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Prolog Ventures

Venture capital

Clayton · Series A–Late Stage · 6 people tracked

Also known as PROLOG VENTURES HL II, LLC

Find your way into Prolog Ventures

553 people in our graph share verified history with the Prolog Ventures team — schools, employers, funds. One of them is your warm intro.

Catherine Matthesunlockedknows Greg Johnson · together at Kereos (overlapped)
knows the team · via Revive Kombucha
×5knows the team · via New Venture Partners
knows the team · via Zeel Networks
×4knows the team · via FirstMark
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Investment thesis

Prolog Ventures backs early-stage companies advancing healthy lives in a healthy world. Its investment interests span consumer health and wellness, healthy foods and beverages, agriculture and sustainability, and health services. Portfolio examples include premium sparkling water, healthy children's foods, planet-friendly cover crops, and on-demand massage therapy, reflecting a focus on products and services that improve human and environmental health.

Source: firm website, verified Sep 29, 2026.

Stage
Series A–Late Stage
Check
$250K – $1M
HQ
Clayton, Missouri, US
Instruments
Equity
Founded
2001
AUM
$129M
VC funds
1
Tracked investments
32
Acquisitions
2

Team · 6 people

from curated & public directories

Founder mafia

2 people who came through Prolog Ventures went on to found or lead other companies.

What they invest in

from 19 of 32 portfolio companies

Healthtech ×9Biotech ×7Medical Devices ×6AgTech ×4AI & Machine Learning ×3Digital Health ×3Circular Economy ×2Cleantech ×2

HQs:United States×16Belgium×1

Investments · 32 tracked

founders shown can be your intro path

By year:2020 · 22019 · 12018 · 12017 · 32016 · 22015 · 12012 · 22011 · 113 dated

CareDoxcaredox.cominAug 2016 · $16M

CareDox (operating as SchoolCare) provides a digital health record platform for K-12 school nurse offices that manages immunizations, chronic disease information, and student health compliance reporting.

Digital HealthEdTechHealthtechForest Hills, US

Hesky Kutscher(Executive Officer, Director)in

BoardGreg Goff(Director)Eyal Niv(Director)

Board seatIlya Nykin· per SEC Form D

Co-investorsKima Ventures7wire VenturesDigitalis VenturesFirst Round CapitalStartUp HealthTEXO Ventures+1 more

Plastomics, Inc.plastomics.cominDec 2017SEC filingmedium confidence

Plastomics develops trait delivery technology for agriculture using cell biology, plant tissue culture, transformation, and molecular biology methods.

AgTechBiotechSt. Louis, US

Jeffrey Staub(Executive Officer, Director)inElizabeth Gallegos(Executive Officer)in

BoardMartha Schlicher(Executive Officer, Director)inCharles Bolten(Director)Dave Duncan(Director)

Board seatBrian Clevinger· per SEC Form D · $3.5M raise · filed Mar 2021

Co-investorsBioGenerator VenturesFulcrum Global CapitaliSelect FundMissouri Technology CorporationCultivation Capital

Toma BiosciencesinJul 2015SEC filingmedium confidence

Foster City, US

Gregory Jensen(Executive Officer)inWolfgang Daum(Executive Officer, Director)in

BoardPaul Conley(Director)Mike Lucero(Director)John Steuart(Executive Officer)

Board seatBrian Clevinger· per SEC Form D · $16.1M raise · filed Sep 2016

Zeelzeel.comJan 2018

On-demand massage service connecting customers with licensed massage therapists.

New York, US

BoardSamer Hamadeh(Executive Officer, Director)inRyan Freedman(Director)

Board seatIlya Nykin· per SEC Form D

Co-investorsAlpaca VCCorigin VenturesECP GrowthFJ LabsGrit Capital PartnersHemisphere Ventures LLC+7 more

Benson Hill Inc.bensonhill.comin

Benson Hill develops soybean seed varieties using plant genetics and AI-driven plant science to produce more nutritious and energy-dense soy for agriculture and food markets.

AgTechAI & Machine LearningFoodTech

Co-investorsActivant CapitalBioGenerator VenturesGV (Google Ventures)iSelect FundLewis & Clark VenturesManta Ray Ventures+2 more

CleanSlate UVcleanslateuv.comin𝕏Apr 2020

CleanSlate UV manufactures UV-C sanitization devices for mobile phones and portable electronics, serving healthcare facilities, hotels, and other institutions seeking to reduce pathogenic contamination on high-touch devices.

CleantechHardwareHealthtechMedical Devices

Co-investorsMaple Leaf AngelsNEXT Canada

CoverCresscovercress.comin𝕏

CoverCress Inc. develops agricultural products and seeds that enable farmers to convert idle winter fields into profitable crops.

AgTechCleantechClimate TechEnergyOlivette, US

Jim Hedges(CEO)in

Co-investorsBioGenerator VenturesFulcrum Global CapitalPrelude VenturesCultivation Capital

Drinkspindriftdrinkspindrift.com𝕏

Spindrift produces sparkling water beverages with real fruit juice and zero added sugar for consumers seeking refreshing drinks with natural ingredients.

ConsumerDirect to ConsumerFoodTech

Bill(Founder & Chairman)

Co-investorsAlmanac Insights

JournelleinOct 2011

New York, US

Claire Chambers(Executive Officer, Director, Promoter)

BoardNiko Canner(Director)Ragheed Mitri(Director)

Kandu Healthin𝕏

Neurolutions develops IpsiHand, a brain-computer interface therapy system for stroke survivors to improve arm and hand movement at home.

