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BioGenerator Ventures

Venture capital

St. Louis Β· Pre-Seed–Series B Β· 1 people tracked

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Investment thesis

BioGenerator Ventures provides catalytic investments to life sciences companies across human health and plant/agriculture sciences, including therapeutics, diagnostics, medical devices, research tools, and healthcare. It combines funding with the BioGenerator Labs engine of company-building resources β€” technology, talent, proof-of-concept grants, coaching, grant training, and laboratory space β€” to accelerate new ventures. The firm often supports companies from pre-company licensing and formation through early financing rounds, leading initial financings, orchestrating additional investors, and running diligence processes. It is closely tied to the St. Louis innovation ecosystem and frequently spins ventures out of local academic institutions.

Source: firm website, verified Aug 3, 2026.

Stage
Pre-Seed–Series B
Check
$50K – $250K
HQ
St. Louis, Missouri, US
Leads rounds
Leads
Instruments
Equity Β· Grants
Founded
2003
Tracked investments
26

Team Β· 1 people

from the firm's website
Martha SchlicherΒ· EIR, Impetus CEO, Solis Chair, Plastomics Chair

What they invest in

from 20 of 26 portfolio companies

Biotech Γ—16Medical Devices Γ—12Healthtech Γ—10Deep Tech Γ—7AI & Machine Learning Γ—6AgTech Γ—4Digital Health Γ—3Cleantech Γ—2

HQs:United StatesΓ—15

Investments Β· 26 tracked

founders shown can be your intro path
Pairidex, Inc.pairidex.cominβœ“ verified

Pairidex develops a tumor-informed droplet digital PCR (ddPCR) fusion assay for detecting and monitoring blood cancer, aimed at cancer surveillance and therapeutic monitoring of gene fusion-driven disease.

BiotechHealthtechMedical DevicesSt. Louis, US

Allyson Mayer(Interim COO)Andrew Young(Founder & CSO)Paul Kortschak(CEO)Grant Challen(Co-Founder & Scientific Advisor)

BoardTodd Druley(Director)

Board seatCrystal WinkelerΒ· per SEC Form D

Myonidcadrebioscience.comβœ“ verified

Cadre Bioscience partners with innovators to develop and bring new therapeutics to clinical application through drug development.

BiotechDeep TechHealthtechMedical DevicesSt. Louis, US

Bob Karr(Executive Chairman & CEO)

39N agtech district39northstl.com
Arch Oncology Incarchoncology.com
Benson Hill Inc.bensonhill.com

Benson Hill develops genetically optimized soy seed varieties using AI-driven plant science, targeting agricultural producers seeking more nutritious, sustainable, and energy-dense crop solutions.

AgTechAI & Machine LearningNew Materials

bioiobioio.techin𝕏

BIOIO develops a genetics-based platform for elucidating drug mechanisms of action, combining decades of research in pharmacology with big data and automation to accelerate drug discovery and development.

AI & Machine LearningBiotechDeep TechLongevity

Dr. Peterson

Canopy Biosciencescanopybiosciences.comin𝕏

Canopy Biosciences (Bruker Spatial Biology) develops spatial biology instruments and assays for analyzing gene expression, RNA, and proteins in tissue samples.

BiotechHealthtechMedical DevicesSaint Louis, US

EDWARD WEINSTEIN(President, Chief Executive Officer and Manager)CRYSTAL WINKELER(Chief Operating Officer)CHARLES BOLTEN(Director)DAVID KINGSLEY(Director)

BoardDAVID SMOLLER(Director)

Confluence

Company supported through pre-company stage to growth

Cortex Innovation Communitycortexstl.orgin𝕏

Cortex is a non-profit innovation district in St.

Enterprise SoftwareGovTechImpact & Social GoodSt. Louis, US

Courier Therapeuticsvalohealth.comin𝕏

Valo Health applies technology and biotech expertise to advance drug discovery processes.

AI & Machine LearningBiotech

CoverCresscovercress.comin𝕏

CoverCress Inc. develops agricultural products and seeds that enable farmers to convert idle winter fields into profitable crops.

AgTechCleantechClimate TechEnergy

Edison Agrosciencesedisonagrosciences.com

Edison Agro Sciences develops bio-based synthetic rubber from sunflower crops as an alternative to petrochemical and natural rubber for industrial applications.

AgTechBiotechCleantechNew MaterialsSt. Louis, US

David Woodburn(Executive Officer, Director)Matthew B Crisp(Executive Officer, Director)Dan Broderick(Director)Thomas Hohn(Executive Officer, Director)Tom Christensen(Executive Officer, Director, Promoter)

BoardMatt Helms(Director)

Galera
Geneoscopy

Clinical diagnostics company demonstrating high sensitivity and specificity in pivotal trials

Geneoscopy, Incgeneoscopy.comin𝕏

Geneoscopy develops innovative diagnostic technologies for gastrointestinal health, specifically focused on the detection of colorectal cancer.

BiotechDigital HealthHealthtechMedical DevicesSt. Louis, US

Andrew Barnell(Chief Executive Officer & Co-founder)Erica Barnell(Co-founder)

Immunophotonics, Inc.immunophotonics.comin

Immunophotonics is a clinical-stage biotech company developing novel treatments for solid-tumor cancers and infectious diseases by combining tumor ablation with systemic cancer immunotherapy.

