Brightstone Venture Capital
Venture capitalMinneapolis · Seed–Growth · 11 people tracked
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Investment thesis
Brightstone manages a $100 million venture fund targeting early-growth stage opportunities, drawing on its partners' operating and investment experience. The firm invests across two core areas: technology (including data storage and management, virtual/augmented reality, AI/machine learning, enterprise security, blockchain, cloud infrastructure, and marketplaces) and life sciences (including regenerative medicine, stem cell, next-generation diagnostics, genomics and gene editing, medical devices, drug discovery tools and platforms, and personalized medicine). It aims to help entrepreneurs build exceptional companies.
Source: firm website, verified Sep 27, 2026.
Team · 11 people
from the firm's website & public directoriesWhat they invest in
from 23 of 32 portfolio companiesBiotech ×7Healthtech ×7AI & Machine Learning ×6Enterprise Software ×6SaaS ×6Creator Economy ×3Data & Infrastructure ×3Gaming ×3
HQs:United States×21
Who they back
founder profiles across 15 portfolio companiesFounding team size:solo founder×42 founders×73 founders×4
What their founders studiedfrom 10 founders with field-of-study data
Computer Science ×4Engineering ×2Life Sciences ×2Medicine ×2Physics ×2
Accelerator rootsportfolio companies that came through a program
Investments · 32 tracked
founders shown can be your intro pathBy year:2024 · 12021 · 12019 · 12016 · 14 dated
Celcuity is a commercial-stage biotechnology company developing targeted cancer therapies for tumors involving the PAM (PI3K/AKT/mTOR) pathway, including breast, prostate, lung, endometrial, colon, and ovarian cancers.
BiotechHealthtechMedical DevicesMinneapolis, US
Lance G. Laing(Executive Officer, Director, Promoter)inBrian F. Sullivan(Executive Officer, Director, Promoter)inLance G. Laing, Ph.D.(Chief Science Officer, Vice President, Secretary and Director)Vicky Hahne(Executive Officer)in
BoardDavid F. Dalvey(Director)inRichard E. Buller(Director)
Board seatDavid Dalvey· per SEC Form D
Co-investorsNew Enterprise Associates (NEA)
HomeSpotter provides mobile and marketing software for real estate brokerages, teams, and agents, including automated listing ads across Facebook, Instagram, and the web, digital open house lead generation, and branded MLS search apps.
Marketing TechPropTechSaaSMinneapolis, US
Aaron Kardell(Executive Officer, Director)
Board seatDavid Dalvey· per SEC Form D
Co-investorsMatchstick VenturesSandalphon Capital
Afriex provides a remittance service enabling immigrants to transfer money to over 25 countries at low costs with rapid settlement.
FintechSan Francisco, US
Tope Alabi(Founder)inJohn Obirije(Founder)in
Co-investorsAdaverseDragonflyFoundersFuture AfricaMetastableOpen Opportunity Fund+10 more
BiotechHealthtechSt. Paul, US
Joshua Woolley(Executive Officer)inRyan Gladney(Executive Officer)Gary Graham(Executive Officer)Dan W. Gladney(Executive Officer, Director)inPeter DeLange(Executive Officer)inBruce A. Machmeier(Executive Officer)
Co-investorsAngel Physicians FundBroadview VenturesCatalyst Health VenturesPortfoliaXeraya CapitalBioStar Ventures
Brilliant offers interactive, adaptive online courses in STEM subjects, focused on math and coding, delivered through a personal tutor model.
AI & Machine LearningConsumerEdTech
Eli RossinSam SolomoninSilas Hundt(Founder)Sue Khim(Founder)in
Co-investors500 GlobalAngel Collective Opportunity FundCorazon CapitalLAUNCHNext Play VenturesNimble Partners+7 more
San Jose, US
Yiren Huang(Executive Officer, Director)Alan Armstrong(Executive Officer, Director)Joseph DeFranco(Executive Officer)
BoardLip Bu Tan(Director)inBen Yu(Director)inBill Moore(Director)
Co-investorsCastor VenturesCisco InvestmentsM12 (Microsoft's Venture Fund)We VenturesCelesta CapitalDell Technologies Capital+1 more
CodeStream built a developer collaboration tool that brought code discussion, review, and issue tracking directly into the IDE, integrating with editors like VS Code and JetBrains.
AI & Machine LearningDeveloper ToolsEnterprise SoftwareSaaSNew York City, US
Claudio Pinkus(Founder)in
Co-investorsPJCY Combinator342 CapitalCTC VenturesCypher CapitalFriale+3 more
End-to-end commercial real estate platform for brokers, agents, tenants and owners; raised a $40M Series B.
Michael DeGiorgio(Founder)inLuke Morris(Founder)
Co-investorsBaroda VenturesFJ LabsFounder CollectiveFreestyle CapitalHemisphere Ventures LLCHypothesis+11 more
Cryosa develops an incisionless medical treatment that uses controlled cooling to reduce tissue and open airways.
