E12 Venture Capital, Llc
Venture capitalLos Altos · Pre-Seed–Series B · 12 people tracked
Investment thesis
E12 Ventures invests in early-stage companies whose founders bring unique expertise to solving pressing challenges facing global industries. The firm combines the experience of a seasoned seed fund with a later-stage venture team, backed by a group of international investors. It focuses on emerging technologies including artificial intelligence, deep learning, IoT, and robotics, applied across broad industrial sectors such as climate tech, agtech, foodtech, healthtech, fintech, and logistics/supply chain. The firm works closely with founders to craft and execute winning strategies and drive operational excellence.
Source: firm website, verified Aug 25, 2026.
Team · 12 people
from the firm's website
What they invest in
from 13 of 13 portfolio companiesAI & Machine Learning ×6Healthtech ×5Cleantech ×3Digital Health ×3Advanced Manufacturing ×2Biotech ×2Climate Tech ×2Consumer ×2
HQs:United States×12
Who they back
founder profiles across 12 portfolio companiesFounding team size:solo founder×22 founders×63 founders×24+ founders×2
Where their founders studiedfrom 12 founders with education data
Massachusetts Institute of Technology ×4Stanford University ×2
Where their founders worked beforefrom 12 founders with career history
Stanford University ×3Facebook ×2
Investments · 13 tracked
founders shown can be your intro pathBy year:2017 · 12015 · 12 dated
Archetype AI builds Physical AI for real-world operations, centered on Newton, a proprietary foundation model that fuses multi-sensor data to perceive and reason about physical environments.
AI & Machine LearningDeep TechIoTSan Mateo, US
Ivan Poupyrev, PhD(Founder)inNick Gillian(Founder)inJaime Lien(Founder)inBrandon Barbello(Founder)inIvan Poupyrev(Founder)inLeonardo Giusti(Founder)in
Co-investorsEarl Grey CapitalHitachi VenturesStrange VenturesSystemiq CapitalTrajectory VenturesVenrock+1 more
C16 Biosciences produces high-value lipid ingredients using fermentation of naturally occurring microorganisms for manufacturers of beauty, personal care, home care, and food products.
BiotechCleantechClimate TechConsumerHealthtechNew MaterialsNew York City, US
Shara Ticku(Founder/CEO)inDavid Heller(Founder)inHarry McNamara(Founder)in
BoardAndrew Shumaker(He resigned as a Director effective November 20, 2018.)
Co-investorsBreakthrough Energy VenturesDCVC (Data Collective)Dorm RoomEvolution VC PartnersSinai Capital PartnersUpHonest Capital+2 more
Ciba Health offers an AI-powered virtual platform for managing and reversing chronic conditions such as type 2 diabetes, obesity, metabolic dysfunction, GI, autoimmune, and mental health issues.
AI & Machine LearningDigital HealthHealthtechNew York, US
Innocent Clement(Executive Officer, Director)
BoardMiraj Sanghvi(Director)inPeter Lee(Director)
Co-investors3CC | Third Culture CapitalDigiTx Partners LLCManchesterStory Group, LLC
Ellipsis Health builds Sage, an AI voice agent designed to support healthcare organizations by handling patient interactions and expanding clinical capacity.
AI & Machine LearningDigital HealthHealthtechSan Francisco, US
Mike Aratow(Director)Mainul Islam(Executive Officer, Director)Mainul Mondal(Founder)in
BoardMarie Hurabiell(Director)
Co-investorsAble PartnersAIX VenturesCity LightCVS Health VenturesEquitage Ventures, L.L.C.Generator Ventures+2 more
Fiddler AI provides an AI observability and control platform offering experiments, monitoring, guardrails, and governance for enterprise AI agents and compound AI systems.
AI & Machine LearningData & InfrastructureEnterprise SoftwarePalo Alto, US
Krishna Gade(Founder & CEO)in
Co-investorsAngel Collective Opportunity FundaVentureBenhamou Global VenturesCisco InvestmentsDentsu VenturesIn-Q-Tel+20 more
First Resonance develops ION, a manufacturing execution system (MES) for hardware engineering teams that manages processes from prototype to production, including inventory, assembly, inspection, and analytics.
Advanced ManufacturingHardwareSaaSLos Angeles, US
Karan Talati(Executive Officer, Director)Neal Sarraf(Executive Officer, Director)
BoardVaughn Blake(Director)inMichael Kim(Director)inBlake Vaughn(Director)Eric Manlunas(Director)
Co-investorsBlue Bear Capital PartnersCraft VenturesFikaFrontier Venture CapitalGaruda VenturesIndustrious Ventures+2 more
Neura Health provides telemedicine video visits with board-certified neurologists for conditions including migraine, epilepsy, sleep disorders, tremor, concussion, and stroke.
Digital HealthHealthtechNew York, US
Sameer Madan(Founder)inElizabeth Burstein(Founder)in
Co-investorsCorrelation VenturesKoch Disruptive TechnologiesMitsui Global InvestmentNext Play Ventures
One.bio develops food products designed to provide beneficial molecular signals to support health and address chronic inflammatory disease.
BiotechFoodTechHealthtechWellness & Fitness
Matt Amicucci(Co-Founder & Chief Science Officer)Matt Barnard(Co-Founder & CEO)
Co-investorsAcre Venture PartnersAlpha EdisonBetter Ventures Central LlcCollaborative FundDoon CapitaliSelect Fund+4 more
Pattern Labs develops autonomous robotics and software systems for airport ground operations and dynamic logistics.
