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Waterline Ventures

Venture capital

Cambridge · Growth · 14 people tracked

Also known as WATERLINE VENTURES, LLC

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Investment thesis

Waterline Ventures concentrates exclusively on healthcare, investing in early-growth technology and service-enabled technology companies in that sector. The firm believes success in healthcare demands deep domain expertise built on extensive industry experience, and it maintains a disciplined single-market focus. It emphasizes building lifetime relationships with entrepreneurs, aiming to back founders across multiple ventures throughout their careers. Waterline also stresses capital efficiency, working with founders to craft financing plans appropriate to each company's needs rather than assuming every idea requires large amounts of capital. Drawing on decades of investing and operating experience, the firm supports founders through its network while letting them run their businesses.

Source: firm website, verified Sep 29, 2026.

Stage
Growth
HQ
Cambridge, Massachusetts, US
Instruments
Equity
Founded
2014
Last 12 months
1 investment
Private fund assets
$256.9M
VC funds
5
Tracked investments
45
Acquisitions
4

Team · 14 people

from the firm's website & curated & public directories

What they invest in

from 32 of 45 portfolio companies

Healthtech ×28Digital Health ×18SaaS ×13AI & Machine Learning ×8Enterprise Software ×7Medical Devices ×5Cloud Computing ×3InsurTech ×3

HQs:United States×27Canada×1

Who they back

founder profiles across 19 portfolio companies
68%
solo founders
13 of 19 mapped founding teams
44%
repeat founders
of 16 founders with career history
~3 yrs
old at investment
median across 12 dated deals

Founding team size:solo founder×132 founders×43 founders×14+ founders×1

Where their founders studiedfrom 16 founders with education data

Harvard University ×3UMN Carlson School of Management ×3Harvard T.H. Chan School of Public Health ×2

What their founders studiedfrom 15 founders with field-of-study data

Business & Management ×5Finance & Accounting ×3Economics ×2Engineering ×2Medicine ×2

Where their founders worked beforefrom 16 founders with career history

World Economic Forum ×3Harvard Business School ×2World Health Organization ×2

Investments · 45 tracked

founders shown can be your intro path

By year:2026 · 12025 · 32023 · 22022 · 22021 · 22020 · 32019 · 12018 · 22016 · 12015 · 12012 · 119 dated

SAGE SCIENCE, INC.sagescience.cominApr 2016SEC filingmedium confidence

Advanced ManufacturingBeverly, US

Michael Finney(Director)inJonathan Lourie(Executive Officer)Todd Barbera(Executive Officer, Director)in

BoardJohn D Curtin(Director)inBernard M Gordon(Director)Gary P Magnant(Director)

Board seatJohn Curtin· per SEC Form D · $2M raise · filed Apr 2016

Co-investorsICV Venture Engineering

Ambient Clinical Analyticsambientclinical.com

Ambient Clinical develops Sepsis DART, a clinical monitoring platform that integrates with Epic, Cerner, and Meditech to identify sepsis patients and track SEP-1 bundle compliance in real time across care transitions.

HealthtechMedical DevicesSaaSRochester, US

Allen J. Berning(Executive Officer, Director, Promoter)Tim Kuebelbeck(Executive Officer)

BoardGreg Lea(Director)Brian Pickering(Director)

Co-investorsDakota Venture GroupMairs & Power VCSoutheast Minnesota Capital Fund

Amwellamwell.com

Telemedicine services for health systems, health plans, employers, and physicians

Phyllis Gotlibin

Co-investorsAllianz XLG Technology VenturesMcKesson VenturesP5 Health VenturesPerot JainWestway Capital+1 more

Anagramgoanagram.com

Anagram provides insurance administration and revenue cycle management software and billing services for eye care practices, covering eligibility and benefits verification, claim submission and scrubbing, denial management, and payment reconciliation across both vision and medical insurance.

