OS Fund
Venture capitalPark Ridge · Pre-Seed–Series A · 5 people tracked
Investment thesis
Founded by Bryan Johnson, invests in platforms and enabling technologies supporting inventors and scientists building programmable-biology solutions to rewrite life's operating systems and benefit humanity.
Team · 5 people
from public directories
What they invest in
from 23 of 31 portfolio companiesBiotech ×16Healthtech ×13Deep Tech ×11AI & Machine Learning ×9Medical Devices ×5AgTech ×2Climate Tech ×2Cloud Computing ×2
HQs:United States×14Canada×1
Investments · 31 tracked
founders shown can be your intro path
Ginkgo Bioworks builds autonomous labs and offers cell-programming and bioengineering services for the biopharma, agriculture, and industrial biotech markets.
AgTechAI & Machine LearningBiotechDeep TechHealthtechBoston, US
Jason Kelly(Founder)inAustin Che(Founder)inTom Knight(Founder)inBarry Canton(Founder)inReshma Shetty(Founder)in
BoardReshma Sohoni
Co-investors11.2 CapitalB3 HoldingCannage CapitalCool Climate CollectiveDCVC (Data Collective)Designer Fund+15 more
3T Biosciences develops TCR-based immunotherapies for cancer using a proprietary platform that combines machine-learning algorithms with immunological research to identify and validate T cell receptor targets.
AI & Machine LearningBiotechHealthtechMedical DevicesSouth San Francisco, US
K. Christopher GarciaMarvin Gee(Founder)in
Co-investorsAsset Management CompanyCRV (Charles River Ventures)Westlake Village BioPartnersMenlo VenturesStarlight Ventures
A-Alpha Bio uses synthetic biology and machine learning to measure, predict, and engineer protein-protein interactions for pharmaceutical discovery and development.
AI & Machine LearningBiotechDeep TechSeattle, US
David Younger, PhD(Chief Executive Officer & Co-Founder)Randolph Lopez, PhD(Chief Technology Officer & Co-Founder)David Younger(Executive Officer, Director, Promoter)
Co-investorsAngel Collective Opportunity FundBreakout VenturesFarvatn VentureLux CapitalMadrona Venture GroupBoom Capital Ventures
Arzeda designs proteins and metabolic pathways using computational tools, including its Archytas protein design software and Scylax metabolic pathway design software.
AI & Machine LearningBiotechDeep TechFoodTechNew MaterialsSeattle, US
Alexandre Zanghellini(Co-Founder & Chief Executive Officer)Eric Althoff(Executive Officer, Director, Promoter)Bill Baum(Director)Andrew Ban(Executive Officer)Daniela Grabs(Executive Officer)David Baker
Co-investorsCirculate CapitalSofinnova PartnersSustainable Conversion VenturesFall Line CapitalUniversal Materials Incubator
Atomwise uses artificial intelligence and machine learning to discover novel small-molecule drugs, with a current focus on developing treatments for immune and inflammatory diseases.
AI & Machine LearningBiotechDeep TechSan Francisco, US
Izhar Wallach(Executive Officer, Director)Abraham Heifets(Executive Officer, Director, Promoter)Yan Zhao(Executive Officer)Stephen Worland(Executive Officer, Director)
BoardRobert Mittendorff(Director)inAdam Seabrook(Director)in
Co-investorsAurum Venture PartnersB Capital GroupCerity Partners VenturesCreative Destruction Lab (CDL)Draper AssociatesThreshold Ventures+5 more
Catalog is a platform for independent musicians to share and sell their music, letting artists earn 100% of digital download sales with no marketplace fees and split revenue automatically with collaborators.
Creator EconomyMarketplacesMedia & Entertainment
Co-investors1confirmationInflection.xyzKindred VenturesDCVC (Data Collective)New Enterprise Associates (NEA)SOSV+1 more
Biomemory develops DNA-based data storage systems for data centers, offering an alternative storage tier optimized for long-term archival, density, and energy efficiency.
Climate TechData & InfrastructureDeep Tech
Co-investorsCivilization Ventures Management, LlcFifty YearsPrefix CapitalZ Venture CapitalCantos VenturesPathbreaker Ventures+1 more
Elysium develops healthcare products focused on aging research and healthy aging rather than disease treatment.
