Fundraising Fox
Montreal · Pre-Seed–Series B · 16 people tracked
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Investment thesis
Amplitude Ventures positions itself as company builders in precision medicine, backing and growing biotech and health science companies that improve patient outcomes. The firm invests across the lifecycle from ideation to patient care, partnering closely with founders, scientists, and entrepreneurs. Emphasizing values of excellence, transparency, and integrity, the team combines investing with hands-on operational and scientific expertise, often taking board roles and supporting portfolio companies through financings, strategy, talent recruitment, and investor introductions. It also runs the Amplitude Fellowship, a summer program bringing together Canada's health-focused PhD candidates, post docs, and MDs to explore biotech concepts and form new health science companies.
Source: firm website, verified Sep 27, 2026.
Team · 16 people
from the firm's website & public directories
Founder mafia
3 people who came through Amplitude Venture Capital went on to found or lead other companies.
What they invest in
from 12 of 22 portfolio companiesBiotech ×10Healthtech ×7Medical Devices ×6Deep Tech ×4AI & Machine Learning ×2Digital Health ×2Fintech ×1Marketplaces ×1
HQs:United States×6Canada×2
Investments · 22 tracked
founders shown can be your intro pathBy year:2026 · 12024 · 22023 · 32022 · 22021 · 22019 · 12018 · 12017 · 113 dated
Zymeworks is a biotechnology company that develops novel therapeutics for patients with difficult-to-treat diseases using its proprietary drug-development platforms and in-house R&D.
BiotechHealthtechVancouver, US
ALI TEHRANI(Executive Officer, Director)inGORDON NG(Executive Officer)NEIL KLOMPAS(Executive Officer)inSURJIT DIXIT(Executive Officer)inDAVID TUCKER(Executive Officer)Paul Moore(Chief Scientific Officer)in
Co-investorsBrace PharmaCTI Life Sciences Fund L.P.HBM Healthcare InvestmentsLumira VenturesNextech InvestWUTIF Capital
Milestone Pharmaceuticals is a life sciences company that develops therapies for patients with cardiovascular and other diseases.
BiotechDigital HealthHealthtechMedical DevicesMontreal, US
Ela Borenstein(Director)Francis Plat(Executive Officer)Yves Rosconi(Director)Scott Weiner(Director)Martin Maguire(Executive Officer)Philippe Douville(Executive Officer, Director)
Board seatDion Madsen· per SEC Form D · $6.9M raise · filed Jul 2017
Co-investorsPappas CapitalDomain AssociatesForbionRTW Investments L.P.
Combines single-cell RNA analysis technology from the Broad Institute with AI/ML models and large-scale clinical sample collection for novel drug discovery and precision medicine.
HealthtechCambridge, US
Tariq Kassum(Executive Officer, Director)inMichael Boretti(Executive Officer)inChristoph Lengauer(Executive Officer, Director)in
Co-investorsCatalio Capital Management, LPFast Track InitiativeGV (Google Ventures)AlexandriaCasdin CapitalThird Rock Ventures
Congruence is a drug discovery company that applies protein dynamics, biophysics, machine learning, and computational chemistry to model proteins in their full dynamic state and predict disease correction in silico.
AI & Machine LearningBiotechDeep Tech
Clarissa Desjardins(Founder)in
Co-investorsOrbiMedAlexandriaDIMENSIONAngelini VenturesBDC Thrive Venture Fund for WomenLumira Ventures+1 more
Fluid Biomed develops a bioresorbable polymer-based stent designed to treat brain aneurysms by diverting blood flow and reducing risk of stroke.
BiotechDeep TechHealthtechMedical DevicesCalgary, CA
Dr. John H. Wong(Co-founder & Chief Executive Officer)Dr. Alim P. Mitha(Co-founder, President & Chief Technology Officer)
Co-investorsAccelerate FundLifeArc VenturesShangBay Capital LLCSymbiotic VenturesThin Air LabsUCeed Funds+1 more
Gandeeva Therapeutics uses AI, machine learning, and atomic-resolution cryo-EM imaging to map druggable protein interactions and design molecular glues that bind at specific protein interfaces.
AI & Machine LearningBiotechDeep TechDigital Health
Sriram Subramaniam(Founder)in
Co-investorsAir Street CapitalLux CapitalObvious VenturesAmgen VenturesLeaps by Bayer
Mediartx develops novel therapies for patients with fibrotic diseases.
BiotechMedical DevicesBoston, US
Rahul Ballal, PhD(CEO)Paul Yaworsky, PhD(CSO)inRahul Ballal(Executive Officer, Director)inBrian Hubbard(Director)Stacey Brenner(Executive Officer)David de Graaf(Director)
Co-investorsAgent CapitalGimvLongwood FundMission BiocapitalNovartis Venture FundOno Venture Investment, Inc.+5 more
Nomic offers an end-to-end protein profiling service built on its nELISA technology, quantifying up to 1000 informative proteins with absolute quantification for research studies.