HealthtechInsurTechSaaS

Co-investorsFundersClubBlackstone Life SciencesHealthy VenturesKEC VenturesKickstartNextView Ventures

Anagramanagram.care𝕏

Anagram builds software to help eye care providers manage vision insurance, lab ordering, and administrative workflows so they can deliver better patient care affordably.

Enterprise SoftwareHealthtechInsurTechSaaS

Austin Winfield(Founder)in

Co-investorsGreatPoint VenturesHealthy VenturesManchesterStory Group, LLCBlackstone Life SciencesKEC VenturesKickstart+1 more

Anagramanagram.xyz

Anagram describes itself as an institution focused on crypto and the "ownership economy," offering staking services and deploying human and financial capital in the space.

Crypto & Web3

Austin Winfield(Founder)in

Co-investorsMarin Digital VenturesBlackstone Life SciencesHealthy VenturesKEC VenturesKickstartNextView Ventures

Andgoandgosystems.comSep 2022 · $5.6M

Andgo provides intelligent automation software for absence management and shift filling, handling workflows like shift bidding, sick-call intake, and vacation scheduling.

HealthtechHR TechSaaSSaskatoon, CA

Tom Ross(Chief Executive Officer)inErik Frederiksen(Chief Technology Officer)in

Co-investorsFirst Ascent Ventures

Aviziaavizia.cominAcquired

Avizia provides a digital care platform integrating technology, services, and devices to support care delivery across in-person, virtual, and automated settings for providers, payers, and patients.

Cloud ComputingDigital HealthEnterprise SoftwareHealthtechBoston, US

Michael Baird(Executive Officer, Director)Ido SchoenberginRoy SchoenberginPhyllis GotlibinSteven Luke Leininger(Executive Officer, Director)Corey Costley(Executive Officer)

Co-investorsMartin VenturesNextGen Venture PartnersBlu Venture InvestorsBlue Delta CapitalHealthQuest CapitalLavrock Ventures+1 more

Bright HealthCarebrighthealthcare.com

Bright HealthCare was a health insurance provider that offered Individual and Family (ACA), Medicare Advantage, and Small Group plans in the United States.

HealthtechInsurTechMinneapolis, US

Co-investorsCross Creek Advisors

Carta Healthcarecarta.healthcareinJun 2023

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AI & Machine LearningDigital HealthHealthtechPittsburgh, US

Gilan El Saadawi(Executive Officer, Director, Promoter)Betsy Castillo(Head of Clinical Data Abstraction)inMichael Finke(Director)Brenton Burns(Director)Scot Stevens(Director)Aaron Brauser(Executive Officer, Director, Promoter)

Co-investorsAsset Management CompanyCU Healthcare Innovation FundFrist Cressey VenturesHealthy VenturesKatalyst VenturesKatalyst.Ventures+10 more

Common Sensingcommon-sensing.comin𝕏Apr 2018 · $6.6M

HealthtechCambridge, US

Richard Whalley(Executive Officer, Director)James White(Executive Officer, Director)

BoardPatrick Flynn(Director)

Co-investorsSanofi VenturesQualcomm Ventures

Comprehensivecomprehensive.ioin𝕏Feb 2025 · $4M

Comprehensive provides AI-powered compensation analytics and benchmarking software for managing employee pay, equity, and pay equity analysis.

AI & Machine LearningHR TechSaaSSan Francisco, US

Roger Lee(Executive Officer, Director, Promoter)inTeddy Sherrill(Executive Officer, Director, Promoter)in

Co-investorsFloodgateInspired CapitalJude GomilaSoma Capital8VCAccess Industries+14 more

Curedcured.healthin𝕏Sep 2019acquired by Innovaccer · Jan 2024

Cured builds cloud-based enterprise software for healthcare organizations to modernize operations and improve patient and employee experiences.

