Fundraising Fox

Paragon Biosciences LLC

Venture studio

Chicago Β· Seed–Series A Β· 1 people tracked

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Investment thesis

Paragon Biosciences operates as a company creator, combining best practices of established organizations with a portfolio approach to advanced science. It launches new companies built around cutting-edge scientific breakthroughs, supporting them with in-house capabilities across clinical development, regulatory affairs, manufacturing, and commercialization. Its focus centers on life sciences and biotechnology, aiming to translate emerging science into commercial-stage businesses.

Source: firm website, verified Aug 3, 2026.

Stage
Seed–Series A
HQ
Chicago, Illinois, US
Instruments
Equity
Founded
2010
Tracked investments
6

Team Β· 1 people

from the firm's website

What they invest in

from 6 of 6 portfolio companies

Biotech Γ—6Medical Devices Γ—4Deep Tech Γ—3Healthtech Γ—2AI & Machine Learning Γ—1Digital Health Γ—1

HQs:United StatesΓ—3

Investments Β· 6 tracked

founders shown can be your intro path

By year:2023 Β· 12022 Β· 12 dated

Harmony Biosciencesharmonybiosciences.comin𝕏NASDAQ: HRMY

Harmony Biosciences develops innovative therapeutic treatments focused on rare neurological diseases.

BiotechHealthtechMedical DevicesNorthbrook, US

Jeffrey Aronin(Director)inJeffrey M. Dayno, M.D.(President and Chief Executive Officer)inPatrick Morris(Secretary and Treasurer)inRobert Repella(Director and Chief Executive Officer)Darien Parhad(Chief Financial Officer)

BoardAaron Royston(Director)in

Co-investorsAisling CapitalValor Equity PartnersvenBio PartnersVivo Capital

Circ Biosciencescircbiosciences.comβœ“ verified

CiRC Biosciences develops cellular reprogramming therapies that convert fibroblasts directly into specific neurons and cell types lost in degenerative eye and brain diseases.

BiotechDeep TechMedical Devices

Co-investorsPortal Innovations

Emalexemalex.cominπ•βœ“ verified

Emalex Biosciences is a clinical-stage biopharmaceutical company developing treatments for central nervous system disorders, with a lead investigational asset, ecopipam, a selective dopamine D1 receptor antagonist for pediatric Tourette syndrome.

BiotechDigital Health

Co-investorsValor Equity Partners

Emalex Biosciencesemalexbiosciences.cominπ•βœ“ verified

Emalex Biosciences is a clinical-stage biopharmaceutical company developing treatments for central nervous system disorders, including ecopipam, an investigational dopamine D1 receptor antagonist for pediatric Tourette syndrome.

BiotechMedical Devices

Co-investorsBain Capital Life Sciences

Evozyneevozyne.cominSep 2023 Β· $81Mβœ“ verified

Evozyne designs and builds engineered protein therapeutics using an AI-native platform, focusing on treatments for immune-mediated diseases.

AI & Machine LearningBiotechDeep TechHealthtechChicago, US

Aris Theologis(Executive Officer, Director)inDarien Parhad(Executive Officer)Patrick J. Morris(Executive Officer, Director)Marc Yoskowitz(CEO)inRama Ranganathan(Executive Officer, Director)

BoardJeffrey S. Aronin(Director)

Co-investorsOrbiMedFidelity InvestmentsNVenturesNVIDIAValor Equity Partners

Castle Creek Biosciencescastlecreekbio.comin𝕏May 2022 Β· $112.8M

Castle Creek Biosciences develops re-dosable gene therapies for genetic diseases, with a lead candidate (D-Fi) in registrational clinical trials for dystrophic epidermolysis bullosa.

BiotechDeep TechMedical DevicesExton, US

Matthew Gantz(President and Chief Executive Officer)inDavid ChuinMichael TownsleyChristopher J. LarsoninRhea WilliamsinJude Sullivan(Executive Officer)

Co-investorsValor Equity PartnersFidelity InvestmentsHorizon

Exits Β· 1

IPOs and acquisitions across the tracked portfolio

Harmony BiosciencesNASDAQ: HRMY

Portfolio news

latest coverage across their companies

Frequently asked questions

How many investments has Paragon Biosciences LLC made?
Paragon Biosciences LLC has 5 tracked investments.
What stage does Paragon Biosciences LLC invest at?
Paragon Biosciences LLC invests at the Seed, Series A stages.
What sectors does Paragon Biosciences LLC focus on?
Paragon Biosciences LLC focuses on Biotech, Healthtech, Longevity.
Where is Paragon Biosciences LLC located?
Paragon Biosciences LLC is headquartered in Chicago, US.
Who does Paragon Biosciences LLC co-invest with?
Paragon Biosciences LLC most often shares deals with Valor Equity Partners, Aisling Capital, OrbiMed, among 6 tracked co-investors.

Media Β· Podcasts & interviews

from their channel

Jeffrey Dayno, MD, Highlights Harmony Biosciences' Commitment to Patients, Passion and Purpose

Paragon Biosciences

How Paragon is Leading the Bio-Revolution

Paragon Biosciences

CiRC Biosciences--Advancing Vision Restoration Cell Therapy

Paragon Biosciences

Jeff Aronin Discusses the Acceleration of Life Science Innovation at Paragon Biosciences

Paragon Biosciences

Images

Paragon Biosciences LLC photo

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