BioGenerator Ventures
Venture capitalSt. Louis · Pre-Seed–Series B · 20 people tracked
Also known as BioGenerator
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Investment thesis
BioGenerator Ventures provides catalytic investments to life sciences companies across human health and plant/agriculture sciences, including therapeutics, diagnostics, medical devices, research tools, and healthcare. It combines funding with the BioGenerator Labs engine of company-building resources — technology, talent, proof-of-concept grants, coaching, grant training, and laboratory space — to accelerate new ventures. The firm often supports companies from pre-company licensing and formation through early financing rounds, leading initial financings, orchestrating additional investors, and running diligence processes. It is closely tied to the St. Louis innovation ecosystem and frequently spins ventures out of local academic institutions.
Source: firm website, verified Sep 20, 2026.
Team · 20 people
from the firm's websiteFounder mafia
3 people who came through BioGenerator Ventures went on to found or lead other companies.
What they invest in
from 26 of 31 portfolio companiesBiotech ×21Healthtech ×14Medical Devices ×14AgTech ×7AI & Machine Learning ×7Deep Tech ×7Digital Health ×5Cleantech ×2
HQs:United States×21
Who they back
founder profiles across 11 portfolio companiesFounding team size:solo founder×62 founders×33 founders×14+ founders×1
Where their founders worked beforefrom 10 founders with career history
Washington University in St. Louis ×2Washington University School of Medicine ×2
Investments · 31 tracked
founders shown can be your intro pathBy year:2025 · 22024 · 22023 · 22022 · 12018 · 22017 · 12015 · 111 dated
Pairidex offers FusionMRD, a personalized digital droplet PCR (ddPCR) assay that detects and quantifies oncogenic gene fusions from a standard peripheral blood sample to monitor treatment response and minimal residual disease in gene fusion-driven blood cancers such as leukemia.
BiotechDigital HealthHealthtechMedical DevicesSt. Louis, US
Grant Challen(Co-Founder & Scientific Advisor)inAllyson Mayer(Interim COO)inAndrew Young(Founder & CSO)Paul Kortschak(CEO)in
BoardTodd Druley(Director)
Board seatCrystal Winkeler· per SEC Form D
Co-investorsiSelect Fund
Cadre Bioscience partners with innovators to develop and bring new therapeutics to clinical application through drug development.
BiotechDeep TechHealthtechMedical DevicesSt. Louis, US
Bob Karr(Executive Chairman & CEO)
Agragene develops Precision-Guided Sterile Insect Technology (pgSIT) marketed as KNOCKOUT™, a biocontrol product for controlling crop insect pests such as Spotted Wing Drosophila while reducing reliance on traditional insecticides.
AgTechBiotechClimate TechSan Diego, US
Bryan Witherbee(President and CEO)inTracy Ellis(Executive Officer)Clyde Shores(Executive Officer, Director)Robert Schmidt(Director)Gordon Alton(Executive Officer, Director)David Webb(Director)
Co-investorsMissouri Technology CorporationOspraie Ag Science
Confluence Genetics (operating at bensonhillbio.com) is a seed innovation company that develops soybean genetics using AI-driven plant science and proprietary tools such as eMERGE Genetics and CropOS.
Durham, US
Matthew B Crisp(Executive Officer, Director)Lee Palles(Executive Officer)inNadine Carozzi(Executive Officer)Todd C Mockler(Executive Officer)Thomas Brutnell(Executive Officer)
BoardDaniel J Broderick(Director)
Co-investorsActivant CapitalAlexandriaCultivation CapitalFall Line CapitalGV (Google Ventures)iSelect Fund+7 more
Benson Hill develops soybean seed varieties using plant genetics and AI-driven plant science to produce more nutritious and energy-dense soy for agriculture and food markets.
AgTechAI & Machine LearningFoodTech
Co-investorsActivant CapitalGV (Google Ventures)iSelect FundLewis & Clark VenturesManta Ray VenturesMercury Fund+3 more
BIOIO develops a genetics-based platform for elucidating drug mechanisms of action, combining decades of research in pharmacology with big data and automation to accelerate drug discovery and development.
AI & Machine LearningBiotechDeep TechLongevity
Dr. Peterson
Co-investorsLifespan Vision VenturesMissouri Technology CorporationquadraScope Venture Fund
Canopy Biosciences (Bruker Spatial Biology) develops spatial biology instruments and assays for analyzing gene expression, RNA, and proteins in tissue samples.
BiotechHealthtechMedical DevicesSaint Louis, US
EDWARD WEINSTEIN(President, Chief Executive Officer and Manager)inCRYSTAL WINKELER(Chief Operating Officer)CHARLES BOLTEN(Director)DAVID KINGSLEY(Director)
BoardDAVID SMOLLER(Director)in
Co-investorsAmpersand
Cofactor Genomics develops predictive diagnostics for cancer immunotherapy using RNA-expression models to characterize tumor microenvironments and predict patient response.
