Fundraising FoxCLI Ventures
Venture capitalPalo Alto · Seed–Late Stage · 3 people tracked
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Investment thesis
CLI Ventures backs strong founders building toward the future, supporting companies across early to late stages of growth. Its selected portfolio spans technology-driven real estate, gene-editing biopharmaceuticals, and genomic cancer diagnostics, reflecting a broad interest in transformative, high-growth businesses that can reach public-market or acquisition outcomes.
Source: firm website, verified Oct 2, 2026.
Team · 3 people
from public directoriesWhat they invest in
from 16 of 22 portfolio companiesBiotech ×7Healthtech ×6Medical Devices ×5Deep Tech ×4AI & Machine Learning ×2Data & Infrastructure ×2Digital Health ×2PropTech ×2
HQs:United States×13Switzerland×1Vietnam×1
Investments · 22 tracked
founders shown can be your intro path
Compass is a real estate brokerage that uses technology to help consumers find homes.
B2B MarketplacesEnterprise SoftwareMarketplacesPropTechSaaSManhattan, US
Robert Reffkin(Founder & CEO)inOri Allon(Founder & Chief Strategist)Brad Serwin(Executive Officer)Kalani Reelitz(Executive Officer)Ethan Glass(Executive Officer)inScott Wahlers(Executive Officer)
Co-investors.406 VenturesAdvance Venture PartnersAlpaca VCAlumni VenturesAtomicoCorigin Ventures+9 more
Guardant Health develops blood-based testing (liquid biopsy) for cancer detection and monitoring across all stages of the disease.
BiotechDigital HealthHealthtechMedical DevicesRedwood City, US
AmirAli Talasaz(Executive Officer, Director)inHelmy Eltoukhy(Executive Officer, Director)inMichael Wiley(Executive Officer)inMichael Bell(Chief Financial Officer)Darya Chudova(Chief Technology Officer)inCraig Eagle(Chief Medical Officer)in
Co-investors8VCAUTHENTIC VENTURESCota CapitalFelicis VenturesKhosla VenturesKnockout Capital+9 more
Synlogic develops synthetic biology-based biotherapeutics that use engineered living organisms to treat diseases.
BiotechDeep TechMedical DevicesCambridge, US
Bharatt Chowrira(Executive Officer)inMichael Sheahan(Executive Officer)Jose Carlos Gutierrez-Ramos(Executive Officer, Director)inPaul Miller(Executive Officer)inAoife Brennan(Executive Officer)inTodd Shegog(Executive Officer)in
Co-investorsAtlas VentureNew Enterprise Associates (NEA)NSG VenturesPfizer Venture InvestmentsSofinnova VenturesSolasta Ventures+1 more
Arthena operates a financial fund that enables high-net-worth individuals to invest in art by using statistical models trained on auction data to identify and purchase artworks expected to appreciate with low correlation to traditional asset classes.
FintechNew York City, US
Madelaine D'Angelo(Founder/CEO)inMichael DAngelo(Co-Founder & CTO)in
Co-investorsClick VenturesFirstrock CapitalY Combinator1984 Ventures Management, Llc2020 VenturesAgrolimen Ventures+9 more
Civil Maps develops artificial intelligence for autonomous vehicle perception, creating continental-scale HD 3D maps and centimeter-level localization systems.
AI & Machine LearningDeep TechMobility & TransportationSilicon Valley, US
Co-investorsElev8.vcReshapeScrum VenturesTSVCAME Cloud VenturesMotus Ventures, Llc+1 more
CRISPR Therapeutics is a biotechnology company developing gene-based medicines using CRISPR/Cas9 gene-editing technology.
BiotechDeep TechHealthtechZug, CH
Emmanuelle Charpentier(Co-founder)Samarth Kulkarni(Chief Executive Officer and Chairman of the Board)inJames R. Kasinger(General Counsel and Secretary)inStephen Kennedy(Head of Technical Operations)inMegan Wherry Menner(Head of Human Resources)inNaimish Patel(Chief Medical Officer)in
Co-investorsAvoro Capital AdvisorsNew Enterprise Associates (NEA)AbingworthVersant Ventures
CStorePro provides cloud-based back-office software for convenience store operators.
