LRVHealth
Venture capitalActively deployingBoston · Seed–Late Stage · 28 people tracked
Also known as LONG RIVER CAPITAL MANAGEMENT II LLC
Investment thesis
LRVHealth positions itself as a healthcare-native investor rather than a generalist VC, using capital and strategic relationships to solve healthcare problems from within the system. The firm invests both with established, forward-looking healthcare organizations ready to lead change and in the innovative companies built to serve them. Its differentiator is an 'inside' model: portfolio companies gain not only capital but active engagement from strategic health system partners and leaders. LRVHealth emphasizes deep industry insight, an extensive network of health system executives, and long-term partnership to help early-stage founders scale within the complex healthcare landscape.
Source: firm website, verified Aug 25, 2026.
Team · 28 people
from the firm's website & public directories
What they invest in
from 40 of 59 portfolio companiesHealthtech ×35Digital Health ×25SaaS ×13AI & Machine Learning ×12Medical Devices ×10Enterprise Software ×7Biotech ×3Cybersecurity ×2
HQs:United States×34
Who they back
founder profiles across 12 portfolio companiesFounding team size:solo founder×92 founders×3
Investments · 59 tracked
founders shown can be your intro pathBy year:2025 · 72024 · 32023 · 32022 · 12021 · 12020 · 22018 · 12017 · 12014 · 221 dated
Phreesia provides a patient intake and engagement platform with automated tools for registration, insurance verification, appointment access, and payments used by healthcare organizations.
Digital HealthHealthtechSaaSNew York, US
Chaim Indig(Executive Officer, Director)Charles Kallenbach(Executive Officer)Thomas Altier(Executive Officer)Michael Weintraub(Director)Victor Kats(Director)Dusty Lieb(Director)
Co-investorsAscension VenturesBlue Venture FundsEscalate Capital PartnersHLM Venture PartnersLLRVantagePoint Capital Partners
Convergent Dental is a privately owned dental equipment and technology company whose flagship product, Solea, is a CO2 all-tissue laser cleared by the FDA that offers anesthesia-free, blood-free, and suture-free dental procedures.
Enterprise SoftwareHardwareHealthtechMedical DevicesNatick, US
Nathan P. Monty(Executive Officer, Director)Michael J. Cataldo(Executive Officer, Director)Rob Gershon(Chief Executive Officer)Mark Collins(Chief Financial Officer)Todd Hornsby(Chief Commercial Officer)
BoardBart Doedens(Director)
Board seatWilliam R. Cowen· per SEC Form D
Co-investorsArboretum VenturesTrinity Capital
Activ Surgical develops intraoperative surgical intelligence technology for surgeons, using AR, AI, machine learning, and sensing to display physiological structures and functions not visible to the naked eye.
AI & Machine LearningHealthtechMedical DevicesBoston, US
Peter Kim(Director)inMichael Ruehlman(Executive Officer)Todd Usen(Executive Officer, Director)
BoardEmily Casey(Director)Ashok Krishnamurthi(Director)inDavid Wells(Director)
Board seatWill Cowen· per SEC Form D
Co-investorsReimagined VenturesAlumni VenturesArtis VenturesBasecamp FundCastor Ventures (an Alumni Ventures Fund)Cota Capital+8 more
Censinet provides a risk management platform for the healthcare industry that connects vendors, products, AI technologies, and internal operations to the clinical and business functions they support.
CybersecurityHealthtechSaaSBoston, US
Board seatKeith FiglioliWord D. Peake, III· per SEC Form D
Co-investorsBallad VenturesExcelerate Health VenturesHLM Venture PartnersMemorialCare Innovation FundSchooner CapitalExcel Venture Management
Cleerly develops FDA-cleared, AI-driven analysis of noninvasive coronary CT (CCTA) imaging to characterize and quantify coronary artery disease.
AI & Machine LearningDigital HealthMedical DevicesDenver, US
James Min, MD(Founder)inLee Cooper(Director)Word D. Peake III(Director)Peter Justin Klein(Director)James K. Min(Executive Officer, Director)Louis Samson(Director)
Board seatWord D. Peake III· per SEC Form D
Co-investorsBattery VenturesBreyer CapitalInsight PartnersNew Leaf Venture PartnersVensana Capital
Diana Health provides personalized women's healthcare through collaborative teams of OB/GYNs, midwives, mental health therapists, dietitians, and wellness coaches.
