Global Brain
Venture capitalTokyo · Pre-Seed–Late Stage · 14 people tracked
Also known as グローバル・ブレイン株式会社
Investment thesis
Global Brain focuses on creating startups that can succeed globally. It invests across a broad range of sectors and stages, from seed through later-stage companies. Beyond direct investment from its flagship funds (backed by institutional and corporate investors), the firm operates corporate venture capital (CVC) funds and joint-investment programs with operating companies. It provides hands-on support to portfolio companies through a large, internationally experienced team of capitalists and support staff, and runs an accelerator program (GB Xlimit) for pre-Series A startups offering funding, weekly mentorship from top capitalists, workshops, and a Demo Day.
Source: firm website, verified Aug 3, 2026.
Team · 14 people
from the firm's website & public directoriesWhat they invest in
from 290 of 417 portfolio companiesAI & Machine Learning ×92SaaS ×57Enterprise Software ×50Deep Tech ×48Healthtech ×42B2B Marketplaces ×34Hardware ×33Climate Tech ×29
HQs:Japan×167United States×45United Kingdom×6Singapore×6South Korea×4France×3
Investments · 417 tracked
founders shown can be your intro pathSecuritize provides tokenization solutions for real-world assets, serving asset managers, Web3 firms, DAOs, advisors, and investors.
Crypto & Web3Fintech
Carlos Domingo(Founder & CEO)in
Shoulder Innovations develops InSet® glenoid technology for shoulder joint implants that reduce the rocking horse effect and provide mechanical stability, serving patients with severe shoulder arthritis.
HardwareHealthtechMedical DevicesNorthern California, US
Robert Ball(CEO & Executive Chairman)Matthew Ahearn(Chief Operating Officer)Geoff Pardo(Director)Jeff Points(Executive Officer)Paul Buckman(Director)Mike Carusi(Director)
MUSE develops robots to support retail store operations and help employees work more effectively.
AI & Machine LearningEnterprise SoftwareRetail TechRoboticsTokyo, JP
Sakana AI develops frontier AI research and products, including large language models, multi-agent orchestration systems, and AI solutions tailored for Japanese enterprises and public sector organizations.
AI & Machine LearningDeep TechDefense TechTokyo, JP
David Ha(Co-Founder & CEO)Ren Ito(Co-Founder & Chairman)Llion Jones(Co-Founder & CTO)
Vizcab provides a software platform for construction and real estate professionals to measure, optimize, and manage the carbon impact of building projects using life cycle assessment data and machine learning.
AI & Machine LearningClimate TechConstruction TechSaaSParis, FR
Thomas Jusselme(CEO & co-founder)Guillaume Lafont(CSO & co-founder)
Smart Shuzen provides quotation, comparison, and construction support services for large-scale repairs and shared facility work on apartments and buildings, along with building diagnostic services including drone-based facade inspections and building replacement value visualization.
B2B MarketplacesConstruction TechPropTechTokyo, JP
LexxPluss develops autonomous mobile robots and infrastructure systems that enable industrial equipment at factories and logistics hubs to operate independently without human direction.
Advanced ManufacturingLogistics & Supply ChainRoboticsTokyo, JP
Masaya Aso(CEO)
NearMe operates a shared shuttle service powered by proprietary AI that matches people with rides to reduce inefficient transportation and provide affordable, convenient mobility.
AI & Machine LearningB2B MarketplacesMobility & TransportationTokyo, JP
Koichiro Takahara(CEO)Kenji Hosoda(CTO)Naoyuki Matsukura(CFO)Taiki Inoue(CMO)
12 Pharmacy operates veterinary pharmacies that dispense prescription medications and medical supplies for pets in Japan, partnering with animal hospitals to support pet health and owner peace of mind.
HealthtechLogistics & Supply ChainTokyo, JP
Kompany is a compliance and third-party risk management solutions provider that was acquired by Moody's in March 2022, offering entity verification, screening, and risk solutions.
Enterprise SoftwareFintech
A-wave develops medical devices and related software/hardware products for healthcare applications.
AI & Machine LearningHealthtechMedical Devices大阪市, JP
Activ8 produces and operates intellectual properties in the metaverse and XR space, including VTuber management, virtual events, and virtual production services.
Creator EconomyMedia & EntertainmentTokyo, JP
AI model generates synthetic AI-powered models and characters for visual marketing and promotional content across advertising, e-commerce, and social media channels.
AI & Machine LearningCreator EconomyMarketing TechTokyo, JP
AlgaleX develops and sells "Umamo," a fermented food ingredient created using proprietary fermentation technology.
AgTechFoodTechImpact & Social GoodOkinawa, JP
New York City, US
Jason Cohen(Executive Officer, Director, Promoter)Lewis Cohen(Director)Karl Gemperli(Director)
BoardNaoki Kamimaeda(Director)
Anique creates physical and digital merchandise, pop-up experiences, and virtual exhibitions for anime, manga, games, and illustrations, connecting global fans with content from major Japanese publishers.
ConsumerCreator EconomyMarketing TechMedia & EntertainmentTokyo, JP
Kasai Takahide(代表取締役 (Representative Director))
ATOMica operates social coworking spaces designed to foster relationships between people and enable connection and collaboration.
Future of WorkSaaSSocial宮崎市, JP
AuthenX designs optoelectronic components and optical transceiver modules based on III-V and silicon photonics technology for 5G, satellite communications, fiber networks, and data center applications.
Data & InfrastructureDeep TechHardwareSemiconductors
Balance Re provides real-time analytics and quantitative asset-liability management solutions to help life insurers and pension funds manage capital, liquidity, and investment risks through proprietary technology.