AI & Machine LearningCloud ComputingDigital HealthEnterprise SoftwareHealthtechMarketing TechSan Francisco, US

Rohit(Co-Founder and Chief Customer Officer)inAshmer Aslam(Executive Officer, Director)inAndrew Sawyer(Executive Officer, Director)in

Co-investorsCU Healthcare Innovation FundHeadwater VenturesHigh AlphaMatchstick VenturesDNA Capital

evolvedMDevolvedmd.comin𝕏

evolvedMD integrates behavioral health services into primary care settings to improve access to mental health treatment.

Digital HealthHealthtechMental HealthPhoenix, US

Erik Osland(Founder)inSteve Biljan(Founder)in

BoardRobert Greenglass(Director)inCarey Lai(Director)inJason Slocum(Director)

Co-investorsConductive VenturesFCA Venture PartnersTectonic VenturesFCA Health Innovations QP

Genoa Healthcaregenoahealthcare.comin

Genoa Healthcare operates full-service pharmacies located inside mental health and community clinics, offering medication management for people with complex needs.

Digital HealthHealthtechMedical DevicesMental HealthWellness & Fitness

Co-investorsAdvent InternationalAsset Management CompanyBPOCShumway CapitalWonder VenturesiSeed Ventures+1 more

Haletryhale.comJan 2020

Nicotine addiction treatment through automatic, gradual substance weaning

Baltimore, US

Taha Shipchandler(Director)Chip Andrews(Director)Patrick Byrne(Executive Officer, Director)Clayton Andrews(Executive Officer, Director)

Co-investorsAtland VenturesBackstage CapitalChaos VenturesMonozukuri VenturesThe Venture CollectiveVento+1 more

HEALTH IPASShealthipass.comin𝕏Sep 2015

Health iPASS is a patient engagement platform for healthcare providers that integrates with practice management (PM) and EHR systems to handle pre-visit communication, digital intake, eligibility verification, AI-powered self-scheduling, and automated payment collection.

Digital HealthEnterprise SoftwareHealthtechSaaSNaperville, US

Rajesh Voddiraju(Executive Officer, Director, Promoter)inThirumal Nellutla(Director, Promoter)

Co-investorsFCA Venture PartnersHealthX VenturesHealthy Ventures

Health Rhythmshealthrhythms.cominJan 2021

Real-time objective behavioral health monitoring

HealthtechLong Island City, US

Mark Mathews(Director)Paul Gilbert(Executive Officer, Director)

Co-investorsCU Healthcare Innovation FundInformed Ventures Advisors, LlcCity LightInflect Health

Kinomatickinomatic.cominJun 2026

Kinomatic provides personalized orthopedic surgery planning that considers a patient's entire anatomy and biomechanics rather than treating each joint independently.

Digital HealthHealthtechMedical DevicesArroyo Grande, US

Bruce Brassfield(Executive Officer)inShaun Lea(Executive Officer, Director)inChristopher Fries(Executive Officer)inSamantha Myers(VP of Brand & Experience)inBrian Beckrestin

BoardRobbie Greenglass(Director)in

Koneksakoneksahealth.comin𝕏

Koneksa is a remote clinical evidence platform that enables studies across therapeutic areas using validated technology and comprehensive support services.

AI & Machine LearningBiotechDigital HealthMedical DevicesSaaS

Co-investorsMcKesson VenturesMerck Global Health Innovation FundMSD Global Health Innovation Fund

Legacygivelegacy.comin𝕏Seed

Legacy is a men's fertility and reproductive health company that provides sperm testing, analysis, and banking services.

Digital HealthHealthtechWellness & FitnessNew York City, US

Khaled Kteily(Founder)inSarah Steinle(Founder)in

Co-investorsAlumni VenturesAMK Investment OfficeBain Capital VenturesSamsung NextThe MBA FundTOLOKA SYNDICATE LIMITED+21 more

Lumerelumere.comin𝕏acquired by GHX

Lumere, part of GHX, provides clinically integrated supply chain and value analysis tools that help healthcare providers reduce costs and variation through evidence-based product decisions and analytics.

