OSF Ventures
Corporate VCPeoria · Seed–Series A · 17 people tracked
Investment thesis
OSF Ventures invests as part of an investment syndicate in companies at post-seed stages that align with OSF HealthCare's key objectives and innovation strategy. It focuses on healthcare solutions that improve patient outcomes, enhance patient experience and reduce the cost of care, and it prioritizes companies interested in collaborating with OSF HealthCare's clinicians and other professionals. Beyond capital, the firm positions its investment as a partnership, offering access to its innovation teams and clinical subject matter experts to help portfolio companies test and refine concepts, speed adoption and scale their impact.
Source: firm website, verified Aug 3, 2026.
Team · 17 people
from the firm's website & public directoriesWhat they invest in
from 24 of 38 portfolio companiesHealthtech ×21Digital Health ×14AI & Machine Learning ×9Medical Devices ×9Biotech ×5Deep Tech ×3Data & Infrastructure ×2Enterprise Software ×2
HQs:United States×18
Investments · 38 tracked
founders shown can be your intro pathBy year:2024 · 12022 · 12018 · 12017 · 12015 · 15 dated
Health Catalyst provides data analytics, AI-powered insights, and healthcare solutions to help hospital systems and healthcare organizations improve clinical, financial, and operational outcomes.
AI & Machine LearningData & InfrastructureHealthtech
410 Medical makes LifeFlow, a hand-operated rapid infuser that lets clinicians quickly deliver blood or fluids to critically ill patients needing volume resuscitation.
HardwareHealthtechMedical DevicesDurham, US
Mark Donald Piehl(Executive Officer, Director)KYLE CHENET(Executive Officer, Director)Mike Liddell(Manager)Lukas Miller Roush(Manager)
BoardJEFF TERRELL(Director)STANLEY D. LYNALL(Director)
Provides treatment of biliary and urinary blockages, eliminating a second invasive procedure; acquired by Merit Medical Systems in June 2019.
Cala Health develops non-invasive prescription therapies for movement disorders, starting with a treatment for hand tremor and essential tremor.
Deep TechDigital HealthHealthtechMedical DevicesSilicon Valley, US
Kate Rosenbluth, PhD(President & Chief Innovation Officer)Deanna Harshbarger(Chief Executive Officer)
Cardiosense develops the CardioTag, a noninvasive point-of-care cardiac monitoring device that measures pulmonary capillary wedge pressure to enable early detection and management of worsening heart failure across emergency, inpatient, and outpatient settings.
AI & Machine LearningDigital HealthMedical DevicesChicago, US
Omer Tolga Inan(Director)Amit K. Gupta(Executive Officer, Director)Andrew Michael Carek(Executive Officer)
BoardJeff Terrell(Director)Daniel Gottlieb(Director)
Remote care management platform focused on early, preventive care; acquired by Best Buy in October 2021.
HealthtechSpringfield, US
Colleen Kraft(Director)Sanaz Cordes(Executive Officer, Director)Rachel Robinson(Executive Officer, Director)
BoardMark Bakken(Director)
Endotronix develops the Cordella PA Sensor and Heart Failure System, an FDA-approved implantable pulmonary artery sensor and remote monitoring platform for managing NYHA class III heart failure.
Digital HealthHealthtechMedical DevicesWoodridge, US
Jonathan Jonas(Director)Harry Rowland(Executive Officer, Director)Raymond S. Barrett, Jr.(Director)Anthony I Nunez(Executive Officer, Director)Sam R. Leno(Director)Leslie A. Saxon(Director)
Epitel develops REMI, a wireless EEG monitoring system with AI-powered seizure detection for use in healthcare facilities and ambulatory settings.
AI & Machine LearningHealthtechMedical DevicesSalt Lake City, US
BiotechSt. Louis, US
Troy Long(Executive Officer)Jeffrey Blair(Director)Tim Blair(Executive Officer)Eric Moessinger(Director)Robert Mitchell(Director)Thomas Hillman(Director)
Exo is a company backed by leading venture capital and corporate investors focused on innovative technologies, with particular emphasis on healthcare, bioelectronic medicines, materials science, and deep technology solutions.
AI & Machine LearningBiotechDeep TechHealthtechMedical Devices
Software that digitally augments clinicians to improve diagnostic accuracy; acquired by Stryker in September 2021.
hellocare.ai is an end-to-end virtual care delivery platform combining software, hardware, and AI to support virtual nursing, virtual sitting, telehealth, and remote patient monitoring.
