TSVC
Venture capitalActively deployingSilicon Valley · Pre-Seed–Series A · 25 people tracked
Also known as TSVC MANAGEMENT LLC
Investment thesis
TSVC is a Silicon Valley seed-stage venture firm founded in 2010 by serial entrepreneurs and engineers, focused on partnering early with technically ambitious founders tackling difficult challenges. Its portfolio spans more than 200 early-stage companies, including over 12 unicorns and public firms such as Zoom, Carta, and Ginkgo Bioworks. Today the firm concentrates on the next wave of innovation at the intersection of AI, robotics, advanced manufacturing, and energy systems. TSVC anticipates a 'Physical AI economy' in which intelligent machines, autonomous systems, and next-generation infrastructure transform the physical world, and it seeks founders aiming to build the defining companies of that future.
Source: firm website, verified Jul 29, 2026.
Team · 25 people
from the firm's website & public directories
What they invest in
from 55 of 84 portfolio companiesAI & Machine Learning ×22SaaS ×19Deep Tech ×13Enterprise Software ×13Hardware ×11Healthtech ×10Medical Devices ×9Biotech ×8
HQs:United States×33Canada×2China×2Singapore×1
Investments · 84 tracked
founders shown can be your intro path
Ginkgo Bioworks develops autonomous laboratory systems that automate manual benchwork in biotechnology R&D, enabling scientists to conduct experiments through natural language requests rather than manual lab work.
AI & Machine LearningBiotechDeep TechHealthtechBoston, US
Jason Kelly(Founder)inAustin Che(Founder)inTom Knight(Founder)inBarry Canton(Founder)inReshma Shetty(Founder)in
BoardReshma Sohoni
BiotechRedwood City, US
Herb Cross(Executive Officer)Jeet Mahal(Executive Officer, Director)Patrick Crutcher(Director)Thomas Wiggans(Director)Judith Shizuru(Director)Svetlana Lucas(Director)
Petal is developing an incisionless surgery platform using Millisecond Pulse Histotripsy, a form of focused therapeutic ultrasound that breaks down targeted diseased tissue without incisions, heat, or trauma.
Deep TechHealthtechMedical Devices
Prash Chopra(Founding CEO & Director)Bowen Jiang(Co-founder)Nicholas Theodore(Co-founder & Director)Rony Abovitz(Co-founding Advisor)
Petal Surgical develops an incisionless surgery platform using Millisecond Pulse Histotripsy, a form of focused therapeutic ultrasound that breaks down targeted tissue via "Acoustic Liquefaction" without cutting, heat, or trauma.
Deep TechHealthtechMedical Devices
Prash Chopra(Founding CEO & Director)Bowen Jiang(Co-founder)Nicholas Theodore(Co-founder & Director)Frederic H. Moll(Director)Rony Abovitz(Co-founding Advisor)
Santa Clara, US
Eugene Zhang(Director)Guan Wang(Director, Executive Officer, Promoter)Hao Du(Director, Executive Officer, Promoter)Tim Wang(Executive Officer, Promoter)
Board seatEugene Zhang· per SEC Form D · $8.2M raise · filed Mar 2024
Alpine Optoelectronics designs and manufactures high-speed optical transceivers, including 100G QSFP28 DWDM/xWDM and 800G QSFP-DD/OSFP LPO modules built on silicon photonics for data center and networking links over single-mode fiber.
Deep TechHardwareSemiconductors
Angle Health is an AI-enabled health insurance platform that serves employers and their employees by consolidating carrier, third-party administrator, and managing general underwriter functions into a single integrated experience.
AI & Machine LearningFintechHealthtechInsurTechSaaSSan Francisco, US
Atrius provides a cloud-based suite of applications and a unified data platform for the built environment, covering energy and sustainability tracking, indoor mapping and wayfinding, facilities and equipment health monitoring, and space and asset utilization.
Climate TechPropTechSaaS
Automat Solutions is a U.S.-based company that develops battery electrolytes and uses AI to accelerate materials discovery and formulation.
AI & Machine LearningEnergyNew MaterialsSan Leandro, US
Blueprint is a product team that was acquired by David's Bridal in August 2018 and focuses on delivering user experiences within the bridal industry.
ConsumerFintechMarketplacesSeattle, US
Elizabeth Ellingson(Executive Officer, Director)Nevin Shetty(Executive Officer, Director)j P Whaley(Director)
California Catalysts develops advanced materials and catalysts for hydrogen electrolysis using AI-driven discovery methods.
AI & Machine LearningCleantechEnergyNew MaterialsLos Angeles, US
Jim DiSanto(Co-founder, Board Director, Executive Consultant)
BoardNathan Lewis(Chief Scientific Advisor)
Carta is a cloud-based ERP platform for private capital markets that manages cap tables, equity administration, fund management, and valuations for startups, private companies, and venture funds globally.