AI & Machine LearningBiotechHealthtechMedical DevicesSt. Louis, US
Dave Messina(Founder/COO)inJarret Glasscock(Founder/CTO)inJarret Glassock(Executive Officer, Director)Jon Armstrong(Director)in
BoardMatthew A. Ocko(Director)inMark Siegel(Director)in
Co-investorsArgonautic VenturesAscension VenturesDCVC (Data Collective)Fifty YearsiSelect FundJude Gomila+11 more
Cortex is an innovation district in St.
Impact & Social GoodSt. Louis, US
CoverCress Inc. develops agricultural products and seeds that enable farmers to convert idle winter fields into profitable crops.
AgTechCleantechClimate TechEnergyOlivette, US
Jim Hedges(CEO)in
Co-investorsFulcrum Global CapitalPrelude VenturesProlog VenturesCultivation Capital
Edison Agro Sciences develops bio-based synthetic rubber from sunflower crops as an alternative to petrochemical and natural rubber for industrial applications.
AgTechBiotechCleantechNew MaterialsSt. Louis, US
David Woodburn(Executive Officer, Director)inMatthew B Crisp(Executive Officer, Director)Thomas Hohn(Executive Officer, Director)inTom Christensen(Executive Officer, Director, Promoter)
BoardDan Broderick(Director)Matt Helms(Director)
Co-investorsArieal Southeast Angel Partners
Geneoscopy develops innovative diagnostic technologies for gastrointestinal health, specifically focused on the detection of colorectal cancer.
BiotechDigital HealthHealthtechMedical DevicesSt. Louis, US
Andrew Barnell(Chief Executive Officer & Co-founder)inErica Barnell(Co-founder)in
Co-investorsDorm RoomiSelect FundMissouri Technology CorporationCultivation Capital
Immunophotonics is a clinical-stage biotech company developing novel treatments for solid-tumor cancers and infectious diseases by combining tumor ablation with systemic cancer immunotherapy.
BiotechDeep TechDigital HealthMedical DevicesSt. Louis, US
Dr. Hode(Co-Founder & Senior Fellow)Mr. Alleruzzo(Co-Founder & Director)Dr. Chen(Co-Founder)Dr. Robert Nordquist(Co-Founder)Luciano Alleruzzo(Director, Promoter)Wei Chen(Director, Promoter)
Co-investorsArgonautic VenturesCentennial InvestorsiSelect FundMissouri Technology CorporationCultivation Capital
KaloCyte develops ErythroMer, a dried, shelf-stable artificial red blood cell for use in emergency and trauma care when stored blood is unavailable or in short supply.
BiotechDeep TechHealthtechMedical DevicesBaltimore, US
Allan Doctor(Co-Founder & CSO)inDipanjan Pan(Co-Founder, Chief Technical Officer)inPhilip Spinella(Co-Founder, Chief Medical Officer)inDaniel Getman(Director)Gregory Lanza(Director)
Co-investorsBioAdvanceDelaware Crossing Investor GroupMaryland TEDCONYBC VenturesOld Line Capital PartnersTEDCO+1 more
Kypha develops clinical diagnostic tests for immune system biomarkers, particularly complement activity markers, and provides solutions for real-time immune insights across therapeutic areas.
BiotechDeep TechHealthtechMedical DevicesSt. Louis, US
Nick Staten(Executive Officer)inT. Scott Glover(Executive Officer)inPaul K. Olson(Executive Officer, Director)
BoardDavid Smoller(Director)inJames D. Marselis(Director)Peter Reinecke(Director)in
Co-investorsMissouri Technology CorporationArsenalSerra Ventures
MediBeacon develops biocompatible fluorescent tracer agents detected by skin sensors for clinical diagnostic applications including kidney function assessment and gastrointestinal permeability measurement.
AI & Machine LearningBiotechHealthtechMedical DevicesSaint Louis, US
Richard Dorshow(Executive Officer, Director)inTerence Stern(Executive Officer)inSteven Hanley(Executive Officer, Director)
BoardSteven Miller(Director)David Present(Director)Cherine Plumaker(Director)
Co-investorsMissouri Technology CorporationNewlin Investment Company LLC
Omniose develops a platform for bioconjugate vaccine development using glycoconjugation technology to create vaccines against bacterial pathogens like Group B Streptococcus and Klebsiella pneumoniae.
BiotechDeep TechHealthtechMedical DevicesSt. Louis, US
Dr. Harding(Primary Founder)Mario Feldman(Founder, Scientific Founder)Viliam PavliakBenjamin Moutierin
BoardDr. SzymanskiDr. Projan
Panome Bio provides metabolomics, proteomics, and multi-omics integration workflows along with a computational platform that analyzes and integrates diverse biological data types.
