Fundraising Fox

645 Ventures

Venture capital

New York · Pre-Seed–Series B · 21 people tracked

Also known as 645 VENTURES MANAGEMENT, LLC

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Investment thesis

645 Ventures invests in exceptional founders at the earliest stages, seeking companies that are pre-product, pre-revenue, and pre-consensus. The firm evaluates founders against four traits: purity of motivation (authentic drive to solve a problem), an earned secret (non-obvious market insight from deep expertise or contrarian research), obsessive problem-solving focus, and non-consensus thinking. Beyond capital, the firm actively supports portfolio companies through go-to-market strategy, fundraising guidance, valuation and term negotiation help, and connecting founders with advisors, distribution partners, and other key stakeholders. It concentrates on several areas of deep domain experience across the technology landscape.

Source: firm website, verified Aug 3, 2026.

Stage
Pre-Seed–Series B
Check
$1M – $5M
HQ
New York, New York, US
Leads rounds
Leads
Instruments
Equity
Founded
2013
AUM
$550M
VC funds
5
Tracked investments
129

Team · 21 people

from the firm's website & public directories
Matthew Hawes· Associatein
Michael Liu· Associate

What they invest in

from 34 of 129 portfolio companies

Enterprise Software ×17AI & Machine Learning ×16SaaS ×16Fintech ×6Consumer ×4Developer Tools ×4Healthtech ×4Marketplaces ×4

HQs:United States×28Mexico×1

Investments · 129 tracked

founders shown can be your intro path
Fiscal Notefiscalnote.comin𝕏OTC: NOTE

FiscalNote provides AI-powered software that aggregates and interprets legislative and regulatory data to help organizations track and influence policy outcomes.

AI & Machine LearningData & InfrastructureGovTechSaaS

Tim Hwang(Co-founder)Gerald Yao(Co-founder)Jonathan Chen(Co-founder)Paul Donnell(Chief Accounting Officer)Jon Slabaugh(CFO and Senior VP of Corporate Development)Richard Henderson(Executive Officer)

PartnerAaron Holiday· led

Lunchbox Technologieslunchbox.ioin𝕏✓ verified

Lunchbox is a digital commerce platform for enterprise restaurants that unifies ordering, catering, loyalty, and marketing functions.

Enterprise SoftwareFoodTechRetail TechSaaS

Nabeel Alamgir(Executive Chairman & Founder)James Walker(CEO)

Board seatNnamdi Okike· per SEC Form D

UpsideHoMjoinupside.comin✓ verified

Upside provides end-to-end housing stabilization services for individuals experiencing housing instability within healthcare settings, serving health plans, employers, and their members across Medicaid, Medicare, and employer coverage.

Enterprise SoftwareHealthtechSaaSSocialWellness & FitnessFort Lauderdale, US

Jake(CEO)inPeter Badgley(Executive Officer, Director)Jacob Rothstein(Executive Officer, Director)

Board seatAaron Holiday· per SEC Form D

Clerq Inc.SEC filingmedium confidence

New York, US

Board seatNnamdi Okike· per SEC Form D · $12M raise · filed Sep 2025

Efficient Capital Labsecaplabs.comin

ECL provides non-dilutive capital financing to SaaS and AI companies with predictable recurring revenue, enabling founders to fund growth investments and bridge to their next funding round without giving up equity.

AI & Machine LearningFintechSaaSUnknown, US

KAUSTAV DAS(Executive Officer, Director)inMANISH ARORA(Director)in

BoardSANDEEP PATIL(Director)

Board seatAaron Holiday· per SEC Form D

Mandolinmandolin.cominSEC filingmedium confidence

Mandolin provides AI agents that automate back-office workflows for specialty drug administration, including patient intake, benefits verification, prior authorizations, and revenue cycle management for infusion centers and clinical practices.

