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BioGenerator Ventures

Venture capital

St. Louis · Pre-Seed–Series B · 20 people tracked

Also known as BioGenerator

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Investment thesis

BioGenerator Ventures provides catalytic investments to life sciences companies across human health and plant/agriculture sciences, including therapeutics, diagnostics, medical devices, research tools, and healthcare. It combines funding with the BioGenerator Labs engine of company-building resources — technology, talent, proof-of-concept grants, coaching, grant training, and laboratory space — to accelerate new ventures. The firm often supports companies from pre-company licensing and formation through early financing rounds, leading initial financings, orchestrating additional investors, and running diligence processes. It is closely tied to the St. Louis innovation ecosystem and frequently spins ventures out of local academic institutions.

Source: firm website, verified Sep 20, 2026.

Stage
Pre-Seed–Series B
Check
$50K – $250K
HQ
St. Louis, Missouri, US
Leads rounds
Leads
Instruments
Equity · Grants
Founded
2003
Last 12 months
1 investment
Tracked investments
31

Team · 20 people

from the firm's website
Jim McCarter· Senior Managing Director, BioGenerator Ventures
Danny Griffin· VC Fellow & Kinimmune CSO
Grant Downes· Venture Fellowin
AJ Habicht· Event and Engagement Coordinator
Amy Gwin· VP of Marketing and Communications
Cecilia Gutierrez Perez· Associate, BioGenerator Ventures
Christy Althaber· Lab Manager
David Christenson· Executive in Residencein
Josh Schafer· Executive in Residence
Kevin Coffman· AgTech Advisor
Mark Martino· AgTech Advisor
Mike Davies· BioGenerator Labs at Helix
Richard Clark· Executive in Residence
Tom Schaefer· Agtech Advisor

Founder mafia

3 people who came through BioGenerator Ventures went on to found or lead other companies.

What they invest in

from 26 of 31 portfolio companies

Biotech ×21Healthtech ×14Medical Devices ×14AgTech ×7AI & Machine Learning ×7Deep Tech ×7Digital Health ×5Cleantech ×2

HQs:United States×21

Who they back

founder profiles across 11 portfolio companies
55%
solo founders
6 of 11 mapped founding teams
10%
repeat founders
of 10 founders with career history

Founding team size:solo founder×62 founders×33 founders×14+ founders×1

Where their founders worked beforefrom 10 founders with career history

Washington University in St. Louis ×2Washington University School of Medicine ×2

Investments · 31 tracked

founders shown can be your intro path

By year:2025 · 22024 · 22023 · 22022 · 12018 · 22017 · 12015 · 111 dated

Pairidex, Inc.pairidex.cominMay 2024✓ verified

Pairidex offers FusionMRD, a personalized digital droplet PCR (ddPCR) assay that detects and quantifies oncogenic gene fusions from a standard peripheral blood sample to monitor treatment response and minimal residual disease in gene fusion-driven blood cancers such as leukemia.

BiotechDigital HealthHealthtechMedical DevicesSt. Louis, US

Grant Challen(Co-Founder & Scientific Advisor)inAllyson Mayer(Interim COO)inAndrew Young(Founder & CSO)Paul Kortschak(CEO)in

BoardTodd Druley(Director)

Board seatCrystal Winkeler· per SEC Form D

Co-investorsiSelect Fund

Myonidcadrebioscience.com✓ verified

Cadre Bioscience partners with innovators to develop and bring new therapeutics to clinical application through drug development.

BiotechDeep TechHealthtechMedical DevicesSt. Louis, US

Bob Karr(Executive Chairman & CEO)

39N agtech district39northstl.com

39 North is an agtech innovation district that houses scientists, startups, and companies in shared facilities, anchored by Bayer Crop Science and the Danforth Plant Science Center.

AgTechBiotech

Agrageneagragene.cominMar 2023

Agragene develops Precision-Guided Sterile Insect Technology (pgSIT) marketed as KNOCKOUT™, a biocontrol product for controlling crop insect pests such as Spotted Wing Drosophila while reducing reliance on traditional insecticides.

