PartnersFirst Check VenturesScout FundScribble VenturesAbstract Ventures+9 more

SixMapsixmap.ioin

SixMap provides a cyber defense platform that discovers digital assets across IPv4 and IPv6 using its 6Gen computational mapping algorithm and continuously scans all ports on each host to identify exposures.

AI & Machine LearningCybersecurityEnterprise SoftwarePasadena, US

Jason Kaplan(Chief Executive Officer)inGregory Levesque(Director)Austin Murdock(Chairman, Chief Scientist, and Founder)inWilliam Jr. Murdock(Executive Officer, Director)

BoardRobert Ackerman(Director)inMichael Janke(Director)in

Co-investorsCAL InnovationDataTribeIAG Capital Partners

Space Kineticspacekinetic.comin

Space Kinetic develops technology to enable frequent, low-cost maneuvering and operations for spacecraft and space systems.

Deep TechHardwareSpace Tech

Scott Ziegler(Founder)in

Co-investorsBackswing VenturesBalerion Space VenturesCAL InnovationIndustrious VenturesUP PartnersCerraCap Ventures

Stylus Medicinestylusmedicine.comin

Stylus Medicine develops in vivo genetic medicines using engineered recombinases, with initial focus on creating CAR-T therapies delivered via lipid nanoparticles for oncology, autoimmune, and genetic diseases.

BiotechDigital HealthMedical Devices

Michael C. Bassik, Ph.D.(Scientific Founder)Emile Nuwaysir, Ph.D.(Chairman & Chief Executive Officer)inJason Fontenot, Ph.D.(Chief Scientific Officer)Ami Bhatt(Founder)Lacramioara Bintu(Founder)Michael Bassik(Founder)

Co-investorsBrainstorm VenturesCAL InnovationKhosla VenturesNeva Sgr.RA CapitalTachyon Ventures+1 more

Synviviasynvivia.comDec 2023

Synvivia engineers molecules designed to reprogram cells.

AI & Machine LearningBiotechHealthtechSan Francisco, US

Gabriel Lopez(CEO)in

Co-investorsCAL InnovationCreative VenturesMetaplanetThundermark CapitalY CombinatorFor Good Ventures+3 more

TransCryptstranscrypts.comin𝕏Oct 2025

TransCrypts is a blockchain-based platform for verifying and sharing employment, health and educational credentials.

CybersecurityData & InfrastructureFintechNewark, US

Zain Zaidi(Founder)inZain Z(Founder)Ali Zaheer(Founder)

Co-investorsAlpha EdisonAlumni VenturesAtland VenturesBeyond CapitalCAL InnovationFaction+13 more

Windfall Datawindfall.comin𝕏

Windfall is a people intelligence and AI company that provides access to people data along with propensity modeling and machine learning to help go-to-market teams prioritize resources and engage the right prospects.

AI & Machine LearningData & InfrastructureSaaSSales Tech

Arup Banerjee(Founder)inDaniel Stevens(Founder)in

Co-investorsBullpen CapitalBonfire VenturesGreat Oaks Venture CapitalValuestream VenturesFortress Investment GroupKohala Ventures

Your360 AIyour360.aiin𝕏Sep 2025

Your360 AI runs interview-based 360-degree feedback programs where an AI coach conducts voice conversations with employees and their feedback providers, then synthesizes the results into coaching themes and a prioritized growth plan.

AI & Machine LearningFuture of WorkHR TechSan Francisco, US

Jared Seth Goralnick(Executive Officer, Director, Promoter)Sergio Kaszczyszyn(Executive Officer, Director, Promoter)inRenata Elisabeth Bell(Executive Officer, Director, Promoter)

Co-investorsCAL InnovationCapital Factory

Other

Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.

CalyxCatenaCatena BioscienceMammothMiistProsper MedicalSelva TherapeuticsVivereVivere OncotherapiesYeast Bay Bio

Portfolio news

latest coverage across their companies

Frequently asked questions

How many investments has California Innovation Fund made?
California Innovation Fund has 36 tracked investments, 1 of which have exited, including 4 dated in the last 24 months.
What stage does California Innovation Fund invest at?
California Innovation Fund invests at the Seed, Series A, Growth stages.
What sectors does California Innovation Fund focus on?
California Innovation Fund focuses on AI & Machine Learning, Biotech, Cleantech, Cybersecurity, Digital Health, EdTech, Fintech, LegalTech, Mobility & Transportation, Sector Agnostic, Space Tech.
Where is California Innovation Fund located?
California Innovation Fund is headquartered in Berkeley, US.
Does California Innovation Fund lead rounds?
Yes, California Innovation Fund leads investment rounds.
Who does California Innovation Fund co-invest with?
California Innovation Fund most often shares deals with CAL Innovation, Dorm Room, Metaplanet, among 149 tracked co-investors.

Media · Podcasts & interviews

featuring the team

Bryce Gilleland - GP - Cal Innovation Fund II California Innovation Fund

Charles Cormier - Founder Wisdom Podcast · Bryce Gilleland

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