BiotechHealthtechMedical DevicesArden Hills, US
Laura Stoltenberg(Executive Officer, Director)in
BoardDavid Belitz(Director)inDoug French(Director)James Eadie(Director)Donald Gonzales(Founder and Chief Medical Officer)
Co-investorsSolas BioVentures
Eternal is a Los Angeles NFT marketplace for trading Twitch streamer clips, a Y Combinator W20 company now listed as acquired.
ConsumerGamingLos Angeles, US
Jeffrey Tong(Founder)inAlex Mather(Founder)inReggie James(Founder)
Co-investorsArrington CapitalCoinbase VenturesY Combinator468 CapitalAmbush CapitalArrington XRP Capital+17 more
FLYR provides a modular Offer & Order retailing platform for airlines, layered on top of existing passenger service systems to enable omnichannel shopping carts, dynamic AI-driven pricing, marketplace bundling of flights with hotels and activities, post-booking servicing, and cross-airline commerce.
AI & Machine LearningB2B MarketplacesEnterprise SoftwareSaaSTravel & HospitalitySan Francisco, US
Alex Mans(Founder and Chief Executive Officer)inCyril Guiraud(Co-Founder and Former Chief Marketing Officer)inJean Tripier(Executive Officer, Director)
BoardUllas Naik(Director)inPankaj Shah(Director)
Co-investorsAllMobile FundBeyond CapitalBoeing HorizonX VenturesCota CapitalHaymaker VenturesImpact Ventures+11 more
Gravie provides health benefits products for small and midsize businesses, including its flagship Comfort level-funded health plan with zero-cost coverage of common services, as well as traditional copay/HSA plans and ICHRA administration.
Digital HealthHealthtechInsurTechMinneapolis, US
Abir Sen(Founder)Marek Ciolko(Founder)Marlon Cush(Executive Officer)inDan Schabold(Executive Officer)inSteve Wolin(CEO)inJill Prevost(Executive Officer, Promoter)in
Co-investorsFirstMark CapitalGeneral AtlanticK2 HealthVenturesNat TurnerWormhole CapitalAberdare Ventures+2 more
Intact Therapeutics develops next-generation biopharmaceutical therapies for gastrointestinal diseases to address unmet clinical needs.
BiotechHealthtechSan Francisco, US
Ravi Pamnani(Founder)inSidhartha Sinha(Founder)in
Co-investorsY CombinatorHanmi HealthcareStanford UniversityVenture Investment Associates
Roblox is a platform where users create and play user-generated games and experiences, serving gamers and developers of various ages.
AI & Machine LearningCreator EconomyData & InfrastructureEnterprise SoftwareGamingSan Francisco, US
Mark Stauber(Founder)inJaeyong Sung(Founder)in
Co-investorsAAF Management Ltd.GFR FundY CombinatoreFundFrialeKhosla Ventures+3 more
Miromatrix develops fully biologic organs using decellularization and recellularization technology for transplant patients.
BiotechLongevityMedical DevicesEden Prairie, US
Jeff Ross(Executive Officer)Robert Cohen(Executive Officer, Director, Promoter)
BoardRonald Eibensteiner(Director)Timothy Flynn(Director)Walter Sembrowich(Director)Timothy J. Pawlenty(Director)
Mosaic is a general contractor for build-to-rent (BTR) residential communities, combining construction services with proprietary software to plan, schedule, contract, and deliver homes at scale.
Construction TechPropTechSaaSPhoenix, US
Salman Ahmad(Founder & CEO)inSep Kamvar(Founder)
Co-investorsAndreessen HorowitzBuilding VenturesAZ-VCFounders FundGreylock PartnersInnovation Endeavors+9 more
Mosaic offers a tool that aggregates and centralizes AI coding sessions in one place, distributed via a Homebrew package for developers and AI agents.
AI & Machine LearningDeveloper ToolsEnterprise SoftwareSan Francisco, US
Shubham Patil(Founder)inDorsa Rohani(Founder)inAdish Jain(Founder)inBijan Moallemi(Founder)Kyle Wade(Founder)inSalman Ahmad(Founder)
Co-investorsVela PartnersY CombinatorFoxmont Capital PartnersGeneral CatalystGrey Street PartnersOurCrowd+3 more
ResistanceBio develops treatments to address drug resistance in cancer patients.
BiotechHealthtechSan Francisco, US
Nicholas Goldner(Founder)inChristopher Bulow(Founder)inKYLE LAPHAM(Executive Officer, Director)
BoardOMRI AMIRAV-DRORY(Director)in
Co-investorsAlumni VenturesFifty YearsY CombinatorAsymmetry VenturesCantos VenturesCentennial Investors+11 more
ShareFile provides secure file sharing, document collection, e-signature capabilities, and automated workflow management for teams collaborating with clients, partners, and vendors.
Enterprise SoftwareSaaS
Co-investorsAstellaBlack Diamond VenturesCID CapitalConcord Health PartnersH Venture PartnersRiverVest Venture Partners+1 more
28bio (formerly StemoniX Medical Tech) develops human induced-pluripotent-stem-cell-derived 3D neural organoid platforms, including CNS and PNS models, used to measure human neural activity in vitro.