AgTechBiotechClimate TechSan Diego, US

Bryan Witherbee(President and CEO)inTracy Ellis(Executive Officer)Clyde Shores(Executive Officer, Director)Robert Schmidt(Director)Gordon Alton(Executive Officer, Director)David Webb(Director)

Co-investorsMissouri Technology CorporationOspraie Ag Science

Benson Hill Biosystemsbensonhillbio.cominAug 2015 · $7.3M

Confluence Genetics (operating at bensonhillbio.com) is a seed innovation company that develops soybean genetics using AI-driven plant science and proprietary tools such as eMERGE Genetics and CropOS.

Durham, US

Matthew B Crisp(Executive Officer, Director)Lee Palles(Executive Officer)inNadine Carozzi(Executive Officer)Todd C Mockler(Executive Officer)Thomas Brutnell(Executive Officer)

BoardDaniel J Broderick(Director)

Co-investorsActivant CapitalAlexandriaCultivation CapitalFall Line CapitalGV (Google Ventures)iSelect Fund+7 more

Benson Hill Inc.bensonhill.comin

Benson Hill develops soybean seed varieties using plant genetics and AI-driven plant science to produce more nutritious and energy-dense soy for agriculture and food markets.

AgTechAI & Machine LearningFoodTech

Co-investorsActivant CapitalGV (Google Ventures)iSelect FundLewis & Clark VenturesManta Ray VenturesMercury Fund+3 more

bioiobioio.techin𝕏

BIOIO develops a genetics-based platform for elucidating drug mechanisms of action, combining decades of research in pharmacology with big data and automation to accelerate drug discovery and development.

AI & Machine LearningBiotechDeep TechLongevity

Dr. Peterson

Co-investorsLifespan Vision VenturesMissouri Technology CorporationquadraScope Venture Fund

Canopy Biosciencescanopybiosciences.com𝕏Dec 2017

Canopy Biosciences (Bruker Spatial Biology) develops spatial biology instruments and assays for analyzing gene expression, RNA, and proteins in tissue samples.

BiotechHealthtechMedical DevicesSaint Louis, US

EDWARD WEINSTEIN(President, Chief Executive Officer and Manager)inCRYSTAL WINKELER(Chief Operating Officer)CHARLES BOLTEN(Director)DAVID KINGSLEY(Director)

BoardDAVID SMOLLER(Director)in

Co-investorsAmpersand

Cofactor Genomicscofactorgenomics.comin𝕏Series A

Cofactor Genomics develops predictive diagnostics for cancer immunotherapy using RNA-expression models to characterize tumor microenvironments and predict patient response.

AI & Machine LearningBiotechHealthtechMedical DevicesSt. Louis, US

Dave Messina(Founder/COO)inJarret Glasscock(Founder/CTO)inJarret Glassock(Executive Officer, Director)Jon Armstrong(Director)in

BoardMatthew A. Ocko(Director)inMark Siegel(Director)in

Co-investorsArgonautic VenturesAscension VenturesDCVC (Data Collective)Fifty YearsiSelect FundJude Gomila+11 more

Cortex Innovation Communitycortexstl.orgin𝕏

Cortex is an innovation district in St.

Impact & Social GoodSt. Louis, US

CoverCresscovercress.comin𝕏

CoverCress Inc. develops agricultural products and seeds that enable farmers to convert idle winter fields into profitable crops.

AgTechCleantechClimate TechEnergyOlivette, US

Jim Hedges(CEO)in

Co-investorsFulcrum Global CapitalPrelude VenturesProlog VenturesCultivation Capital

Edison Agrosciencesedisonagrosciences.comJul 2024

Edison Agro Sciences develops bio-based synthetic rubber from sunflower crops as an alternative to petrochemical and natural rubber for industrial applications.

AgTechBiotechCleantechNew MaterialsSt. Louis, US

David Woodburn(Executive Officer, Director)inMatthew B Crisp(Executive Officer, Director)Thomas Hohn(Executive Officer, Director)inTom Christensen(Executive Officer, Director, Promoter)

BoardDan Broderick(Director)Matt Helms(Director)

Co-investorsArieal Southeast Angel Partners

Geneoscopy, Incgeneoscopy.comin𝕏

Geneoscopy develops innovative diagnostic technologies for gastrointestinal health, specifically focused on the detection of colorectal cancer.

