DYDX Capital
Venture capitalRedwood City · Pre-Seed–Seed · 10 people tracked
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Investment thesis
DYDX Capital invests around the idea that venture returns depend on maximizing the rate of value creation, which it frames through the calculus concept of derivatives (change in value, DY, over time, DX). The firm believes breakthrough products emerge from the ability to capture, analyze, and iterate on data, and that solving complex optimization problems requires large, high-quality data sets. It sees a 'Data SuperCycle' — a new era of data capture and analysis — accelerating solutions to large, expensive problems across verticals including hi-tech, software security, healthcare, and industrial, often transcending the sector where they first appear.
Source: firm website, verified Aug 3, 2026.
Team · 10 people
from the firm's website & public directoriesFounder mafia
2 people who came through DYDX Capital went on to found or lead other companies.
What they invest in
from 20 of 23 portfolio companiesAI & Machine Learning ×11AgTech ×8Biotech ×7Deep Tech ×7FoodTech ×7SaaS ×5Data & Infrastructure ×3Enterprise Software ×2
HQs:United States×11New Zealand×2India×1
Who they back
founder profiles across 17 portfolio companiesFounding team size:solo founder×82 founders×53 founders×4
Where their founders studiedfrom 16 founders with education data
Stanford University Graduate School of Business ×3Brigham Young University ×2University of Wisconsin-Madison ×2Wisconsin School of Business ×2
What their founders studiedfrom 18 founders with field-of-study data
Engineering ×5Business & Management ×4Life Sciences ×4Economics ×3Chemistry ×2Finance & Accounting ×2Humanities ×2
Where their founders worked beforefrom 16 founders with career history
Anterra Capital ×2McKinsey & Company ×2University of New Mexico ×2
Accelerator rootsportfolio companies that came through a program
Investments · 23 tracked
founders shown can be your intro pathBy year:2026 · 12025 · 22023 · 12021 · 12016 · 12015 · 17 dated
Sprout is New Zealand's early-stage startup accelerator and investor focused on agrifood innovation, providing funding, mentorship, and industry connections to entrepreneurs scaling technologies that improve food systems sustainability.
AgTechCloud ComputingDeep TechFoodTechImpact & Social GoodSaaSNew Zealand, NZ
Co-investorsOurCrowd
Uses UV light signals to boost seed and seedling genetic potential; domiciled in the USA.
Palmerston North
Jason Wargent(Executive Officer)inSteven Sibulkin(Executive Officer, Director)Mark Brown(Director)Mary Dimou(Director)John Bedbrook(Director)Kirsty Bellringer(Director)
Board seatDean TilyardAdrian Percy· per SEC Form D · $1.3M raise · filed Dec 2021
Co-investorsAngel HQArc AngelsAzolla VenturesBooster Innovation FundEnterprise AngelsIcehouse Ventures+5 more
Animol is a biopharmaceutical company developing a proprietary pipeline of novel veterinary small-molecule drugs for both companion and farm animals, targeting areas from anti-parasitics to chronic diseases.
AgTechAI & Machine LearningBiotechDeep TechHealthtechBoston, US
Andrew Calabrese(Scientific Co-Founder)inAndrew Calabrese, Ph.D.(Scientific Co-Founder)Douglas E. Hutchens(CSO)inLogan Andrews(Head of Program Management)inPhilip Austin(Managing Partner, Anterra Capital; co-founder of Animol)inAndrew Plant(Executive Officer, Director)in
Co-investorsNovalis LifeSciencesAnterra Capital
Berkeley Yeast develops genetically engineered yeast strains for the fermented beverages industry, offering improved flavor control, scalability, and consistency while reducing resource and energy consumption.
AgTechBiotechFoodTechBerkeley, US
Charles Denby(Founder)inPhilip Austin(Director)
Co-investorsCollaborative FundAnterra CapitalRefactor Capital
AI Engine for Complex After-Market Service
Co-investorsArka Venture LabsMoment Ventures, LlcPrana Tech VenturesNivesha Ventures
Cime Therapeutics is developing a chemistry-first drug discovery platform that combines automation, AI/ML, and synthetic chemistry to make molecules faster and more cost-effectively.