Enterprise SoftwareFintechSaaS<UNKNOWN>
Henry Ward(Co-founder)Manu Kumar(Co-founder)Charly Kevers(Chief Financial Officer)Jeff Perry(Chief Revenue Officer)Nick Avery(Chief People Officer)Nicole Baer(Chief Marketing Officer)
Celldom builds a live single-cell biology platform that uses microwell arrays in standard culture plate format, automated imaging, incubation, and real-time analysis to measure morphology, phenotypes, secreted proteins, gene expression, and cell-cell interactions across more than 100,000 cells per plate.
BiotechDeep TechHardware
Platform helping IT, security and procurement teams manage and renew SaaS apps
d-Matrix develops AI compute hardware and platforms optimized for generative AI inference, designed to be faster, more energy-efficient, and more accessible than existing solutions.
AI & Machine LearningHardwareSemiconductors
Element Biosciences develops biological analysis platforms and DNA sequencing tools for scientists and research institutions.
BiotechDeep TechHardwareMedical Devices
New York, US
Atish Davda(Executive Officer, Director)Philip Haslett(Executive Officer, Director)Shriram Bhashyam(Executive Officer, Director)
Exa is an AI-powered search API that retrieves high-quality information from the web in real-time, designed for AI agents, developers, and applications that require precise natural-language search capabilities.
AI & Machine LearningData & InfrastructureDeveloper ToolsEnterprise SoftwareSan Francisco, US
William Bryk(co-founder/CEO)inJeffrey Wang(Founder)inWalden Yan(Co-Founder)
Gaatu is an ecommerce company that operates several consumer product brands, including ViPEK garment racks, Broview storage solutions, MaxAuto lawnmower tires, and PARTSam decorative vehicle lighting.
ConsumerE-commerceLogistics & Supply ChainMilpitas, US
Yubin Pu(Executive Officer, Director)Changsong Zhu(Director)Yuqing Zhang(Director)
Iterable provides customer communication and engagement software that enables brands to create targeted messaging experiences across email, SMS, push, and other channels.
AI & Machine LearningEnterprise SoftwareMarketing TechSaaSSan Francisco, US
Andrew Boni(Co-founder, CEO (2021-2025))inHaoran Zhu(Executive Officer, Director)Sabri Murat Bicer(Director)
Juzibot develops AI agents for enterprise workflows, enabling companies to automate tasks across departments from management to frontline operations through conversational AI integrated with workplace communication tools.
AI & Machine LearningDeveloper ToolsEnterprise SoftwareSaaSBeijing, CN
Kinet-IC designs analog and power management integrated circuits, including overvoltage and surge protection, USB data line protection, EMI/ESD suppression, load switches and eFuses, DC-DC converters, PoE controllers, LED drivers, and wireless power receivers.
Deep TechHardwareSemiconductors
Lex Machina is a legal analytics platform that converts court documents and legal data into structured insights for law firms and legal professionals.
AI & Machine LearningData & InfrastructureLegalTech
Lumotive develops Light Control Metasurface (LCM) chips that steer and shape light without moving parts for optical beamforming.
Deep TechHardwareSemiconductors
Medrio is an electronic data capture (EDC) platform designed for clinical trial teams at life sciences sponsors and contract research organizations.
Digital HealthMedical DevicesSaaS<UNKNOWN>, US
Michael Novotny(Executive Officer, Director)Richard Scheller(Director)Doug Engfer(Director)Dave Lipscomb(Director)
BoardRyan Drant(Director)Bradley Sloan(Director)
Multibeam develops a multicolumn electron-beam lithography platform for semiconductor manufacturing.
Deep TechHardwareSemiconductorsSunnyvale, US
Social networks for millions of people living with chronic conditions
San Francisco, US
Eric Peacock(Executive Officer, Director)Anne Raimondi(Director)Robin Murray(Director)Gary Dillabough(Director)
Oculi builds a Sensing and Processing Unit (SPU) that integrates AI vision at the pixel level, running vision processing on-chip to transmit only the information needed to detect what is in a scene without cloud dependency.
AI & Machine LearningHardwareSemiconductors
Opentrons develops laboratory robots that automate scientific research tasks for scientists and research institutions.
AI & Machine LearningBiotechHardwareHealthtechMedical DevicesRoboticsNew York City, US
Nicholas Wagner(Founder)inWill Canine(Founder/CPO)inChiu Chau(Founder)inJuan Franck(Director)Leslie Mitchell(Director)Myrtle Potter(Director)
Perceptive applies AI and robotics technology to dental practice, helping dentists increase patient capacity.
