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Tango Therapeutics

NASDAQ: TNGX

Boston, US · Founded 2020 · Delaware corporation · 4 known investors

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Tango Therapeutics develops genetically targeted medicines using synthetic lethality principles to treat specific tumors. The company focuses on expanding access to precision cancer therapies for patients.

Biotech

Founders & leadership

Tango Therapeutics was founded in 2020 by Alan Huang.

AHAlan Huang
Alan HuangFounderHe has spent approximately a decade in CAR-T cell therapy drug development, with experience in manufacturing, regulatory compliance, project management, and team leadership.
ACAdam Crystal
Adam CrystalPresident, Research and DevelopmentAdam Crystal is an MD-PhD medical oncologist and biotech executive with drug discovery and development experience in pharma and biotech, specializing in small-molecule oncology therapeutics and novel target identification. He is an Executive Officer at Tango Therapeutics.
DBDaniella Beckman
Daniella BeckmanCFO
DB
Douglas BarryNamed on SEC filing
AD
Aaron DavisNamed on SEC filing

Board

BWBarbara Weber
Barbara WeberChairperson of the BoardVenture Partner at Third Rock Ventures
KPKanishka Pothula
Kanishka PothulaBoard directorManaging Partner at Nextech Invest
LA
Lesley Ann CalhounBoard Member, Audit Committee ChairExecutive Vice President, Chief Operating Officer & Chief Financial Officer at Aligos Therapeutics
ABAlexis Borisy
Alexis BorisyBoard directorChairman at Nextech Invest
RHReid Huber
Reid HuberDirector2019–2023Partner at Third Rock Ventures
JK
John KetchumBoard director
MP
Malte PetersBoard director

Investors · 4

Nextech Investlisted by Nextech InvestZurich · $648K – $3.2Mvia Kanishka Pothula · board

How we know: board seat on SEC Form D · open dataset · 5k.vc investor directory · Not right? Tell us

NSG Ventureslisted by NSG VenturesSingapore
Third Rock Ventureslisted by Third Rock VenturesBoston · $100K – $5M

How we know: Third Rock Ventures's portfolio page · board seat on SEC Form D · open dataset · 5k.vc investor directory · Not right? Tell us

Reported raises · per SEC filings

Form D private placements

$95M disclosed across 2 rounds · 2023–2025

▶$15MraisedOct 2025 · 1 investors · Pharmaceuticals
Rule 506(b)
Officers, directors & promoters on the filing
  • John KetchumDirector
  • Barbara WeberExecutive Officer, Director
  • Malte PetersDirector
  • Kanishka PothulaDirector
  • Lesley Ann CalhounDirector
  • Mace RothenbergDirector
  • Alexis BorisyDirector
  • Adam CrystalExecutive Officer
  • Daniella BeckmanExecutive Officer
Offering amount
$15M
Amount sold
$15M
First sale
Oct 2025
Incorporated
Corporation, Delaware
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$80MraisedAug 2023 · 17 investors · Pharmaceuticals
Rule 506(b)
Officers, directors & promoters on the filing
  • Lesley Ann CalhounDirector
  • Adam CrystalExecutive Officer
  • Douglas BarryExecutive Officer
  • Mace RothenbergDirector
  • Alexis BorisyDirector
  • Alan HuangExecutive Officer
  • Barbara WeberExecutive Officer, Director
  • Daniella BeckmanExecutive Officer
  • Malte PetersDirector
  • Reid HuberDirector
  • Aaron DavisDirector
Offering amount
$80M
Amount sold
$80M
First sale
Aug 2023
Incorporated
Corporation, Delaware, 2020
Federal exemptions
06b
Full filing on SEC EDGAR ↗

Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.

Founder mafia

3 people who came through Tango Therapeutics went on to found or lead other companies.

Reid HuberDirectorFounded MOMA Therapeutics +2Alexis BorisyChairman Of The BoardFounded Foundation Medicine +2Fang LiDirector of Translational and Computational BiologyFounded Allorion Therapeutics

Related companies · 3

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Frequently asked questions

What does Tango Therapeutics do?
Tango Therapeutics develops genetically targeted medicines using synthetic lethality principles to treat specific tumors. The company focuses on expanding access to precision cancer therapies for patients.
Who founded Tango Therapeutics?
Tango Therapeutics was founded by Alan Huang in 2020.
Who are Tango Therapeutics's investors?
Tango Therapeutics's investors include Foresite Capital, Nextech Invest, NSG Ventures, Third Rock Ventures.
How much funding has Tango Therapeutics raised?
Tango Therapeutics has disclosed $95M raised across 2 rounds.
Where is Tango Therapeutics headquartered?
Tango Therapeutics is headquartered in Boston, US.