Prefix Capital
Venture capitalSan Francisco · Pre-Seed–Seed · 2 people tracked
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Investment thesis
Early-stage VC focused on deep-tech startups building foundational technologies.
Source: firm website, verified Aug 7, 2026.
Team · 2 people
from the firm's websiteWhat they invest in
from 23 of 27 portfolio companiesAI & Machine Learning ×11Data & Infrastructure ×6Enterprise Software ×6Biotech ×5Deep Tech ×5SaaS ×5Climate Tech ×3Cybersecurity ×3
HQs:United States×17China×1United Kingdom×1Ireland×1
Who they back
founder profiles across 12 portfolio companiesFounding team size:solo founder×42 founders×43 founders×24+ founders×2
What their founders studiedfrom 10 founders with field-of-study data
Computer Science ×5Engineering ×2Life Sciences ×2
Accelerator rootsportfolio companies that came through a program
Investments · 27 tracked
founders shown can be your intro pathBy year:2023 · 12022 · 32021 · 42017 · 210 dated
RYTHM, Inc. manufactures and sells hemp-derived THC beverages and edible products under brands including RYTHM, Señorita, incredibles, and Beboe through retail partners, online channels, and direct-to-consumer distribution, and generates licensing revenue by permitting other companies to produce and distribute products under its owned brand names.
Billerica, US
Raymond Chang(Executive Officer, Director)inNiv Krikov(Executive Officer)Matthew S. Kressy(Director)Krishnan Varier(Director)inThomas Massie(Director)Robert Harrison(Executive Officer)
Co-investorsARCADIAN Fund
Intel designs and manufactures semiconductor processors for data center, consumer, and embedded applications, including Xeon server processors, Arc graphics processors, and mobile processors.
AI & Machine LearningHardwareSemiconductorsSanta Clara, US
Robert Noyce(Co-founder)inGordon Moore(Co-founder; CEO 1975–1987)Andrew Grove(Employee no. 3; CEO 1987–1998)April Miller Boise(Executive Vice President and Chief Legal Officer)inMichelle Johnston Holthaus(Chief Executive Officer of Intel Products)inChristoph Schell(Executive Officer)in
Co-investorsAccess Venture PartnersCeltic House Venture PartnersGen CapitalKluz VenturesNorwest Venture PartnersPlayground Global+8 more
Symmetry Systems builds a data and AI security platform that provides visibility and control over data access across cloud, on-premises, and SaaS environments for enterprises.
AI & Machine LearningCybersecurityData & InfrastructureAustin, US
Casen Hunger(Co-founder)inDr. Mohit Tiwari(Co-founder)
Co-investorsForgePoint CapitalAccenture VenturesNelstone VenturesTrousdale VenturesW11 CapitalTSG
Ample builds a modular battery-swapping technology that delivers a full charge to any electric vehicle in under five minutes using lego-like swappable battery modules, without requiring carmakers to redesign their cars.
CleantechEnergyHardwareMobility & Transportation
Co-investorsCivilization Ventures Management, LlcHemi Ventures, LlcJazzya InvestmentsNew Ground VenturesStart CapitalTransform Capital Management+6 more
Base Operations provides a platform for corporate security teams to proactively identify and analyze threats using street-level intelligence and data-driven insights.
AI & Machine LearningCybersecurityData & InfrastructureEnterprise SoftwareSaaSWashington, US
Co-investorsGlasswing VenturesGood Growth CapitalGrotech VenturesInner Loop CapitalMagma PartnersMindset Venture+5 more
Biomemory develops DNA-based data storage systems for data centers, offering an alternative storage tier optimized for long-term archival, density, and energy efficiency.
Climate TechData & InfrastructureDeep Tech
Hyunjun Park(CEO)
Co-investorsCivilization Ventures Management, LlcFifty YearsHemisphere Ventures LLCNew Enterprise Associates (NEA)Z Venture CapitalCantos Ventures+3 more
Diamond Foundry produces lab-grown diamond and diamond wafers for use as a semiconductor material, aiming to enable diamond transistors and electronics.
Deep TechNew MaterialsSemiconductorsSan Francisco, US
Co-investorsAlpha Ascent Ventures LlcInvariantes FundLong Journey VenturesObvious Ventures
Epoch ML builds autonomous AI systems that generate code and automate software development, serving enterprise customers with mission-critical deployments.