Cloud ComputingData & InfrastructureEnterprise SoftwareHealthtechSaaSChicago, US

Hani Elias(Executive Officer, Director)inTina Vatanka Murphy(President and CEO)inWill Danford(Executive Officer)inEric Meizlish(Executive Officer, Director)in

BoardJohn R. Burch, Jr.(Director)Bijan Salehizadeh(Director)in

Co-investorsBessemer Venture PartnersCorewell Health VenturesFCA Venture PartnersHeritage Group

Madaketmadakethealth.comin𝕏Jul 2018

Madaket offers an automated platform for managing healthcare provider data, handling compliance, data accuracy, and reporting.

Digital HealthHealthtechSaaSCambridge, US

James P. Dougherty(Executive Officer, Director)Jerry Held(Director)Archibald Cox(Director)

BoardGary Rieschel(Director)

Co-investorsF-Prime CapitalQiming Venture Partners USARaptor GroupExperian VenturesQiming Venture Partners

n1 Healthn1health.cominJan 2012

N1 Health offers a cloud-based AI platform that predicts which individuals to engage with specific health interventions to improve health outcomes, supported by its data science and customer experience teams.

AI & Machine LearningDigital HealthHealthtechRichmond, US

Allan Kahane(Executive Officer, Director)Tom Blue(Executive Officer, Director)Brian Hamilton(Executive Officer, Director)Sonja Horner(Executive Officer, Director)

Co-investorsHealthTrend Capital

Nice Healthcarenice.healthcarein𝕏Jun 2025

Nice Healthcare provides on-demand primary care and health services that come to patients' locations, aiming to reduce costs and improve accessibility compared to traditional clinic-based care.

Digital HealthEnterprise SoftwareHealthtechRoseville, US

Thompson Aderinkomi(Co-Founder & CEO)inGenevieve Swenson(Co-Founder & COO)in

BoardAllison Santos(Co-Founder & Chief Business Officer)inRobert M. Greenglass(Director)Partha Sarathi Mishra(Director)in

Co-investorsConductive VenturesDNA CapitalGROOVE CAPITALHeadwater VenturesIndie.vc

Persimmonpersimmon.lifein𝕏Jul 2021

Persimmon is a medical aesthetics and wellness platform that connects users with local licensed providers for at-home treatments and telehealth consultations.

Digital HealthHealthtechMarketplacesWellness & FitnessSan Francisco, US

Mark Hadfield(Executive Officer, Director)inMatthew Bartlett(Executive Officer, Director)in

Co-investorsCadron Capital PartnersCartan CapitalDecathlon Capital PartnersDraper AssociatesIPD CapitalSeed Healthcare+1 more

PLENFULplenful.comin

Plenful is an AI platform that automates complex administrative workflows in pharmacy operations, designed for healthcare organizations and pharmacy teams.

AI & Machine LearningEnterprise SoftwareHealthtechSaaSSan Francisco, US

Joy Liu(Founder)in

Co-investorsArtisanal VenturesBessemer Venture PartnersNight CapitalNotable CapitalTq Ventures LlcSusa Ventures

RUBICON MDrubiconmd.comin𝕏Feb 2020

RubiconMD provides a configurable virtual consultation platform that connects primary care providers with board-certified specialists across multiple specialties to improve patient access to specialty care.

Digital HealthHealthtechSaaSNew York, US

Carlos Reines(Founder)inGil Addo(Founder & CEO)inGilbert Addo(Executive Officer, Director)

BoardRajeev Singh-Morales(Director)Laura Veroneau(Director)Enrico Picozza(Director)

Co-investorsAlumni VenturesFCA Venture PartnersHLM Investment PartnersMetaplanetMundi VenturesOptum Ventures+3 more

SimpliFedsimplifed.usinFeb 2025 · $4M

SimpliFed provides a maternal health operating system delivering virtual care and support for parents during pregnancy, postpartum, and baby feeding.