BiotechDigital HealthHealthtechMedical DevicesSt. Louis, US

Andrew Barnell(Chief Executive Officer & Co-founder)inErica Barnell(Co-founder)in

Co-investorsDorm RoomiSelect FundMissouri Technology CorporationCultivation Capital

Immunophotonics, Inc.immunophotonics.comin

Immunophotonics is a clinical-stage biotech company developing novel treatments for solid-tumor cancers and infectious diseases by combining tumor ablation with systemic cancer immunotherapy.

BiotechDeep TechDigital HealthMedical DevicesSt. Louis, US

Dr. Hode(Co-Founder & Senior Fellow)Mr. Alleruzzo(Co-Founder & Director)Dr. Chen(Co-Founder)Dr. Robert Nordquist(Co-Founder)Luciano Alleruzzo(Director, Promoter)Wei Chen(Director, Promoter)

Co-investorsArgonautic VenturesCentennial InvestorsiSelect FundMissouri Technology CorporationCultivation Capital

KaloCytekalocyte.cominApr 2018

KaloCyte develops ErythroMer, a dried, shelf-stable artificial red blood cell for use in emergency and trauma care when stored blood is unavailable or in short supply.

BiotechDeep TechHealthtechMedical DevicesBaltimore, US

Allan Doctor(Co-Founder & CSO)inDipanjan Pan(Co-Founder, Chief Technical Officer)inPhilip Spinella(Co-Founder, Chief Medical Officer)inDaniel Getman(Director)Gregory Lanza(Director)

Co-investorsBioAdvanceDelaware Crossing Investor GroupMaryland TEDCONYBC VenturesOld Line Capital PartnersTEDCO+1 more

Kyphakypha.netin

Kypha develops clinical diagnostic tests for immune system biomarkers, particularly complement activity markers, and provides solutions for real-time immune insights across therapeutic areas.

BiotechDeep TechHealthtechMedical DevicesSt. Louis, US

Nick Staten(Executive Officer)inT. Scott Glover(Executive Officer)inPaul K. Olson(Executive Officer, Director)

BoardDavid Smoller(Director)inJames D. Marselis(Director)Peter Reinecke(Director)in

Co-investorsMissouri Technology CorporationArsenalSerra Ventures

MediBeacon Inc.medibeacon.comin𝕏

MediBeacon develops biocompatible fluorescent tracer agents detected by skin sensors for clinical diagnostic applications including kidney function assessment and gastrointestinal permeability measurement.

AI & Machine LearningBiotechHealthtechMedical DevicesSaint Louis, US

Richard Dorshow(Executive Officer, Director)inTerence Stern(Executive Officer)inSteven Hanley(Executive Officer, Director)

BoardSteven Miller(Director)David Present(Director)Cherine Plumaker(Director)

Co-investorsMissouri Technology CorporationNewlin Investment Company LLC

Omnioseomniose.comin

Omniose develops a platform for bioconjugate vaccine development using glycoconjugation technology to create vaccines against bacterial pathogens like Group B Streptococcus and Klebsiella pneumoniae.

BiotechDeep TechHealthtechMedical DevicesSt. Louis, US

Dr. Harding(Primary Founder)Mario Feldman(Founder, Scientific Founder)Viliam PavliakBenjamin Moutierin

BoardDr. SzymanskiDr. Projan

Panome Biopanomebio.cominMar 2023

Panome Bio provides metabolomics, proteomics, and multi-omics integration workflows along with a computational platform that analyzes and integrates diverse biological data types.

AI & Machine LearningBiotechDeep TechHealthtechSaint Louis, US

Edward Weinstein(Executive Officer, Director)inTom Cohen(Executive Officer)in

BoardDavid Smoller(Director)inDeval Lashkari(Director)inAlexander Herzick(Director)inRob Capone(Director)in

Co-investorsTelegraph Hill PartnersCultivation Capital

Plastomics, Inc.plastomics.cominOct 2025 · $5.8M

Plastomics develops trait delivery technology for agriculture using cell biology, plant tissue culture, transformation, and molecular biology methods.

AgTechBiotechSt. Louis, US

Jeffrey Staub(Executive Officer, Director)inElizabeth Gallegos(Executive Officer)in

BoardMartha Schlicher(Executive Officer, Director)inBrian Clevinger(Director)Charles Bolten(Director)Dave Duncan(Director)

Co-investorsArgonautic VenturesCentennial InvestorsFulcrum Global CapitaliSelect FundMissouri Technology CorporationCultivation Capital+2 more

RhoDxrhodx.comin

RhoDx develops cell-free DNA and RNA enrichment technologies for liquid biopsy cancer diagnostics.

