S32
Venture capitalActively deployingPalo Alto · Series A–Late Stage · 25 people tracked
Also known as SECTION 32, LLC
Investment thesis
S32 operates as a deliberately capital-constrained, high-conviction venture firm that backs a small number of companies by design, reserving meaningful capital, time, and attention for each. Its team of investors and operators emphasizes hands-on support, particularly in recruiting world-class engineering, AI, and go-to-market leaders. The firm invests across artificial intelligence, computational biology, physical AI, infrastructure, cybersecurity, and enterprise, aiming to support obsessive founders building iconic companies for the long term.
Source: firm website, verified Aug 3, 2026.
Team · 25 people
from the firm's website & public directories
What they invest in
from 38 of 58 portfolio companiesAI & Machine Learning ×22Enterprise Software ×15SaaS ×9Biotech ×8Deep Tech ×8Developer Tools ×7Cybersecurity ×5Data & Infrastructure ×5
HQs:United States×25Canada×1Germany×1Sweden×1
Investments · 58 tracked
founders shown can be your intro path
Coinbase is a cryptocurrency exchange platform that offers trading, custody, and financial services for cryptocurrencies, stocks, derivatives, and prediction markets to consumers, institutions, and developers.
Crypto & Web3FintechLos Angeles, US
Brian Armstrong(Founder/CEO)in
Infleqtion designs and manufactures neutral atom quantum computers, quantum sensors, and software for governments, corporations, and research institutions.
Deep TechDefense TechQuantum ComputingLouisville, US
Catherine P. Lego(Director)Pranav Gokhale(Chief Technology Officer)Dawn C. Meyerriecks(Director)Kristina M. Johnson(Director)Paul Lipman(Chief Revenue Officer)Jason D. Hall(Chief Legal Officer)
Uber operates a multi-sided platform providing ride-sharing, food delivery, freight logistics, and business fleet management services across various global markets.
Logistics & Supply ChainMarketplacesMobility & TransportationSan Francisco, US
Travis Kalanick(Co-founder & CEO)Garrett Camp(Co-founder)
humans& is a frontier AI lab focused on building human-centric AI systems that prioritize people and their relationships, emphasizing innovations in reinforcement learning, memory, and user understanding to create AI that strengthens organizations and communities.
AI & Machine LearningEnterprise SoftwareSaaSEl Segundo, US
Eric Zelikman(Co-founder)Alaarif Nooruldeen(Executive Officer, Director)Kristen Green(Director)Allen Mask(Director)Jonathan Ellman(Director)Eduardo Vivas(Director)
NewLimit develops epigenetic reprogramming medicines to extend healthspan and treat age-related diseases at the intersection of computer science and biotechnology.
AI & Machine LearningBiotechLongevity
Brian Armstrong(Co-founder, Board of Directors)Blake Byers(Director)Jacob Kimmel(Director)Michael Polansky(Executive Officer)
BoardZavain Dar(Director)
Los Angeles, US
Howard Lewin(Executive Officer, Director)Andrew Harrison(Director)Glenn Rosenthal(Director)
Board seatAndrew ConradMike Pellini· per SEC Form D · $25.4M raise · filed Nov 2022
Medcrypt provides cybersecurity products and strategic consulting to medical device manufacturers to ensure devices are secure by design and meet regulatory requirements.
CybersecurityHealthtechMedical DevicesSaaSSan Diego, US
Mike Kijewski(Founder)inEric Pancoast(Founder)in
Board seatAndrew ConradMike Pellini· per SEC Form D · $8.7M raise · filed Feb 2025
San Francisco, US
Board seatAinhoa Maiz· per SEC Form D · $10M raise · filed Sep 2021
TwinStrand develops Duplex Sequencing technology, a genomic platform for improving accuracy in clinical medicine and life sciences research applications.
BiotechData & InfrastructureDeep TechMedical DevicesSeattle, US
Chad Waite(Director)Jesse Salk(Executive Officer, Director, Promoter)Kellie Bickel(Executive Officer)Michael Pellini(Director)Steve Dow(Director)Soma Somasegar(Director)
Board seatMike Pellini· per SEC Form D · $25.7M raise · filed Jun 2023
8090 is an AI-native software development platform designed for regulated enterprises in healthcare, financial services, manufacturing, and government that enables teams to build production code from business intent with full audit trails and governance controls.
AI & Machine LearningDeveloper ToolsEnterprise Software
Chamath Palihapitiya(Co-founder and CEO)
Aspen Neuroscience develops iPSC-derived autologous cell therapies for neurological diseases, with a lead product (ANPD001) in Phase 1/2a clinical trials for Parkinson's disease.
BiotechDeep TechDigital HealthMedical Devices<UNKNOWN>, US
Andrés Bratt-Leal(Co-Founder and Senior Vice President, Research & Development)Damien McDevitt(President and Chief Executive Officer)
AI research lab developing visual intelligence technology including image generation and manipulation models.