AI & Machine LearningBiotechDeep TechDenver, US
James Brewster(Chief Executive Officer)inJames Thomas Brewster II(Executive Officer, Director)
BoardChris Erickson(Director)in
Co-investorsRange VCService Provider Capital
Citrine provides an AI platform for product development used across organizations, with expertise in materials discovery and advanced manufacturing optimization.
Advanced ManufacturingAI & Machine LearningDeep TechEnterprise SoftwareNew MaterialsRedwood City, US
Greg Mulholland(Co-founder & CEO)inBryce Meredig(Executive Officer, Director)inRahim Lakhani(Executive Officer)in
BoardScott Brady(Director)inMark Cupta(Director)inAmar Hanspal(Director)
Co-investorsAlumni VenturesB&C Innovation InvestmentsCm VentureDCVC (Data Collective)Endeavor8Isai+8 more
ClimateAi offers ClimateLens, an AI and machine-learning platform that applies patented models to weather and climate data at 1km resolution to produce short- and long-term forecasts and actionable insights.
AgTechAI & Machine LearningClimate TechSan Francisco, US
Himanshu Gupta(Founder)in
Co-investorsACADEMY INVESTORAIN VenturesBlackhorn VenturesClimacticNeotribe VenturesNo Talking Capital+3 more
Drip provides trade financing and working capital solutions for small and midsize businesses conducting cross-border commerce, using automated underwriting and transaction processing to assess credit and connect borrowers with capital providers and logistics partners.
FintechMH, IN
Pushkar Mukewar(CEO)inNeil Kothari(CEO)Yash Kothari(New Business Development)inNaqiyah Sohagpurwalla(Recruiter)Chanchal Singh(HR Lead)
Co-investorsAccelBetter Tomorrow VenturesBragiel BrothersEndeavor8GMO VenturePartnersIncubate Fund+19 more
Enko discovers and develops novel crop protection products for farmers using a proprietary AI and machine learning discovery platform to combat pests and diseases.
AgTechAI & Machine LearningBiotechBoston, US
Jacqueline Heard(Executive Officer, Director)inTom Meade(Chief Science Officer)Philip Austin(Director)inSteffen Helmling(Director)Anthony Klemm(CEO and Board Director)
Co-investorsAlumni VenturesCastor VenturesConnecticut InnovationsEndeavor8Germin8 VenturesNovalis LifeSciences+5 more
Good Eggs is an online grocery service that delivers fresh produce, groceries, and food products to consumers.
Direct to ConsumerE-commerceFoodTechMarketplacesOakland, US
Alon Salant(Founder)inRob Spiro(Founder)inGeorgina Bale(Co-founder)Bentley Hall(Former Chief Executive Officer)inKeith Brewer(Chief Executive Officer)Rodrigo Arevalo(Former Chief Executive Officer)in
Co-investorsBaseline VenturesCollaborative FundCorrelation VenturesDns CapitalFinistere VenturesGlade Brook Capital Partners+14 more
Immuto Scientific uses patient-derived tissue models combined with computational structural proteomics and machine learning to identify disease-specific protein targets for drug discovery.
AI & Machine LearningBiotechDeep Tech
Faraz A Choudhury(CEO & Founder)inDaniel Benjamin(Co-Founder & CTO)in
Co-investorsGreat Oaks Venture CapitalTundra AngelsVenture ManagementWisconsin Investment Partners
MarketDial provides a testing platform that combines machine learning with human expertise to help companies conduct in-store experiments and make data-driven decisions.
AI & Machine LearningData & InfrastructureRetail TechSaaSSalt Lake City, US
Morgan Davis(Founder)inJohnny Stoddard(Founder)inJohn Pisceta(Founder)
BoardBen Capell(Director)inDavid Silverman(Director)in
Co-investorsCrosslink CapitalEndeavor8EPIC VENTURESKickstartPeterson VenturesBlumberg Capital+3 more
Matterworks builds foundation models (its Large Spectral Model, delivered via the cloud-based Pyxis platform) that analyze biochemical omics and mass spectrometry data to make predictions for life science R&D.
AI & Machine LearningBiotechDeep TechHealthtech
Jack (J.M.) Geremia(Founder)inEric Carlson, PhD
BoardTony KulesainMichael Lavinin
Co-investorsGermin8 VenturesiGlobe PartnersIntermountain HealthOMX VenturesPillar VCWing+1 more
Plenty builds controlled environment farms that use vertical growing methods to produce food using significantly less land and water than conventional agriculture.
