Twenty Two Ventures
Actively deployingPalo Alto · Pre-Seed–Seed
Investment thesis
Twenty Two targets early-stage founders building exceptional companies, particularly those in SaaS, fintech, open source, marketplaces, and developer tools. The firm invests earlier than most, often engaging with companies before public launch. With smaller check sizes, Twenty Two can make rapid investment decisions and move efficiently, which appeals to founders focused on execution. The firm seeks magnetic, tenacious, and adaptable founders with ambitious visions who demonstrate strong product execution capabilities.
Source: firm website, verified Jul 20, 2026.
What they invest in
from 14 of 26 portfolio companiesEnterprise Software ×13SaaS ×10AI & Machine Learning ×9Developer Tools ×4Data & Infrastructure ×3Fintech ×2Marketing Tech ×2Cloud Computing ×1
HQs:United States×10Colombia×1United Kingdom×1
Investments · 26 tracked
founders shown can be your intro pathCrimson uses AI to automate document review, evidence sorting, and case file organization for litigation and arbitration teams. The platform is designed to free lawyers from tedious administrative tasks so they can focus on case strategy and advocacy.
AI & Machine LearningEnterprise SoftwareLegalTechSaaSLondon, GB
Relari builds an AI development platform called Nuvi that enables developers to define intelligent agents in plain English without prompt engineering or visual programming. The platform creates testable, verifiable AI agents designed for production deployment.
AI & Machine LearningDeveloper ToolsEnterprise SoftwareSan Francisco, US
Yi Zhang(Founder)inPasquale Antonante(Founder)inYi(Founder)Pasquale(Founder)
Open-source ELT platform that replicates data from applications, APIs, and databases to data warehouses and lakes.
Enterprise features for Bazel, the open-source build system enabling 10x faster software building and testing.
Next-generation calendar application designed for professionals and teams.
Software that integrates with existing systems to streamline credit facility management for borrowers and lenders.
Infisical is an all-in-one platform for managing application secrets, certificates, and privileged access across cloud, on-premises, and AI infrastructure, serving developer teams and organizations. The platform provides centralized storage, rotation, and auditing of credentials without requiring custom scripts or ad-hoc secret management solutions.
CybersecurityDeveloper ToolsEnterprise SoftwareSan Francisco, US
Vlad Matsiiako(Founder)inTony Dang(Founder)inMaidul Islam(Founder)in
Magic Patterns generates user interface designs that match existing product styling and enables rapid prototyping of new features. The platform serves product teams and designers who need to explore design ideas, test features with customers, and collaborate on prototypes.
Developer ToolsEnterprise SoftwareSaaSSan Francisco, US
Social platform enabling fractional ownership of investment properties.
Newton builds a unified phone system platform for dental practices, integrating AI receptionist capabilities with traditional staff workflows to replace fragmented communication tools. The platform serves dental offices looking to streamline multi-location call management and operations.
AI & Machine LearningEnterprise SoftwareHealthtechSaaSSan Francisco, US
Palette Desktop is a workspace application designed for non-engineering professionals to manage writing, research, planning, operations, and design tasks across shared folders using AI agents. It provides features like sandboxed sessions, change history, and multi-agent switching without vendor lock-in.
AI & Machine LearningEnterprise SoftwareSaaS
Palette Technology provides AI-powered native image and video generation tools for creative teams, enabling them to produce audience-ready content across formats (video, visuals, structured content) from a single source material without rebuilding assets for each output.
AI & Machine LearningCreator EconomyEnterprise SoftwareSan Francisco, US
Patterns provides an AI-powered platform for financial analysis and reporting that allows users to perform data analysis using natural language instead of traditional spreadsheets. The system uses large language models and autonomous query capabilities to enable financial professionals to conduct complex analytical work through conversational interfaces.
Data & InfrastructureEnterprise SoftwareSan Francisco, US
Platform enabling deployment of production-ready, scalable ML systems with minimal engineering effort.
Open-source product operating system providing engineers with analytics, video replays, feedback tools, feature flags, and experimentation capabilities.
Platform that connects private data sources to LLM-powered applications.
Secure B2B payments platform that automates and simplifies payables processing from invoice receipt to settlement.
Platform helping organizations streamline security questionnaires, build customer trust, and accelerate deal closure.
Smobi is an AI-powered messaging platform that enables brands to send interactive RCS (Rich Communication Services) and SMS campaigns directly to customers' phones. The platform offers drag-and-drop campaign builders, AI-powered customer service agents, product card carousels, and event booking capabilities, designed for ecommerce, customer engagement, and customer support use cases.
AI & Machine LearningEnterprise SoftwareMarketing TechSaaSNew York City, US
Kunal Puri(Founder)in
Socratix provides AI agents for fraud detection and compliance investigations at financial institutions. The platform helps community banks and credit unions investigate alerts, identify threats, and generate regulatory filings in real time.
AI & Machine LearningEnterprise SoftwareFintechSaaSSan Francisco, US
Riya Jagetia(Co-Founder & CEO)inSatya Vasanth Tumati(Co-Founder & CTO)in
Treinta is a cloud-based business management system that enables small business owners to manage sales, inventory, customers, suppliers, and employees from mobile or web. The platform serves retailers, restaurants, cafés, salons, markets, and service providers across Latin America and select other regions.
AI & Machine LearningCloud ComputingEnterprise SoftwareFuture of WorkRetail TechSaaSBogotá, CO
Voicepanel provides customer research tools to help companies understand their customers faster and more reliably than traditional research methods. The platform serves businesses across industries seeking to improve product development and customer insights.
AI & Machine LearningData & InfrastructureEnterprise SoftwareMarketing TechSaaS
John Provine(Founder)inJohnAsaDavid
Largest livestream shopping platform in the U.S. connecting buyers and sellers across categories including collectibles, fashion, and sneakers.
Procurement platform used by startups and Fortune 500 companies to power purchasing operations.
Frequently asked questions
- What stage does Twenty Two Ventures invest at?
- Twenty Two Ventures invests at the Pre-Seed, Seed stages.
- What sectors does Twenty Two Ventures focus on?
- Twenty Two Ventures focuses on B2B Marketplaces, Developer Tools, Fintech, SaaS.
- Where is Twenty Two Ventures located?
- Twenty Two Ventures is headquartered in Palo Alto, US.
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