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Prolog Ventures

Venture capital

Clayton · Series A–Late Stage · 6 people tracked

Also known as PROLOG VENTURES HL II, LLC

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Investment thesis

Prolog Ventures backs early-stage companies advancing healthy lives in a healthy world. Its investment interests span consumer health and wellness, healthy foods and beverages, agriculture and sustainability, and health services. Portfolio examples include premium sparkling water, healthy children's foods, planet-friendly cover crops, and on-demand massage therapy, reflecting a focus on products and services that improve human and environmental health.

Source: firm website, verified Aug 25, 2026.

Stage
Series A–Late Stage
Check
$250K – $1M
HQ
Clayton, Missouri, US
Instruments
Equity
Founded
2001
AUM
$129M
VC funds
1
Tracked investments
22

Team · 6 people

from curated & public directories

What they invest in

from 9 of 22 portfolio companies

Healthtech ×4Medical Devices ×4AgTech ×3Biotech ×3AI & Machine Learning ×2Digital Health ×2FoodTech ×2Cleantech ×1

HQs:United States×6

Investments · 22 tracked

founders shown can be your intro path

By year:2018 · 12017 · 12016 · 22015 · 15 dated

CareDoxcaredox.cominAug 2016

CareDox (operating as SchoolCare) provides a digital health record platform for K-12 school nurse offices that manages immunizations, chronic disease information, and student health compliance reporting.

Digital HealthEdTechHealthtechForest Hills, US

Hesky Kutscher(Executive Officer, Director)

BoardGreg Goff(Director)Eyal Niv(Director)

Board seatIlya Nykin· per SEC Form D

Co-investorsKima VenturesDigitalis VenturesFirst Round CapitalTEXO VenturesWestern Technology Investment

Plastomics, Inc.plastomics.cominDec 2017SEC filingmedium confidence

Plastomics develops trait delivery technology for agriculture using cell biology, plant tissue culture, transformation, and molecular biology methods.

AgTechBiotechSt. Louis, US

Jeffrey Staub(Executive Officer, Director)Elizabeth Gallegos(Executive Officer)

BoardMartha Schlicher(Executive Officer, Director)inCharles Bolten(Director)Dave Duncan(Director)

Board seatBrian Clevinger· per SEC Form D · $3.5M raise · filed Mar 2021

Co-investorsBioGenerator VenturesFulcrum Global CapitaliSelect FundMissouri Technology CorporationCultivation Capital

Revive BrandsMay 2016SEC filingmedium confidence

Petaluma, US

Rebekah Lovett(Executive Officer)Marianne Lovett(Executive Officer)Sean J. Lovett(Executive Officer, Director)

BoardPeter Henig(Director)Bentley Hall(Director)

Board seatIlya Nykin· per SEC Form D · $3.5M raise · filed Jun 2016

Toma BiosciencesJul 2015SEC filingmedium confidence

Foster City, US

Gregory Jensen(Executive Officer)Wolfgang Daum(Executive Officer, Director)Lincoln Nadauld(Director)John Steuart(Executive Officer)

BoardPaul Conley(Director)

Board seatBrian Clevinger· per SEC Form D · $16.1M raise · filed Sep 2016

Zeelzeel.comJan 2018

On-demand massage service connecting customers with licensed massage therapists.

New York, US

BoardSamer Hamadeh(Executive Officer, Director)inRyan Freedman(Director)

Board seatIlya Nykin· per SEC Form D

Co-investorsAlpaca VCCorigin VenturesECP GrowthGrit Capital PartnersHemisphere Ventures LLCLightbank+4 more

Attune
Benson Hill Inc.bensonhill.comin

Benson Hill develops soybean seed varieties using plant genetics and AI-driven plant science to produce more nutritious and energy-dense soy for agriculture and food markets.

AgTechAI & Machine LearningFoodTech

Co-investorsActivant CapitalBioGenerator VenturesiSelect FundLewis & Clark VenturesManta Ray VenturesMercury Fund+1 more

CoverCresscovercress.comin𝕏

CoverCress Inc. develops agricultural products and seeds that enable farmers to convert idle winter fields into profitable crops.

AgTechCleantechClimate TechEnergy

Co-investorsBioGenerator VenturesFulcrum Global CapitalPrelude Ventures

Divergence
Drinkspindriftdrinkspindrift.com𝕏

Spindrift makes sparkling water and non-carbonated iced tea beverages using real squeezed fruit, with no concentrates.

ConsumerDirect to ConsumerFoodTech

Intellicyt
Kandu Healthin𝕏

Neurolutions develops IpsiHand, a brain-computer interface therapy system for stroke survivors to improve arm and hand movement at home.

AI & Machine LearningHealthtechMedical Devices

Co-investorsAscension VenturesExcelestar VenturesK2 HealthVentures

Kinnoskinnos.usin𝕏

Kinnos makes Highlight, a colorant additive for disinfectant wipes that provides real-time visual feedback on surface coverage and cleaning technique to healthcare facilities.

HealthtechMedical DevicesBrooklyn, US

Jason Kang(Executive Officer)Kevin Tyan(Executive Officer)Katherine Jin(Executive Officer)

Moleculeramoleculera.comin𝕏

Moleculera develops precision medicine technologies for identifying and treating immune-mediated disorders, including neuropsychiatric and cardiovascular conditions, using blood-based autoantibody testing panels, biobank data, and biomarker identification.

BiotechDigital HealthMedical Devices

Moleculera Biosciences

Biosciences company approaching a breakout moment in its field.

Nxthera
Plum
Revive Kombucharevivekombucha.comin

Functional beverage brand offering naturally-fermented kombucha.

Co-investorsBeechwood Capital

Sequoiavaccinessequoiavaccines.com

Sequoia Vaccines is a clinical-stage pharmaceutical company developing novel vaccines to prevent bacterial infections including urinary tract infections and small molecule treatments for certain cancers and lung infections associated with cystic fibrosis.

BiotechHealthtechMedical Devices

spindriftspindriftfresh.com

Premium sparkling water and beverages made with real squeezed fruit and zero added sugar.

Co-investorsAlmanac InsightsGryphonKarpReillyNew Ground VenturesRiverPark Ventures

Veniti
Veran

Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.

Portfolio news

latest coverage across their companies

Frequently asked questions

How many investments has Prolog Ventures made?
Prolog Ventures has 19 tracked investments.
What stage does Prolog Ventures invest at?
Prolog Ventures invests at the Series A, Late Stage stages.
What is Prolog Ventures's typical check size?
Prolog Ventures typically writes checks of $250K – $1M.
What sectors does Prolog Ventures focus on?
Prolog Ventures focuses on AgTech, Biotech, Consumer, Digital Health, FoodTech, Healthtech, Wellness & Fitness.
Where is Prolog Ventures located?
Prolog Ventures is headquartered in Clayton, US.
Who does Prolog Ventures co-invest with?
Prolog Ventures most often shares deals with BioGenerator Ventures, Corigin Ventures, Lightbank, among 27 tracked co-investors.

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