AI & Machine LearningHealthtechMedical Devices

Co-investorsAscension VenturesExcelestar VenturesK2 HealthVentures

Kinnoskinnos.usin𝕏Mar 2020 · $6M

Kinnos makes Highlight, a colorant additive for disinfectant wipes that provides real-time visual feedback on surface coverage and cleaning technique to healthcare facilities.

HealthtechMedical DevicesBrooklyn, US

Jason Kang(Executive Officer)inKevin Tyan(Executive Officer)inKatherine Jin(Executive Officer)in

Co-investorsPartnership Fund for NYC

Moleculeramoleculera.comin𝕏

Moleculera Labs offers the Autoimmune Brain Panel, a diagnostic blood test that identifies autoimmune dysfunction in patients with treatment-resistant neuropsychiatric and behavioral symptoms.

BiotechDigital HealthHealthtechMedical Devices

Moleculeralabsmoleculeralabs.com𝕏

Moleculera Biosciences is a precision medicine company that develops blood-based immune-mediated autoantibody testing panels and AI-driven diagnostic tools to identify immune dysfunction underlying chronic neuropsychiatric and cardiovascular disorders, as well as Alzheimer's disease.

AI & Machine LearningBiotechDigital HealthMedical Devices

Co-investorsPlains Ventures

Reviverevive.beinAug 2017 · $7.5M

Revive is a real estate development company focused on sustainable urban housing projects and mixed-use property development in Belgium and Poland.

Circular EconomyConstruction TechImpact & Social GoodPropTechBrussels, BE

Nicolas Bearelle(Founder & Executive Chairman)inAlexandre Huyghe(Chief Executive Officer)in

Co-investorsEqual VenturesVictrixBanter CapitalBeechwood CapitalBlueberry VenturesCoalition Operators+2 more

Revivegetrevivehq.comAug 2017 · $7.5M

Revive (getrevivehq.com) offers a curated resale edit of sought-after fashion pieces from brands such as Anine Bing, Farm Rio, Ruti, Bloomingdale's, and Lululemon.

Circular EconomyE-commerceMarketplaces

Co-investorsMute VenturesBanter CapitalBeechwood CapitalBlueberry VenturesCoalition OperatorsEqual Ventures+2 more

Revive Kombucharevivekombucha.comin

Functional beverage brand offering naturally-fermented kombucha.

Co-investorsBeechwood Capital

Sequoia Sciencessequoiasciences.com

Sequoia Sciences is a biotechnology company developing vaccines, including a vaccine to prevent recurrent urinary tract infections, with programs spanning clinical development, regulatory strategy, and manufacturing.

BiotechHealthtechSaint Louis, US

GARY R ELDRIDGE, JR.(Executive Officer, Director)Gary Eldridge(Co-founder, President & CEO (Sequoia Vaccines))Kevin B. Bacon(President & CEO)inJim Spellmeyer(Chief Financial Officer)inMICHAEL J MERTZ(Director)GEORGE PAZ(Director)

Co-investorsCultivation Capital

Sequoiavaccinessequoiavaccines.com

Sequoia Vaccines develops vaccine treatments for infectious diseases, with a focus on prevention of recurrent urinary tract infections.

BiotechHealthtechMedical DevicesSan Diego, US

Gary Eldridge(President and CEO (since inception in 2012))Kevin B. Bacon(President & CEO)Michael Holmes

spindriftspindriftfresh.com

Premium sparkling water and beverages made with real squeezed fruit and zero added sugar.

Dave Burwickin

Co-investorsAlmanac InsightsGryphonKarpReillyNew Ground VenturesRiverPark VenturesVMG Partners

Veran Medicalveranmedical.comAcquired

St.

HealthtechSt. Louis, US

Scott Wrightstone(Executive Officer)inMaureen Oehler(Executive Officer)Jason Pesterfield(Executive Officer, Director)inRyan Denney(Executive Officer)inMark Hunter(Executive Officer)inRobert Powers(Executive Officer)in

Co-investorsRC CapitalRex Health VenturesSolas BioVenturesAdvantage Capital PartnersVensana CapitalVersant Ventures

Other

Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.

Revive BrandsAdigica HealthAltheus TherapeuticsArvegenixAttuneDivergenceIntellicytNxthera IncPlumSingulexVenitiVeran

Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.

Portfolio news

latest coverage across their companies

Frequently asked questions

How many investments has Prolog Ventures made?
Prolog Ventures has 32 tracked investments, 2 of which have exited.
What stage does Prolog Ventures invest at?
Prolog Ventures invests at the Series A, Late Stage stages.
What is Prolog Ventures's typical check size?
Prolog Ventures typically writes checks of $250K – $1M.
What sectors does Prolog Ventures focus on?
Prolog Ventures focuses on AgTech, Biotech, Consumer, Digital Health, FoodTech, Healthtech, Wellness & Fitness.
Where is Prolog Ventures located?
Prolog Ventures is headquartered in Clayton, US.
Who does Prolog Ventures co-invest with?
Prolog Ventures most often shares deals with Almanac Insights, BioGenerator Ventures, Corigin Ventures, among 33 tracked co-investors.

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