Digital HealthFemTechHealthtechWellness & FitnessNew York, US
Kate Condliffe(Chief Executive Officer)
BoardBrenton Fargnoli(Director)inJeff De Flavio(Director)Payal Agrawal Divakaran(Director)inEllen Herlacker(Director)
Board seatEllen Herlacher· per SEC Form D
Co-investors.406 VenturesAlleyCorpNorwest Venture PartnersAlley Robotics Ventures
Humata provides an end-to-end platform to streamline prior authorization processes in healthcare, reducing delays and improving care access for patients.
AI & Machine LearningDigital HealthEnterprise SoftwareHealthtechMiami, US
Jeremy Friese(Founder, MD)inOscar Callejas(Executive Officer)inMichael Kolb(Executive Officer)inWord D. Peake(Director)Thomas Hawes(Director)Philip Fibiger(Executive Officer)in
Board seatWord D. Peake· per SEC Form D
Co-investors.406 VenturesBlue Venture FundsOptum VenturesOSF Ventures
IntelyCare operates a healthcare talent marketplace that connects nurses with care settings including hospitals, clinics, and other healthcare facilities.
B2B MarketplacesFuture of WorkHealthtechHR TechQuincy, US
Ike Nnah(Executive Officer, Director)David Coppins(Executive Officer, Director)Prince Nnah(Director)
Board seatKeith Figlioli· per SEC Form D
Co-investorsEastward Capital PartnersEndeavour VisionEquitage Ventures, L.L.C.Generator VenturesKaiser Permanente VenturesLongitude Capital+1 more
KeyCare builds virtual care technology and telehealth solutions to extend health system capacity and improve access to healthcare.
Digital HealthHealthtechSaaSChicago, US
Lyle Berkowitz, MDinSulabh Agarwal(Executive Officer, Director)inCarrie Nelson, MDinMike RobbinsinAndy JacksonJennifer Timm
Board seatWilliam R. Cowen· per SEC Form D
Co-investors2Flo Ventures8VCBold Capital PartnersHealthX VenturesCultivation Capital
MachineMetrics provides a manufacturing execution system (MES) with AI-powered machine monitoring for discrete manufacturers.
Advanced ManufacturingAI & Machine LearningSaaSEasthampton, US
Board seatWord D. Peake III· per SEC Form D · $11.4M raise · filed Dec 2018
Co-investorsLevel EquityMassVenturesTola CapitalHyperplane Venture Capital
HealthtechLexington, US
Christine Cournoyer(Executive Officer, Director)Melissa Cruz(Executive Officer, Director)Jennifer Carter(Executive Officer, Director)Jennifer Levin Carter(Executive Officer, Director)
BoardPeter McKay(Director)Joseph O'Connor(Director)
Board seatChristiana DelloRusso· per SEC Form D · $7M raise · filed Feb 2017
Reema Health provides behavioral health services combined with social needs navigation, using community care workers and a virtual care team to help members address unmet social needs such as food insecurity, housing, transportation, and loneliness.
Digital HealthHealthtechMental HealthMinneapolis, US
Matthew Swanson(Director)Amon Anderson(Director)Justin Ley(Executive Officer, Director)
BoardHelen Ciesielski(Director)Mike Cunningham(Director)
Board seatEllen Herlacher· per SEC Form D
Co-investorsDigitalis VenturesGROOVE CAPITALHC9 VenturesHeadwater VenturesMaC Venture CapitalMatchstick Ventures+2 more
Reimagine Care provides home-based oncology care combining Remi, an AI-powered assistant for cancer patients, with round-the-clock oncology-trained clinicians in a virtual care center.
AI & Machine LearningDigital HealthHealthtechNashville, US
Douglas French(Director)Dan Nardi(Mr. Nardi is the CEO and a director of the Issuer)Keith Figlioli(Director)Feby Abraham(Director)Chris Stenzel(Director)
BoardHarlan Levine(Director)
Board seatKeith Figlioli· per SEC Form D
Co-investorsCU Healthcare Innovation FundMartin VenturesMcKesson VenturesOncology Ventures
Austin, US
Mustafa Shabib(Executive Officer, Director)Joshua Hix(Executive Officer, Director)
Board seatKeith Figlioli· per SEC Form D · $12M raise · filed Nov 2023
Co-investorsAndreessen Horowitz
Sware offers the GxP Suite, a SaaS validation platform (Res_Q) that uses AI agents to manage software, plant/equipment, and medical device validation while maintaining audit readiness.