HealthtechLongevityWellness & Fitness
Leonard Guarente, Ph.D.(Co-founder & Chief Scientist)
Co-investorsBreyer CapitalSprint VcThe Venture Collective
Emerald Cloud Lab (ECL) provides remote, cloud-based access to a life science research laboratory, letting researchers run and automate experiments and workflows without a physical lab.
BiotechCloud ComputingDeep Tech
Co-investorsBlue Ivy VenturesGigafundSchooner CapitalSoundproof Ventures
Emulate develops Organ-Chip technology, including 30+ organ models such as liver, brain, and other human tissue chips, used for human-based preclinical drug safety and toxicity testing.
BiotechDeep TechHealthtech
Co-investors+ND CapitalAlwyn CapitalStray Dog CapitalStarlight Ventures
GRObio (GRO Biosciences) develops protein therapeutics using non-standard amino acids (NSAAs) via its GRO platform, aiming to improve protein potency, stability, and function.
BiotechDeep TechHealthtech
Co-investorsLeaps by BayerREDMILEDreamers VCDigitalis Ventures
Helix Nanotechnologies develops mRNA-based therapeutics for disease treatment and environmental applications, currently advancing a COVID-19 vaccine candidate for immunocompromised patients and testing interventions targeting climate challenges.
AI & Machine LearningBiotechHealthtechBoston, US
Nikolai Eroshenko(Founder/CSO)in
Co-investorsBeast VenturesChampion Hill VenturesFifty YearsLifeline VenturesLongeVCMetaplanet+6 more
The site is a Vietnamese-language affiliate/review portal that ranks and rates online lottery ("lô đề") betting operators, offering comparisons of payout ratios, licensing, payment methods, and security.
ConsumerHealthtechMedia & EntertainmentMedical DevicesKitchener, CA
Moufeed Kaddoura(Founder/CEO)inEric Blondeel(Founder/| CTO)in
Co-investorsFifty YearsMetaplanetUpslope VenturesY Combinator1517BoxOne Ventures+1 more
Lucira Health manufactures portable diagnostic devices that connect to smartphones to test bodily fluids for infectious diseases, enabling rapid results outside of clinical settings.
BiotechHealthtechMedical DevicesEmeryville, US
Debkishore Mitra(Founder)inJohn R. Waldeisen(Director)
BoardErik T. Engelson(Executive Officer, Director)Justin Butler(Director)Tuff Yen(Director)Steve Tablak(Director)
Co-investors11.2 CapitalForesite CapitalShangBay Capital LLCY Combinator
Lygos uses genetically engineered microorganisms to produce industrial chemicals from sugar feedstocks, focusing on compounds where fermentation offers cost advantages compared to fossil fuel-based manufacturing.
Climate TechHealthtechSan Francisco, US
Eric Steen(Founder/CSO)inJeffrey A. Dietrich(Executive Officer, Director)Jay D. Keasling(Director)
BoardLeonard Katz(Director)
Co-investorsFifty YearsFundersClubLG Technology VenturesY Combinator10x FoundersFirst Round Capital+1 more
Matternet designs, builds, and operates autonomous drone delivery networks for fast, low-cost, zero-emission package delivery, with a system holding FAA Type Certification.
HardwareLogistics & Supply ChainRobotics
Co-investorsComet LabsDRONE FUNDFlucas VenturesLocus VenturesSony Ventures Corporation
Co-investorsID345Sun Mountain CapitalHumboldt
IBM is a global technology company whose business spans enterprise software (including Red Hat, HashiCorp, and Confluent), IT infrastructure such as mainframes, servers, and storage, and IT consulting services.
AI & Machine LearningCloud ComputingEnterprise SoftwareQuantum ComputingArmonk, US
Jit Saxena(Founder)Arvind Krishna(Chairman, President and CEO)
Co-investorsbacktrace capitalBallistic VenturesBantam GroupBessemer Venture PartnersBrightspark VenturesCorsa Ventures+14 more
Co-investorsLaunchCapital
Pivot Bio develops agricultural innovations focused on transforming farming practices through microbiology and genetics.
AgTechBiotechEmeryville, US
Alvin Tamsir(Executive Officer, Director)Karsten Temme(Executive Officer, Director)
BoardRoger Wyse(Director)John Hamer(Director)inMatt Ocko(Director)in
Co-investorsCongruent VenturesDCVC (Data Collective)G2 Venture PartnersK3 VenturesManta Ray VenturesPrelude Ventures+5 more
Strateos operates a cloud lab platform offering high-throughput laboratory automation as a service, letting scientists design, run, and analyze experiments remotely through a web browser.