BiotechDeep TechDigital HealthMedical DevicesSt. Louis, US

Dr. Hode(Co-Founder & Senior Fellow)Mr. Alleruzzo(Co-Founder & Director)Dr. Chen(Co-Founder)Dr. Robert Nordquist(Co-Founder)David Smoller(Director)Charlie Bolten(Director)

KaloCytekalocyte.comin

KaloCyte develops ErythroMer, a dried, shelf-stable artificial red blood cell for use in emergency and trauma care when stored blood is unavailable or in short supply.

BiotechDeep TechHealthtechMedical DevicesBaltimore, US

Allan Doctor(Co-Founder & CSO)inDipanjan Pan(Co-Founder, Chief Technical Officer)inPhilip Spinella(Co-Founder, Chief Medical Officer)inDaniel Getman(Director)Gregory Lanza(Director)

Kyphakypha.netin

Kypha develops clinical diagnostic tests for immune system biomarkers, particularly complement activity markers, and provides solutions for real-time immune insights across therapeutic areas.

BiotechDeep TechHealthtechMedical DevicesSt. Louis, US

Nick Staten(Executive Officer)T. Scott Glover(Executive Officer)James D. Marselis(Director)Peter Reinecke(Director)Jonathan Sackier(Director)David Smoller(Director)

MediBeacon Inc.medibeacon.comin𝕏

MediBeacon develops biocompatible fluorescent tracer agents detected by skin sensors for clinical diagnostic applications including kidney function assessment and gastrointestinal permeability measurement.

AI & Machine LearningBiotechHealthtechMedical DevicesSaint Louis, US

Richard Dorshow(Executive Officer, Director)Terence Stern(Executive Officer)Steven Hanley(Executive Officer, Director)Richard Lytle(Director)Charles Bolten(Director)John A. Friel(Director)

Omnioseomniose.comin

Omniose develops a platform for bioconjugate vaccine development using glycoconjugation technology to create vaccines against bacterial pathogens like Group B Streptococcus and Klebsiella pneumoniae.

BiotechDeep TechHealthtechMedical DevicesSt. Louis, US

Dr. Harding(Primary Founder)Mario Feldman(Founder, Scientific Founder)Viliam PavliakBenjamin Moutier

BoardDr. SzymanskiDr. Projan

Panome Biopanomebio.comin

Panome Bio provides multi-omics discovery services using mass spectrometry-based metabolomics and proteomics to identify biomarkers and generate mechanistic insights for research institutions and pharmaceutical companies.

AI & Machine LearningBiotechDeep Tech<UNKNOWN>, US

David Smoller(Director)Deval Lashkari(Director)Alexander Herzick(Director)Edward Weinstein(Executive Officer, Director)Tom Cohen(Executive Officer)Rob Capone(Director)

Plastomics, Inc.plastomics.com

Plastomics develops trait delivery technology for agriculture using cell biology, plant tissue culture, transformation, and molecular biology methods.

AgTechBiotechSt. Louis, US

Jeffrey Staub(Executive Officer, Director)Charles Bolten(Director)Dave Duncan(Director)Elizabeth Gallegos(Executive Officer)Brian Clevinger(Director)

BoardMartha Schlicher(Executive Officer, Director)

RhoDxrhodx.comin

RhoDx develops cell-free DNA and RNA enrichment technologies for liquid biopsy cancer diagnostics.

BiotechDigital HealthMedical Devices

Charlie Rodi(Founder and CSO)

SentiARsentiar.com

SentiAR builds CommandEP, an FDA-cleared mixed-reality holographic augmented reality platform for cardiac electrophysiology that converts real-time catheter data into hands-free 3D holograms and virtual screens for electrophysiologists during procedures.

AI & Machine LearningHealthtechMedical DevicesSt. Louis, US

Sean Churchill(Director)Warren Watson(Director)Jonathan Silva(Executive Officer, Director)Berk Tas(Executive Officer, Director)James Patrick Howard(Executive Officer)CMO & Co-Founder (Professor of Pediatrics & Biomedical Engineering, Washington University in St. Louis)(CMO & Co-Founder)

Wugenwugen.com

Allotera (formerly Wugen) develops allogeneic T-cell therapies.

BiotechHealthtechMedical DevicesSt. Louis, US

Ayman Kabakibi(Executive Officer)Drew Dennison(Director)Niall O'Donnell(Director)Bosun Hau(Director)Kevin Li(Director)Peter Kiener(Director)

Frequently asked questions

What stage does BioGenerator Ventures invest at?
BioGenerator Ventures invests at the Pre-Seed, Seed, Series A, Series B stages.
What is BioGenerator Ventures's typical check size?
BioGenerator Ventures typically writes checks of $50K – $250K.
What sectors does BioGenerator Ventures focus on?
BioGenerator Ventures focuses on AgTech, Biotech, Digital Health, FoodTech, Healthtech, Medical Devices.
Where is BioGenerator Ventures located?
BioGenerator Ventures is headquartered in St. Louis, US.
Does BioGenerator Ventures lead rounds?
Yes, BioGenerator Ventures leads investment rounds.

Images

BioGenerator Ventures photo

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