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Cantos Ventures

San Francisco Β· Pre-Seed–Series B Β· 4 people tracked

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Investment thesis

Cantos invests in exceptional founders developing transformative technologies across three strategic pillars: abundance (providing shelter, food, water, energy, health at improved cost or efficiency), resilience (strengthening critical infrastructure and ecosystems), and advantage (advancing US competitiveness in advanced technologies and critical resources). The firm targets rare, relentless individuals capable of building the future outside Silicon Valley's conventional focus areas.

Source: firm website, verified Jul 20, 2026.

Stage
Pre-Seed–Series B
HQ
San Francisco, US
Leads rounds
Leads
Founded
2016
Tracked investments
16

Team Β· 4 people

from the firm's website
Ian RountreeΒ· General Partner

Founder of Cantos in 2016 with a vision to invest in innovation across industries and three-dimensional technology applications. Previously worked on early-stage teams at Invisible Technologies and SoFi.

Grant GregoryΒ· Partner

Joined Cantos in 2024 from a16z's American Dynamism team where he led investments including Castelion and Salient Motion. Serves as Board Director at Shinkei and The Lumber Manufactory. Earlier experience includes a Susa Fellowship and work on MetLife's Private Capital team.

Amee KapadiaΒ· Principal

Joined Cantos in 2021 and leads investments across AI, biotech, and robotics. Co-founded Decoding Bio and the AIxBio Summit. Holds an MS in Biomedical Engineering from Johns Hopkins and an MBA from Stanford.

Sofia GarciaΒ· CFO

Leads finance and operations at Cantos. Previously managed back office functions at Slow Ventures, Bracket Capital, and JLL Spark, and spent three years at J.P. Morgan as a program manager and one year at UBS.

What they invest in

from 12 of 16 portfolio companies

Advanced Manufacturing Γ—7Hardware Γ—7AI & Machine Learning Γ—5Deep Tech Γ—5Defense Tech Γ—4Biotech Γ—3AgTech Γ—2Cleantech Γ—2

HQs:United StatesΓ—8CanadaΓ—1United KingdomΓ—1

Investments Β· 16 tracked

founders shown can be your intro path
Phenomic AIphenomic.aiβœ“ verified

Phenomic AI is a biotech company developing therapies for solid tumors using a machine-learning-powered transcriptomics platform that analyzes single-cell RNA data to identify drug targets and understand tumor biology. The company develops antibody-based therapies informed by its analysis of cell-cell interactions in tumor microenvironments, with current programs targeting stromal and immune components of difficult-to-treat cancers.

AI & Machine LearningBiotechDeep TechToronto, CA

Sam Cooper(Co-founder & CTO)Oren Kraus(Co-founder)

Andean Systemsandean.systemsin
Arborarbor.co
Autonomous flightskyryse.com

Skyryse develops aircraft control systems and software for helicopters and aircraft, offering simplified pilot interfaces, autonomous capabilities, and emergency management features. The system serves military, law enforcement, emergency medical, and disaster response operators.

Defense TechHardwareRobotics

Castelioncastelion.com

Castelion develops advanced strike systems and defense hardware with a focus on rapid iteration and scalable manufacturing to reduce costs and development timelines for U.S. defense applications. The company aims to restore American industrial agility in weapons development and strengthen national security capabilities.

Advanced ManufacturingDefense TechHardwareTorrance, US

Bryon Hargis(Co-Founder & CEO)Sean Pitt(Co-Founder & COO)Andrew Kreitz(Co-Founder & CFO)

EARTH AIearth-ai.comin𝕏

Earth AI uses AI to locate critical mineral deposits by analyzing geological data, supporting the supply chain for hardware and emerging technologies.

Advanced ManufacturingAI & Machine LearningClimate TechDeep TechNew MaterialsSan Francisco, US

Roman Teslyuk(Founder)in

Nerosneros.tech

Neros manufactures tactical unmanned aerial systems and FPV drones for military use, designed for performance, modularity, and secure supply chain operations. The company produces attritable, one-way drones and related ground control systems with integrated electronic warfare resistance for Western military forces.

AI & Machine LearningDefense TechHardwareEl Segundo, US

Pilgrimpilgrimlabs.com
Radiantradiantnuclear.comin𝕏

Radiant Nuclear develops Kaleidos, a portable nuclear microreactor designed to replace diesel generators for remote locations and provide resilient backup power to hospitals, datacenters, and military installations.

Deep TechEnergyHardware

Salient Motionsalientmotion.comin

Salient Motion designs and manufactures critical actuation systems for commercial aviation and defense applications. The company combines in-house motion control expertise across software and hardware to offer faster certification and delivery compared to legacy suppliers.

Advanced ManufacturingDefense TechHardwareSouthern California, US

Vishaal Mali(Chief Executive Officer)

Shinkei Systemsshinkei.systemsin𝕏

Shinkei deploys robotics and computer vision hardware on commercial fishing vessels to process seafood at sea, improving quality and traceability while reducing America's seafood import reliance. The company vertically integrates the supply chain from harvest to consumer, offering real-time visibility and quality control through onboard and fleet-wide software systems.

Advanced ManufacturingAgTechAI & Machine LearningFoodTechHardwareRoboticsLos Angeles, US

Saif Khawaja(Founder)in

Sixfold Biosciencesixfold.bioin𝕏

Sixfold develops RNA delivery technology for the biotech industry. The company was founded by an oncologist and plant scientist and focuses on advancing RNA-based therapeutic approaches through proprietary delivery methods.

AI & Machine LearningBiotechDeep TechHealthtechMedical DevicesLondon, GB

George Foot(Founder)inAnna Perdrix Rosell(Founder)inDr. Anna Perdrix Rosell(Co-founder)Dr. George Foot(Co-founder)

Solugensolugen.comin𝕏

Solugen develops a biomanufacturing platform using fermentation and bioprocessing technology to produce specialty chemicals at scale. The company serves customers in energy, chemicals, and related industries with cost-effective alternatives to traditional petrochemical-based manufacturing.

Advanced ManufacturingBiotechCleantechClimate TechHealthtechHouston, US

Sean Hunt(Co-founder)inGaurab Chakrabarti(Co-founder & CEO)in

The Lumber Manufactorylumbermanufactory.com

TLM builds and operates a network of regional sawmills that process timber and strengthen the domestic lumber supply chain. The company's repeatable technology platform addresses timber utilization and supports rural economic development and forest health.

Advanced ManufacturingAgTechCleantechConstruction Tech

Vital Lyfevital-lyfe.comin𝕏
Website Linkastranis.comin𝕏

Astranis manufactures small, high-powered geosynchronous satellites equipped with advanced digital processing technology for global telecommunications and connectivity services.

Advanced ManufacturingDeep TechHardwareSpace TechSan Francisco, US

John Gedmark(Founder/CEO)inRyan McLinko(Founder/CTO)in

Frequently asked questions

What stage does Cantos Ventures invest at?
Cantos Ventures invests at the Pre-Seed, Seed, Series A, Series B stages.
What sectors does Cantos Ventures focus on?
Cantos Ventures focuses on Advanced Manufacturing, Cleantech, Climate Tech, Deep Tech, Defense Tech, Energy, Hardware, New Materials, Robotics, Semiconductors.
Where is Cantos Ventures located?
Cantos Ventures is headquartered in San Francisco, US.
Does Cantos Ventures lead rounds?
Yes, Cantos Ventures leads investment rounds.

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