BiotechDigital HealthMedical Devices

Charlie Rodi(Founder and CSO)in

SentiARsentiar.com

SentiAR builds CommandEP, an FDA-cleared mixed-reality holographic augmented reality platform for cardiac electrophysiology that converts real-time catheter data into hands-free 3D holograms and virtual screens for electrophysiologists during procedures.

AI & Machine LearningHealthtechMedical DevicesSt. Louis, US

Jonathan Silva(Executive Officer, Director)Berk Tas(Executive Officer, Director)inJames Patrick Howard(Executive Officer)

BoardSean Churchill(Director)Warren Watson(Director)

Co-investorsMissouri Technology CorporationHarmonix FundService Provider CapitalCultivation Capital

Solis Agrosciencessolisagrosciences.cominDec 2022

Solis Agrosciences is an agricultural science company with a team focused on molecular sciences, plant transformation, and plant research.

AgTechBiotechFoodTechSaint Louis, US

Susan Martino-Catt(President and COO)inCharles Bolten(Director)Mary Fernandes(Executive Officer)Tom Cohen(Executive Officer, Director)inBrian Salmo(Director)

BoardDavid Smoller(Co-Founder & Director)in

Co-investorsMissouri Technology CorporationCultivation CapitalFINTOP Capital

SweetSpotsweetspot.healthinSep 2025

SweetSpot provides a remote diabetes monitoring and management platform that improves data accessibility for clinicians and supports patients using diabetes technology such as CGMs and insulin pumps.

Digital HealthHealthtechMedical DevicesSaaS

Stephen Von Rump(Chief Executive Officer)inRalph Oiknine(Chief Medical Officer)Abigail Cohen(Chief Commercial Officer)inAmiad Fredman(Chief Product Officer)in

Co-investorsMissouri Technology CorporationCultivation Capital

Unleash Immuno OncolyticsinFeb 2018

BiotechSt. Louis, US

Ariel Muslera(Director)Ricardo Lisandro Bril(Director)Daniel Katzman(Executive Officer, Director)inBolten Charles(Director)

Valovalohealth.comin𝕏

Valo Health applies technology and data to drug discovery, working across the technology, biotech, and healthcare fields.

AI & Machine LearningBiotechHealthtech

David Berry(Founder)in

Co-investorsAtinum Investment Co. Ltd.Flagship PioneeringHBM Healthcare InvestmentsHBM PartnersKoch Disruptive Technologies

Wugenwugen.com

Allotera (formerly Wugen) develops allogeneic T-cell therapies.

BiotechHealthtechMedical DevicesSt. Louis, US

Ayman Kabakibi(Executive Officer)inCherry Thomas(Executive Officer)inKumar Srinivasan(Executive Officer, Director)inKeith Vendola(Executive Officer)Daniel M Kemp(Executive Officer, Director)Matthew Cooper(Executive Officer)

Co-investorsAisling CapitalAlpha Wave GlobalRiverVest Venture PartnersAbingworthFidelity InvestmentsIntermediate Capital Group+1 more

Other

Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.

Accuronix TherapeuticsArch Oncology IncConfluenceGalera

Portfolio news

latest coverage across their companies

Frequently asked questions

How many investments has BioGenerator Ventures made?
BioGenerator Ventures has 31 tracked investments, including 2 dated in the last 24 months.
What stage does BioGenerator Ventures invest at?
BioGenerator Ventures invests at the Pre-Seed, Seed, Series A, Series B stages.
What is BioGenerator Ventures's typical check size?
BioGenerator Ventures typically writes checks of $50K – $250K.
What sectors does BioGenerator Ventures focus on?
BioGenerator Ventures focuses on AgTech, Biotech, Digital Health, FoodTech, Healthtech, Medical Devices.
Where is BioGenerator Ventures located?
BioGenerator Ventures is headquartered in St. Louis, US.
Does BioGenerator Ventures lead rounds?
Yes, BioGenerator Ventures leads investment rounds.
Who does BioGenerator Ventures co-invest with?
BioGenerator Ventures most often shares deals with Missouri Technology Corporation, iSelect Fund, Argonautic Ventures, among 39 tracked co-investors.

Images

BioGenerator Ventures photo

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