Data Driven Bioscience

Data Driven Bioscience is a Durham, North Carolina-based cancer genomics company established in 2018 that builds tools enabling clinical laboratories to apply genomics to the diagnosis and treatment of cancers. Its product, Duoseq, is a next-generation sequencing assay and software suite that prepares and analyzes DNA and RNA together in a single workflow from one sample, producing genomic and transcriptomic information simultaneously rather than requiring separate assays.

The workflow is designed to run entirely on-site at the customer lab: sample preparation and library prep occur on day one, sequencing runs overnight, and a Duoseq Suite report is generated on day two. Beyond mutation calling, the dual DNA/RNA approach reports gene expression, fusions and clonotype data. The company positions the assay for automated, robotic lab workflows requiring under 10 minutes of technician time, and states that Duoseq results integrate directly with EPIC and other electronic health record systems so structured molecular data flows into the patient chart.

Founding story

The company was established in 2018 by Sandeep Dave, who serves as founder and CEO.

Business model

The company supplies an assay and analysis platform to clinical laboratories, which run the Duoseq workflow and sequencing in-house rather than sending specimens to a reference lab.

Traction

Y Combinator lists a team size of 10 and an active status, with the company recruiting a bioinformatics specialist. The company's site publishes anonymous customer testimonials citing in-house comprehensive NGS results obtained faster than shipping samples to outside labs, reduced hospitalization days spent awaiting diagnosis, and MolDX and regulatory support.