Pittsburgh · Pre-Seed–Series A · 47 people tracked
Investment thesis
Innovation Works focuses on nurturing the tech ecosystem in Southwestern Pennsylvania, supporting early-stage entrepreneurs with a continuum of resources tailored to each startup's stage. Its programming spans youth initiatives, one of the country's top accelerators, and grants that help manufacturing startups scale. The organization pairs capital with mentorship and operational support led by experienced entrepreneurs, aiming to help founders go further faster and to strengthen the regional innovation economy.
Source: firm website, verified Aug 7, 2026.
Team · 47 people
from the firm's website & public directoriesFounder mafia
2 people who came through Innovation Works went on to found or lead other companies.
What they invest in
from 5 of 6 portfolio companiesFuture of Work ×2SaaS ×2Advanced Manufacturing ×1Biotech ×1Data & Infrastructure ×1Enterprise Software ×1Fintech ×1Hardware ×1
HQs:United States×3
Portfolio companies · 6 tracked
alumni founders can tell you what the program is really likeDuo Oncology is a clinical-stage company developing tumor-activated prodrug combinations intended to replace toxic multi-agent chemotherapy with single medicines that concentrate activity in tumors.
BiotechHealthtechPittsburgh, US
SONG LI(Director, Promoter)SAM ROTHSTEIN(Executive Officer, Director, Promoter)JING-ZHOU HOU(Executive Officer, Director, Promoter)Sam Rothstein(CEO & Cofounder)KATHERINE EICHINGER(Executive Officer)Katherine Eichinger(Chief Operating Officer)
Co-investorsUlu VenturesNuFund Venture GroupNuFund
Exchangelodge provides a data and operations management platform for private capital markets, ingesting, validating, enriching, and delivering data across asset classes.
Data & InfrastructureFintechSaaS
Co-investorsBeresford Ventures
Calendly is a scheduling platform that integrates with Microsoft Teams to automatically generate and include Teams video conferencing links in calendar events.
Enterprise SoftwareFuture of WorkSaaS
Tope Awotona(Founder)in
Co-investorsAlumni VenturesAtlanta Tech VillageBasecamp FundCoatue ManagementCVX VenturesFusion+11 more
The Robotics Factory runs create, accelerate, and scale programs that help pre-seed robotics start-ups build production-ready products, offering funding, in-house prototyping, and design assistance.
Advanced ManufacturingHardwareRoboticsPittsburgh, US
Portfolio news
latest coverage across their companiesCalendly · techfundingnews.com · Oct 29, 2025
Duo Oncology · innovation.pitt.edu · Apr 8, 2025
Frequently asked questions
- What stage does Innovation Works invest at?
- Innovation Works invests at the Pre-Seed, Seed, Series A stages.
- What is Innovation Works's typical check size?
- Innovation Works typically writes checks of $100K – $300K.
- What sectors does Innovation Works focus on?
- Innovation Works focuses on Advanced Manufacturing, Biotech, Consumer, Data & Infrastructure, Enterprise Software, Hardware, Medical Devices, Robotics, SaaS, Sector Agnostic.
- Where is Innovation Works located?
- Innovation Works is headquartered in Pittsburgh, US.
- Who does Innovation Works co-invest with?
- Innovation Works most often shares deals with Coatue Management, Gener8tor, ICONIQ, among 17 tracked co-investors.
Media · Podcasts & interviews
featuring the teamFounders on Fire with Ven Raju, CEO of Innovation Works
Tech Trailblazers Startup Podcast · Ven Raju
Images
Co-investors · 21
Bessemer Venture Partners is a global venture capital firm that partners with entrepreneurs across enterprise, consumer, and healthcare sectors from early stages through growth.
Crosslink Capital is a San Francisco-based venture capital firm investing in enterprise and consumer technology startups across North America.
Pareto Holdings is an early-stage investment and company-building firm headquartered in the United States that operates globally. It has never raised outside capital and is self-funded by design.
TSV Capital (TSVC), formerly TEEC Angel Fund, is a Silicon Valley seed-stage venture firm that backs technical founders at the earliest stages, having invested in over 200 early-stage companies.
Scribble Ventures is an early-stage venture firm run by product and go-to-market leaders from OpenAI, Meta, Twitter, and a16z, backing AI native founders at the pre-seed and seed stages.
Amazon Web Services (AWS) is Amazon's Seattle-based cloud computing division, offering more than 240 cloud and AI services to customers ranging from startups to large enterprises. Its infrastructure spans over 120 availability zones across dozens of geographic regions worldwide. It is a technology provider rather than an investment firm.
Pfizer Venture Investments is a strategic venture fund that doesn't require product or technology rights as a condition of investing, giving founders independence while still aiming for future collaboration with Pfizer, and its team blends venture investing with business development and drug discovery expertise to back frontier scientific bets—such as neuroscience, in-vivo cell engineering, dark-genome target discovery, and the blockchain-based longevity accelerator VitaDAO—that many biotech investors avoid. The fund also runs an active China strategy through a locally based venture vehicle and direct investments like OTR Therapeutics, and it has become a channel for strategic deals, with portfolio companies acquired by AbbVie, Ipsen, and Gilead/Kite.
Riverfront Ventures is an early-stage venture capital fund based in Pittsburgh that invests in early-growth stage technology companies, serving as the venture capital arm of Innovation Works.
Anzu Partners is an investment firm backing breakthrough clean tech, industrial, and life science technologies, working alongside founders through a team of investors, operators, scientists, and engineers.
Volition Capital is a Boston-based growth equity firm that invests in founder-owned, high-growth software, technology, and consumer companies, providing minority growth capital to help scale enduring businesses.
Allos Ventures is a Midwest-focused venture capital firm that invests in early-stage B2B software and tech-enabled services companies, drawing on decades of experience to take a hands-on approach.
▶9 more co-investors
Osney CapitalAvoro Capital AdvisorsQuake CapitalMonozukuri VenturesSeaX VenturesGreat North VenturesRincon Venture PartnersDraper Triangle3 Points Rising Ventures
Firms observed investing alongside Innovation Works, from public investor directories. Shared companies are the overlap with Innovation Works's recorded portfolio.
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