AI & Machine LearningDigital HealthHealthtech
Humata provides an end-to-end platform to streamline prior authorization processes in healthcare, reducing delays and improving care access for patients.
AI & Machine LearningDigital HealthEnterprise SoftwareHealthtech
Jeremy Friese(Founder, MD)in
Inflammatix develops host-response-based molecular diagnostics tests to identify acute infections and sepsis in emergency and critical care settings.
AI & Machine LearningBiotechHealthtechMedical DevicesBurlingame, US
Tim Sweeney(Co-Founder and CEO)Purvesh Khatri(Co-Founder and Chief Scientist)JONATHAN ROMANOWSKY(Executive Officer)KENNETH BAHK(Director)DAVID PERSING(Director)STEVEN TABLAK(Director)
Care Hospice is a regional hospice provider serving patients across the southern and eastern United States from more than 25 locations in 8 states.
Digital HealthHealthtech
Creates industry-leading mobile and AR training software and games for physicians.
OSF HealthCare is a health care provider operating hospitals and clinics across Illinois and Michigan, offering services including cancer treatments such as proton therapy and brachytherapy, digital health through OSF OnCall, and clinical research.
Digital HealthHealthtech
BiotechPhoenix, US
Grace Colon(Director)Scott Morris(Executive Officer)David Neal(Executive Officer)David Mallery(Executive Officer, Director)Erin Curley(Director)Carey Ng(Director)
PatientWisdom (now part of NRC Health) provides a patient experience tool that integrates with electronic health records, surfacing patient preferences, goals, risks, and past-visit context to care teams via a MyView summary.
Digital HealthHealthtechSaaSNew Haven, US
Gregory Makoul(Executive Officer, Director)Matthew Storeygard(Director)Henry Schaffer(Executive Officer)Eric Langshur(Director)
PhotoniCare develops OtoSight, an FDA-cleared optical coherence tomography device for non-invasive assessment and monitoring of middle ear infections in healthcare facilities.
Deep TechDigital HealthHealthtechMedical DevicesDurham, US
Ryan Shelton(CEO)Cary Vance(Executive Officer, Director)Gary Durack(Member of the Board of Directors)Stephen Boppart(CMO)
BoardPatrick Zeller(Director)Dale Grogan(Director)
Applies AI to help health care providers make faster, informed decisions to improve patient outcomes.
Pieces Technologies is a physician-led AI company whose cloud-hosted Pieces Intelligence Platform generates clinical documentation and summaries—such as progress notes, discharge summaries, and care plans—directly within the EHR to assist physicians, nurses, and case managers.
AI & Machine LearningDigital HealthHealthtechDallas, US
Ruben Amarasingham(CEO & Founder)
HealthtechWaltham, US
Jenny Freeman(Executive Officer, Director)Jaideep Mehta(Director)Kamen Bliznashki(Executive Officer)Svetlana Panasyuk(Executive Officer)Peter Aranow(Director)
ShiraTronics is a medical device company developing an implantable device to treat chronic migraine disease.
BiotechHardwareHealthtechMedical DevicesBrooklyn Park, US
Robert Binney(Executive Officer, Director)
BoardJoyce Erony(Director)Zack Scott(Director)Brad Vale(Director)Casey Tansey(Director)Mudit Jain(Executive Officer, Director)
Platform enabling providers, health plans and employers to deliver digital health and therapeutic care; acquired by Amwell in August 2021.
Socially Determined provides social risk analytics through its SocialScape platform, combining person- and community-level data to show healthcare organizations where non-clinical factors drive costs and poor outcomes.
Data & InfrastructureDigital HealthHealthtechWashington, US
Modernizes lung and respiratory care to improve outcomes and streamline care coordination.
Exits · 5
IPOs and acquisitions across the tracked portfolioHealth CatalystNASDAQ: HCATBrightWateracq. by Merit Medical SystemsCurrent Healthacq. by Best BuyGaussacq. by StrykerSilverCloud Healthacq. by Amwell
Portfolio news
latest coverage across their companiesEpitel · frontlines.io · Nov 6, 2025
Cala · startuphealth.com · Oct 28, 2025
Frequently asked questions
- What stage does OSF Ventures invest at?
- OSF Ventures invests at the Seed, Series A stages.
- What sectors does OSF Ventures focus on?
- OSF Ventures focuses on Biotech, Digital Health, Healthtech, Medical Devices.
- Where is OSF Ventures located?
- OSF Ventures is headquartered in Peoria, US.
- Does OSF Ventures lead rounds?
- OSF Ventures typically participates in rounds rather than leading them.
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