Paragon Biosciences LLC
Venture studioChicago · Seed–Series A · 1 people tracked
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Investment thesis
Paragon Biosciences operates as a company creator, combining best practices of established organizations with a portfolio approach to advanced science. It launches new companies built around cutting-edge scientific breakthroughs, supporting them with in-house capabilities across clinical development, regulatory affairs, manufacturing, and commercialization. Its focus centers on life sciences and biotechnology, aiming to translate emerging science into commercial-stage businesses.
Source: firm website, verified Oct 3, 2026.
Team · 1 people
from the firm's websiteWhat they invest in
from 6 of 6 portfolio companiesBiotech ×6Medical Devices ×4Deep Tech ×3Healthtech ×2AI & Machine Learning ×1Digital Health ×1
HQs:United States×4
Investments · 6 tracked
founders shown can be your intro pathBy year:2023 · 12022 · 22021 · 14 dated
Harmony Biosciences develops innovative therapeutic treatments focused on rare neurological diseases.
BiotechHealthtechMedical DevicesNorthbrook, US
Jeffrey Aronin(Director)inJeffrey M. Dayno, M.D.(President and Chief Executive Officer)inPatrick Morris(Secretary and Treasurer)inRobert Repella(Director and Chief Executive Officer)Darien Parhad(Chief Financial Officer)
BoardAaron Royston(Director)in
Co-investorsAisling CapitalHBM Healthcare InvestmentsHBM PartnersPivotal Life SciencesValor Equity PartnersvenBio Partners+3 more
CiRC Biosciences develops cellular reprogramming therapies that convert fibroblasts directly into specific neurons and cell types lost in degenerative eye and brain diseases.
BiotechDeep TechMedical DevicesChicago, US
Darien Parhad(Executive Officer)Patrick Morris(Executive Officer, Director)Sai Chavala(Director)
BoardTimothy Cunniff(Director)Antonio Gracias(Director)inJeffrey Aronin(Director)
Co-investorsPortal InnovationsValor Equity Partners
Emalex Biosciences is a clinical-stage biopharmaceutical company developing treatments for central nervous system disorders, with a lead investigational asset, ecopipam, a selective dopamine D1 receptor antagonist for pediatric Tourette syndrome.
BiotechDigital Health
Co-investorsValor Equity PartnersBain Capital Life SciencesFidelity Investments
Emalex Biosciences is a clinical-stage biopharmaceutical company developing treatments for central nervous system disorders, including ecopipam, an investigational dopamine D1 receptor antagonist for pediatric Tourette syndrome.
BiotechMedical Devices
Jeff Aronin(Founder)
Co-investorsBain Capital Life SciencesFidelity InvestmentsValor Equity Partners
Evozyne designs and builds engineered protein therapeutics using an AI-native platform, focusing on treatments for immune-mediated diseases.
AI & Machine LearningBiotechDeep TechHealthtechChicago, US
Aris Theologis(Executive Officer, Director)inDarien Parhad(Executive Officer)Patrick J. Morris(Executive Officer, Director)Marc Yoskowitz(CEO)inRama Ranganathan(Founder)Andrew Ferguson(Founder)
Co-investorsIn-Q-TelNVIDIAOrbiMedValor Equity PartnersFidelity InvestmentsNVentures
Castle Creek Biosciences develops re-dosable gene therapies for genetic diseases, with a lead candidate (D-Fi) in registrational clinical trials for dystrophic epidermolysis bullosa.
BiotechDeep TechMedical DevicesExton, US
Matthew Gantz(President and Chief Executive Officer)inDavid ChuinMichael TownsleyChristopher J. LarsoninRhea WilliamsinJude Sullivan(Executive Officer)
Co-investorsValor Equity PartnersFidelity InvestmentsHorizon
Exits · 1
1 IPOsHarmony BiosciencesNASDAQ: HRMY
Frequently asked questions
- How many investments has Paragon Biosciences LLC made?
- Paragon Biosciences LLC has 6 tracked investments, 1 of which have exited.
- What stage does Paragon Biosciences LLC invest at?
- Paragon Biosciences LLC invests at the Seed, Series A stages.
- What sectors does Paragon Biosciences LLC focus on?
- Paragon Biosciences LLC focuses on AI & Machine Learning, Biotech, Healthtech, Longevity.
- Where is Paragon Biosciences LLC located?
- Paragon Biosciences LLC is headquartered in Chicago, US.
- Who does Paragon Biosciences LLC co-invest with?
- Paragon Biosciences LLC most often shares deals with Valor Equity Partners, Aisling Capital, In-Q-Tel, among 11 tracked co-investors.
Media · Podcasts & interviews
from their channelJeffrey Dayno, MD, Highlights Harmony Biosciences' Commitment to Patients, Passion and Purpose
Paragon Biosciences
How Paragon is Leading the Bio-Revolution
Paragon Biosciences
CiRC Biosciences--Advancing Vision Restoration Cell Therapy
Paragon Biosciences
Jeff Aronin Discusses the Acceleration of Life Science Innovation at Paragon Biosciences
Paragon Biosciences
Images
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