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Nested Therapeutics

Founded 2021 · 16 employees on LinkedIn · 6 known investors

Find your way into Nested Therapeutics

665 people in our graph share verified history with the Nested Therapeutics team — schools, employers, funds. One of them is your warm intro.

Dan Lynchunlockedknows Klaus Hoeflich · together at Blueprint Medicines (overlapped)
×10knows the team · via University of Toronto
knows the team · via Blueprint Medicines

Nested Therapeutics is a precision oncology company developing small-molecule cancer therapeutics by identifying overlooked driver mutations and novel binding pockets through a drug discovery platform combining genomics, computational biophysics, machine learning, and chemical biology. Its lead program, NST-628, is a brain-penetrant pan-RAF/MEK molecular glue in Phase 1 trials for MAPK-driven solid tumors, alongside a mutation-selective p53-pathway program.

Founders & leadership

Nested Therapeutics was founded in 2021 by Arvin Dar, Kevan Shokat, and Klaus Hoeflich.

ADArvin Dar
Arvin DarinCo-founder & Board Observer
KS
Kevan ShokatScientific Co-founder
KHKlaus Hoeflich
Klaus HoeflichinCo-founder & former Chief Scientific OfficerCo-founder and former Chief Scientific Officer of Nested Therapeutics, a precision oncology company. Hoeflich has advanced cancer drug candidates through target discovery, IND submission, and clinical development, with experience in R&D leadership and establishing academic and industry partnerships.
DMDarrin Miles
Darrin MilesinChief Executive Officer
PKPhilip Komarnitsky
Philip KomarnitskyinChief Medical Officer
TWTanja Weber
Tanja WeberinChief Business Officer

Investors · 6

Funding

SEC filings, press & company announcements

Source: company announcements and press reports — follow each round's link for the claim.

In the news

Frequently asked questions

What does Nested Therapeutics do?
Nested Therapeutics is a precision oncology company developing small-molecule cancer therapeutics by identifying overlooked driver mutations and novel binding pockets through a drug discovery platform combining genomics, computational biophysics, machine learning, and chemical biology. Its lead program, NST-628, is a brain-penetrant pan-RAF/MEK molecular glue in Phase 1 trials for MAPK-driven solid tumors, alongside a mutation-selective p53-pathway program.
Who founded Nested Therapeutics?
Nested Therapeutics was founded by Arvin Dar, Kevan Shokat, Klaus Hoeflich in 2021.
Who are Nested Therapeutics's investors?
Nested Therapeutics's investors include Versant Ventures, Foresite Capital, Sixty Degree Capital, Cowen Healthcare Investments, Goldman Sachs, Section 32.