AI & Machine LearningBiotechDeep TechHealthtechSaint Louis, US
Edward Weinstein(Executive Officer, Director)inTom Cohen(Executive Officer)in
BoardDavid Smoller(Director)inDeval Lashkari(Director)inAlexander Herzick(Director)inRob Capone(Director)in
Co-investorsTelegraph Hill PartnersCultivation Capital
Plastomics develops trait delivery technology for agriculture using cell biology, plant tissue culture, transformation, and molecular biology methods.
AgTechBiotechSt. Louis, US
Jeffrey Staub(Executive Officer, Director)inElizabeth Gallegos(Executive Officer)in
BoardMartha Schlicher(Executive Officer, Director)inBrian Clevinger(Director)Charles Bolten(Director)Dave Duncan(Director)
Co-investorsArgonautic VenturesCentennial InvestorsFulcrum Global CapitaliSelect FundMissouri Technology CorporationCultivation Capital+2 more
RhoDx develops cell-free DNA and RNA enrichment technologies for liquid biopsy cancer diagnostics.
BiotechDigital HealthMedical Devices
Charlie Rodi(Founder and CSO)in
SentiAR builds CommandEP, an FDA-cleared mixed-reality holographic augmented reality platform for cardiac electrophysiology that converts real-time catheter data into hands-free 3D holograms and virtual screens for electrophysiologists during procedures.
AI & Machine LearningHealthtechMedical DevicesSt. Louis, US
Jonathan Silva(Executive Officer, Director)Berk Tas(Executive Officer, Director)inJames Patrick Howard(Executive Officer)
BoardSean Churchill(Director)Warren Watson(Director)
Co-investorsMissouri Technology CorporationHarmonix FundService Provider CapitalCultivation Capital
Solis Agrosciences is an agricultural science company with a team focused on molecular sciences, plant transformation, and plant research.
AgTechBiotechFoodTechSaint Louis, US
Susan Martino-Catt(President and COO)inCharles Bolten(Director)Mary Fernandes(Executive Officer)Tom Cohen(Executive Officer, Director)inBrian Salmo(Director)
BoardDavid Smoller(Co-Founder & Director)in
Co-investorsMissouri Technology CorporationCultivation CapitalFINTOP Capital
SweetSpot provides a remote diabetes monitoring and management platform that improves data accessibility for clinicians and supports patients using diabetes technology such as CGMs and insulin pumps.
Digital HealthHealthtechMedical DevicesSaaS
Stephen Von Rump(Chief Executive Officer)inRalph Oiknine(Chief Medical Officer)Abigail Cohen(Chief Commercial Officer)inAmiad Fredman(Chief Product Officer)in
Co-investorsMissouri Technology CorporationCultivation Capital
BiotechSt. Louis, US
Ariel Muslera(Director)Ricardo Lisandro Bril(Director)Daniel Katzman(Executive Officer, Director)inBolten Charles(Director)
Valo Health applies technology and data to drug discovery, working across the technology, biotech, and healthcare fields.
AI & Machine LearningBiotechHealthtech
David Berry(Founder)in
Co-investorsAtinum Investment Co. Ltd.Flagship PioneeringHBM Healthcare InvestmentsHBM PartnersKoch Disruptive Technologies
Allotera (formerly Wugen) develops allogeneic T-cell therapies.
BiotechHealthtechMedical DevicesSt. Louis, US
Ayman Kabakibi(Executive Officer)inCherry Thomas(Executive Officer)inKumar Srinivasan(Executive Officer, Director)inKeith Vendola(Executive Officer)Daniel M Kemp(Executive Officer, Director)Matthew Cooper(Executive Officer)
Co-investorsAisling CapitalAlpha Wave GlobalRiverVest Venture PartnersAbingworthFidelity InvestmentsIntermediate Capital Group+1 more
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
Accuronix TherapeuticsArch Oncology IncConfluenceGalera
Portfolio news
latest coverage across their companiesCofactor Genomics · finsmes.com · Dec 16, 2025
Plastomics, Inc. · finsmes.com · Oct 28, 2025
Wugen · finsmes.com · Aug 28, 2025
Frequently asked questions
- How many investments has BioGenerator Ventures made?
- BioGenerator Ventures has 31 tracked investments, including 2 dated in the last 24 months.
- What stage does BioGenerator Ventures invest at?
- BioGenerator Ventures invests at the Pre-Seed, Seed, Series A, Series B stages.
- What is BioGenerator Ventures's typical check size?
- BioGenerator Ventures typically writes checks of $50K – $250K.
- What sectors does BioGenerator Ventures focus on?
- BioGenerator Ventures focuses on AgTech, Biotech, Digital Health, FoodTech, Healthtech, Medical Devices.
- Where is BioGenerator Ventures located?
- BioGenerator Ventures is headquartered in St. Louis, US.
- Does BioGenerator Ventures lead rounds?
- Yes, BioGenerator Ventures leads investment rounds.
- Who does BioGenerator Ventures co-invest with?
- BioGenerator Ventures most often shares deals with Missouri Technology Corporation, iSelect Fund, Argonautic Ventures, among 39 tracked co-investors.
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