AI & Machine LearningDeveloper ToolsEnterprise Software
Idan Beck
Co-investorsTranspose Platform ManagementTrousdale Ventures
Gridspace builds generative voice AI infrastructure for enterprise applications like call centers, healthcare, and collections.
AI & Machine LearningCloud ComputingEnterprise SoftwareSaaSSan Francisco, US
Evan Macmillan(Executive Officer, Director)Omri Dahan(Co-founder, CEO)Anthony Scodary(Co-founder, Co-Head of Engineering)Nico Benitez(Co-founder, Co-Head of Engineering)inMike Piechna(Co-founder, CRO)
Co-investorsBloomberg BetaCommerce VenturesGreat Oaks Venture CapitalMouro CapitalVista Venture PartnersRothenberg Ventures
Invitae provides genetic testing services to patients and clinicians across the United States, offering broad test offerings and genetic counseling to inform health decisions at every stage of life.
BiotechDigital HealthHealthtechMedical DevicesSan Francisco, US
Sean George(Executive Officer, Director)inRandal Scott(Executive Officer, Director)Shelly Guyer(Executive Officer)inLee Bendekgey(Executive Officer)inGeoffrey Crouse(Director)
BoardEric Aguiar(Director)in
Co-investorsCivilization Ventures Management, LlcDecheng CapitalFifty YearsManta Ray VenturesOberland CapitalTech Wildcatters+3 more
Jiko provides T-bill-backed accounts that automatically invest corporate cash in U.S.
Data & InfrastructureEnterprise SoftwareFintechSaaSSan Francisco, US
Stephane Lintner(Founder)in
Co-investors500 GlobalAnthem Venture Management, LlcCore Venture CapitalDigital Currency GroupEmbark VenturesNyca+11 more
Lemonaid Health is a telehealth company that lets patients access medical care and treatment online from home, including services like contraceptive pill prescriptions and UTI treatment.
ConsumerDigital HealthDirect to ConsumerHealthtechSan Francisco, US
Paul Johnson(Founder)in
Co-investorsArtis VenturesCivilization Ventures Management, LlcCorrelation VenturesDaybreak PartnerseGateway CapitalFirebolt Ventures Management Company, Llc+5 more
Manus Bio uses industrial biotechnology and engineered microbial cell factories to produce "BioAlternatives" — sustainable versions of molecules normally sourced from petrochemicals, agriculture, or animal husbandry — and offers a scale-up platform covering cell factory design through biomanufacturing.
BiotechFoodTechNew MaterialsAugusta, US
Ajikumar Parayil(Executive Officer, Director)inAji Parayil(Co-founder)inGreg Stephanopoulos(Co-founder)
BoardJason Whaley(Director)inCarsten Boers(Director)inRichard Goldstein(Director)
Co-investors+ND CapitalAlumni VenturesCivilization Ventures Management, LlcEnergy Impact PartnersLiebenthal VenturesNelstone Ventures+4 more
Neocortix develops technology to address explainability and hallucination issues in large language models, including deep attribution networks for source citation, hallucination detection and mitigation, and royalty allocation based on training data sources.
AI & Machine LearningDeep Tech
Dr. Lloyd Watts(Founder)
Neutrolis is a clinical-stage biotech developing first-in-class therapies that degrade neutrophil extracellular traps (NETs) to address the root cause of autoimmune and inflammatory diseases such as lupus and rheumatoid arthritis.
BiotechHealthtechCambridge, US
Abdul Hakkim Rahamathullah(Director, Executive Officer, Promoter)Toby Fox(Director, Executive Officer, Promoter)
BoardGerald Chan(Director)Anthony Aiudi(Director)John Sundy(Director)
Prellis Biologics runs an antibody discovery platform that uses two-photon laser-bioprinted human immune organoids combined with machine learning to identify fully human antibody therapeutics.
AI & Machine LearningBiotechDeep TechHayward, US
Melanie Matheu(Executive Officer, Director)Noelle Mullin(Executive Officer, Director)in
BoardArvind Gupta(Director)Rohit Sharma(Director)in
Co-investorsBlack Diamond VenturesCelesta CapitalCivilization Ventures Management, LlcOpen Field CapitalCantos VenturesKhosla Ventures+3 more
Gene editing company, with Civilization as founding investor, acquired by Intellia for $200M.