AI & Machine LearningDeep TechDeveloper ToolsFreiburg, DE
Robin Rombach(Founder)Andreas Blattmann(Founder)Patrick Esser(Founder)Anjney Midha(Director)
Brightside provides remote mental health care combining personalized psychiatry and therapy through a technology-enabled platform.
Digital HealthHealthtechMental HealthSan Francisco, US
Bradley Kittredge(Executive Officer, Director)Jeremy Barth(Executive Officer, Director)Eric Wiesen(Director)Aike Ho(Director)
Brightside provides financial wellness services to employees through human Financial Assistants who address personal financial needs including emergency loans, budgeting, credit, and retirement planning.
Enterprise SoftwareFintechHR TechWellness & Fitness
Shawn Leavitt(Founder)
Cohere builds foundational AI models and enterprise solutions that help businesses automate tasks, accelerate workflows, and enhance decision-making.
AI & Machine LearningDeveloper ToolsEnterprise SoftwareSaaSToronto, CA
Aidan Gomez(Co-founder and CEO)Ivan Zhang(Co-founder)Nick Frosst(Co-founder)
Culture Biosciences provides software and bioreactor hardware solutions for bioprocess development, enabling researchers to design, monitor, and analyze experiments remotely with cloud-native analytics and AI/ML insights.
AI & Machine LearningBiotechCloud ComputingHealthtechSan Francisco, US
Databricks provides a unified platform for data engineering, analytics, and artificial intelligence, enabling organizations to build and deploy data and AI applications on cloud infrastructure.
AI & Machine LearningCloud ComputingData & InfrastructureEnterprise SoftwareSan Francisco, US
Ali Ghodsi(Executive Officer, Director, Promoter)Ion Stoica(Executive Officer, Director, Promoter)Matei Zaharia(Executive Officer, Director, Promoter)David Conte(Executive Officer)Tram Phi(Executive Officer)
BoardPeter Sonsini(Director)
EMA is an enterprise platform for building and scaling AI-powered workflows that automatically selects the best combination of models for each task to optimize accuracy, cost, and latency.
AI & Machine LearningEnterprise SoftwareSaaS
Endor Labs provides application security tooling to identify, prioritize, and fix vulnerabilities in software development, with particular focus on securing AI-generated code and open-source dependencies.
AI & Machine LearningCybersecurityDeveloper ToolsPalo Alto, US
Varun Badhwar(Founder & Co-founder)inDimitri Stiliadis(Founder & Co-founder)
CrowdStrike provides cloud-native security software protecting endpoints, cloud workloads, identity systems, and data infrastructure to prevent breaches for enterprise customers.
Cloud ComputingCybersecurityEnterprise Software
George Kurtz(Founder & CEO)
Palo Alto, US
Andreas Stavropoulos(Director)L. William Krause(Director)Brandon Heller(Executive Officer, Director)David Erickson(Executive Officer, Director)
Gretel provides synthetic data generation tools that enable developers to create high-quality, domain-specific datasets for training agentic AI systems and language models.
AI & Machine LearningData & InfrastructureDeveloper ToolsPoway, US
Ali Golshan(Director)Sridhar Ramaswamy(Director)Laszlo Bock(Director)Kelly Perdew(Director)Alexander Watson(Executive Officer, Director)
Gusto provides payroll processing, employee benefits administration, and HR management tools to businesses, offering integrated software alongside support services for these functions.
Enterprise SoftwareHR TechSan Francisco, US
Josh Reeves(Founder/CEO)inEdward Kim(Founder/Empowering Gusto's Engineering Team)inTomer London(Founder/; Empowering Gusto's Product and Design Teams)in
Inceptive builds foundation models of biological systems for drug discovery, specializing in sequence-based medicines like mRNA and peptides.
AI & Machine LearningBiotechMedical DevicesPalo Alto, US
Jakob Uszkoreit(Executive Officer, Director, Promoter)Kevin Heyries(Executive Officer)Vijay S. Pande(Director)Diana Isabel Ajuria(Executive Officer)Do Soon Kim(Executive Officer)
Inductive Bio builds AI and machine learning software to accelerate drug discovery for pharmaceutical and biotech researchers, combining computational chemistry with expertise in translating complex drug programs from preclinical to clinical stages.
AI & Machine LearningBiotechDeep TechBrooklyn, US
Josh Haimson(Executive Officer, Director)inBen Birnbaum(Ph.D.)inAlexander Taylor(Ph.D.)inRohan Ganesh(Director)
AI engine powering next-gen video games and interactive experiences
Google Nest manufactures smart home devices including cameras, doorbells, speakers, and thermostats that integrate with Google Home for security, entertainment, and energy management.
