Nested Therapeutics
Founded 2021 · 16 employees on LinkedIn · 6 known investors
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Nested Therapeutics is a precision oncology company developing small-molecule cancer therapeutics by identifying overlooked driver mutations and novel binding pockets through a drug discovery platform combining genomics, computational biophysics, machine learning, and chemical biology. Its lead program, NST-628, is a brain-penetrant pan-RAF/MEK molecular glue in Phase 1 trials for MAPK-driven solid tumors, alongside a mutation-selective p53-pathway program.
Founders & leadership
Nested Therapeutics was founded in 2021 by Arvin Dar, Kevan Shokat, and Klaus Hoeflich.


Investors · 6
How we know: Versant Ventures's portfolio page · the company's own site · a partner's Signal profile · Not right? Tell us
How we know: Foresite Capital's portfolio page · press coverage · Not right? Tell us
How we know: Sixty Degree Capital's portfolio page · Not right? Tell us
How we know: funding news · press coverage · Not right? Tell us
How we know: funding news · press coverage · Not right? Tell us
How we know: press coverage · Not right? Tell us
Funding
SEC filings, press & company announcements- Undisclosed amountseries AOct 2022Source ↗
Source: company announcements and press reports — follow each round's link for the claim.
Frequently asked questions
- What does Nested Therapeutics do?
- Nested Therapeutics is a precision oncology company developing small-molecule cancer therapeutics by identifying overlooked driver mutations and novel binding pockets through a drug discovery platform combining genomics, computational biophysics, machine learning, and chemical biology. Its lead program, NST-628, is a brain-penetrant pan-RAF/MEK molecular glue in Phase 1 trials for MAPK-driven solid tumors, alongside a mutation-selective p53-pathway program.
- Who founded Nested Therapeutics?
- Nested Therapeutics was founded by Arvin Dar, Kevan Shokat, Klaus Hoeflich in 2021.
- Who are Nested Therapeutics's investors?
- Nested Therapeutics's investors include Versant Ventures, Foresite Capital, Sixty Degree Capital, Cowen Healthcare Investments, Goldman Sachs, Section 32.