Co-investorsCivilization Ventures Management, Llc
Strikingly is a website builder that enables users to create and publish websites without coding or design experience in under 30 minutes.
Creator EconomyE-commerceEnterprise SoftwareMarketing TechSaaSShanghai, CN
David Haisha Chen(Founder/CEO)inTeng Bao(Founder/CPO)inDafeng Guo(Founder/CTO)in
Co-investorsFundersClubK5 VenturesSv Tech Ventures, Inc.TSVCY CombinatorZillionize+9 more
SwiftComply provides compliance software that automates administrative workflows and data management for water utilities to help them enforce environmental regulations.
CleantechClimate TechFintechGovTechSaaSDublin, IE
Co-investorsM33 GrowthArts AllianceBURNT ISLAND VENTURESHOWZAT PartnersTechstars
Symmetry Laser manufactures laser-cut hypotubes for medical devices, offering custom prototypes and production parts with emphasis on quality, cost, and speed.
Advanced ManufacturingHardwareMedical DevicesDavis, US
Nick(Co-founder)Nicholas Zanobini(Executive Officer, Director, Promoter)
BoardJay Vinson(Director)inGrayson Beck(Director)Trent Tucker(Director)Darren Doud(Director)
Co-investorsForgePoint CapitalTSGW11 Capital
Tractable builds computer-vision and machine-learning AI that performs visual damage assessment from customer images, enabling fast damage appraisals for uses such as accident recovery, car part salvage, and property assessment.
AI & Machine LearningEnterprise SoftwareInsurTechMobility & TransportationLondon, GB
Alexandre Dalyac(Executive Officer, Director)inRazvan Ranca(Executive Officer, Director)inAlex Dalyac(Founding CEO)inAdrien Cohen(Co-Founder, Board Adviser and Former President)inVenkat Sathyamurthy(CEO)in
BoardAshley Fontana(Director)
Co-investorsAcequia Capital (AceCap)Air Street CapitalBeyond CapitalEntrepreneur FirstInsight PartnersIsomer Capital+6 more
VIA provides Web3 technologies to the U.S.
AI & Machine LearningCrypto & Web3CybersecurityData & InfrastructureDefense TechEnergySomerville, US
Katherine Ravanis(Executive Officer)John(Co-inventor of core platform)Colin Gounden(CEO)
BoardAdam Jackson(Director)Alan Parnass(Director)Danny Cotter(Director)in
Co-investorsMassMutual VenturesThe Westly GroupBMW i VenturesBosch VenturesNXT VenturesRobert Bosch Venture Capital
Vidmob provides software to help brand marketing teams discover top-performing creative requirements, maintain consistent brand guidelines across advertising platforms, and manage creative data at scale.
AdTechAI & Machine LearningMarketing TechNew York, US
Alex Collmer(Executive Officer, Director, Promoter)inStephanie Bohn(Executive Officer)inGreg Lieber(Executive Officer)inJason Donnell(Executive Officer, Director)George Rose(Director)Craig Coblenz(Executive Officer)
Co-investors3Spoke CapitalBuildGroupDentsu VenturesDrive by DraftKingseGateway CapitalInterlock Partners+4 more
CesiumAstro develops AI-enhanced, software-defined communications systems for space, air, and ground domain applications.
AI & Machine LearningData & InfrastructureDeep TechDefense TechSpace TechNew York City, US
Daniel Morozoff(Executive Officer, Director)Joseph Ellis(Executive Officer, Director)in
Co-investorsCapital InnovatorsDorm RoomR/GA VenturesSamsung NextSocial StartsTechstars+1 more
Wildtype grows salmon directly from fish cells using cellular agriculture, allowing production of seafood without wild-caught or farmed fish.
