645 Ventures
Venture capitalNew York · Pre-Seed–Series B · 21 people tracked
Also known as 645 VENTURES MANAGEMENT, LLC
Investment thesis
645 Ventures invests in exceptional founders at the earliest stages, seeking companies that are pre-product, pre-revenue, and pre-consensus. The firm evaluates founders against four traits: purity of motivation (authentic drive to solve a problem), an earned secret (non-obvious market insight from deep expertise or contrarian research), obsessive problem-solving focus, and non-consensus thinking. Beyond capital, the firm actively supports portfolio companies through go-to-market strategy, fundraising guidance, valuation and term negotiation help, and connecting founders with advisors, distribution partners, and other key stakeholders. It concentrates on several areas of deep domain experience across the technology landscape.
Source: firm website, verified Aug 3, 2026.
Team · 21 people
from the firm's website & public directoriesWhat they invest in
from 34 of 129 portfolio companiesEnterprise Software ×17AI & Machine Learning ×16SaaS ×16Fintech ×6Consumer ×4Developer Tools ×4Healthtech ×4Marketplaces ×4
HQs:United States×28Mexico×1
Investments · 129 tracked
founders shown can be your intro pathFiscalNote provides AI-powered software that aggregates and interprets legislative and regulatory data to help organizations track and influence policy outcomes.
AI & Machine LearningData & InfrastructureGovTechSaaS
Tim Hwang(Co-founder)Gerald Yao(Co-founder)Jonathan Chen(Co-founder)Paul Donnell(Chief Accounting Officer)Jon Slabaugh(CFO and Senior VP of Corporate Development)Richard Henderson(Executive Officer)
PartnerAaron Holiday· led
Lunchbox is a digital commerce platform for enterprise restaurants that unifies ordering, catering, loyalty, and marketing functions.
Enterprise SoftwareFoodTechRetail TechSaaS
Nabeel Alamgir(Executive Chairman & Founder)James Walker(CEO)
Board seatNnamdi Okike· per SEC Form D
Upside provides end-to-end housing stabilization services for individuals experiencing housing instability within healthcare settings, serving health plans, employers, and their members across Medicaid, Medicare, and employer coverage.
Enterprise SoftwareHealthtechSaaSSocialWellness & FitnessFort Lauderdale, US
Jake(CEO)inPeter Badgley(Executive Officer, Director)Jacob Rothstein(Executive Officer, Director)
Board seatAaron Holiday· per SEC Form D
New York, US
Board seatNnamdi Okike· per SEC Form D · $12M raise · filed Sep 2025
ECL provides non-dilutive capital financing to SaaS and AI companies with predictable recurring revenue, enabling founders to fund growth investments and bridge to their next funding round without giving up equity.
AI & Machine LearningFintechSaaSUnknown, US
KAUSTAV DAS(Executive Officer, Director)inMANISH ARORA(Director)in
BoardSANDEEP PATIL(Director)
Board seatAaron Holiday· per SEC Form D
Mandolin provides AI agents that automate back-office workflows for specialty drug administration, including patient intake, benefits verification, prior authorizations, and revenue cycle management for infusion centers and clinical practices.
AI & Machine LearningEnterprise SoftwareHealthtech
Mike Fitzgerald(Director)Eric Tobias(Director)Mary Kay Huse(Executive Officer, Director)Scott D. Dorsey(Director)
Board seatNnamdi Okike· per SEC Form D · $12M raise · filed Jun 2021
New York, US
Board seatNnamdi Okike· per SEC Form D · $30M raise · filed Aug 2021
New York, US
Board seatNnamdi Okike· per SEC Form D · $7M raise · filed May 2024
RentSpree is a digital platform that simplifies the home rental process by streamlining tenant screening, applications, and rent payments for renters, agents, and landlords.
MarketplacesPropTechSaaSLos Angeles, US
Michael Lucarelli(CEO & Co-founder)Paul Sirisuphang(COO & Co-founder)Ekabutr Sirisuphang(Director)Nnamdi Okike(Director)
Board seatNnamdi Okike· per SEC Form D
Austin, US
Michael Lam(Executive Officer, Director)Michael Dixon(Executive Officer)David Haber(Director)Danielle DePalma(Executive Officer)Benjamin Rubenstein(Executive Officer, Director)Stuart Wall(Executive Officer, Director)
Board seatNnamdi Okike· per SEC Form D · $30M raise · filed Mar 2024
SkydropX provides shipping automation software for e-commerce and retail businesses in Mexico, handling label generation, tracking, delivery time estimation, and return management across the fulfillment process.