BiotechEden Prairie, US
Yung-Ping Yeh(Executive Officer, Director, Promoter)Ryan Gordon(Executive Officer)Murdoc Khaleghi(Executive Officer)Robert Petcavich(Executive Officer, Director, Promoter)
BoardSteven Snyder(Director)Paul Hansen(Director)
Co-investorsAlumni VenturesRockies Venture Club
Versus provides an interactive content platform that enables audiences to make predictions and express opinions about live and on-demand entertainment content like TV shows and sports.
AI & Machine LearningCreator EconomyMedia & Entertainment
John Vitti(Founder & CEO)
Co-investors3Lines Venture Capital7BC Venture Capitalalphabet angelsBeresford VenturesEvolution VenturesLigo Partners LLC+11 more
Viosera Therapeutics is a biotechnology company founded to develop resistance-proof antimicrobial drugs.
Co-investorsDreamers VC
Vori Health is a nationwide specialty medical practice that treats back, neck, and joint pain using board-certified orthopedic specialists and integrated care teams.
Digital HealthHealthtechWellness & FitnessNashville, US
Ryan Grant(Executive Officer, Director)Mary O'Connor(Executive Officer, Director)inRyan A. Grant, MD, MS, MBA, FAANS(Founder)in
BoardHui Cheng(Director)inMohamad Makhzoumi(Director)inJane Suh(Director)in
Co-investorsAlleyCorpAscension VenturesEcho Health VenturesGood FriendsIntermountain HealthNew Enterprise Associates (NEA)+1 more
VRChat is a social virtual reality platform where users explore user-generated worlds, use custom avatars, and connect with others across PC, standalone VR headsets (Meta Quest, Pico), and mobile.
Creator EconomyGamingSocialHouston, US
Graham Gaylor(Manager)inJesse Joudrey(Manager)
Co-investorsGFR FundMakers FundAnthos CapitalHTCRothenberg Ventures
Wasabi provides low-cost cloud object storage for businesses storing data such as backups, medical images, surveillance footage, financial records, and multimedia.
Cloud ComputingCybersecurityData & InfrastructureEnterprise SoftwareBoston, US
Jeffry Flowers(Executive Officer, Director)David Friend(Founder)inJeff Flowers(Founder)inMike Welts(Executive Officer)Michael Bayer(Executive Officer)inMarty Falaro(Executive Officer)in
Co-investorsAlumni VenturesBasecamp FundBoston Harbor AngelsEnergy Impact PartnersEQx FundFoothill Ventures+8 more
Xplore provides space infrastructure and satellite operations services to commercial, government, and nonprofit organizations.
Cloud ComputingData & InfrastructureSaaSSpace Tech
Jeff Rich(Chief Executive Officer)Dave Claussen(Chief Technology Officer)David Floyd(Engineering Director)inLisa Rich(Chief Operating Officer)Henry Lin(Chief Financial Officer)in
Co-investorsAlumni VenturesBatshit Crazy VenturesHelios CapitalIndustrious VenturesSand Hill AngelsStarbridge Venture Capital Llc+5 more
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
BitesquadFlipgridLifeLensStemoniX
Exits · 4
1 IPOs · 3 acquisitions · showing 3CelcuityNASDAQ: CELCCodeStreamacq. by New RelicJido Mapsacq. by Roblox
Portfolio news
latest coverage across their companiesGravie · trysignalbase.com · Aug 3, 2026
Wasabi, Inc. · wasabi.com · Jan 21, 2026
IPO stake values · per SEC filings
Value of this firm's stake in each portfolio company at its IPO price, from the prospectus principal-stockholder table.
| Company | Owned | IPO price | At IPO | Stake value |
|---|---|---|---|---|
| Celcuity | 2.6% | $9.50 | Sep 2017 | $2.4M |
Source: SEC S-1 / 424B prospectus filings. Stake value = shares beneficially owned × the initial public offering price, as disclosed — a market value at IPO, not a return multiple (the firm's original cost is not disclosed).
Frequently asked questions
- How many investments has Brightstone Venture Capital made?
- Brightstone Venture Capital has 32 tracked investments, 4 of which have exited.
- What stage does Brightstone Venture Capital invest at?
- Brightstone Venture Capital invests at the Seed, Series A, Growth stages.
- What is Brightstone Venture Capital's typical check size?
- Brightstone Venture Capital typically writes checks of $250K – $10M.
- What sectors does Brightstone Venture Capital focus on?
- Brightstone Venture Capital focuses on AdTech, AI & Machine Learning, B2B Marketplaces, Biotech, Cloud Computing, Crypto & Web3, Cybersecurity, Data & Infrastructure, Deep Tech, Digital Health, Enterprise Software, Healthtech, Marketplaces, Medical Devices, Semiconductors, Space Tech.
- Where is Brightstone Venture Capital located?
- Brightstone Venture Capital is headquartered in Minneapolis, US.
- Does Brightstone Venture Capital lead rounds?
- Yes, Brightstone Venture Capital leads investment rounds.
- Who does Brightstone Venture Capital co-invest with?
- Brightstone Venture Capital most often shares deals with Alumni Ventures, Y Combinator, Ligo Partners LLC, among 107 tracked co-investors.
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