AI & Machine LearningHealthtechMedical DevicesRoboticsBoston, US
Chris Ciriello(Founder)inScott Phillips(Founder)inPhil Getto(CTO)Alex Furleigh(Chief of Staff)
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.
Frequently asked questions
- What stage does TSVC invest at?
- TSVC invests at the Pre-Seed, Seed, Series A stages.
- What is TSVC's typical check size?
- TSVC typically writes checks of $1M.
- What sectors does TSVC focus on?
- TSVC focuses on Advanced Manufacturing, AI & Machine Learning, Crypto & Web3, Deep Tech, Energy, Robotics.
- Where is TSVC located?
- TSVC is headquartered in Silicon Valley, US.
- Does TSVC lead rounds?
- Yes, TSVC leads investment rounds.
Media · Podcasts & interviews
featuring the teamEugene Zhang, Founding Partner at TSVC: What's the Deal with Venture Capital and Tech Right Now?
The Blind Ambition Podcast with Jack Kelly · Eugene Zhang
Eugene Zhang - Founder and CEO at TSVC explains success in leadership
Single Focus Talent · Eugene Zhang
Meet the Manager Eugene Zhang Founding Partner at TSVC
iConnections · Eugene Zhang
Co-investors · 100
Andreessen Horowitz's Strategic Partnerships page describes collaborations that connect its portfolio companies with established institutions to help scale and deploy their technology.
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Ulu Ventures is a seed-stage venture capital firm focused on finding and funding early-stage founder teams, emphasizing diversity and data-driven investment decisions.
MaC Venture Capital is an early-stage venture capital firm that partners closely with founders, offering hands-on support and strategic involvement beyond capital.
Foothill Ventures is a technology-focused venture fund based in Los Altos, California, run by a team with founder and operator backgrounds. It makes early-stage investments in frontier technology, particularly infrastructure and AI applications.
Khosla Ventures is a venture capital firm known for backing bold, contrarian bets in world-class teams that can reshape entire industries.
Techstars is a startup accelerator and early-stage investor that funds ambitious founders and provides capital, mentorship, and access to a global network of investors, operators, and corporate partners.
K9 Ventures is a venture capital firm that relies on referrals from its trusted network and invests based on relationships.
Fusion Fund is an early-stage venture capital firm backing startups with technical or data advantages in healthcare, enterprise AI, and industrial technology.
Merus Capital is a venture capital firm that backs ambitious teams building industry-defining technology platforms.
AMINO Capital is a global venture capital firm based in Palo Alto that invests around the theme of data moat and network effects, focusing on big data, machine learning, and exceptional products.
Brighter Capital is a family angel fund founded by a former Facebook engineer that invests in early-stage startups, making 10-20 direct investments per year.
▶88 more co-investors
GV (Google Ventures)Lightspeed Venture PartnersLong Journey VenturesNotable CapitalDCVC (Data Collective)Streamlined VenturesBling CapitalBullpen CapitalDCM VenturesAngelPadSpider CapitalM12 (Microsoft's Venture Fund)137 VenturesWndrCoRivet VenturesNewfund CapitalSony Ventures CorporationTunitas VenturesPruVen Capital PartnersOakseed VenturesSequoia CapitalFounders FundCraft VenturesAlumni VenturesRedpoint VenturesInsight PartnersSV AngelUnknown VenturesFoundation CapitalCoatue ManagementKrakenDST GlobalGreat Oaks Venture CapitalPlug and Play VenturesEniac VenturesQuiet CapitalSOSVSusa VenturesUpHonest CapitalSciFi VCKapor CapitalAmplify PartnersPractical Venture CapitalTrajectory VenturesLowercase CapitalOperator LPAltaIR Capital500 StartupsPareto HoldingsAntlerLOI VentureZetta Venture PartnersHeavybitLocus VenturesPrefix CapitalOyster VenturesScrum VenturesAmasiaRubicon Venture CapitalThomvest VenturesRally Ventures Management, LlcThink+ Ventures Management, LlcScout VenturesAI FundHC9 VenturesBINARY CAPITALEngineering CapitalIlluminate VenturesPortage VenturesStrata Capital PartnersBand of AngelsElefundXSeed CapitalFirsthandVCGSR VenturesBoosted CommerceFeenix Venture Partners LLCInnovation WorksRiverfront Ventures, LLCArgonautic VenturesHorizon 3 Venture StudioTensility Venture PartnersZhenFundHarmonix Music SystemsCabra VCMotus Ventures, LlcVine Street VenturesLuminate
Firms observed investing alongside TSVC, from public investor directories. Shared companies are the overlap with TSVC's recorded portfolio.
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