AI & Machine LearningBiotechRobotics
Co-investorsDCVC (Data Collective)Harmonix FundLux CapitalDolby Family VenturesSilicon Badia
Synthego develops CRISPR gene-editing and molecular diagnostics products, including custom CRISPR editors in mRNA or protein formats, base editors, and cell-free protein and RNA production systems.
BiotechDeep TechHealthtechMedical DevicesRedwood City, US
Paul John Dabrowski(Executive Officer, Director)Michael Jakub Dabrowski(Executive Officer, Director)
BoardDrew Oetting(Director)inScott Nolan(Director)in
Co-investorsAAF Management Ltd.AME Cloud VenturesDeclaration PartnersFounders FundKhosla VenturesMenlo Ventures+4 more
San Francisco, US
Shashank Samala(Cofounder)
Co-investorsGrit VenturesKeiretsu ForumLux CapitalPoint72 VenturesSQN Venture Partners, LLCUncork Capital
Truvian Sciences (Truvian Health) develops an automated benchtop diagnostic system for blood testing.
BiotechDigital HealthHealthtechMedical DevicesSan Diego, US
Dena Marrinucci(Co-Founder & Chief Operating Officer)Michael J. Mina(Chief Medical and Strategy Officer)
Co-investorsDns CapitalGreatPoint VenturesWittington VenturesDomain AssociatesMedical Excellence Capital
Verge Labs builds AI models trained on multimodal human patient data to predict drug targets and patient populations for clinical development, primarily in neuroscience and central nervous system (CNS) disease.
AI & Machine LearningBiotechDeep TechDigital HealthHealthtechSan Francisco, US
Alice Zhang(Founder/CEO)inJason Chen(Cofounder)Emily Ripka(Head of Product & Engineering)
Co-investorsBOLD LongevityGreat Oaks Venture CapitalKarlin VenturesLifeforce CapitalTenmileWorldQuant Ventures+4 more
Co-investorsAmino CapitalOlive Tree CapitalMorpheus Ventures
Exits · 1
IPOs and acquisitions across the tracked portfolioGinkgo BioworksNYSE: DNA
Portfolio news
latest coverage across their companiesCatalog · billboard.com · Aug 14, 2026
Netezza · pulse2.com · Jul 18, 2026
Pivot Bio · pivotbio.com · Jul 1, 2026
Ginkgo Bioworks · kavout.com · Jun 21, 2026
Matternet · stattimes.com · May 29, 2026
Verge Genomics · science.org · Dec 17, 2025
A-Alpha Bio · nasdaqprivatemarket.com · Jun 27, 2025
Atomwise · bizjournals.com · Mar 18, 2025
Frequently asked questions
- What stage does OS Fund invest at?
- OS Fund invests at the Pre-Seed, Seed, Series A stages.
- What is OS Fund's typical check size?
- OS Fund typically writes checks of $1M – $2M.
- What sectors does OS Fund focus on?
- OS Fund focuses on AgTech, AI & Machine Learning, Biotech, Consumer, Crypto & Web3, Fintech, FoodTech, Healthtech, New Materials, SaaS.
- Where is OS Fund located?
- OS Fund is headquartered in Park Ridge, US.
- Does OS Fund lead rounds?
- OS Fund typically participates in rounds rather than leading them.
Media · Podcasts & interviews
featuring the teamBryan Johnson of OS Fund on building a company with soul
This Week in Startups · Bryan Johnson
Founder Bryan Johnson sold Braintree to build OS Fund & help humanity w/science
This Week in Startups · Bryan Johnson
BRYAN JOHNSON | BRAINTREE, OS FUND | STARTUP GRIND SILICON VALLEY
Startup Grind · Bryan Johnson
Bryan Johnson (Braintree & OS Fund) at Startup Grind Chicago
Startup Grind Local · Bryan Johnson
Co-investors · 3
IA Ventures is a venture capital firm that invests in early-stage software and frontier technology companies.
Andreessen Horowitz (a16z) is a venture capital firm founded in 2009 by Marc Andreessen and Ben Horowitz, known for pioneering the platform model with a large team of operators supporting founders across stages.
The General Partnership (thegp) is a venture firm that supports founders with hiring, product execution, and go-to-market help to close the execution gaps that can undermine growing companies.
Firms observed investing alongside OS Fund, from public investor directories. Shared companies are the overlap with OS Fund's recorded portfolio.
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