Data & InfrastructureFintechInsurTechKöln, DE
Lucian Rautu(Co-CEO)Michel Gauer(Co-CEO)
Be-FULL uses data and AI to maximize the potential of workers and organizations by achieving performance transformation—balancing individual fulfillment with organizational outcomes through technology and dialogue.
AI & Machine LearningEnterprise SoftwareHR TechTokyo, JP
Ryota Iwai(Founder)
Beacon Power Services provides grid network management and energy consumption solutions for utilities and consumers across Africa, offering platforms for operational optimization and renewable energy integration.
EnergyEnterprise SoftwareIoTChicago, US
ABIMBOLA ADISA(Executive Officer, Director)YEMI ADEGOKE(Executive Officer)SENYO ADU(Executive Officer)ANTIGHA OTU ANTIGHA(Executive Officer)CHRISTINE ADEJOROOLUWA(Executive Officer)
BoardCyril Collon(Director)
Beatrust provides a comprehensive solution that uses generative AI to visualize employee skills and experience from internal information, enabling collaboration and optimizing human capital allocation within organizations.
AI & Machine LearningEnterprise SoftwareHR Tech
Blank Beauty is a direct-to-consumer nail polish brand that manufactures and sells custom-colored, non-toxic nail polish directly to consumers at reduced prices by eliminating middlemen.
ConsumerDirect to ConsumerCollierville, US
CHARLES C. BRANDON(Executive Officer)
MedRhythms develops digital therapeutics using music, sensors, and software combined with neuroscience to improve walking and mobility in patients with neurological conditions including stroke, multiple sclerosis, and Parkinson's disease.
AI & Machine LearningDigital HealthMedical DevicesBoston, US
Brian Harris(Co-Founder and CEO)Owen McCarthy(Executive Officer, Director)Raymond Pawlicki(Director)
BoardWilliam McKee(Director)Isaac Cheng(Director)Peter J. Werth(Director)
The company develops non-cathartic virtual colonoscopy technology to enable early detection of colorectal cancer, which ranks first in cancer incidence and second in cancer mortality in Japan.
AI & Machine LearningDigital HealthHealthtechMedical Devices
Branch Technology uses patented digital fabrication and additive manufacturing to enable architects and designers to construct complex structural designs at scale.
Advanced ManufacturingConstruction TechDeep TechHardwareChattanooga, US
Ryan Lusk(Chief Executive Officer)in
Media & Entertainment
Bytebeam provides a platform for building and managing IoT devices for enterprises developing smart hardware products.
Cloud ComputingDeveloper ToolsHardwareIoTSaaS<UNKNOWN>
Gautam BT(Co-Founder & CEO)Ravi Teja(Co-Founder & CTO)Bharadwaaj R(Co-Founder & VP-Embedded)Achal Kothari(Co-Founder & VP-Business)
Cala Health develops non-invasive prescription therapies for movement disorders, starting with a treatment for hand tremor and essential tremor.
Deep TechDigital HealthHealthtechMedical DevicesSilicon Valley, US
Kate Rosenbluth, PhD(President & Chief Innovation Officer)Deanna Harshbarger(Chief Executive Officer)
ChromaCode develops a High-Definition PCR (HDPCR) multiplexing platform that enables genomic solutions for oncology and precision medicine, offering faster results and cost-effective workflows through automated interpretation and cloud-based software.
AI & Machine LearningBiotechHealthtechMedical DevicesCarlsbad, US
Aditya Rajagopal(Director)Paul Flook(Executive Officer, Director)James C. Blair(Director)Gregory J. Gosch(Executive Officer, Director)Axel Scherer(Director)Alexander G. Dickinson(Director)
CloudPick develops AI-powered checkout and inventory management solutions for retail stores using computer vision and machine learning.
AI & Machine LearningIoTRetail TechShanghai, CN
Alex Ng(Founder)Jeff Feng(Founder & CEO)
Browse all 417 investments with full details →
▶217 more tracked companies
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Frequently asked questions
- What stage does Global Brain invest at?
- Global Brain invests at the Pre-Seed, Seed, Series A, Series B, Series C, Growth, Late Stage stages.
- What is Global Brain's typical check size?
- Global Brain typically writes checks of $100K – $184M.
- What sectors does Global Brain focus on?
- Global Brain focuses on Sector Agnostic.
- Where is Global Brain located?
- Global Brain is headquartered in Tokyo, JP.
- Does Global Brain lead rounds?
- Yes, Global Brain leads investment rounds.
Media · Podcasts & interviews
from their channel【高輪地球益ファンドの実態】TAKANAWA GATEWAY CITYでの実証実験50件超/環境・モビリティ・ヘルスケア中心に幅広く投資/マルチLPの強み/海外展開も手厚く支援/100年続くまちづくり
Global Brain
【スタートアップの知財戦略】なぜスタートアップに知財戦略が必要なのか/知財活動の目標設定と必要な実行体制/知財を活かしたスタートアップ事例/GB知財チームの支援体制と実績
Global Brain
【シリーズA資金調達への軌跡】急成長LOOV内田CEO登場/なぜ今「聞きパ」が求められるのか/リブランディングと今後の戦略/GB Xlimitの魅力と活用法/5th Batch募集中
Global Brain
【スタートアップ転職の新潮流】GBの採用支援チームが提供する転職支援サービス「GB Innovators Lounge」/VCならではの高解像度な企業情報を提供/求職者目線のマッチング/採用支援の全貌
Global Brain
【シリーズAの資金調達を成功へ】GB主催アクセラ 「GB Xlimit 」5th Batch募集開始/全方位型の徹底支援や先輩起業家・大企業と繋がるオープンネットワークなど充実したプログラム
Global Brain
"GB Xlimit" 5th Batch | Key Features & Apply
Global Brain
Images
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