Cloud ComputingData & Infrastructure
Arif Momin(Founder)in
Co-investors500 GlobalForefront VentureLaunchCapitalSandalphon CapitalSilicon Badia
Xoilac TV is a Vietnamese website for streaming live football matches with free Vietnamese-language commentary, covering leagues such as the Premier League, La Liga, Serie A, Bundesliga, V-League and World Cup.
ConsumerMedia & EntertainmentSports TechĐà Nẵng, VN
Co-investorsZillionizeLowercase CapitalMenlo VenturesQualcomm Ventures
Flirtey operates a drone delivery network that transports goods directly to customers for last-mile logistics.
Advanced ManufacturingRoboticsBlountville, US
Matthew Sweeny(Founder/CEO)in
Co-investorsY CombinatorACE & CompanyAmasiaBessemer Venture PartnersDHVCElysium Venture Capital+13 more
Genalyte develops Merlin, a real-time diagnostic system that performs laboratory testing directly in clinical settings and integrates results with electronic health records.
Digital HealthHardwareHealthtechMedical DevicesSan Diego, US
Cary Gunn(Co-founder and Chief Technical Officer)in
Co-investorsBioBritBoutique Venture PartnersClaremont Creek VenturesFusionX VenturesHBM Healthcare InvestmentsHBM Partners+7 more
Immune Onc is a biotechnology company developing medicines to treat patients with hard-to-treat cancers and autoimmune diseases, with expertise in translational medicine and clinical development.
BiotechMedical DevicesPalo Alto, US
Xiaoling Charlene Liao(Executive Officer, Director)
BoardGuo-Liang Yu(Director)Liqun Luo(Director)
Co-investorsNorthern Light Venture CapitalShangBay Capital LLCVivo CapitalTriWise Capital
iMicrobes uses synthetic biology to develop cost-effective sustainable materials and replace conventional manufacturing processes.
BiotechCircular EconomyCleantechClimate TechHealthtechNew MaterialsSan Francisco, US
Derek Greenfield(Founder/CEO)inLiz Clarke(Founder/CTO)inNoah Helman(Founder/CSO)in
Co-investorsFirst Bight VenturesJude GomilaJuniperPoint Reyes ManagementY CombinatorAsymmetry Ventures+7 more
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InsideMaps provides 3D property documentation and virtual tour technology for real estate professionals, vacation rentals, hotels, and event spaces.
PropTechSaaS
Co-investorsColopl NextGFR FundRET VenturesUlu Ventures
Neocis develops Yomi, a robotic surgical platform that assists clinicians during dental implant surgery with planning, surgical, and restorative software features.
HealthtechMedical DevicesRoboticsMiami, US
Alon Mozes(CEO & Co-Founder)inJuan Salcedo(Engineering Fellow & Co-Founder)inJUAN SALCEDO(Executive Officer)inALON MOZES(Executive Officer, Director)inDennis Moses(Chief Technical Officer)inAndres Carrillo(VP of Product)in
Co-investorsIntuitive VenturesNorwest Venture PartnersVivo CapitalFlorida Opportunity FundMithril Capital ManagementB Capital Group+4 more
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Sentieon develops optimized bioinformatics algorithms for genomic data processing, particularly for precision medicine applications.
AI & Machine LearningBiotechData & InfrastructureDeep TechHealthtechSan Jose, US
Jun Yein
Co-investorsGRC SinogreenMission BiocapitalTen Coves Capital
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
CENTRILLION BIOSCIENCES, INC.Geli
Exits · 4
3 IPOs · 1 acquisitions · showing 3CompassNYSE: COMPGuardant HealthNASDAQ: GHSynlogicOTC: SYBX
Frequently asked questions
- How many investments has CLI Ventures made?
- CLI Ventures has 22 tracked investments, 4 of which have exited.
- What stage does CLI Ventures invest at?
- CLI Ventures invests at the Seed, Series A, Series B, Series C, Growth, Late Stage stages.
- What sectors does CLI Ventures focus on?
- CLI Ventures focuses on Biotech, Healthtech, PropTech.
- Where is CLI Ventures located?
- CLI Ventures is headquartered in Palo Alto, US.