AI & Machine LearningEnterprise SoftwareHealthtech

Mike Fitzgerald(Director)Eric Tobias(Director)Mary Kay Huse(Executive Officer, Director)Scott D. Dorsey(Director)

Board seatNnamdi Okike· per SEC Form D · $12M raise · filed Jun 2021

Negotiatus Corp.SEC filingmedium confidence

New York, US

Board seatNnamdi Okike· per SEC Form D · $30M raise · filed Aug 2021

ReflexAI, Inc.SEC filingmedium confidence

New York, US

Board seatNnamdi Okike· per SEC Form D · $7M raise · filed May 2024

RentSpreerentspree.comin

RentSpree is a digital platform that simplifies the home rental process by streamlining tenant screening, applications, and rent payments for renters, agents, and landlords.

MarketplacesPropTechSaaSLos Angeles, US

Michael Lucarelli(CEO & Co-founder)Paul Sirisuphang(COO & Co-founder)Ekabutr Sirisuphang(Director)Nnamdi Okike(Director)

Board seatNnamdi Okike· per SEC Form D

Setpoint Technologies Inc.SEC filingmedium confidence

Austin, US

Michael Lam(Executive Officer, Director)Michael Dixon(Executive Officer)David Haber(Director)Danielle DePalma(Executive Officer)Benjamin Rubenstein(Executive Officer, Director)Stuart Wall(Executive Officer, Director)

Board seatNnamdi Okike· per SEC Form D · $30M raise · filed Mar 2024

SkydropXskydropx.comin𝕏

SkydropX provides shipping automation software for e-commerce and retail businesses in Mexico, handling label generation, tracking, delivery time estimation, and return management across the fulfillment process.

Enterprise SoftwareLogistics & Supply ChainMarketplacesSaaSMonterrey, MX

Tavo Zambrano(Founder/CEO)inArmando Solbes(Founder)inLuis Garza Sada(Executive Officer, Director)Weston WAMP(Director)Arnoldo Collin(Executive Officer, Director)

Board seatAaron Holiday· per SEC Form D

Uptiquptiq.aiinSEC filingmedium confidence

Uptiq develops AI agents that automate operational workflows in banking and lending, enabling credit execution, underwriting, and portfolio management without replacing existing systems.

AI & Machine LearningEnterprise SoftwareFintechMckinney, US

Ganapathi Palanipandian(Director)Snehal Fulzele(Executive Officer, Director)in

BoardMichael Walsh(Director)

Board seatNnamdi Okike· per SEC Form D · $23.6M raise · filed Feb 2025

VIVIDLY INC.SEC filingmedium confidence

Tomball, US

Board seatNnamdi Okike· per SEC Form D · $31.5M raise · filed Jan 2025

Abacus

PartnerAaron Holiday· led

Accend
Acclaim
Agency
Airfold
Alexalex.comin𝕏

Alex is a recruitment automation platform that conducts candidate screening, interviews, and scoring using standardized questions and objective criteria.

AI & Machine LearningEnterprise SoftwareHR TechSaaSSan Francisco, US

Aaron Wang(Founder)inJohn Rytel(Founder)in

Alex
Alice
All Hands AIall-hands.devin𝕏

All Hands develops OpenHands, an open-source, model-agnostic platform for building and running AI coding agents, providing the interface, automation, and control layer to scale from a single local agent to an organization-wide system.

AI & Machine LearningCloud ComputingDeveloper ToolsEnterprise Software

Robert Brennan(CEO)Graham Neubig(Chief Scientist)Xingyao Wang(Chief AI Officer)Ben Solari(CRO)

Alma Security
Amogyfastcompany.com

Healthtech

John DeLoche(Director)Riaz Valani(Director)Jeremy Alberga(Resigned as an executive officer in April 2015.)Nathan D Wolfe(Executive Officer, Director)Robert Mann(Executive Officer, Director)

Andrenaandrena.comin𝕏

Andrena is a wireless Internet service provider that delivers high-speed connectivity to multi-tenant buildings and households using wireless technology beamed to building roofs, then distributed wirelessly to units.

CleantechCloud ComputingNew Jersey, US

Neil Chatterjee(Founder)

AptDecoaptdeco.comin𝕏

AptDeco is an online marketplace where users buy and sell used furniture with integrated delivery services.