ConsumerHardwareIoTMountain View, US
BiotechFremont, US
Jared Birchall(Executive Officer, Director)ELON MUSK(Executive Officer)
Ohalo develops agricultural products designed to improve farmer productivity and livelihoods globally.
AgTechBiotech
Phaidra develops an AI control platform that uses reinforcement learning to optimize energy efficiency and operational performance in data centers and AI factories.
AI & Machine LearningCloud ComputingDeep TechEnergy
Jim Gao(Chief Executive Officer)inVeda Panneershelvam(Chief Technology Officer)inKatie Hoffman(President and Chief Operating Officer)in
Physical Intelligence develops generalist AI models for robotics that can control any robot to perform various tasks through learning algorithms and multi-robot training.
AI & Machine LearningDeep TechRobotics
Sergey Levine(Founder)
RunSybil provides AI-powered active defense and offensive security capabilities for enterprise security teams, automating hacker-level threat detection and response.
AI & Machine LearningCybersecuritySan Francisco, US
Brian Byun(Director)Ari Herbert-Voss(Executive Officer, Director)in
SandboxAQ combines artificial intelligence and quantum technology to address complex industrial challenges.
AI & Machine LearningDeep TechQuantum Computing
Sergey Brin(Founder)
Sooth builds an AI-powered global foresight engine that delivers reliable probabilistic forecasts to help organizations make strategic decisions under uncertainty by analyzing interconnected risks across markets, supply chains, and geopolitical events.
AI & Machine LearningData & InfrastructureEnterprise Software
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.
Frequently asked questions
- What stage does S32 invest at?
- S32 invests at the Series A, Series B, Series C, Growth, Late Stage stages.
- What sectors does S32 focus on?
- S32 focuses on AI & Machine Learning, Biotech, Cybersecurity, Data & Infrastructure, Deep Tech, Enterprise Software, Fintech, Healthtech, Robotics, SaaS.
- Where is S32 located?
- S32 is headquartered in Palo Alto, US.
- Does S32 lead rounds?
- S32 typically participates in rounds rather than leading them.
Co-investors · 52
Andreessen Horowitz's Strategic Partnerships page describes collaborations that connect its portfolio companies with established institutions to help scale and deploy their technology.
GV (formerly Google Ventures) is a venture investment firm that backs founders across many industries, aiming to build long-term relationships and support companies across multiple stages and milestones.
Sequoia Capital is a venture capital firm that partners with founders to build technology companies, with a strong current focus on artificial intelligence.
General Catalyst is a venture capital and investment firm that backs founders across industries, with a strong focus on AI-driven transformation, fintech, healthcare, and other sectors.
Accel is a venture capital firm that partners with exceptional founding teams, positioning itself as a first partner to startups globally.
Cota Capital is an investment firm focused on founders building net-new enterprise technology, combining capital with operational expertise, industry insight, competitive intelligence, and a broad network.
Founders Fund is a venture capital firm that invests in companies building transformative technologies across defense, space, data analytics, and other frontier sectors.
Insight Partners is a venture and growth-stage software investor featuring a large portfolio of technology companies across multiple sectors and regions.
Benchmark is a venture capital firm with offices in San Francisco and Woodside that invests in early-stage startups.
Eniac Ventures is a seed-stage venture firm that positions itself as founder-friendly and focused on helping early-stage companies achieve product-market fit.
Innovation Endeavors is an early-stage venture fund that invests in founders and supports venture creation through pre-team and pre-idea programs. The firm provides portfolio companies with access to mentors, advisors, and an entrepreneur ecosystem.
Madrona Venture Group is an early-stage venture capital firm that backs founding teams at seed, early, and acceleration stages, primarily in Seattle, the Bay Area, and beyond.
▶40 more co-investors
Intel CapitalThreshold VenturesARCH Venture PartnersM12 (Microsoft's Venture Fund)XYZ Venture CapitalArtis VenturesPaladin Capital GroupNorthpond VenturesIntuitive VenturesB Capital GroupCRV (Charles River Ventures)Canaan PartnersTodd and Rahul’s Angel FundBuckley Ventures Management Company LlcNot Boring CapitalPolaris PartnersBanana CapitalVibe CapitalMONASHEESMMC VenturesVertex Ventures IsraelHighbury HoldingsKaszek VenturesGreatPoint VenturesPIPELINE CAPITAL PARTNERSS CapitalAdams Street PartnersDeerfield Management CompanySanofi VenturesThird Rock Ventures7wire VenturesGrove VenturesSV Health InvestorsMsd CapitalAlta PartnersaMoonVertical Venture PartnersMerck Global Health Innovation FundCasdin CapitalMcKesson Ventures
Firms observed investing alongside S32, from public investor directories. Shared companies are the overlap with S32's recorded portfolio.
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