AgTechFoodTechVirginia, US
Mary S Moore(Executive Officer, Director)David Hughes Sommers(Executive Officer)Matt Barnard(Founder)Nate Storey(Founder)
Co-investorsDCM VenturesNFXSoftBank Vision FundBezos ExpeditionsDCMFinistere Ventures+3 more
ProducePay operates a Predictable Commerce Platform for the fresh produce industry, connecting growers and buyers while providing capital, trading opportunities, supply chain visibility, and market insights.
AgTechFintechFoodTech
Pablo Borquez(Founder & CEO)inBen DusastreinPablo Borquez Schwarzbeckin
Co-investors500 GlobalArena VenturesAstanor VenturesDorm RoomEndeavor8FJ Labs+15 more
Scentian Bio combines synthetic biology and AI to develop biosensors based on synthesized insect odorant receptors, creating a digital sense of smell and taste that can detect and measure the concentration of thousands of compounds.
AI & Machine LearningBiotechDeep Tech
Andrew Králíček(Founder & Chief Technology Officer)inJonathan Good(Chief Executive Officer)inColm Carraher(Chief Scientific Officer)inNikki Lorigan(Chief Financial Officer)
Co-investorsBooster Innovation FundSproutFinistere VenturesIcehouse VenturesOurCrowdToyota Ventures
Sidework makes automated beverage dispensers for food service establishments that can mix a wide variety of drinks with customizable ingredients and add-ons.
FoodTechHardwareRetail TechRoboticsSaaS
Brian Kaplan(Founder)in
Co-investorsHumba VenturesWinklevoss CapitalCherubic VenturesFinistere VenturesOutlander VCPathbreaker Ventures+1 more
TESS is an autonomous AI agents platform that orchestrates 250+ AI models to plan and execute complex professional tasks end-to-end, such as building presentations, dashboards, spreadsheets, reports, and market research.
AI & Machine LearningFuture of WorkSaaS
Co-investorsHoneystone Ventures
The Climate Corporation offers FieldView, a digital agriculture platform that connects with 60+ partners to make farm data sharing and season planning easier for growers.
AgTechData & InfrastructureSaaS
David Friedberg(Founder)Siraj Khaliq(Founder)
Co-investorsACADEMY INVESTORAnthemis VentureFelicis VenturesFirst Round CapitalGlynn Capital ManagementGV (Google Ventures)+8 more
Tovala provides prepared meals delivered weekly that are cooked in a proprietary WiFi-connected smart oven, requiring minimal preparation and cooking time.
ConsumerFoodTechHardwareIoTChicago, US
David Rabie(CEO)inBryan Wilcox(CTO)Adam Brakhane(Director, Software)Keeley Kabala(Vice President Engineering)Neel Bhat(Backend Developer)Lauren Funk(Vice President of Marketing)
Co-investorsBeringeaCaruso VenturesComcast VenturesEvolution VC PartnersFJ LabsGFR Fund+24 more
Tribal provides a metadata fabric that lets business teams build and deploy enterprise-native AI agents and applications inside existing systems of record like Salesforce and NetSuite.
AI & Machine LearningData & InfrastructureEnterprise Software
Co-investorsTeam8 Capital
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
Citrene
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.
Portfolio news
latest coverage across their companiesMatterworks · finsmes.com · Jun 3, 2025
Frequently asked questions
- How many investments has DYDX Capital made?
- DYDX Capital has 23 tracked investments, 2 of which have exited, including 3 dated in the last 24 months.
- What stage does DYDX Capital invest at?
- DYDX Capital invests at the Pre-Seed, Seed stages.
- What sectors does DYDX Capital focus on?
- DYDX Capital focuses on AI & Machine Learning, Biotech, Cybersecurity, Data & Infrastructure, Deep Tech, Enterprise Software, Fintech, Healthtech, New Materials, SaaS.
- Where is DYDX Capital located?
- DYDX Capital is headquartered in Redwood City, US.
- Does DYDX Capital lead rounds?
- Yes, DYDX Capital leads investment rounds.
- Who does DYDX Capital co-invest with?
- DYDX Capital most often shares deals with Endeavor8, Collaborative Fund, FJ Labs, among 113 tracked co-investors.
Images
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