Enterprise SoftwareLogistics & Supply ChainMarketplacesSaaSMonterrey, MX
Tavo Zambrano(Founder/CEO)inArmando Solbes(Founder)inLuis Garza Sada(Executive Officer, Director)Weston WAMP(Director)Arnoldo Collin(Executive Officer, Director)
Board seatAaron Holiday· per SEC Form D
Uptiq develops AI agents that automate operational workflows in banking and lending, enabling credit execution, underwriting, and portfolio management without replacing existing systems.
AI & Machine LearningEnterprise SoftwareFintechMckinney, US
Ganapathi Palanipandian(Director)Snehal Fulzele(Executive Officer, Director)in
BoardMichael Walsh(Director)
Board seatNnamdi Okike· per SEC Form D · $23.6M raise · filed Feb 2025
Tomball, US
Board seatNnamdi Okike· per SEC Form D · $31.5M raise · filed Jan 2025
PartnerAaron Holiday· led
All Hands develops OpenHands, an open-source, model-agnostic platform for building and running AI coding agents, providing the interface, automation, and control layer to scale from a single local agent to an organization-wide system.
AI & Machine LearningCloud ComputingDeveloper ToolsEnterprise Software
Robert Brennan(CEO)Graham Neubig(Chief Scientist)Xingyao Wang(Chief AI Officer)Ben Solari(CRO)
Healthtech
John DeLoche(Director)Riaz Valani(Director)Jeremy Alberga(Resigned as an executive officer in April 2015.)Nathan D Wolfe(Executive Officer, Director)Robert Mann(Executive Officer, Director)
Betterview provides a property intelligence platform that combines high-resolution aerial imagery with AI to detect roof condition, property perils, and risk factors, and integrates 2,500+ external data points with insurers' internal policy data.
AI & Machine LearningInsurTechPropTechSan Francisco, US
PartnerAaron Holiday· led
DeepSource provides developer tools for code quality and security.
AI & Machine LearningCybersecurityDeveloper ToolsEnterprise SoftwareSaaSSan Francisco, US
Sanket Saurav(Co-founder & CEO)inJai Pradeesh(Co-founder, President)in
EngineEars is a platform that connects musicians with recording studios and engineers for booking and collaboration, while also providing music distribution and direct-to-fan sales tools.
B2B MarketplacesCreator EconomySaaS
PartnerAaron Holiday· led
Goldbelly is an online marketplace that ships iconic foods, meals, desserts, regional specialties, and gourmet food gifts from restaurants and local shops to customers across the United States.
ConsumerE-commerceFoodTechMarketplacesNew York City, US
Joe Ariel(Founder/CEO)inJoel Gillman(Founder/Vice President of Engineering)inVanessa Torrivilla(Founder/CPO)in
PartnerAaron Holiday· led
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.
Frequently asked questions
- What stage does 645 Ventures invest at?
- 645 Ventures invests at the Pre-Seed, Seed, Series A, Series B stages.
- What is 645 Ventures's typical check size?
- 645 Ventures typically writes checks of $1M – $5M.
- What sectors does 645 Ventures focus on?
- 645 Ventures focuses on AI & Machine Learning, Consumer, Data & Infrastructure, Enterprise Software, Fintech, SaaS, Sector Agnostic, Space Tech.
- Where is 645 Ventures located?
- 645 Ventures is headquartered in New York, US.
- Does 645 Ventures lead rounds?
- Yes, 645 Ventures leads investment rounds.
Media · Podcasts & interviews
featuring the team448th 1Mby1M Entrepreneurship Podcast With Nnamdi Okike, 645 Ventures
1Mby1M Roundtables · Nnamdi Okike
Nnamdi Okike on Building 645 Ventures, Bias in Fundraising, and Being a Boston Sports Fan in New ...