AI & Machine LearningHealthtechSaaSChelsea, US
Bryan Ennis(Co-Founder & Chief Quality Officer)inELLEN REILLY(Executive Officer, Director)BRYAN ENNIS(Executive Officer, Director)Ellen Reilly(Chief Executive Officer)inTheresa Pauzer(Chief People Officer)inEvan Raggi(Chief Commercial Officer)in
Board seatWilliam R. Cowen· per SEC Form D
Co-investorsFirst AnalysisInsight PartnersJumpstart CapitalNew Stack Ventures
Chicago, US
Benjamin Albert(Executive Officer, Director, Promoter)
BoardSid Chambless(Director)Robert Coppedge(Director)Michael Tudeen(Director)
Board seatKeith Figlioli· per SEC Form D
Co-investorsEcho Health VenturesHyde Park Venture PartnersMartin Ventures
A Place for Mom is a U.S. and Canadian senior care referral marketplace connecting families with senior living and home care providers.
Vernon Hills, US
Jonathan Stevens(Executive Officer)Thomas Richards(Executive Officer, Director)Christine Leahy(Executive Officer)Dennis Berger(Executive Officer)Neal Campbell(Executive Officer)Christina Rother(Executive Officer)
Co-investorsBain Capital Double Impact Fund LPBain Capital Life SciencesBain Capital Tech OpportunitiesBlue Sea CapitalClayton Dubilier & RiceCore Venture Capital+10 more
Cleerly is an AI-enabled software platform that analyzes coronary artery disease through advanced imaging analysis, providing clinically actionable insights to support heart attack prevention and personalized patient care.
AI & Machine LearningHealthtechMedical Devices
Co-investorsBreyer CapitalDigiTx Partners LLCVensana Capital
Cortica provides in-home, in-clinic, and telehealth neurological therapies for children with autism and developmental differences, integrating neurological, biomedical, behavioral, speech-language, and sensorimotor treatments.
Digital HealthHealthtechMedical DevicesSan Diego, US
Dr. Suzanne Goh(Founder)Neil Hattangadi(Executive Officer, Director)Briana Elvaiah(Executive Officer)
BoardRyan Drant(Director)inStephen Anastos(Director)Justin Brock(Director)in
Co-investors.406 VenturesAIFAPERTURE Venture PartnersCVS Health VenturesEcho Health VenturesLongitude Capital+4 more
Crosswalk builds a network of community-based first responders and EMS agencies to provide tailored, pre-hospital care for patients who do not require emergency transport, reducing unnecessary ED utilization.
Digital HealthHealthtechSaaS
Jon Collins(Co-Founder & CEO)
Co-investorsPrimary Venture Partners
Current Health builds FDA-cleared clinical technology and infrastructure that enables acute and complex care—including advanced therapies like CAR-T, bispecifics, and cell and gene therapies—to be delivered safely in ambulatory and home settings.
AI & Machine LearningDigital HealthHealthtechMedical DevicesEdinburgh, US
Christopher McGhee(Founder)in
Co-investorsMMC VenturesOSF Ventures
Daffodil Health builds pricing products and systems for healthcare payors and providers, using data, technology, and AI to automate healthcare pricing operations such as claim repricing and contracting.
AI & Machine LearningDigital HealthHealthtechInsurTechSaaS
Co-investorsFlare Capital PartnersTau VenturesMaverick Ventures
Availity is a healthcare network platform that processes eligibility, authorizations, claims, and payment transactions for providers, payers, and healthcare IT vendors.
AI & Machine LearningEnterprise SoftwareHealthtechFarmington, US
John D'Amore(Executive Officer, Director, Promoter)Eric Rosow(Executive Officer, Director, Promoter)Russ ThomasinRichard Dumler(Director)
BoardMatthew D. Storeygard(Director)in
Co-investorsExcelerate Health VenturesHLM Venture PartnersActivate Venture PartnersConnecticut InnovationsOptum Ventures
Diana is a platform for managing flexible work and HR operations.
AI & Machine LearningConsumerDigital HealthEnterprise SoftwareFuture of WorkHR TechSaaSSan Francisco, US
Upeka Bee(Founder)inDilan(Co-founder)inGautamin
Co-investorsY Combinator.406 VenturesAlleyCorpGeneral CatalystHealthQuest CapitalNorwest Venture Partners+1 more
First Light Diagnostics develops the MultiPath benchtop analyzer, an instrument for rapid diagnostic testing.
BiotechHealthtechMedical Devices
Co-investorsBayMed Venture PartnersBoston Harbor Angels
Genome Medical provides telehealth-enabled genetic services, including genetic counseling, genetic testing, and clinical trial matching, with a focus on individuals with rare conditions.