BiotechClimate TechFoodTechSan Francisco, US
Justin Kolbeck(Executive Officer, Director)inArye Elfenbein(Director)in
BoardJohn Melas-Kyriazi(Director)
Co-investorsBay Bridge Ventures ClimateCRV (Charles River Ventures)Maven VenturesMission BiocapitalRoot Ventures Manager, LlcS2G Investments+18 more
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
AlignedcarbonPollen Mobile
Exits · 5
2 IPOs · 3 acquisitions · showing 4AgrifyNASDAQ: RYMIntelNASDAQ: INTCLemonaidacq. by 23andmeRewrite Therapeuticsacq. by Intellia
Portfolio news
latest coverage across their companiesJiko · finsmes.com · Oct 8, 2025
Frequently asked questions
- How many investments has Prefix Capital made?
- Prefix Capital has 27 tracked investments, 5 of which have exited.
- What stage does Prefix Capital invest at?
- Prefix Capital invests at the Pre-Seed, Seed stages.
- What sectors does Prefix Capital focus on?
- Prefix Capital focuses on AI & Machine Learning, Biotech, Crypto & Web3, Deep Tech, Semiconductors.
- Where is Prefix Capital located?
- Prefix Capital is headquartered in San Francisco, US.
- Does Prefix Capital lead rounds?
- Prefix Capital typically participates in rounds rather than leading them.
- Who does Prefix Capital co-invest with?
- Prefix Capital most often shares deals with Civilization Ventures Management, Llc, Techstars, Fifty Years, among 91 tracked co-investors.
Co-investors · 65
Techstars is a global startup accelerator and early-stage investor that funds and mentors ambitious founders, providing $220K in capital, a three-month program, and access to a worldwide network of mentors, investors, and corporate partners.
Long Journey Ventures is an early-stage venture firm that backs unconventional, 'magically weird' founders and ideas, positioning itself as a hands-on, community-oriented partner to its companies.
New Enterprise Associates (NEA) is a venture capital firm that invests in and provides long-term support to founders building new companies.
SV Angel is a San Francisco-based firm that invests long-term in founders, supporting them with advice, introductions, and network access at key business inflection points.
True Ventures is an early-stage venture capital firm that has backed founders since 2005, partnering at the earliest moments of company building.
FundersClub is an online venture capital firm and startup investing platform that gives accredited members access to a curated selection of vetted early-stage startups, funding fewer than 2% of the companies it reviews.
Upfront Ventures is an early-stage venture capital firm that invests in and partners with startups over the long term.
TSV Capital (TSVC), formerly TEEC Angel Fund, is a Silicon Valley seed-stage venture firm that backs technical founders at the earliest stages, having invested in over 200 early-stage companies.
Acequia Capital is an early-stage investment platform supporting technical founders and product teams building global technology businesses.
Thomvest is a group of investment companies investing on behalf of Peter J. Thomson and his family, backing entrepreneurs to build industry-defining companies. Its portfolio spans fintech, proptech, cybersecurity and related sectors.
The Westly Group is a family of venture funds backing founders across pre-seed, seed, Series A, and early growth stages, focused on the physical economy.
Andreessen Horowitz (a16z) is a venture capital firm founded in 2009 by Marc Andreessen and Ben Horowitz, known for pioneering the platform model with a large team of operators supporting founders across stages.
▶53 more co-investors
Founders FundNotable CapitalUncork CapitalFJ LabsFirst Round CapitalBoxGroupKrakenDST GlobalEniac VenturesOffline VenturesSlow VenturesHCVCAME Cloud VenturesFreestyle CapitalHeadlineAccel-KKRMadrona Venture GroupLookout VenturesKapor CapitalStellar CapitalSouth Park CommonsBonfire VenturesPractical Venture CapitalLowercase CapitalRidge Ventures01 AdvisorsPear VC75 & SunnyThe Chernin Group (TCG Crypto)CausalBrainchild HoldingsLead Edge CapitalAmerican Express Ventures (Amex)Kohlberg Kravis RobertsFounders' Co-opFormation GroupMorado Venture PartnersSignia Venture PartnersAlsop Louie PartnersAlpaca VCRivet VenturesBuilders VCDeep Fork CapitalIterative Instinct CapitalREMUS CapitalKrillion VenturesUnicorn India VenturesDarco CapitalCoralCMCC GlobalSlauson & Co.Gaorong VenturesNova Founders Capital
Firms observed investing alongside Prefix Capital, from public investor directories. Shared companies are the overlap with Prefix Capital's recorded portfolio.
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