Lewis & Clark Ventures
Venture capitalSt. Louis · Seed–Series A · 13 people tracked
Investment thesis
Lewis & Clark Ventures partners with visionary founders to build iconic B2B software companies. The firm invests at the late seed through Series A stages, looking for founders with a big vision, a bold idea, and the ability to build and lead strong teams. Managed by former founders and operators, the firm brings an entrepreneurial mindset and aims to provide portfolio founders with the tools, guidance, and resources they need to succeed. Initial investments typically range from $2M to $3M, with flexibility in either direction.
Source: firm website, verified Aug 3, 2026.
Team · 13 people
from the firm's website & public directoriesWhat they invest in
from 13 of 19 portfolio companiesSaaS ×5AI & Machine Learning ×4Enterprise Software ×3Healthtech ×3AgTech ×2Data & Infrastructure ×2Developer Tools ×2HR Tech ×2
HQs:United States×6
Investments · 19 tracked
founders shown can be your intro pathBy year:2023 · 12022 · 12020 · 13 dated
AI-powered sales enablement solution using natural language processing for top-of-funnel prospecting.
Kansas City, US
Nicholas Smith(Executive Officer, Director)
BoardJean-Luc Vanhulst(Director)John Tedesco(Director)
Board seatMichael Rockhold· per SEC Form D
Beam Benefits is a digitally-native employee benefits company offering dental, vision, life, and supplemental health insurance through an online platform with personalized rewards and AI-powered underwriting.
HealthtechHR TechInsurTechMadison, US
Alex Frommeyer(CEO)Alex CurryDan Dykes
Benson Hill develops genetically optimized soy seed varieties using AI-driven plant science, targeting agricultural producers seeking more nutritious, sustainable, and energy-dense crop solutions.
AgTechAI & Machine LearningNew Materials
ChatLingual provides a cloud-based multilingual AI messaging platform that lets enterprise customer support teams handle conversations in real time across any language and digital channel.
AI & Machine LearningEnterprise SoftwareSaaS
Dalia provides a platform for employers to optimize candidate conversion through career site tools, job matching, and AI-powered support.
HR TechSaaSWestwood, US
Samuel Fitzroy(Executive Officer, Director)Brian Hopcraft(Director)Jason Whitman(Executive Officer, Director)
GreenLight Biosciences develops RNA-based solutions for agriculture and pest control, including a Colorado potato beetle bio-insecticide and a Varroa destructor mite-control product for sustainable food production.
AgTechBiotechImpact & Social GoodMedford, US
Andrey Zarur(Executive Officer, Director)Marta Ortega-Valle(Executive Officer)William Blake(Executive Officer)
BoardDavid Furneaux(Director)Jonathan Fleming(Director)James Swartz(Director)
HealthtechMississauga
Gerard van Hamel Platerink(Director)Gerald Gradwell(Director)Helen Ciesielski(Director)Glen Stettin(Director)Robert C. Faulkner(Director)Michael R. Kramer(Director)
Occuspace develops AI-enabled sensors that detect occupancy and space utilization through wireless signal scanning, without cameras or personal data collection.
AI & Machine LearningIoT
FintechSan Francisco, US
Kevin Irwin(Director)Ashwini Gupta(Director)Dukkyu Park(Director)Soyeon Kim(Executive Officer, Director)
Portfolio news
latest coverage across their companiesBeam Benefits · gurufocus.com · Jul 7, 2026
Bindplane · crainsgrandrapids.com · Apr 16, 2026
Frequently asked questions
- What stage does Lewis & Clark Ventures invest at?
- Lewis & Clark Ventures invests at the Seed, Series A stages.
- What is Lewis & Clark Ventures's typical check size?
- Lewis & Clark Ventures typically writes checks of $2M – $3M.
- What sectors does Lewis & Clark Ventures focus on?
- Lewis & Clark Ventures focuses on Advanced Manufacturing, Energy, Enterprise Software, Fintech, Healthtech, Medical Devices, SaaS.
- Where is Lewis & Clark Ventures located?
- Lewis & Clark Ventures is headquartered in St. Louis, US.
- Does Lewis & Clark Ventures lead rounds?
- Yes, Lewis & Clark Ventures leads investment rounds.
Images
Co-investors · 1
Valor Ventures is an early-stage venture capital firm focused on backing founders in the U.S. South, positioning the region as an under-resourced but fast-growing wealth center. It builds a community connecting founders, investors, and industry leaders through events and research.
Firms observed investing alongside Lewis & Clark Ventures, from public investor directories. Shared companies are the overlap with Lewis & Clark Ventures's recorded portfolio.
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