BiotechDigital HealthHealthtech
Mark Sylvester(Chief Financial Officer)Andrew Warner(Vice President, Product)Monica Zarb(Vice President, Business Development)Durand Van Arnem(Vice President, Engineering)Alan Rope(Medical Director)
Co-investorsCanaan PartnersDreamers VCEcho Health VenturesGV (Google Ventures)Illumina VenturesKaiser Permanente Ventures+3 more
Co-investorsFreshTracks Capital
Greater Good Health provides value-based primary care services for older adults, delivered through nurse practitioners and partnered with health plans, medical groups, and accountable care organizations.
Digital HealthHealthtech
Co-investorsEpsilon Health InvestorsFlare Capital PartnersMartin VenturesOptum VenturesAllumia Ventures
AgTechArlington, US
Frederick C. Lee(Executive Officer)Andrew J. Kraisinger(Executive Officer)
Co-investorsNorth Bridge Venture Partners
hellocare.ai is an end-to-end virtual care delivery platform combining software, hardware, and AI to support virtual nursing, virtual sitting, telehealth, and remote patient monitoring.
AI & Machine LearningDigital HealthHealthtechClearwater, US
Labinot Bytyqi(Founder)
Co-investorsOSF Ventures
House Rx provides a platform that enables physicians and pharmacists at specialty clinics to collaborate on medical and pharmacy care delivery.
Enterprise SoftwareHealthtechSaaS
Ogi Kavazovic(Founder)in
Co-investors1984 Ventures Management, LlcBessemer Venture PartnersCencora VenturesNew Enterprise Associates (NEA)CharacterMaverick Ventures
Life Image (now part of Intelerad, a GE HealthCare company) provides technology that connects physicians and moves medical imaging and data across the patient journey.
Digital HealthEnterprise SoftwareHealthtechMedical DevicesNewton, US
Hamid Tabatabaie(Executive Officer, Director, Promoter)
BoardDavid Jahns(Director)Thomas McKinley(Director)William Cowen(Director)in
Co-investorsCardinal Partners
Lumata Health provides a Continuous Care program for eye care practices, helping patients stay on track with appointments and treatment adherence while addressing barriers to care.
Digital HealthHealthtechOklahoma City, US
Matt Wills(Co-Founder and President)Stephen Fransen(Chairman and Co-Founder)J. Matthew Wills(Executive Officer, Director)Landon Grace(Chief Executive Officer)Nastran Andersen(Chief Growth Officer)Dana Boyd(Chief of Staff)
Co-investorsCencora VenturesCortado VenturesMcKesson VenturesWolfpack Investor Network
Main Street partners with rural healthcare providers—including private practices, rural health clinics, critical access hospitals, and community health centers across rural America—to help them operate in a value-based care model.
Digital HealthHealthtech
Co-investorsCVS Health VenturesEcho Health VenturesFrist Cressey VenturesHLM Venture PartnersOak HC/FTOptum Ventures
Medcrypt provides cybersecurity products and strategic consulting to medical device manufacturers to ensure devices are secure by design and meet regulatory requirements.
CybersecurityHealthtechMedical DevicesSaaSSan Diego, US
Mike Kijewski(Founder)inEric Pancoast(Founder)in
Co-investorsY CombinatorEniac VenturesSection 32Anzu PartnersIntuitive VenturesS32
Wellbox provides nurse-delivered chronic care management (CCM) services, offering monthly patient interactions and preventative care support for individuals with multiple chronic conditions.
Digital HealthHealthtechJacksonville, US
Nathaniel B. Findlay(Executive Officer)
BoardMatthew Downs(Director)Vincent Chiara(Director)Nashaat Daniel(Director)Ian Ihnatowycz(Director)Leonard B.C. Schlemm(Director)
Co-investorsBeresford VenturesExcelerate Health VenturesTamiami Angel
Protedyne designs robotic hardware and software infrastructure for laboratory automation, providing data management and process tracking for diagnostic testing laboratories.
BiotechMedical DevicesRobotics
Proximity is a configurable platform for managing 340B drug pricing programs, unifying data from TPAs, pharmacies, wholesalers, and payers to detect missed savings, correct claims, and support HRSA and manufacturer audit compliance.
Digital HealthHealthtechSaaS
Co-investorsCommonweal Ventures
RxLightning offers a digital platform that automates specialty medication onboarding, including enrollment forms, benefit checks, prior authorization, consent collection, and patient assistance programs.