Circular EconomyConsumerE-commerceLogistics & Supply ChainMarketplacesNew York City, US

Reham Fagiri(Founder/CEO)inKalam Dennis(Founder)inBrett Topche(Director)

Apty
Arborjoinarbor.comin𝕏

Arbor provides a platform that helps households access renewable electricity at lower costs while reducing energy-related complexity.

ConsumerEnergySaaS

Aryeo
Athena Intelligence
Attention
BeFreed
BeSpoke
Besxar Space
Betterviewbetterview.comin𝕏

Betterview provides a property intelligence platform that combines high-resolution aerial imagery with AI to detect roof condition, property perils, and risk factors, and integrates 2,500+ external data points with insurers' internal policy data.

AI & Machine LearningInsurTechPropTechSan Francisco, US

PartnerAaron Holiday· led

BigEyebigeye.comin𝕏

Bigeye is a data observability platform that monitors and improves the reliability of datasets and pipelines for data engineering teams.

AI & Machine LearningData & InfrastructureDeveloper ToolsEnterprise Software

Kyle Kirwan(Co-founder)Egor Gryaznov(Co-founder)

Causelycausely.ioin𝕏

Causely builds autonomous reliability software that helps engineering teams prevent incidents and reduce troubleshooting time in cloud-native environments.

AI & Machine LearningCloud ComputingDeveloper ToolsEnterprise Software

Dr. Shmuel Kliger(Founder)

Clerq
Condor
Cotiss
Crescendo Health
Cube Dev
DeepSourcedeepsource.comin𝕏

DeepSource provides developer tools for code quality and security.

AI & Machine LearningCybersecurityDeveloper ToolsEnterprise SoftwareSaaSSan Francisco, US

Sanket Saurav(Co-founder & CEO)inJai Pradeesh(Co-founder, President)in

Diagonal
ECL
Edera
Edge
EngineEarsengineears.com𝕏

EngineEars is a platform that connects musicians with recording studios and engineers for booking and collaboration, while also providing music distribution and direct-to-fan sales tools.

B2B MarketplacesCreator EconomySaaS

Firestorm
Fly Labs

PartnerAaron Holiday· led

Forterra
General Analysis
Geniallygenially.comin𝕏

Genially is a platform for creating interactive and animated content, with built-in AI tools for content generation.

Creator EconomyEdTechSaaS

Gimlet Labs
Goldbellygoldbelly.comin𝕏

Goldbelly is an online marketplace that ships iconic foods, meals, desserts, regional specialties, and gourmet food gifts from restaurants and local shops to customers across the United States.

ConsumerE-commerceFoodTechMarketplacesNew York City, US

Joe Ariel(Founder/CEO)inJoel Gillman(Founder/Vice President of Engineering)inVanessa Torrivilla(Founder/CPO)in

PartnerAaron Holiday· led

Hallway
Hanover Park
Haplotype Labs
HockeyStack
Inner Balance

Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.

Frequently asked questions

What stage does 645 Ventures invest at?
645 Ventures invests at the Pre-Seed, Seed, Series A, Series B stages.
What is 645 Ventures's typical check size?
645 Ventures typically writes checks of $1M – $5M.
What sectors does 645 Ventures focus on?
645 Ventures focuses on AI & Machine Learning, Consumer, Data & Infrastructure, Enterprise Software, Fintech, SaaS, Sector Agnostic, Space Tech.
Where is 645 Ventures located?
645 Ventures is headquartered in New York, US.
Does 645 Ventures lead rounds?
Yes, 645 Ventures leads investment rounds.

Media · Podcasts & interviews

featuring the team

448th 1Mby1M Entrepreneurship Podcast With Nnamdi Okike, 645 Ventures

1Mby1M Roundtables · Nnamdi Okike

Nnamdi Okike on Building 645 Ventures, Bias in Fundraising, and Being a Boston Sports Fan in New ...