Something Ventured Podcast · Nnamdi Okike
Watch CNBC's full interview with 645 Ventures' Nnamdi Okike
Nnamdi Okike · cnbc.com
645 Ventures' Nnamdi Okike on investing in tech's 'behavioral change economy'
CNBC Television · Nnamdi Okike
448th 1Mby1M Roundtable June 27, 2019: With Nnamdi Okike, 645 Ventures
1Mby1M Roundtables · Nnamdi Okike
Fireside Chat: 645 Ventures Co-Founder Aaron Holiday
Aaron Holiday · vimeo.com
Co-investors · 65
Andreessen Horowitz's Strategic Partnerships page describes collaborations that connect its portfolio companies with established institutions to help scale and deploy their technology.
FJ Labs is a venture capital firm specializing in marketplaces and network-effect businesses, having built a large portfolio of marketplace startups with over 30 becoming unicorns.
QED Investors is a venture capital firm founded by former Capital One executives that invests in founders building transparency and fairness into financial services.
Costanoa Ventures is an early-stage venture capital firm that backs a select group of founders solving large, difficult problems, positioning itself as a long-term, operationally engaged partner from a company's earliest days through later milestones.
Rally Ventures is an early-stage venture capital firm focused exclusively on B2B/business technology companies, backing high-potential startups across sectors such as AI/ML, cybersecurity, fintech and SaaS.
Chaac Ventures is an early-stage venture firm that backs founders connected to the Princeton University tech and innovation ecosystem, leveraging that global network to help portfolio companies grow.
Craft Ventures is a venture capital firm founded and run by former founders, operators, and investors who provide startups with hands-on support, senior talent access, and proven scaling playbooks.
Greylock Partners is a venture capital firm that backs founders at the earliest stages, often as their first investor before a product exists.
Everywhere Ventures is an early-stage venture firm that backs founders globally, supported by a community of founders and operators as LPs.
Spark Capital is a venture capital firm that backs founders across technology and consumer companies; it notably led Twitter's Series B in 2008.
Great Oaks Venture Capital is a New York-based early-stage investor that partners with founders at the earliest stages of company building across the United States.
Sierra Ventures is an early-stage venture capital firm that invests in first-principles founders, backing companies from inception through Series A across AI infrastructure, applied/vertical AI, deep tech, and physical/embodied AI.
▶53 more co-investors
Trinity VenturesPrimary Venture PartnersHigh AlphaOwl VenturesSilverton PartnersFlare Capital PartnersAmity VenturesEvolution Equity Partners3VCGrace Beauty CapitalPrimo VenturesCurql Collective, LLCRedpoint VenturesInsight PartnersBain Capital VenturesCRV (Charles River Ventures)Tiger Global ManagementSapphire VenturesEniac VenturesSusa VenturesOffline VenturesLiquid VenturesUpHonest CapitalFreestyle CapitalStride VCFoundry GroupDN CapitalBase10 PartnersAccompliceGaingelsLeft Lane CapitalAlleyCorpTeamworthy VenturesDecibel PartnersFlourish VenturesAnorak VenturesBaruch Future VenturesSummit PartnersEndeavor CatalystGutter Capital35VenturesVera EquityContour Venture PartnersANIMO VenturesPage One VenturesLiveOak Venture PartnersMarket One CapitalProof GroupBain Capital CryptoA*Cantos VenturesMetaplanetLearnLaunch Fund Accelerator
Firms observed investing alongside 645 Ventures, from public investor directories. Shared companies are the overlap with 645 Ventures's recorded portfolio.
Similar investors
Khosla Ventures is a venture capital firm known for backing bold, contrarian bets in world-class teams that can reshape entire industries.
OMERS Ventures is the venture capital arm of the OMERS pension plan, investing in early-stage technology founders building solutions across North America and Europe.
Callapina Capital is an operator-led, conviction-led venture firm focused on backing Indian-origin founders building category-defining companies across the US-India corridor. It has invested for over a decade with a Fund I portfolio and is now raising Fund II.
Primo Ventures is a venture capital firm that invests in early-stage companies. The firm is led by founders with prior entrepreneurial experience.
Ventech China is a venture capital firm founded in 2006 and headquartered in Shanghai, focused on early-stage investments in the internet sector.




%2520Hess.png)






