AI & Machine LearningLogistics & Supply ChainRoboticsErie, US
John Pratt(Founder)inMatt Fedick(Founder)
Co-investorsOrigin VenturesRPS VenturesService Provider Capital
Rhino Federated Computing provides enterprise software infrastructure enabling organizations to run AI, analytics, and data workflows across distributed data environments while preserving privacy and security.
AI & Machine LearningData & InfrastructureEnterprise SoftwareBoston, US
Dr. Ittai DayaninYuval Baror(Founder)
Co-investorsAlleyCorpFusionLionBirdMitsui Global InvestmentAlley Robotics VenturesVolution Ventures
TELO Trucks builds the MT1, an all-electric compact pickup that combines pickup-truck utility with EV range and advanced safety technology in a subcompact footprint.
CleantechHardwareMobility & Transportation
Co-investorsGoAhead VenturesSpero VenturesTO VC
Oishii operates indoor vertical farms that grow premium produce, including its Omakase Berry, strawberry products, and Rubī Tomato, distributed to consumers and retailers such as Whole Foods across the New York metropolitan area, New Jersey, Connecticut, and D.C.
AgTechConsumerFoodTechNew York, US
Hiroki Koga(Co-founder)Brendan Somerville(Co-founder)Morgan Steffy(Executive Officer, Director)Evan Katz(Executive Officer, Director)
BoardEric Mathews(Director)Joel Seligstein(Director)
Co-investorsCeres PartnersOrbia VenturesREMUS CapitalRoot Ventures Manager, LlcUnion Grove Venture Partners
Unspun develops 3D weaving technology and software for apparel and textile manufacturing, enabling fast, automated, and low-waste garment production for brands and manufacturers.
Advanced ManufacturingCleantechClimate TechEmeryville, US
Kevin Peter Martin(Executive Officer, Director)Walden Hoi Ming Lam(Executive Officer, Director)Beth Esponnette(Founder)inKevin Martin(Founder)inARNE ARENS(Executive Officer, Director)
BoardMilo Werner(Director)in
Co-investorsCity LightDCVC (Data Collective)Evolution VenturesFifty YearsKyber Knight CapitalLOWERCARBON+7 more
Portfolio news
latest coverage across their companiesFirst Resonance · norfolkdailynews.com · Jul 15, 2026
Unspun · ecotextile.com · Apr 10, 2026
Fiddler AI · thesaasnews.com · Jan 30, 2026
Ellipsis Health · impactalpha.com · Jun 16, 2025
Frequently asked questions
- How many investments has E12 Venture Capital, Llc made?
- E12 Venture Capital, Llc has 13 tracked investments.
- What stage does E12 Venture Capital, Llc invest at?
- E12 Venture Capital, Llc invests at the Pre-Seed, Seed, Series A, Series B stages.
- What sectors does E12 Venture Capital, Llc focus on?
- E12 Venture Capital, Llc focuses on AgTech, AI & Machine Learning, Climate Tech, Deep Tech, Digital Health, Fintech, FoodTech, Healthtech, IoT, Logistics & Supply Chain, Quantum Computing, Robotics.
- Where is E12 Venture Capital, Llc located?
- E12 Venture Capital, Llc is headquartered in Los Altos, US.
- Who does E12 Venture Capital, Llc co-invest with?
- E12 Venture Capital, Llc most often shares deals with City Light, DCVC (Data Collective), Mitsui Global Investment, among 83 tracked co-investors.
Images
Co-investors · 27
Craft Ventures is a venture capital firm run by a team of former founders, operators, and investors who partner closely with founders to help build and scale technology companies.
Lux Capital is a venture capital firm that backs founders building transformative deep technologies, having been among the first investors in category-defining companies across AI, robotics, biotech, defense, and infrastructure.
Trajectory Ventures invests in and partners with innovative founders and companies driving digital transformation, while also providing advisory, growth marketing, financing strategy, and M&A support.
Venrock is a venture capital firm investing across technology and healthcare, backing companies in fintech, developer infrastructure, life sciences, therapeutics, semiconductors, and consumer products.
AIX Ventures is an AI-focused venture fund that backs founders building companies in artificial intelligence.
Andreessen Horowitz (a16z) is a venture capital firm founded in 2009 by Marc Andreessen and Ben Horowitz, known for pioneering the platform model with a large team of operators supporting founders across stages.
Sequoia Capital is a venture capital firm that partners with founders to build technology companies.
Founders Fund is a venture capital firm that backs technology companies building transformative products.
Alumni Ventures (AV) is a venture capital firm that co-invests alongside lead VCs in startups, backing founders with capital and access to a large investor and operator community.
Innovation Endeavors is an early-stage venture fund that invests in founders and supports venture creation through pre-team and pre-idea programs. The firm provides portfolio companies with access to mentors, advisors, and an entrepreneur ecosystem.
Afore Capital is a $500M pre-seed venture fund that invests in pre-traction, early-stage companies, leveraging product and investment expertise to support founders from day zero.
SoftBank Vision Fund invests globally in AI-focused companies working to transform and create industries.
▶15 more co-investors
AdditionGaingelsEntrepreneur FirstEclipse VenturesA.Capital VenturesThirty Five Ventures (35V)Flucas VenturesCyfrinWalden Catalyst8090 IndustriesOne Planet GroupVoLo Earth VenturesStarbridge Venture Capital LlcAngel Operator Partners (aop)Starship Ventures
Firms observed investing alongside E12 Venture Capital, Llc, from public investor directories. Shared companies are the overlap with E12 Venture Capital, Llc's recorded portfolio.
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