Digital HealthHealthtechSaaSGreenville, US
Julia Regan(Executive Officer, Director, Promoter)in
BoardTaha Jangda(Director)inRichard Cohan(Director)
Co-investorsHealthX VenturesMcKesson VenturesHearst Ventures
Season provides personalized nutrition consulting through board-certified dietitians matched to patients via online assessment, with meal planning and prepared meals delivered based on individual health goals.
Digital HealthHealthtech
Josh Hix(CEO)
Co-investorsAble PartnersAndreessen HorowitzCoalition OperatorsHealthy VenturesImagination CapitalValspring Capital+4 more
Socially Determined provides social risk analytics through its SocialScape platform, combining person- and community-level data to show healthcare organizations where non-clinical factors drive costs and poor outcomes.
Data & InfrastructureDigital HealthHealthtechWashington, US
Co-investorsCorewell Health VenturesOSF VenturesQuesta CapitalZiegler Link-age Funds
San Francisco, US
Steve Bence(Executive Officer, Director)Alon Krashinsky(Executive Officer, Director)
BoardAmbar Bhattacharyya(Director)Josh Flum(Director)inAndy Mauer(Director)
Co-investorsMaverick Ventures
Xealth offers an orchestration platform for Digital Care Execution that lets clinicians prescribe digital health programs directly from the EHR, coordinate care across patients and partners, and centralize engagement and outcome data.
Digital HealthHealthtechSaaSSeattle, US
Michael McSherry(Executive Officer, Director)Aaron Sheedy(Executive Officer, Director)Sundar Balasubramanian(Executive Officer, Director)William Bryant(Director)Eric Fu(Executive Officer)
BoardAaron Martin(Director)
Co-investorsDFJMemorialCare Innovation Fund
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.
Exits · 3
IPOs and acquisitions across the tracked portfolioPhreesiaNYSE: PHRCurrent Healthacq. by Best BuyLife Imageacq. by Intelerad
Portfolio news
latest coverage across their companies
Phreesia · mychesco.com · Aug 17, 2026
Diana Health · funderintel.com · Jul 16, 2026
Diana · streetinsider.com · Jul 8, 2026
Convergent Dental · startupfundraising.com · Jun 17, 2026
Activ Surgical · nasdaqprivatemarket.com · Apr 2, 2026
Greater Good Health · finsmes.com · Mar 6, 2026
Daffodil Health · thesaasnews.com · Feb 19, 2026
Frequently asked questions
- How many investments has LRVHealth made?
- LRVHealth has 33 tracked investments, 2 of which have exited via acquisition or IPO, including 4 dated in the last 24 months.
- What stage does LRVHealth invest at?
- LRVHealth invests at the Seed, Series A, Series B, Series C, Late Stage stages.
- What is LRVHealth's typical check size?
- LRVHealth typically writes checks of $500K – $1M.
- What sectors does LRVHealth focus on?
- LRVHealth focuses on Digital Health, Healthtech, Medical Devices.
- Where is LRVHealth located?
- LRVHealth is headquartered in Boston, US.
- Does LRVHealth lead rounds?
- LRVHealth typically participates in rounds rather than leading them.
- Who does LRVHealth co-invest with?
- LRVHealth most often shares deals with OSF Ventures, Blue Venture Funds, HLM Venture Partners, among 44 tracked co-investors.
From the blog
visit blog ↗LRVHealth has recently examined infrastructure barriers limiting cell and gene therapy adoption, the practical challenges of scaling AI deployment across healthcare organizations, and how healthcare buyers should approach AI procurement through an architectural rather than point-solution lens. AI summary
Media · Podcasts & interviews
featuring the team#346 - Josh Flum, Managing Partner at LRVHealth
Slice of Healthcare Network · Josh Flum
Healthcare's Biggest AI Opportunity Isn't Clinical. It's Consumer. A Conversation with CVS Health
LRVHealth
The Pediatric Innovation Playbook: How Dayton Children’s Evaluates AI, ROI and Scale
LRVHealth
Designing Digital Change for Scale: Laura Wilt on AI, Leadership & the Human Side of Transformation
LRVHealth
Why Healthcare Leadership Is Harder Than Ever: Cedars-Sinai’s Tom Priselac on Culture, Change & Cost
LRVHealth
A Giant Leap for Healthcare: Dr. Wachter on AI, Clinical Workflows & the Patient-Doctor Relationship
LRVHealth
Images
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