BiotechDeep TechHealthtechMedical DevicesMontreal, CA
Milad Dagher(Founder)inJeff Munzar(Founder)inElisha Krauss(Operations Manager)Ani Muradyan(Recruiter)
Co-investorsAvant BioFirst Star VenturesFront Row VenturesRaptor GroupY Combinator2048 Ventures+9 more
Prilenia is a biotechnology company developing treatments for neurodegenerative diseases, including Huntington's disease and amyotrophic lateral sclerosis (ALS).
BiotechHealthtechMedical Devices
Co-investorsALS Investment FundSV Health InvestorsForbion
Radiant Biotherapeutics develops a platform of therapeutic molecules called Multabodies that engage multiple disease targets simultaneously within a single engineered protein to treat cancer and infectious diseases.
BiotechMedical Devices
Arthur Fratamico(Executive Officer, Promoter)Deborah Geraghty, Ph.D.(President and Chief Executive Officer)
Co-investorsFACIT (Fight Against Cancer Innovation Trust)Toronto Innovation Acceleration PartnersBill & Melinda Gates Foundation
Reverb Therapeutics develops immunotherapies built on its Amplify•R platform, which modulates the body's natural immune system using targeted molecules such as IL-15-directed compounds.
BiotechHealthtech
Co-investorsFinchley Healthcare VenturesInBC Investment Corp.Thin Air LabsKdT Ventures
Valence provides a trading terminal that unifies execution across prediction markets including Kalshi and Polymarket, routing orders intelligently across multiple venues to achieve optimal pricing.
FintechMarketplacesSan Francisco, US
Neo Wang(Founder)inDaniel Kasabov-Nouvion(Founder)inArthur Zhou(Founder)inParker Mitchell(Founder)
Co-investorsY CombinatorAlpha PartnersANIMO VenturesBessemer Venture PartnersDifferential VenturesFirstMark Capital+2 more
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
Abdera TherapeuticsAbility biologicsCelciusEvolved TherapeuticsEvommuneGiiant PharmaImagiaTentarix BiotherapeuticsThryv Therapeutics
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.
Exits · 2
1 IPOs · 1 acquisitionsZymeworksNASDAQ: ZYMECelsius Therapeuticsacq. by AbbVie
Portfolio news
latest coverage across their companiesValence · ycombinator.com · Mar 5, 2026
Frequently asked questions
- How many investments has Amplitude Venture Capital made?
- Amplitude Venture Capital has 22 tracked investments, 2 of which have exited, including 2 dated in the last 24 months.
- What stage does Amplitude Venture Capital invest at?
- Amplitude Venture Capital invests at the Pre-Seed, Seed, Series A, Series B stages.
- What sectors does Amplitude Venture Capital focus on?
- Amplitude Venture Capital focuses on AI & Machine Learning, Biotech, Digital Health, Healthtech, Medical Devices.
- Where is Amplitude Venture Capital located?
- Amplitude Venture Capital is headquartered in Montreal, CA.
- Does Amplitude Venture Capital lead rounds?
- Amplitude Venture Capital typically participates in rounds rather than leading them.
- Who does Amplitude Venture Capital co-invest with?
- Amplitude Venture Capital most often shares deals with Avant Bio, First Star Ventures, InBC Investment Corp., among 8 tracked co-investors.
Images
Co-investors · 9
ShangBay Capital is a venture capital firm that invests in founders building disruptive companies addressing high, unmet clinical needs with novel ideas.
OrbiMed is a healthcare-focused investment firm providing tailored financing solutions and global resources to build world-class healthcare companies across biopharmaceuticals, medical devices, digital health, diagnostics, and healthcare services.
Dimension is a multistage investment firm that partners with companies working at the intersection of science and compute.
Versant Ventures operates in-house Discovery Engines staffed by multidisciplinary scientists in dedicated laboratory facilities to help launch new biotechnology companies alongside academic founders.
Domain Associates is a venture capital firm founded in 1985 that invests in life sciences companies. The firm operates as a limited liability company.
Venrock is a venture capital firm investing across technology and healthcare, backing companies in fintech, developer infrastructure, life sciences, therapeutics, semiconductors, and consumer products.
This is the Analysis and Research section of BDC (Business Development Bank of Canada), publishing studies, surveys and reports on issues affecting Canadian small and medium-sized businesses.
Samsara BioCapital is a life-sciences investment firm backing companies developing transformative therapeutics for patients.
Pappas Capital is a life science-focused investment firm that invests in and helps build companies developing next-generation life science products and technologies.
Firms observed investing alongside Amplitude Venture Capital, from public investor directories. Shared companies are the overlap with Amplitude Venture Capital's recorded portfolio.
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