Digital HealthFemTechHealthtechIthaca, US

Andrea Ippolito(Executive Officer, Director)in

BoardCat Hernandez(Director)Stephen Bruso(Director)

Co-investors3CC | Third Culture CapitalElizabeth Street VenturesTBD AngelsThe Artemis FundThe Venture CollectiveCultivation Capital+1 more

TimeDoc Healthtimedochealth.comin

TimeDoc Health provides care management services including chronic care management and remote patient monitoring, supported by clinical teams that coordinate patient care.

Digital HealthHealthtechSaaSChicago, US

William Boeglin(Executive Officer, Director)inChris Knoff(Executive Officer, Director)in

BoardTim Streit(Executive Officer, Director)in

Co-investorsBreak Trail VenturesChaifetz GroupGrand VenturesSerra VenturesVocap PartnersAldrich+2 more

Virgovirgosvs.comin𝕏Aug 2022

Virgo develops foundation models and AI software for endoscopy, enabling gastroenterologists to analyze colonoscopy videos for diagnostic scoring, patient outcome prediction, and clinical trial acceleration.

AI & Machine LearningFintechHealthtechMedical DevicesSan Francisco, US

Matt Schwartz(Founder)Paul Thomas Croft(Executive Officer)Jonathan Frost(Executive Officer)

Co-investorsCeltic House Asia PartnersCerity Partners VenturesFCA Venture PartnersTechstarsFCA Health Innovations QPTom Williams

Wellframewellframe.com𝕏

Wellframe provides digital member engagement and care management solutions for health plans.

Digital HealthHealthtechSaaS

Jacob Sattelmair(Founder)inDr Trishan Panch(Founder)inArchit Bhise(Founder)Trishan Panch(Founder)Vinayak Ramesh(Founder)

Co-investorsBlue Venture FundsF-Prime CapitalThreshold VenturesBlueCross BlueShield Venture PartnersDFJHealth Velocity Capital

Zipnosis Inczipnosis.comin𝕏

Fabric (formerly Zipnosis) provides an end-to-end care access platform and virtual care services that combine conversational AI and physician-built clinical logic to automate patient intake, triage, routing, and clinical documentation.

AI & Machine LearningDigital HealthHealthtechMinneapolis, US

Jonathan D. Pearce(Executive Officer, Director, Promoter)inRichard Eric Bosler(Executive Officer)Rebecca L. Hafner-Fogarty(Executive Officer)Scott Booher(Executive Officer)Kevin Smith(Executive Officer)

BoardAl Wiegman(Director)

Co-investorsArthur VenturesAscension VenturesHyde Park Venture PartnersLemhi Ventures

Other

Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.

1 DOC WAYClariFiCVRDDocNowGENEVA HEALTHCAREKoneksa HealthManifoldNicePerimeterRedbrick HealthVentricle HealthZIZI

Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.

Exits · 4

4 acquisitions · showing 3

Curedacq. by InnovaccerLumereacq. by GHXRedbrick Healthacq. by Marlin Equity Partners (merged into Virgin Pulse)

Portfolio news

latest coverage across their companies

Frequently asked questions

How many investments has Waterline Ventures made?
Waterline Ventures has 45 tracked investments, 4 of which have exited, including 4 dated in the last 24 months.
What stage does Waterline Ventures invest at?
Waterline Ventures invests at the Growth stage.
What sectors does Waterline Ventures focus on?
Waterline Ventures focuses on Digital Health, Healthtech, Medical Devices, Mental Health.
Where is Waterline Ventures located?
Waterline Ventures is headquartered in Cambridge, US.
Does Waterline Ventures lead rounds?
Waterline Ventures has led 3 of the 4 rounds where its role is on record.
Who does Waterline Ventures co-invest with?
Waterline Ventures most often shares deals with FCA Venture Partners, CU Healthcare Innovation Fund, Bessemer Venture Partners, among 99 tracked co-investors.

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