Something Ventured Podcast · Nnamdi Okike

Watch CNBC's full interview with 645 Ventures' Nnamdi Okike

Nnamdi Okike · cnbc.com

645 Ventures' Nnamdi Okike on investing in tech's 'behavioral change economy'

CNBC Television · Nnamdi Okike

448th 1Mby1M Roundtable June 27, 2019: With Nnamdi Okike, 645 Ventures

1Mby1M Roundtables · Nnamdi Okike

Fireside Chat: 645 Ventures Co-Founder Aaron Holiday

Aaron Holiday · vimeo.com

Co-investors · 65

Andreessen Horowitz

Andreessen Horowitz's Strategic Partnerships page describes collaborations that connect its portfolio companies with established institutions to help scale and deploy their technology.

$500K – $50M
FJ Labs

FJ Labs is a venture capital firm specializing in marketplaces and network-effect businesses, having built a large portfolio of marketplace startups with over 30 becoming unicorns.

$250K – $2M
QED Investors

QED Investors is a venture capital firm founded by former Capital One executives that invests in founders building transparency and fairness into financial services.

$30K – $25M
Costanoa Ventures

Costanoa Ventures is an early-stage venture capital firm that backs a select group of founders solving large, difficult problems, positioning itself as a long-term, operationally engaged partner from a company's earliest days through later milestones.

Both backed · 2
BigEyeVIVIDLY INC.
$500K – $8M
Rally Ventures Management, Llc

Rally Ventures is an early-stage venture capital firm focused exclusively on B2B/business technology companies, backing high-potential startups across sectors such as AI/ML, cybersecurity, fintech and SaaS.

Both backed · 2
RentSpreeNegotiatus Corp.
$100K – $4M
Chaac Ventures

Chaac Ventures is an early-stage venture firm that backs founders connected to the Princeton University tech and innovation ecosystem, leveraging that global network to help portfolio companies grow.

Both backed · 2
Fiscal NoteOvertime
$250K – $1M
Craft Ventures

Craft Ventures is a venture capital firm founded and run by former founders, operators, and investors who provide startups with hands-on support, senior talent access, and proven scaling playbooks.

Both backed · 1
$50K – $50M
Greylock Partners

Greylock Partners is a venture capital firm that backs founders at the earliest stages, often as their first investor before a product exists.

Both backed · 1
$100K – $200M
Everywhere Ventures

Everywhere Ventures is an early-stage venture firm that backs founders globally, supported by a community of founders and operators as LPs.

Both backed · 1
$250K
Spark Capital

Spark Capital is a venture capital firm that backs founders across technology and consumer companies; it notably led Twitter's Series B in 2008.

Both backed · 1
Overtime
$500K – $25M
Great Oaks Venture Capital

Great Oaks Venture Capital is a New York-based early-stage investor that partners with founders at the earliest stages of company building across the United States.

Both backed · 1
$50K – $500K
Sierra Ventures

Sierra Ventures is an early-stage venture capital firm that invests in first-principles founders, backing companies from inception through Series A across AI infrastructure, applied/vertical AI, deep tech, and physical/embodied AI.

Both backed · 1
$10M
53 more co-investors

Trinity VenturesPrimary Venture PartnersHigh AlphaOwl VenturesSilverton PartnersFlare Capital PartnersAmity VenturesEvolution Equity Partners3VCGrace Beauty CapitalPrimo VenturesCurql Collective, LLCRedpoint VenturesInsight PartnersBain Capital VenturesCRV (Charles River Ventures)Tiger Global ManagementSapphire VenturesEniac VenturesSusa VenturesOffline VenturesLiquid VenturesUpHonest CapitalFreestyle CapitalStride VCFoundry GroupDN CapitalBase10 PartnersAccompliceGaingelsLeft Lane CapitalAlleyCorpTeamworthy VenturesDecibel PartnersFlourish VenturesAnorak VenturesBaruch Future VenturesSummit PartnersEndeavor CatalystGutter Capital35VenturesVera EquityContour Venture PartnersANIMO VenturesPage One VenturesLiveOak Venture PartnersMarket One CapitalProof GroupBain Capital CryptoA*Cantos VenturesMetaplanetLearnLaunch Fund Accelerator

Firms observed investing alongside 645 Ventures, from public investor directories. Shared companies are the overlap with 645 Ventures's recorded portfolio.

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